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Jonathan Nelson, PhD

Assistant Professor of Medicine

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Email [email protected]
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Overview

Jonathan Nelson is an Assistant Professor in the Division of Nephrology & Hypertension at the USC Keck School of Medicine. A native of the Pacific Northwest, Dr. Nelson attended the University of Washington for his undergraduate degree in Biochemistry before pursuing a PhD in Molecular and Medical Genetics at Oregon Health & Science University. Dr. Nelson trained in multiple clinical departments at Oregon Health & Science University including Anesthesiology and Perioperative Medicine, the Knight Cardiovascular Institute, and the Division of Nephrology & Hypertension. His research focuses on the intersection of vascular biology and medicine with an emphasis on understanding the role of the renin angiotensin system in regulating the kidney microvasculature. His research has been funded by the National Institutes of Health, American Heart Association, and Collins Medical Trust.

Publications

  • Proximal tubule ACE2 mediates early responses to hypertension by regulating intrarenal RAS and sodium homeostasis. JCI Insight. 2026 Sep 22; 11(18).. View in PubMed
  • Renal PIEZO2 is an essential regulator of renin. Cell. 2026 Jan 08; 189(1):161-178.e22.. View in PubMed
  • Inhibition of methylthioadenosine phosphorylase protects from experimental acute kidney injury. Am J Physiol Renal Physiol. 2025 08 01; 329(2):F250-F256.. View in PubMed
  • Cardiac LIM Protein, Kidney Fibrosis, and Vascular Change after Acute Cardiorenal Syndrome. J Am Soc Nephrol. 2025 Dec 01; 36(12):2330-2347.. View in PubMed
  • Distinct cell types along thick ascending limb express pathways for monovalent and divalent cation transport. JCI Insight. 2025 07 08; 10(13).. View in PubMed
  • Effect of sex chromosome complement versus gonadal hormones on abundance of renal transporters. Am J Physiol Renal Physiol. 2025 05 01; 328(5):F638-F646.. View in PubMed
  • Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury. Physiol Genomics. 2025 04 01; 57(4):266-278.. View in PubMed
  • Remyelination protects neurons from DLK-mediated neurodegeneration. Nat Commun. 2024 10 23; 15(1):9148.. View in PubMed
  • Optimizing renal transporter immunodetection: consequences of freeze-thaw during sample preparation. Am J Physiol Renal Physiol. 2024 10 01; 327(4):F655-F666.. View in PubMed
  • Angiotensin II Directly Increases Endothelial Calcium and Nitric Oxide in Kidney and Brain Microvessels In Vivo With Reduced Efficacy in Hypertension. J Am Heart Assoc. 2024 05 21; 13(10):e033998.. View in PubMed

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