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Karrune Woan

Assistant Professor of Clinical Medicine

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Email [email protected]
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Publications

  • A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. J Immunol. 2014 Sep 15; 193(6):2850-62.. View in PubMed
  • Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells. Mol Immunol. 2014 Jul; 60(1):44-53.. View in PubMed
  • The antimelanoma activity of the histone deacetylase inhibitor panobinostat (LBH589) is mediated by direct tumor cytotoxicity and increased tumor immunogenicity. Melanoma Res. 2013 Oct; 23(5):341-8.. View in PubMed
  • Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth. J Med Chem. 2012 Nov 26; 55(22):9891-9.. View in PubMed
  • Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity. Cancer Res. 2012 Sep 01; 72(17):4440-8.. View in PubMed
  • Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer. Immunol Cell Biol. 2012 Jan; 90(1):55-65.. View in PubMed
  • Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10. J Immunol. 2011 Apr 01; 186(7):3986-96.. View in PubMed
  • A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin Cancer Res. 2010 Sep 15; 16(18):4583-94.. View in PubMed
  • Potential therapeutic role of natural killer cells in cancer. Expert Opin Biol Ther. 2007 Jan; 7(1):17-29.. View in PubMed

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