USC.edu
Are You a Patient?

John Paul Murad

Assistant Professor of Research Medicine

Image of John Paul Murad
Is this your profile? Click to edit
Email johnmura@usc.edu
CTSI Profile

Publications

  • Nonsignaling extracellular spacer regulates tumor antigen selectivity of CAR T cells Mol Ther Oncol. 2024 Jun 20; 32(2):200789. . View in PubMed
  • PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial Nat Med. 2024 Jun; 30(6):1636-1644. . View in PubMed
  • Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting bioRxiv. 2023 Jan 07. . View in PubMed
  • Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting Nat Commun. 2023 08 07; 14(1):4737. . View in PubMed
  • Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control Nat Biomed Eng. 2021 11; 5(11):1348-1359. . View in PubMed
  • Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity Mol Ther. 2021 07 07; 29(7):2335-2349. . View in PubMed
  • Effective combination immunotherapy using oncolytic viruses to deliver CAR targets to solid tumors Sci Transl Med. 2020 09 02; 12(559). . View in PubMed
  • Regional Delivery of Chimeric Antigen Receptor-Engineered T Cells Effectively Targets HER2+ Breast Cancer Metastasis to the Brain Clin Cancer Res. 2018 01 01; 24(1):95-105. . View in PubMed
  • Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA+ metastatic prostate cancer Oncoimmunology. 2018; 7(2):e1380764. . View in PubMed
  • Effective Targeting of TAG72+ Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells Front Immunol. 2018; 9:2268. . View in PubMed
  • Human brain metastatic stroma attracts breast cancer cells via chemokines CXCL16 and CXCL12 NPJ Breast Cancer. 2017; 3:6. . View in PubMed
  • Antigen-specific inhibition of high-avidity T cell target lysis by low-avidity T cells via trogocytosis Cell Rep. 2014 Aug 07; 8(3):871-882. . View in PubMed
  • Current and experimental antibody-based therapeutics: insights, breakthroughs, setbacks and future directions Curr Mol Med. 2013 Jan; 13(1):165-78. . View in PubMed
  • Thromboxane A2 receptor: biology and function of a peculiar receptor that remains resistant for therapeutic targeting J Cardiovasc Pharmacol Ther. 2012 Sep; 17(3):248-59. . View in PubMed
  • Characterization of the in vivo antiplatelet activity of the antihypertensive agent losartan J Cardiovasc Pharmacol Ther. 2012 Sep; 17(3):308-14. . View in PubMed
  • A novel antibody targeting the ligand binding domain of the thromboxane A2 receptor exhibits antithrombotic properties in vivo Biochem Biophys Res Commun. 2012 May 11; 421(3):456-61. . View in PubMed
  • Mouse transient receptor potential channel 6: role in hemostasis and thrombogenesis Biochem Biophys Res Commun. 2012 Jan 13; 417(2):853-6. . View in PubMed
  • Aspirin: pharmacology and clinical applications Thrombosis. 2012; 2012:173124. . View in PubMed
  • The C-terminal segment of the second extracellular loop of the thromboxane A2 receptor plays an important role in platelet aggregation Biochem Pharmacol. 2012 Jan 01; 83(1):88-96. . View in PubMed

Similar People