Karen Christine Johnson, PhD, CCC-A

Clinical Professor of Otolaryngology - Head and Neck Surgery (Clinician Educator) (Part-Time)

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Overview

Dr. Karen Johnson, Ph.D., CCC-A, is a Clinical Professor of Otolaryngology – Head and Neck Surgery (Clinician Educator, Part-Time) at the Keck School of Medicine of USC. She is a licensed audiologist with extensive expertise in pediatric hearing loss, cochlear implants, and early intervention strategies for children who are deaf or hard of hearing.

At USC, Dr. Johnson teaches several graduate-level courses, including OHNS 402: The Dynamic Profession of Audiology, OHNS 503: Research Methods in Communication Sciences and Disorders, and OHNS 511: Aural (Re)habilitation. Her research interests focus on early childhood language and literacy development, particularly in children with hearing impairments.

Dr. Johnson is the principal investigator of the “Come Read with Me” program, an innovative, grant-funded summer intervention aimed at enhancing literacy skills among deaf and hard-of-hearing children from bilingual (Spanish-English) homes. The program also provides training for parents and educators to support children’s reading and writing development.

Her scholarly work includes numerous publications on pediatric audiology, cognitive outcomes in children with hearing loss, and the impact of early hearing interventions. Dr. Johnson has also led several NIH-funded studies on topics such as smoking cessation, cardiovascular risk, and diabetes management.

#Courses

OHNS 402, The Dynamic Profession of Audiology (Spring Semester)
OHNS 503, Research Methods in Communication Sciences and Disorders (Y1, Fall Semester)
OHNS 505, Audiology for Speech-Language Pathologists (Y1, Spring Semester)
OHNS 511, Aural (Re)habilitation (Y1, Summer Semester)
OHNS 518, Research/Capstone (Y2, Fall and Spring Semesters)

Research Funding

  • Managing Obesity by Leveraging Health Information Technology to Lower Cancer Risk
    NIH · R01CA267643 · Jan 14, 2022 – Dec 31, 2026 · Role: Principal Investigator
  • Intensive Lifestyle Intervention, Metabolomics, and Risk of Frailty Fracture in Overweight or Obese Patients with Type 2 Diabetes
    NIH · R01AG068232 · Sep 30, 2021 – May 31, 2026 · Role: Co-Principal Investigator
  • Targeted Approaches to Weight Control for Young Adults Grant with RCU Proposal
    NIH · U01HL096628 · Aug 17, 2009 – May 31, 2015 · Role: Principal Investigator
  • A Clinical Trial of Two Medications on Smoking Cessation
    NIH · R01HL066025 · Jan 7, 2002 – Dec 31, 2007 · Role: Principal Investigator
  • The Use of Sibutramine in Smoking Cessation
    NIH · R01HL068049 · Sep 1, 2001 – Aug 31, 2008 · Role: Principal Investigator
  • 07/16 Action for Health in Diabetes Extension Study Research Project
    NIH · U01DK057078 · Sep 30, 1999 – Jan 31, 2021 · Role: Principal Investigator
  • TREATING NICOTINE ADDICTION IN PREGNANCY
    NIH · R01DA010527 · Sep 29, 1997 – Aug 31, 2001 · Role: Principal Investigator
  • NORPLANT EFFECT ON CARDIOVASCULAR RISK IN YOUNG WOMEN
    NIH · R01HD029478 · May 1, 1994 – Apr 30, 1999 · Role: Principal Investigator
  • VANGUARD CENTER FOR WOMEN'S HEALTH INITIATIVE
    NIH/WHI · N01WH032118 · Apr 13, 1993 – Sep 14, 2005 · Role: Principal Investigator

Publications

  • Epigenetic entropy, socioeconomic differences, and health and lifespan in the Women’s Health Initiative. Clin Epigenetics. 2026 Jun 19.. View in PubMed
  • Low-fat dietary pattern and dementia mortality: a secondary analysis of the Women’s Health Initiative dietary modification randomized clinical trial with long-term follow-up. Menopause. 2026 Jun 09.. View in PubMed
  • Weight loss lifestyle intervention and bone health hormonal markers in type 2 diabetes: analysis from look AHEAD study. J Endocr Soc. 2026 May; 10(5):bvag089.. View in PubMed
  • Sex Hormones Mediate Intensive Lifestyle Intervention-Induced Bone Mineral Density Changes: Look AHEAD Sex Hormone Study. J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e560-e568.. View in PubMed
  • Longitudinal transitions in sedentary behavior and physical activity in relation to all-cause and cause-specific mortality among postmenopausal women. Geroscience. 2026 Aug; 48(4):5827-5842.. View in PubMed
  • Menopausal Hormone Therapy and Cardiovascular Diseases in Women With Vasomotor Symptoms: A Secondary Analysis of the Women’s Health Initiative Randomized Clinical Trials. JAMA Intern Med. 2025 11 01; 185(11):1330-1339.. View in PubMed
  • Risk of heart failure and subtypes with biomarker-calibrated protein intake: Women’s health initiative cohort study. Am J Prev Cardiol. 2025 Sep; 23:101051.. View in PubMed
  • Comparative Effectiveness of Metformin Versus Sulfonylureas on Exceptional Longevity in Women With Type 2 Diabetes: Target Trial Emulation. J Gerontol A Biol Sci Med Sci. 2025 06 10; 80(7).. View in PubMed
  • A Systematic Review of Needleless Connector Function and Occlusion Outcomes: Evidence Leading the Way. J Infus Nurs. 2025 Mar-Apr 01; 48(2):84-105.. View in PubMed
  • Identifying Younger Postmenopausal Women With Osteoporosis Using USPSTF-Recommended Osteoporosis Risk Assessment Tools. JAMA Netw Open. 2025 03 03; 8(3):e250626.. View in PubMed