Keck School Faculty

Juan Pablo Lewinger

Juan Pablo Lewinger

Assistant Professor of Clinical Population and Public Health Sciences
SSB 202U 2001 N. Soto Street Health Sciences Campus Los Angeles

Genome-wide interaction analysis of folate for colorectal cancer risk Am J Clin Nutr. 2023 Aug 26. . View in PubMed

A note on p-value multiple-testing adjustment for two-step genome-wide gene-environment interactions scans medRxiv. 2023 Jun 28. . View in PubMed

Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses Br J Cancer. 2023 08; 129(3):511-520. . View in PubMed

Improved two-step testing of genome-wide gene-environment interactions Genet Epidemiol. 2023 03; 47(2):152-166. . View in PubMed

Prenatal exposure to tailpipe and non-tailpipe tracers of particulate matter pollution and autism spectrum disorders Environ Int. 2023 01; 171:107736. . View in PubMed

Classification of Angle Closure Severity by Hierarchical Cluster Analysis of Ocular Biometrics in the Dark and Light Transl Vis Sci Technol. 2023 09 01; 12(9):4. . View in PubMed

A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk Cancer Res. 2023 08 01; 83(15):2572-2583. . View in PubMed

Genome-wide Interaction Study with Smoking for Colorectal Cancer Risk Identifies Novel Genetic Loci Related to Tumor Suppression, Inflammation, and Immune Response Cancer Epidemiol Biomarkers Prev. 2023 03 06; 32(3):315-328. . View in PubMed

PEACOCK: a machine learning approach to assess the validity of cell type-specific enhancer-gene regulatory relationships NPJ Syst Biol Appl. 2023 04 03; 9(1):9. . View in PubMed

Associations of Autism Spectrum Disorder with PM25 Components: A Comparative Study Using Two Different Exposure Models. Environ Sci Technol. 2022 Dec 22. . View in PubMed

Effect of UNOS policy change and exception status request on outcomes in patients bridged to heart transplant with an intra-aortic balloon pump Artif Organs. 2022 May; 46(5):838-849. . View in PubMed

Genome-Wide Interaction Analysis of Genetic Variants With Menopausal Hormone Therapy for Colorectal Cancer Risk J Natl Cancer Inst. 2022 08 08; 114(8):1135-1148. . View in PubMed

Two-step hypothesis testing to detect gene-environment interactions in a genome-wide scan with a survival endpoint Stat Med. 2022 04 30; 41(9):1644-1657. . View in PubMed

A scalable hierarchical lasso for gene-environment interactions J Comput Graph Stat. 2022; 31(4):1091-1103. . View in PubMed

Hierarchical Ridge Regression for Incorporating Prior Information in Genomic Studies J Data Sci. 2022 Jan; 20(1):34-50. . View in PubMed

Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q242 Region. Cancer Epidemiol Biomarkers Prev. 2022 05 04; 31(5):1077-1089. . View in PubMed

Interactions between folate intake and genetic predictors of gene expression levels associated with colorectal cancer risk Sci Rep. 2022 11 07; 12(1):18852. . View in PubMed

Differences in Ocular Biometric Measurements among Subtypes of Primary Angle Closure Disease: The Chinese American Eye Study Ophthalmol Glaucoma. 2021 Mar-Apr; 4(2):224-231. . View in PubMed

Incorporating prior knowledge into regularized regression Bioinformatics. 2021 05 01; 37(4):514-521. . View in PubMed

Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk Cancer Med. 2020 05; 9(10):3563-3573. . View in PubMed

Female vulnerability to the effects of smoking on health outcomes in older people PLoS One. 2020; 15(6):e0234015. . View in PubMed

PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence PLoS One. 2020; 15(12):e0243791. . View in PubMed

Improvements to the Escalation with Overdose Control design and a comparison with the restricted Continual Reassessment Method Pharm Stat. 2019 11; 18(6):659-670. . View in PubMed

Preoperative hemoglobin A1c levels and increased risk of adverse limb events in diabetic patients undergoing infrainguinal lower extremity bypass surgery in the Vascular Quality InitiativeJ Vasc Surg. 2019 10; 70(4):1225-1234. e1. . View in PubMed

Genet Epidemiol. 2019 03; 43(2):150-165. . View in PubMed

A Unified Model for the Analysis of Gene-Environment Interaction Am J Epidemiol. 2019 04 01; 188(4):760-767. . View in PubMed

Correlation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study Ophthalmol Glaucoma. 2018 Nov-Dec; 1(3):158-166. . View in PubMed

Data integration by multi-tuning parameter elastic net regression BMC Bioinformatics. 2018 Oct 10; 19(1):369. . View in PubMed

Comparison of devices used in carotid artery stenting: A vascular quality initiative analysis of commonly used carotid stents and embolic protection devices Catheter Cardiovasc Interv. 2018 10 01; 92(4):743-749. . View in PubMed

Update on the State of the Science for Analytical Methods for Gene-Environment Interactions Am J Epidemiol. 2017 Oct 01; 186(7):762-770. . View in PubMed

Increased risk of mortality after lower extremity bypass in individuals with acute kidney injury in the Vascular Quality Initiative J Vasc Surg. 2017 Apr; 65(4):1055-1061. . View in PubMed

Adaptive Set-Based Methods for Association Testing Genet Epidemiol. 2016 Feb; 40(2):113-22. . View in PubMed

Novel Gene Expression Signature Predictive of Clinical Recurrence After Radical Prostatectomy in Early Stage Prostate Cancer Patients Prostate. 2016 10; 76(14):1239-56. . View in PubMed

Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls Hum Genet. 2016 08; 135(8):963. . View in PubMed

Detecting Gene-Environment Interactions for a Quantitative Trait in a Genome-Wide Association Study Genet Epidemiol. 2016 07; 40(5):394-403. . View in PubMed

Radical Prostatectomy or External Beam Radiation Therapy vs No Local Therapy for Survival Benefit in Metastatic Prostate Cancer: A SEER-Medicare Analysis J Urol. 2015 Aug; 194(2):378-85. . View in PubMed

Meat intake, cooking methods, dietary carcinogens, and colorectal cancer risk: findings from the Colorectal Cancer Family Registry Cancer Med. 2015 Jun; 4(6):936-52. . View in PubMed

Hormone metabolism pathway genes and mammographic density change after quitting estrogen and progestin combined hormone therapy in the California Teachers Study Breast Cancer Res. 2014 Dec 11; 16(6):477. . View in PubMed

Tobacco smoking, polymorphisms in carcinogen metabolism enzyme genes, and risk of localized and advanced prostate cancer: results from the California Collaborative Prostate Cancer Study Cancer Med. 2014 Dec; 3(6):1644-55. . View in PubMed

Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai Int J Cancer. 2014 Jul 15; 135(2):335-47. . View in PubMed

Angiogenesis genes, dietary oxidative balance and breast cancer risk and progression: the Breast Cancer Health Disparities Study Int J Cancer. 2014 Feb 01; 134(3):629-44. . View in PubMed

Null association between histology of first and second primary malignancies in men with bilateral testicular germ cell tumors Am J Epidemiol. 2013 Oct 15; 178(8):1240-5. . View in PubMed

Finding novel genes by testing G × E interactions in a genome-wide association study Genet Epidemiol. 2013 Sep; 37(6):603-13. . View in PubMed

Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23 Hum Mol Genet. 2013 Jul 01; 22(13):2748-53. . View in PubMed

Efficient two-step testing of gene-gene interactions in genome-wide association studies Genet Epidemiol. 2013 Jul; 37(5):440-51. . View in PubMed

Hormone metabolism genes and mammographic density in Singapore Chinese women Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):984-6. . View in PubMed

Genetic admixture and risk of hypertensive disorders of pregnancy among Latinas in Los Angeles County Epidemiology. 2013 Mar; 24(2):285-94. . View in PubMed

Confounding and heterogeneity in genetic association studies with admixed populations Am J Epidemiol. 2013 Feb 15; 177(4):351-60. . View in PubMed

Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls Hum Genet. 2013 05; 132(5):579-89. . View in PubMed

Genetic variation in the base excision repair pathway, environmental risk factors, and colorectal adenoma risk PLoS One. 2013; 8(8):e71211. . View in PubMed

Variants in tamoxifen metabolizing genes: a case-control study of contralateral breast cancer risk in the WECARE study Int J Mol Epidemiol Genet. 2013; 4(1):35-48. . View in PubMed

Red meat and poultry, cooking practices, genetic susceptibility and risk of prostate cancer: results from a multiethnic case-control study Carcinogenesis. 2012 Nov; 33(11):2108-18. . View in PubMed

Polymorphisms in carcinogen metabolism enzymes, fish intake, and risk of prostate cancer Carcinogenesis. 2012 Jul; 33(7):1352-9. . View in PubMed

Invited commentary: GE-Whiz! Ratcheting gene-environment studies up to the whole genome and the whole exposome Am J Epidemiol. 2012 Feb 01; 175(3):203-7; discussion 208-9. . View in PubMed

Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics Front Endocrinol (Lausanne). 2012; 3:182. . View in PubMed

Using extreme phenotype sampling to identify the rare causal variants of quantitative traits in association studies Genet Epidemiol. 2011 Dec; 35(8):790-9. . View in PubMed

Genotype-environment interactions in microsatellite stable/microsatellite instability-low colorectal cancer: results from a genome-wide association study Cancer Epidemiol Biomarkers Prev. 2011 May; 20(5):758-66. . View in PubMed

Sample size requirements to detect gene-environment interactions in genome-wide association studies Genet Epidemiol. 2011 Apr; 35(3):201-10. . View in PubMed

The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort Breast Cancer Res. 2011 Apr 01; 13(2):R37. . View in PubMed

Efficient genome-wide association testing of gene-environment interaction in case-parent trios Am J Epidemiol. 2010 Jul 01; 172(1):116-22. . View in PubMed

Genes involved with folate uptake and distribution and their association with colorectal cancer risk Cancer Causes Control. 2010 Apr; 21(4):597-608. . View in PubMed

Methodological Issues in Multistage Genome-wide Association Studies Stat Sci. 2009 Nov 01; 24(4):414-429. . View in PubMed

Gene-environment interaction in genome-wide association studies Am J Epidemiol. 2009 Jan 15; 169(2):219-26. . View in PubMed

Detecting gene-environment interactions in genome-wide association data Genet Epidemiol. 2009; 33 Suppl 1:S68-73. . View in PubMed

Hierarchical Bayes prioritization of marker associations from a genome-wide association scan for further investigation Genet Epidemiol. 2007 Dec; 31(8):871-82. . View in PubMed

Confidence intervals for multinomial logistic regression in sparse data Stat Med. 2007 Feb 20; 26(4):903-18. . View in PubMed

Validity, efficiency, and robustness of a family-based test of association Genet Epidemiol. 2006 Jan; 30(1):62-76. . View in PubMed

Comparison of family-based association tests in chromosome regions selected by linkage-based confidence intervals BMC Genet. 2005 Dec 30; 6 Suppl 1:S62. . View in PubMed

Does simultaneous consideration of multiple regions improve disease gene localization? Genet Epidemiol. 2001; 21 Suppl 1:S504-9.. View in PubMed

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