Joni Kristin Doherty, MD, PhD

Dr. Joni Kristin Doherty’s clinic interests include chronic ear disease, otosclerosis, cochlear implantation, vestibular disorders, and skull base tumors including acoustic neuromas and meningiomas.

Dr. Doherty has conducted cutting-edge research on the genetics and biology of inner ear disorders at the House Ear Institute, the University of California, San Diego, and the University of California, Los Angeles funded by the National Institutes of Health (NIH).

Dr. Doherty has authored numerous research publications and textbook chapters in her field. She is a member of the American Academy of Otolaryngology – Head and Neck Surgery. Dr. Doherty is committed to offering high quality, compassionate care to patients in her clinic, while pursuing clinical advancements in the field of Otology & Neurotology.

Dr. Doherty graduated with Honors from UCLA, and earned her medical degree and doctorate degree (PhD) in Cell Biology from The Oregon Health & Sciences University. She completed her residency in Otolaryngology –Head and Neck Surgery here at our very own University of Southern California and her fellowship at the world renowned House Clinic in Los Angeles.

After fellowship, she joined the faculty at UCSD and was awarded an NIH training grant for her research on vestibular schwannoma (a.k.a., acoustic neuroma) biology. She later joined the House Research Institute as a senior scientist while working half-time in Neurotology practice in Orange County before joining USC.

USC Caruso Department of Otolaryngology – Head & Neck Surgery

• External Auditory Canal Exostosis and the California Surfer Population: A Cross-Sectional Study Laryngoscope. 2025 Jan; 135(1):286-292. . View in PubMed
• Music to Define a Generation: Factors Associated With Hearing Protection Use at Music Venues Otol Neurotol. 2024 Aug 01; 45(7):745-753. . View in PubMed
• Utilization of Face-to-Face Vestibular Support Groups: A Comparison to Online Group Participation Ann Otol Rhinol Laryngol. 2024 Aug; 133(8):713-719. . View in PubMed
• Disparities in Sporadic Vestibular Schwannoma Initial Presentation Between a Public Safety Net Hospital and Tertiary Academic Medical Center at the Same Zip Code 2010 to 2020 Ann Otol Rhinol Laryngol. 2024 Jun; 133(6):605-612. . View in PubMed
• Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma J Neurooncol. 2024 Apr; 167(2):339-348. . View in PubMed
• New Paradigm of Music Listening: Hearing Protection Perceptions and Treatment Decision-Making Among Music Venue Attendees Otolaryngol Head Neck Surg. 2024 Mar; 170(3):776-787. . View in PubMed
• Association between Cannabis Use and Tinnitus in US Adults Otol Neurotol. 2023 07 01; 44(6):611-618. . View in PubMed
• An Exploration of Online Support Community Participation Among Patients With Vestibular Disorders Laryngoscope. 2022 09; 132(9):1835-1842. . View in PubMed
• Headache in Pregnancy Otolaryngol Clin North Am. 2022 Jun; 55(3):681-696. . View in PubMed
• Comprehensive Management of Headache for the Otolaryngologist: A Summary Otolaryngol Clin North Am. 2022 Jun; 55(3S):e1-e8. . View in PubMed
• Nummular and Side-locked Headaches for the Otolaryngologist Otolaryngol Clin North Am. 2022 Jun; 55(3):697-706. . View in PubMed
• Idiopathic Intracranial Hypertension: Implications for the Otolaryngologist Otolaryngol Clin North Am. 2022 Jun; 55(3):579-594. . View in PubMed
• Comprehensive Headache Evaluation and Management for the Otolaryngologist Otolaryngol Clin North Am. 2022 06; 55(3):xvii-xviii. . View in PubMed
• Temporomandibular Joint Syndrome from an Ear Versus Dental-Related Standpoint Otolaryngol Clin North Am. 2022 Jun; 55(3):649-658. . View in PubMed
• Trends in Hearing Protection Use With Occupational Noise Exposure in the United States 1999 to 2016 Otol Neurotol. 2022 01 01; 43(1):e14-e22. . View in PubMed
• Prevalence of Tinnitus and Associated Factors Among Asian Americans: Results From a National Sample Laryngoscope. 2020 12; 130(12):E933-E940. . View in PubMed
• Comparing Light-Driven Contact Hearing Aids with Acoustic Hearing Aids: Data and Clinical Tips Audiol Neurootol. 2020; 25(5):283-290. . View in PubMed
• Contributions of Contemporary Human Temporal Bone Histopathology to Clinical Otology Otolaryngol Head Neck Surg. 2019 11; 161(5):725-733. . View in PubMed
• Quality improvement in neurology: Neuro-otology quality measurement set Neurology. 2018 10 09; 91(15):697-701. . View in PubMed
• Quality Improvement in Neurology: Neurotology Quality Measurement Set Otolaryngol Head Neck Surg. 2018 10; 159(4):603-607. . View in PubMed
• Cochlear implant histopathology World J Otorhinolaryngol Head Neck Surg. 2017 Dec; 3(4):211-213. . View in PubMed
• Post Hybrid Cochlear Implant Hearing Loss and Endolymphatic Hydrops Otol Neurotol. 2016 12; 37(10):1516-1521. . View in PubMed
• Identification of target proteins involved in cochlear otosclerosis Otol Neurotol. 2015 Jun; 36(5):923-31. . View in PubMed
• Schwannomas exhibit distinct size-dependent gene-expression patterns Future Oncol. 2015; 11(12):1751-8. . View in PubMed
• Neurofibromatosis 2 invasion of the internal auditory canal wall: clinical significance Otol Neurotol. 2014 Oct; 35(9):1662-8. . View in PubMed
• Novel age-dependent targets in vestibular schwannomas Hum Genomics. 2014 Jun 30; 8:10. . View in PubMed
• The periductal channels of the endolymphatic duct, hydrodynamic implications Otolaryngol Head Neck Surg. 2014 Mar; 150(3):441-7. . View in PubMed
• Idiopathic sudden sensorineural hearing loss: vascular or viral? Otolaryngol Head Neck Surg. 2013 Dec; 149(6):914-7.. View in PubMed
• Temporal bone histopathology case of the month: Incidental discovery of a temporal bone chondroblastoma on an archived histopathologic section Otol Neurotol. 2013 Jul; 34(5):e38-9. . View in PubMed
• Short-term histopathology effects of gamma knife radiosurgery on a vestibular schwannoma Otolaryngol Head Neck Surg. 2013 Jun; 148(6):1056-8. . View in PubMed
• Recurrent schwannoma postirradiation: histological review reveals mixed schwannoma and meningioma Otolaryngol Head Neck Surg. 2013 May; 148(5):886-8. . View in PubMed
• Adipose replacing intracochlear architecture after meningioma removal Otol Neurotol. 2013 Feb; 34(2):e8-9. . View in PubMed
• Temporal bone histopathology case of the month: Modiolar dehiscence associated with sensorineural hearing loss Otol Neurotol. 2013 Jan; 34(1):e4-5. . View in PubMed
• Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas Otol Neurotol. 2012 Dec; 33(9):1640-7. . View in PubMed
• Round window versus cochleostomy technique in cochlear implantation: histologic findings Otol Neurotol. 2012 Sep; 33(7):1181-7. . View in PubMed
• ErbB expression, activation, and inhibition with lapatinib and tyrphostin (AG825) in human vestibular schwannomas Otol Neurotol. 2011 Jul; 32(5):841-7. . View in PubMed
• Comparative case series of exostoses and osteomas of the internal auditory canal Ann Otol Rhinol Laryngol. 2011 Apr; 120(4):255-60. . View in PubMed
• EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma Otol Neurotol. 2011 Feb; 32(2):308-14. . View in PubMed
• Estrogen receptor expression in sporadic vestibular schwannomas Otol Neurotol. 2011 Jan; 32(1):158-62. . View in PubMed
• Potential role of imatinib mesylate (Gleevec, STI-571) in the treatment of vestibular schwannoma Otol Neurotol. 2011 Jan; 32(1):163-70. . View in PubMed
• Endolymphatic sac shunt, labyrinthectomy, and vestibular nerve section in Meniere’s disease Otolaryngol Clin North Am. 2010 Oct; 43(5):1091-111. . View in PubMed
• Merlin knockdown in human Schwann cells: clues to vestibular schwannoma tumorigenesis Otol Neurotol. 2010 Apr; 31(3):460-6. . View in PubMed
• Laterality of exostosis in surfers due to evaporative cooling effect Otol Neurotol. 2010 Feb; 31(2):345-51. . View in PubMed
• Exostoses and osteomas of the internal auditory canal Laryngoscope. 2010; 120 Suppl 4:S215. . View in PubMed
• Concordance of bilateral vestibular schwannoma growth and hearing changes in neurofibromatosis 2: neurofibromatosis 2 natural history consortium Otol Neurotol. 2009 Sep; 30(6):835-41. . View in PubMed
• Cellular targeting for cochlear gene therapy Adv Otorhinolaryngol. 2009; 66:99-115. . View in PubMed
• Vestibular schwannoma quantitative polymerase chain reaction expression of estrogen and progesterone receptors Laryngoscope. 2008 Aug; 118(8):1458-63. . View in PubMed
• ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy Otol Neurotol. 2008 Jan; 29(1):50-7. . View in PubMed
• Distribution of nonvestibular cranial nerve schwannomas in neurofibromatosis 2 Otol Neurotol. 2007 Dec; 28(8):1083-90. . View in PubMed
• Facial palsy and fallopian canal expansion associated with idiopathic intracranial hypertension Otol Neurotol. 2007 Aug; 28(5):715-8. . View in PubMed
• CPA melanoma: diagnosis and management Otol Neurotol. 2007 Jun; 28(4):529-37. . View in PubMed
• Endolymphatic sac tumor: a report of 3 cases and discussion of management Ear Nose Throat J. 2007 Jan; 86(1):30-5. . View in PubMed
• Controversies in building a management algorithm for vestibular schwannomas Curr Opin Otolaryngol Head Neck Surg. 2006 Oct; 14(5):305-13. . View in PubMed
• Meniere’s disease: prevalence of contralateral ear involvement Otol Neurotol. 2006 Apr; 27(3):355-61. . View in PubMed
• Ossicular discontinuity and exostoses in Proteus syndrome: a case report Ann Otol Rhinol Laryngol. 2005 Mar; 114(3):242-6. . View in PubMed
• Cochlear endosteal erosion with focal osteomyelitis induced by cochlear implantation Otol Neurotol. 2004 Nov; 25(6):1029-30. . View in PubMed
• Spiral ligament and stria vascularis changes in cochlear otosclerosis: effect on hearing level Otol Neurotol. 2004 Jul; 25(4):457-64. . View in PubMed
• Pathology quiz case 2Pemphigus vulgaris (PV). Arch Otolaryngol Head Neck Surg. 2003 Feb; 129(2):254256-7. . View in PubMed
• Autologous fat grafting for the refractory patulous eustachian tube Otolaryngol Head Neck Surg. 2003 Jan; 128(1):88-91. . View in PubMed
• Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor Oncogene. 2001 Aug 23; 20(37):5199-209. . View in PubMed

• Oghalai, John
• Shera, Christopher
• Choi, Janet
• Cohen-Gadol, Aaron
• Friedland, David