Karen Christine Johnson, PhD, CCC-A

Clinical Professor of Otolaryngology - Head and Neck Surgery (Clinician Educator) (Part-Time)

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Overview

Dr. Karen Johnson, Ph.D., CCC-A, is a Clinical Professor of Otolaryngology – Head and Neck Surgery (Clinician Educator, Part-Time) at the Keck School of Medicine of USC. She is a licensed audiologist with extensive expertise in pediatric hearing loss, cochlear implants, and early intervention strategies for children who are deaf or hard of hearing.At USC, Dr. Johnson teaches several graduate-level courses, including OHNS 402: The Dynamic Profession of Audiology, OHNS 503: Research Methods in Communication Sciences and Disorders, and OHNS 511: Aural (Re)habilitation. Her research interests focus on early childhood language and literacy development, particularly in children with hearing impairments.Dr. Johnson is the principal investigator of the “Come Read with Me” program, an innovative, grant-funded summer intervention aimed at enhancing literacy skills among deaf and hard-of-hearing children from bilingual (Spanish-English) homes. The program also provides training for parents and educators to support children’s reading and writing development. Her scholarly work includes numerous publications on pediatric audiology, cognitive outcomes in children with hearing loss, and the impact of early hearing interventions. Dr. Johnson has also led several NIH-funded studies on topics such as smoking cessation, cardiovascular risk, and diabetes management. #CoursesOHNS 402, The Dynamic Profession of Audiology (Spring Semester)OHNS 503, Research Methods in Communication Sciences and Disorders (Y1, Fall Semester)OHNS 505, Audiology for Speech-Language Pathologists (Y1, Spring Semester)OHNS 511, Aural (Re)habilitation (Y1, Summer Semester)OHNS 518, Research/Capstone (Y2, Fall and Spring Semesters)

Courses Taught

    OHNS 402, The Dynamic Profession of Audiology (Spring Semester)
    OHNS 503, Research Methods in Communication Sciences and Disorders (Y1, Fall Semester)
    OHNS 505, Audiology for Speech-Language Pathologists (Y1, Spring Semester)
    OHNS 511, Aural (Re)habilitation (Y1, Summer Semester)
    OHNS 518, Research/Capstone (Y2, Fall and Spring Semesters)

Publications

  • Sex Hormones Mediate Intensive Lifestyle Intervention-Induced Bone Mineral Density Changes: Look AHEAD Sex Hormone Study. J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e560-e568.. View in PubMed
  • Menopausal Hormone Therapy and Cardiovascular Diseases in Women With Vasomotor Symptoms: A Secondary Analysis of the Women’s Health Initiative Randomized Clinical Trials. JAMA Intern Med. 2025 Nov 01; 185(11):1330-1339.. View in PubMed
  • Risk of heart failure and subtypes with biomarker-calibrated protein intake: Women’s health initiative cohort study. Am J Prev Cardiol. 2025 Sep; 23:101051.. View in PubMed
  • Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation. J Gerontol A Biol Sci Med Sci. 2025 Jun 10; 80(7).. View in PubMed
  • Identifying Younger Postmenopausal Women With Osteoporosis Using USPSTF-Recommended Osteoporosis Risk Assessment Tools. JAMA Netw Open. 2025 03 03; 8(3):e250626.. View in PubMed
  • Epigenetic entropy, social disparity, and health and lifespan in the Women’s Health Initiative. medRxiv. 2025 Feb 26.. View in PubMed
  • Alzheimer Disease Blood Biomarkers and Cognition Among Individuals With Diabetes and Overweight or Obesity. JAMA Netw Open. 2025 02 03; 8(2):e2458149.. View in PubMed
  • Proton Pump Inhibitor Use and Incident Cardiovascular Disease in Older Postmenopausal Women. J Am Geriatr Soc. 2025 Feb; 73(2):411-421.. View in PubMed
  • Dietary Intervention Favorably Influences Physical Functioning: The Women’s Health Initiative Randomized Dietary Modification Trial. J Acad Nutr Diet. 2024 Nov; 124(11):1409-1418.e6.. View in PubMed
  • Estrogen Plus Progestin and Colorectal Cancer: Long-Term Findings From the Women’s Health Initiative Randomized Clinical Trial. J Clin Oncol. 2024 Oct 20; 42(30):3530-3536.. View in PubMed
  • Association of Lifestyle Intervention With Risk for Cardiovascular Events Differs by Level of Glycated Hemoglobin. J Clin Endocrinol Metab. 2024 Feb 20; 109(3):e1012-e1019.. View in PubMed
  • Menopausal hormone therapy and change in physical activity in the Women’s Health Initiative hormone therapy clinical trials. Menopause. 2023 09 01; 30(9):898-905.. View in PubMed
  • The long-term effect of intentional weight loss on changes in bone mineral density in persons with type 2 diabetes: results from the Look AHEAD randomized trial. Arch Osteoporos. 2023 07 14; 18(1):97.. View in PubMed
  • Race and Ethnicity and Fracture Prediction Among Younger Postmenopausal Women in the Women’s Health Initiative Study. JAMA Intern Med. 2023 07 01; 183(7):696-704.. View in PubMed
  • Healthy Lifestyle Index and Risk of Cardiovascular Disease Among Postmenopausal Women With Normal Body Mass Index. J Am Heart Assoc. 2023 06 20; 12(12):e029111.. View in PubMed
  • Association of Type 2 Diabetes Subgroups With Cognitive Status Without Modification From Lifestyle Intervention. J Clin Endocrinol Metab. 2023 05 17; 108(6):e334-e342.. View in PubMed
  • Association of tea-drinking habits with the risk of non-Hodgkin lymphoma: a prospective cohort study among postmenopausal women. Br J Nutr. 2023 May 14; 129(9):1543-1551.. View in PubMed
  • Home Literacy Experiences and Shared Reading Practices: Preschoolers With Hearing Loss. J Deaf Stud Deaf Educ. 2023 03 24; 28(2):189-200.. View in PubMed
  • Changes in Dietary Intake of Methionine, Folate/Folic Acid and Vitamin B12 and Survival in Postmenopausal Women with Breast Cancer: A Prospective Cohort Study. Nutrients. 2022 Nov 10; 14(22).. View in PubMed
  • Intensive Versus Standard Blood Pressure Lowering and Days Free of Cardiovascular Events and Serious Adverse Events: a Post Hoc Analysis of Systolic Blood Pressure Intervention Trial. J Gen Intern Med. 2022 11; 37(15):3797-3804.. View in PubMed
  • Correction to: Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study-a randomized trial in persons with prediabetes. Eur J Clin Nutr. 2022 Oct; 76(10):1491.. View in PubMed
  • Low Diastolic Blood Pressure and Mortality in Older Women. Results From the Women’s Health Initiative Long Life Study. Am J Hypertens. 2022 09 01; 35(9):795-802.. View in PubMed
  • Associations between cognitive function and endogenous levels of estradiol and testosterone in adults with type 2 diabetes. J Diabetes Complications. 2022 09; 36(9):108268.. View in PubMed
  • No Association Observed between Coffee Intake and Risk of Non-Hodgkin Lymphoma among Postmenopausal Women. J Acad Nutr Diet. 2022 09; 122(9):1725-1736.. View in PubMed
  • Safety and tolerability of high-dose daily vitamin D3 supplementation in the vitamin D and type 2 diabetes (D2d) study-a randomized trial in persons with prediabetes. Eur J Clin Nutr. 2022 08; 76(8):1117-1124.. View in PubMed
  • Impact of COVID-19 on life experiences reported by a diverse cohort of older adults with diabetes and obesity. Obesity (Silver Spring). 2022 06; 30(6):1268-1278.. View in PubMed
  • Incidence and Outcomes of Acute Heart Failure With Preserved Versus Reduced Ejection Fraction in SPRINT. Circ Heart Fail. 2021 12; 14(12):e008322.. View in PubMed
  • Developmental Outcomes in Early-Identified Children Who Are Hard of Hearing at 2 to 3 Years of Age. Ear Hear. 2021 Sep/Oct; 42(5):1238-1252.. View in PubMed
  • Risk of Subsequent Fractures in Postmenopausal Women After Nontraumatic vs Traumatic Fractures. JAMA Intern Med. 2021 08 01; 181(8):1055-1063.. View in PubMed
  • Changes in mood and health-related quality of life in Look AHEAD 6 years after termination of the lifestyle intervention. Obesity (Silver Spring). 2021 08; 29(8):1294-1308.. View in PubMed
  • After the initial fracture in postmenopausal women, where do subsequent fractures occur? EClinicalMedicine. 2021 May; 35:100826.. View in PubMed
  • Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Am J Hum Genet. 2021 04 01; 108(4):564-582.. View in PubMed
  • Within-Trial Cost-Effectiveness of a Structured Lifestyle Intervention in Adults With Overweight/Obesity and Type 2 Diabetes: Results From the Action for Health in Diabetes (Look AHEAD) Study. Diabetes Care. 2021 01; 44(1):67-74.. View in PubMed
  • Legacy of a 10-Year Multidomain Lifestyle Intervention on the Cognitive Trajectories of Individuals with Overweight/Obesity and Type 2 Diabetes Mellitus. Dement Geriatr Cogn Disord. 2021; 50(3):237-249.. View in PubMed
  • Long-term Change in Physiological Markers and Cognitive Performance in Type 2 Diabetes: The Look AHEAD Study. J Clin Endocrinol Metab. 2020 12 01; 105(12).. View in PubMed
  • Association of Sedentary Time and Incident Heart Failure Hospitalization in Postmenopausal Women. Circ Heart Fail. 2020 12; 13(12):e007508.. View in PubMed
  • The Association of Dietary Choline and Betaine With the Risk of Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care. 2020 11; 43(11):2840-2846.. View in PubMed
  • Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial. Lancet Neurol. 2020 11; 19(11):899-907.. View in PubMed
  • Barriers to eating are associated with poor physical function in older women. Prev Med. 2020 10; 139:106234.. View in PubMed
  • The Association of Methotrexate, Sulfasalazine, and Hydroxychloroquine Use With Fracture in Postmenopausal Women With Rheumatoid Arthritis: Findings From the Women’s Health Initiative. JBMR Plus. 2020 Oct; 4(10):e10393.. View in PubMed
  • Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial. Obesity (Silver Spring). 2020 09; 28(9):1678-1686.. View in PubMed
  • Associations of Number of Daily Eating Occasions with Type 2 Diabetes Risk in the Women’s Health Initiative Dietary Modification Trial. Curr Dev Nutr. 2020 Aug; 4(8):nzaa126.. View in PubMed
  • Social Support, Social Network Size, Social Strain, Stressful Life Events, and Coronary Heart Disease in Women With Type 2 Diabetes: A Cohort Study Based on the Women’s Health Initiative. Diabetes Care. 2020 08; 43(8):1759-1766.. View in PubMed
  • Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-term Follow-up of the Women’s Health Initiative Randomized Clinical Trials. JAMA. 2020 07 28; 324(4):369-380.. View in PubMed
  • Weight Change 2 Years After Termination of the Intensive Lifestyle Intervention in the Look AHEAD Study. Obesity (Silver Spring). 2020 05; 28(5):893-901.. View in PubMed
  • Relationship Between Dietary Magnesium Intake and Incident Heart Failure Among Older Women: The WHI. J Am Heart Assoc. 2020 04 07; 9(7):e013570.. View in PubMed
  • Intensive vs Standard Blood Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the Systolic Blood Pressure Intervention Trial. J Am Geriatr Soc. 2020 03; 68(3):496-504.. View in PubMed
  • Implications of the Hemoglobin Glycation Index on the Diagnosis of Prediabetes and Diabetes. J Clin Endocrinol Metab. 2020 03 01; 105(3).. View in PubMed
  • History of Cardiovascular Disease, Intensive Lifestyle Intervention, and Cardiovascular Outcomes in the Look AHEAD Trial. Obesity (Silver Spring). 2020 02; 28(2):247-258.. View in PubMed
  • Abnormal Exercise Test or CVD History on Weight Loss or Fitness: the Look AHEAD Trial. Transl J Am Coll Sports Med. 2020; 5(12).. View in PubMed
  • Low-Fat Dietary Pattern among Postmenopausal Women Influences Long-Term Cancer, Cardiovascular Disease, and Diabetes Outcomes. J Nutr. 2019 09 01; 149(9):1565-1574.. View in PubMed
  • Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions. JAMA. 2019 08 13; 322(6):524-534.. View in PubMed
  • Effect of Intensive and Standard Clinic-Based Hypertension Management on the Concordance Between Clinic and Ambulatory Blood Pressure and Blood Pressure Variability in SPRINT. J Am Heart Assoc. 2019 07 16; 8(14):e011706.. View in PubMed
  • Impact of Body Weight Dynamics Following Intentional Weight Loss on Fracture Risk: Results from The Action for Health in Diabetes Study. JBMR Plus. 2019 May; 3(5):e10086.. View in PubMed
  • Lipoprotein(a) plasma levels, bone mineral density and risk of hip fracture: a post hoc analysis of the Women’s Health Initiative, USA. BMJ Open. 2019 04 24; 9(4):e027257.. View in PubMed
  • End-of-Trial Health Outcomes in Look AHEAD Participants who Elected to have Bariatric Surgery. Obesity (Silver Spring). 2019 04; 27(4):581-590.. View in PubMed
  • Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial. JAMA. 2019 02 12; 321(6):553-561.. View in PubMed
  • Persistent vasomotor symptoms and breast cancer in the Women’s Health Initiative. Menopause. 2018 12 28; 26(6):578-587.. View in PubMed
  • Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1560-1567.. View in PubMed
  • The association of sleep duration and quality with all-cause and cause-specific mortality in the Women’s Health Initiative. Sleep Med. 2018 10; 50:48-54.. View in PubMed
  • Sex-related differences in the prevalence of cognitive impairment among overweight and obese adults with type 2 diabetes. Alzheimers Dement. 2018 09; 14(9):1184-1192.. View in PubMed
  • Risk Factor Burden, Heart Failure, and Survival in Women of Different Ethnic Groups: Insights From the Women’s Health Initiative. Circ Heart Fail. 2018 05; 11(5):e004642.. View in PubMed
  • Syncope, Hypotension, and Falls in the Treatment of Hypertension: Results from the Randomized Clinical Systolic Blood Pressure Intervention Trial. J Am Geriatr Soc. 2018 04; 66(4):679-686.. View in PubMed
  • Cochlear Implants Int, 15-16. Parent engagement in pediatric CI outcomes: Parents as partners. 2018; (15-16).
  • Effects of Intensive BP Control in CKD. J Am Soc Nephrol. 2017 Sep; 28(9):2812-2823.. View in PubMed
  • A Longitudinal Investigation of the Home Literacy Environment and Shared Book Reading in Young Children With Hearing Loss. Ear Hear. 2017 Jul/Aug; 38(4):441-454.. View in PubMed
  • Sentence Recognition in Quiet and Noise by Pediatric Cochlear Implant Users: Relationships to Spoken Language. Otol Neurotol. 2016 Feb; 37(2):e75-81.. View in PubMed
  • Estrogen and colorectal cancer incidence and mortality. Cancer. 2015 Sep 15; 121(18):3261-71.. View in PubMed
  • A Prospective Longitudinal Study of U.S. Children Unable to Achieve Open-Set Speech Recognition 5 Years After Cochlear Implantation. Otol Neurotol. 2015 Jul; 36(6):985-92.. View in PubMed
  • Developmental outcomes of early-identified children who are hard of hearing at 12 to 18 months of age. Early Hum Dev. 2015 Jan; 91(1):47-55.. View in PubMed
  • Studies in pediatric hearing loss at the House Research Institute. J Am Acad Audiol. 2012 Jun; 23(6):412-21.. View in PubMed
  • Assessing joint attention and symbolic play in children with cochlear implants and multiple disabilities: two case studies. Otol Neurotol. 2008 Feb; 29(2):246-50.. View in PubMed
  • Comprehensive evaluation of a child with an auditory brainstem implant. Otol Neurotol. 2008 Feb; 29(2):251-7.. View in PubMed
  • Tracking development of speech recognition: longitudinal data from hierarchical assessments in the Childhood Development after Cochlear Implantation Study. Otol Neurotol. 2008 Feb; 29(2):240-5.. View in PubMed
  • Childhood Development after Cochlear Implantation (CDaCI) study: design and baseline characteristics. Cochlear Implants Int. 2007 Jun; 8(2):92-116.. View in PubMed
  • Speech recognition at 1-year follow-up in the childhood development after cochlear implantation study: Methods and preliminary findings. Audiol Neurootol. 2006; 11(4):259-68.. View in PubMed
  • Audiologic assessment of children with suspected hearing loss. Otolaryngol Clin North Am. 2002 Aug; 35(4):711-32.. View in PubMed
  • Central auditory processing disorder: a case study. J Am Acad Audiol. 1991 Jan; 2(1):36-54.. View in PubMed
  • Pediatric central auditory dysfunction. Comparison of children with confirmed lesions versus suspected processing disorders. Am J Otol. 1988 Dec; 9 Suppl:63-71.. View in PubMed
  • Interactions of age, gender, and sensorineural hearing loss on ABR latency. Ear Hear. 1988 Aug; 9(4):168-76.. View in PubMed
  • Effect of response criterion on measures of speech understanding in the elderly. Ear Hear. 1988 Apr; 9(2):49-56.. View in PubMed