Kathleen Alanna Page, MD

Associate Professor of Medicine

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Overview

Dr. Kathleen “Katie” Page is a physician specializing in diabetes and childhood obesity at the Keck School of Medicine of the University of Southern California (USC). She is Co-Chief of the Division of Endocrinology & Diabetes, Director of the Diabetes and Obesity Research Institute, Co-Director of Research Development at the Southern California Clinical and Translational Science Institute, Co-Director of the Investigator Development Core at the Southern California Center for Latino Health, Associate Professor of Medicine (with Tenure), and a practicing Endocrinologist in the Department of Medicine at USC.

Dr. Page has an active research program that seeks to understand the causes of obesity and diabetes so that more effective strategies can be developed for reducing the number of people affected by these health conditions. Her research has been recognized by awards from the Endocrine Society, the American Heart Association, the American Diabetes Association, and the American Federation for Medical Research. She has received grant funding from the National Institutes of Health (NIH), the American Diabetes Association, the American Heart Association and the Doris Duke Charitable Foundation.

Awards

  • American Heart Association : Mark Bieber Outstanding Research Award, 2014
  • American Diabetes Association : Pathway to Stop Diabetes Accelerator Award, 2013-2018
  • Endocrine Society: Outstanding Early Investigator Award, 2012
  • Endocrine Society & Amgen: Early Investigator Award, 2012
  • Western American Federation of Medical Research: Outstanding Young Investigator Award, 2012
  • Genentech: Endocrine Fellows Travel Award Recipient, 2008
  • National Institutes of Health: Clinical Research Loan Repayment Program Award Recipient, 2007-2014
  • Keck School of Medicine of USC: Dean’s Scholar Award, 2002

Publications

  • Maternal obesity and diabetes during pregnancy and early autism screening score at well-child visits in standard clinical practice Autism. 2024 Apr; 28(4):975-984. . View in PubMed
  • Exposure to gestational diabetes mellitus in utero impacts hippocampal functional connectivity in response to food cues in children Res Sq. 2024 Mar 12. . View in PubMed
  • Associations between affect dynamics and eating regulation in daily life: a preliminary ecological momentary assessment study Cogn Emot. 2024 Mar 01; 1-7. . View in PubMed
  • Influence of insulin sensitivity on food cue evoked functional brain connectivity in children bioRxiv. 2024 Feb 15. . View in PubMed
  • Types of diabetes during pregnancy and risk of depression and anxiety in offspring from childhood to young adulthood Diabetes Obes Metab. 2024 Jan; 26(1):224-232. . View in PubMed
  • Prenatal Exposure to Gestational Diabetes Mellitus is Associated with Mental Health Outcomes and Physical Activity has a Modifying Role Res Sq. 2023 Aug 29. . View in PubMed
  • Associations among prenatal exposure to gestational diabetes mellitus, brain structure, and child adiposity markers Obesity (Silver Spring). 2023 11; 31(11):2699-2708. . View in PubMed
  • Sweet taste preference is associated with greater hypothalamic response to glucose and longitudinal weight gain Physiol Behav. 2023 10 15; 270:114292. . View in PubMed
  • Relationships between physical activity, healthy eating and cortical thickness in children and young adults Brain Imaging Behav. 2022 Dec; 16(6):2690-2704. . View in PubMed
  • Glucose variability: A physiological correlate of eating disorder behaviors among individuals with binge-spectrum eating disorders Int J Eat Disord. 2022 Oct 28. . View in PubMed
  • Associations Between Sleep and Metabolic Outcomes in Preadolescent Children J Endocr Soc. 2022 Oct 11; 6(11):bvac137. . View in PubMed
  • A gut reaction: Microbiome-driven glycemic effects of non-nutritive sweeteners Cell. 2022 Sep 01; 185(18):3282-3284. . View in PubMed
  • Time-Varying Associations Between Device-Based and Ecological Momentary Assessment-Reported Sedentary Behaviors and the Concurrent Affective States Among Adolescents: Proof-of-Concept Study JMIR Form Res. 2022 Jun 10; 6(6):e37743. . View in PubMed
  • FGF21 response to sucrose is associated with BMI and dorsal striatal signaling in humans Obesity (Silver Spring). 2022 06; 30(6):1239-1247. . View in PubMed
  • Exposure to Gestational Diabetes Mellitus Prior to 26 Weeks Is Related to the Presence of Mediobasal Hypothalamic Gliosis in Children Diabetes. 2022 12 01; 71(12):2552-2556. . View in PubMed
  • Patterns of Objectively Measured Sedentary Time and Emotional Disorder Symptoms Among Youth J Pediatr Psychol. 2022 07 19; 47(7):757-768. . View in PubMed
  • The role of maternal BMI on brain food cue reactivity in children: a preliminary study Brain Imaging Behav. 2021 Dec; 15(6):2746-2755. . View in PubMed
  • ErratumAssociations Between Exposure to Gestational Diabetes Mellitus In Utero and Daily Energy Intake, Brain Responses to Food Cues, and Adiposity in Children. Diabetes Care 2021;44:1185-1193. Diabetes Care. 2021 Jul 28. . View in PubMed
  • Prenatal exposure to gestational diabetes is associated with anxiety and physical inactivity in children during COVID-19 Clin Obes. 2021 Feb; 11(1):e12422. . View in PubMed
  • Brain responses to glucose ingestion are greater in children than adults and are associated with overweight and obesity Obesity (Silver Spring). 2021 12; 29(12):2081-2088. . View in PubMed
  • BMI status and associations between affect, physical activity and anxiety among US. children during COVID-19. Pediatr Obes. 2021 09; 16(9):e12786. . View in PubMed
  • Child physical activity as a modifier of the relationship between prenatal exposure to maternal overweight/obesity and neurocognitive outcomes in offspring Int J Obes (Lond). 2021 06; 45(6):1310-1320. . View in PubMed
  • Associations Between Exposure to Gestational Diabetes Mellitus In Utero and Daily Energy Intake, Brain Responses to Food Cues, and Adiposity in Children Diabetes Care. 2021 05; 44(5):1185-1193. . View in PubMed
  • Evidence of a Role for the Hippocampus in Food-Cue Processing and the Association with Body Weight and Dietary Added Sugar Obesity (Silver Spring). 2021 02; 29(2):370-378. . View in PubMed
  • The effect of body mass index on hippocampal morphology and memory performance in late childhood and adolescence Hippocampus. 2021 02; 31(2):189-200. . View in PubMed
  • Selective morphological and volumetric alterations in the hippocampus of children exposed in utero to gestational diabetes mellitus Hum Brain Mapp. 2021 06 01; 42(8):2583-2592. . View in PubMed
  • Obesity and Sex-Related Associations With Differential Effects of Sucralose vs Sucrose on Appetite and Reward Processing: A Randomized Crossover Trial JAMA Netw Open. 2021 09 01; 4(9):e2126313. . View in PubMed
  • Appetite-Regulating Hormones Are Reduced After Oral Sucrose vs Glucose: Influence of Obesity, Insulin Resistance, and Sex J Clin Endocrinol Metab. 2021 03 08; 106(3):654-664. . View in PubMed
  • Obesity and Dietary Added Sugar Interact to Affect Postprandial GLP-1 and Its Relationship to Striatal Responses to Food Cues and Feeding Behavior Front Endocrinol (Lausanne). 2021; 12:638504. . View in PubMed
  • Impacts of Acute Sucralose and Glucose on Brain Activity during Food Decisions in Humans Nutrients. 2020 Oct 27; 12(11). . View in PubMed
  • Associations between Affect, Physical Activity, and Anxiety Among US Children During COVID-19 medRxiv. 2020 Oct 23. . View in PubMed
  • Children’s Anxiety and Physical Activity during COVID-19 in Relation to Prenatal Exposure to Gestational Diabetes medRxiv. 2020 Aug 07. . View in PubMed
  • Dietary Fructose Intake and Hippocampal Structure and Connectivity during Childhood Nutrients. 2020 Mar 26; 12(4). . View in PubMed
  • Effects of Non-nutritive Sweeteners on Sweet Taste Processing and Neuroendocrine Regulation of Eating Behavior Curr Nutr Rep. 2020 09; 9(3):278-289. . View in PubMed
  • Interstitial glucose and subsequent affective and physical feeling states: A pilot study combining continuous glucose monitoring and ecological momentary assessment in adolescents J Psychosom Res. 2020 08; 135:110141. . View in PubMed
  • Fasting may increase incentive signaling for nonfood rewards Nutr Res. 2020 05; 77:43-53. . View in PubMed
  • Sex differences in the association between prenatal exposure to maternal obesity and hippocampal volume in children Brain Behav. 2020 02; 10(2):e01522. . View in PubMed
  • Contributions of Prenatal Exposures and Child Lifestyle to Insulin Sensitivity J Clin Endocrinol Metab. 2020 07 01; 105(7). . View in PubMed
  • Hemoglobin A1c Levels During Pregnancy and Risk of Autism Spectrum Disorders in Offspring JAMA. 2019 Aug 06; 322(5):460-461. . View in PubMed
  • Children Exposed to Maternal Obesity or Gestational Diabetes Mellitus During Early Fetal Development Have Hypothalamic Alterations That Predict Future Weight Gain Diabetes Care. 2019 08; 42(8):1473-1480. . View in PubMed
  • Effects of Physical Activity and Sedentary Behavior on Brain Response to High-Calorie Food Cues in Young Adults Obesity (Silver Spring). 2018 Mar; 26(3):540-546. . View in PubMed
  • Maternal Gestational Diabetes Mellitus, Type 1 Diabetes, and Type 2 Diabetes During Pregnancy and Risk of ADHD in Offspring Diabetes Care. 2018 12; 41(12):2502-2508. . View in PubMed
  • Maternal Type 1 Diabetes and Risk of Autism in Offspring JAMA. 2018 07 03; 320(1):89-91. . View in PubMed
  • Influences of Dietary Added Sugar Consumption on Striatal Food-Cue Reactivity and Postprandial GLP-1 Response Front Psychiatry. 2017; 8:297. . View in PubMed
  • Resting state hypothalamic response to glucose predicts glucose-induced attenuation in the ventral striatal response to food cues Appetite. 2017 09 01; 116:464-470. . View in PubMed
  • The Effect of Depo Medroxyprogesterone Acetate (DMPA) on Cerebral Food Motivation Centers: A Pilot Study using Functional Magnetic Resonance Imaging Contraception. 2016 10; 94(4):321-7. . View in PubMed
  • Differential effects of fructose versus glucose on brain and appetitive responses to food cues and decisions for food rewards Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6509-14. . View in PubMed
  • Association of maternal diabetes with autism in offspring JAMA. 2015 Apr 14; 313(14):1425-34. . View in PubMed
  • Behavioral contributions to the pathogenesis of type 2 diabetes Curr Diab Rep. 2014 Apr; 14(4):475. . View in PubMed
  • Gestational diabetes mellitus, maternal obesity, and adiposity in offspring J Pediatr. 2014 Apr; 164(4):807-10. . View in PubMed
  • Abdominal fat is associated with a greater brain reward response to high-calorie food cues in Hispanic women Obesity (Silver Spring). 2013 Oct; 21(10):2029-36. . View in PubMed
  • Increased brain transport and metabolism of acetate in hypoglycemia unawareness J Clin Endocrinol Metab. 2013 Sep; 98(9):3811-20. . View in PubMed
  • Differential effects of fructose and glucose on cerebral blood flow–reply JAMA. 2013 May 01; 309(17):1769. . View in PubMed
  • Interventions to preserve beta-cell function in the management and prevention of type 2 diabetes Curr Diab Rep. 2013 Apr; 13(2):252-60. . View in PubMed
  • Effects of fructose vs glucose on regional cerebral blood flow in brain regions involved with appetite and reward pathways JAMA. 2013 Jan 02; 309(1):63-70. . View in PubMed
  • Effects of Fructose vs Glucose on Regional Cerebral Blood Flow in Brain Regions Involved With Appetite and Reward Pathways JAMA. 2013; 1(309):63-70. . View in PubMed
  • Gestational diabetes mellitus: risks and management during and after pregnancy Nat Rev Endocrinol. 2012 Nov; 8(11):639-49. . View in PubMed
  • BOLD response to semantic and syntactic processing during hypoglycemia is load-dependent Brain Lang. 2012 Jan; 120(1):1-14. . View in PubMed
  • Approach to the patient with gestational diabetes after delivery J Clin Endocrinol Metab. 2011 Dec; 96(12):3592-8. . View in PubMed
  • Circulating glucose levels modulate neural control of desire for high-calorie foods in humans J Clin Invest. 2011 Oct; 121(10):4161-9. . View in PubMed
  • The vicious cycle of maternal diabetes and obesity: moving from “what” to “how” and “why” J Pediatr. 2011 Jun; 158(6):872-3. . View in PubMed
  • Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia Diabetes. 2009 May; 58(5):1237-44. . View in PubMed
  • Small decrements in systemic glucose provoke increases in hypothalamic blood flow prior to the release of counterregulatory hormones Diabetes. 2009 Feb; 58(2):448-52. . View in PubMed
  • A patient with hypophosphatemia, a femoral fracture, and recurrent kidney stones: report of a novel mutation in SLC34A3 Endocr Pract. 2008 Oct; 14(7):869-74. . View in PubMed
  • Development of thyroid storm after surgical resection of a thyrotropin-secreting pituitary adenoma Endocr Pract. 2008 Sep; 14(6):732-7. . View in PubMed
  • A patient with type B insulin resistance syndrome, responsive to immune therapy Nat Clin Pract Endocrinol Metab. 2007 Dec; 3(12):835-40. . View in PubMed
  • Representative freshwater bacterioplankton isolated from Crater Lake, Oregon Appl Environ Microbiol. 2004 Nov; 70(11):6542-50. . View in PubMed