Keck School Faculty

A Multicenter Retrospective Chart Review of Clinical Outcomes Among Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer Clin Lung Cancer. 2023 Feb 08. . View in PubMed

Multianalyte liquid biopsy to aid the diagnostic workup of breast cancer NPJ Breast Cancer. 2022 Sep 27; 8(1):112. . View in PubMed

Retrospective Analysis of Real-World Management of EGFR-Mutated Advanced NSCLC, After First-Line EGFR-TKI Treatment: US Treatment Patterns, Attrition, and Survival Data Drugs Real World Outcomes. 2022 Sep; 9(3):333-345. . View in PubMed

Characterization of Cellular and Acellular Analytes from Pre-Cystectomy Liquid Biopsies in Patients Newly Diagnosed with Primary Bladder Cancer Cancers (Basel). 2022 Feb 01; 14(3). . View in PubMed

Evaluating Real World Mutational Differences Between Hispanics and Asians in NSCLC at a Large Academic Institution in Los Angeles Clin Lung Cancer. 2022 11; 23(7):e443-e452. . View in PubMed

Effect of sponsor on enrollment criteria in non-small cell lung cancer clinical trials J Cancer Policy. 2022 09; 33:100336. . View in PubMed

NTRK1 Fusions identified by non-invasive plasma next-generation sequencing (NGS) across 9 cancer types Br J Cancer. 2022 02; 126(3):514-520. . View in PubMed

Characterization of mortality and high-risk characteristics of thyroid cancer in Filipinos using the California Cancer Registry Front Public Health. 2022; 10:1104607. . View in PubMed

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Oncotarget. 2021 Dec 07; 12(25):2449-2458. . View in PubMed

Blood-Based Multi-Cancer Detection Using a Novel Variant Calling Assay (DEEPGENTM): Early Clinical Results Cancers (Basel). 2021 Aug 15; 13(16). . View in PubMed

Effect of prior therapy on tumor mutational burden in NSCLC Transl Lung Cancer Res. 2021 Mar; 10(3):1231-1238. . View in PubMed

Characterization of KRAS Mutation Subtypes in Non-small Cell Lung Cancer Mol Cancer Ther. 2021 12; 20(12):2577-2584. . View in PubMed

Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC) Lung Cancer. 2021 10; 160:92-98. . View in PubMed

Clinical management of immune-related adverse events following immunotherapy treatment in patients with non-small cell lung cancer J Investig Med. 2021 10; 69(7):1281-1286. . View in PubMed

Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient Cold Spring Harb Mol Case Stud. 2020 12; 6(6). . View in PubMed

Use of Wearable Activity Tracker in Patients With Cancer Undergoing Chemotherapy: Toward Evaluating Risk of Unplanned Health Care Encounters JCO Clin Cancer Inform. 2020 09; 4:839-853. . View in PubMed

Quantified Kinematics to Evaluate Patient Chemotherapy Risks in Clinic JCO Clin Cancer Inform. 2020 06; 4:583-601. . View in PubMed

Intravenous 5-fluoro-2'-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors Cancer Chemother Pharmacol. 2020 05; 85(5):979-993. . View in PubMed

Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients J Mol Diagn. 2020 03; 22(3):319-337. . View in PubMed

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials Lancet Oncol. 2020 02; 21(2):271-282. . View in PubMed

A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study J Thorac Oncol. 2020 01; 15(1):110-119. . View in PubMed

A Systematic Review of the Efficacy of Preclinical Models of Lung Cancer Drugs Front Oncol. 2020; 10:591. . View in PubMed

Trimodality vs Chemoradiation and Salvage Resection in cN2 Stage IIIA Non-Small Cell Lung Cancer Semin Thorac Cardiovasc Surg. 2020; 32(1):153-159. . View in PubMed

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Oncotarget. 2019 Dec 17; 10(66):7016-7030. . View in PubMed

Detection of NRG1 Gene Fusions in Solid Tumors Clin Cancer Res. 2019 Aug 15; 25(16):4966-4972. . View in PubMed

Patient reported outcomes can improve performance status assessment: a pilot study J Patient Rep Outcomes. 2019 Jul 16; 3(1):41. . View in PubMed

Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer J Thorac Oncol. 2019 11; 14(11):1901-1911. . View in PubMed

Radiomics in Pulmonary Lesion Imaging AJR Am J Roentgenol. 2019 03; 212(3):497-504. . View in PubMed

Tuberculosis following PD-1 blockade for cancer immunotherapy Sci Transl Med. 2019 01 16; 11(475). . View in PubMed

Mandatory Research Biopsy Requirements Delay Initiation of Clinical Trials Front Oncol. 2019; 9:968. . View in PubMed

Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer J Transl Med. 2019 08 28; 17(1):294. . View in PubMed

A new anion exchange purification method for Cu stable isotopes in blood samples Anal Bioanal Chem. 2019 Jan; 411(3):765-776. . View in PubMed

Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay Arch Pathol Lab Med. 2018 Feb; 142(2):198-207. . View in PubMed

Low-dimensional dynamical characterization of human performance of cancer patients using motion data Clin Biomech (BristolAvon). 2018 07; 56:61-69. . View in PubMed

When it comes to genomic analysis of tumours, don't buy in bulk Br J Cancer. 2018 05; 118(10):1281-1282. . View in PubMed

Development of metastatic brain disease involves progression through lung metastases in EGFR mutated non-small cell lung cancer Converg Sci Phys Oncol. 2017 Sep; 3(3). . View in PubMed

Biophysical technologies for understanding circulating tumor cell biology and metastasis Transl Lung Cancer Res. 2017 Aug; 6(4):473-485. . View in PubMed

Cellular Expression of PD-L1 in the Peripheral Blood of Lung Cancer Patients is Associated with Worse Survival Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1139-1145. . View in PubMed

A Randomized Phase II Study of Linsitinib (OSI-906) Versus Topotecan in Patients With Relapsed Small-Cell Lung Cancer Oncologist. 2016 10; 21(10):1163-1164. . View in PubMed

Oncolytic viruses: perspectives on clinical development Curr Opin Virol. 2015 Aug; 13:55-60. . View in PubMed

A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma Oral Oncol. 2015 Apr; 51(4):376-82. . View in PubMed

Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites NPJ Breast Cancer. 2015; 1:15018. . View in PubMed

Entropy, complexity, and Markov diagrams for random walk cancer models Sci Rep. 2014 Dec 19; 4:7558. . View in PubMed

Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer J Thorac Oncol. 2014 Aug; 9(8):1111-9. . View in PubMed

Adrenal metastases in lung cancer: clinical implications of a mathematical model J Thorac Oncol. 2014 Apr; 9(4):442-6. . View in PubMed

Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients Cancer. 2013 Jul 01; 119(13):2383-90. . View in PubMed

Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte Carlo mathematical model Cancer Res. 2013 May 01; 73(9):2760-9. . View in PubMed

An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer PLoS One. 2013; 8(7):e67733. . View in PubMed

Fluid biopsy for solid tumors: a patient's companion for lifelong characterization of their disease Future Oncol. 2012 Aug; 8(8):989-98. . View in PubMed

ERCC1 expression in circulating tumor cells (CTCs) using a novel detection platform correlates with progression-free survival (PFS) in patients with metastatic non-small-cell lung cancer (NSCLC) receiving platinum chemotherapy Lung Cancer. 2012 Aug; 77(2):421-6. . View in PubMed

Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology Phys Biol. 2012 Feb; 9(1):016005. . View in PubMed

Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors Phys Biol. 2012 Feb; 9(1):016001. . View in PubMed

Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers Phys Biol. 2012 Feb; 9(1):016003. . View in PubMed

High-definition imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis Phys Biol. 2012 Feb; 9(1):016004. . View in PubMed

A stochastic Markov chain model to describe lung cancer growth and metastasis PLoS One. 2012; 7(4):e34637. . View in PubMed

A pilot study of long-acting octreotide for symptomatic malignant ascites Oncology. 2012; 82(6):315-20. . View in PubMed

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans Nature. 2011 Aug 31; 477(7362):99-102. . View in PubMed

Cholesterol secosterol aldehydes induce amyloidogenesis and dysfunction of wild-type tumor protein p53 Chem Biol. 2011 Jul 29; 18(7):920-7. . View in PubMed

Cytomorphology of circulating colorectal tumor cells:a small case series J Oncol. 2010; 2010:861341. . View in PubMed

Circulating tumor cells from well-differentiated lung adenocarcinoma retain cytomorphologic features of primary tumor type Arch Pathol Lab Med. 2009 Sep; 133(9):1468-71. . View in PubMed

The ratio of cholesterol 5,6-secosterols formed from ozone and singlet oxygen offers insight into the oxidation of cholesterol in vivo Chem Commun (Camb). 2009 Jun 07; (21):3098-100. . View in PubMed

Purification and characterization of sideroblasts from patients with acquired and hereditary sideroblastic anaemia Br J Haematol. 2008 Nov; 143(3):446-50. . View in PubMed

Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation Biochemistry. 2008 Jul 22; 47(29):7695-705. . View in PubMed

Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients Thromb Res. 2008; 122(5):604-9. . View in PubMed

Understanding hairy cell leukemia genetics Leuk Lymphoma. 2007 Apr; 48(4):653-4. . View in PubMed

The clinical significance of circulating tissue factor in prostate cancer Thromb Haemost. 2007 Mar; 97(3):329-30. . View in PubMed

Case study of the morphologic variation of circulating tumor cells Hum Pathol. 2007 Mar; 38(3):514-9. . View in PubMed

AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP N Engl J Med. 2006 Oct 19; 355(16):1672-81. . View in PubMed

Use of optophoresis as an in vitro predictor of cell response to chemotherapy for chronic lymphocytic leukemia Leuk Lymphoma. 2006 Oct; 47(10):2194-202. . View in PubMed

Proatherogenic effects of the cholesterol ozonolysis products, atheronal-A and atheronal-B Biochemistry. 2006 Jun 13; 45(23):7162-70. . View in PubMed

Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization Nat Chem Biol. 2006 May; 2(5):249-53. . View in PubMed

High speed detection of circulating tumor cells Biosens Bioelectron. 2006 Apr 15; 21(10):1893-9. . View in PubMed

Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway Immunol Lett. 2006 Feb 28; 103(1):33-8. . View in PubMed

SHP1 expression in bone marrow biopsies of myelodysplastic syndrome patients: a new prognostic factor Br J Haematol. 2005 Jun; 129(6):791-4. . View in PubMed

The antibody-catalyzed water oxidation pathway--a new chemical arm to immune defense? Trends Biochem Sci. 2004 May; 29(5):274-8.. View in PubMed

Metabolite-initiated protein misfolding may trigger Alzheimer's disease Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):4752-7. . View in PubMed

Cladribine activity in systemic mast cell disease: application of biochemistry in the modern era of molecular biology Leuk Res. 2004 Feb; 28(2):113-4. . View in PubMed

Evidence for ozone formation in human atherosclerotic arteries Science. 2003 Nov 07; 302(5647):1053-6. . View in PubMed

Phase 2 study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia Blood. 2003 Aug 01; 102(3):810-3. . View in PubMed

Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation Science. 2002 Dec 13; 298(5601):2195-9. . View in PubMed

Injuries in youth ice hockey: a pilot surveillance strategy Mayo Clin Proc. 1995 Apr; 70(4):350-6. . View in PubMed