Laila Ingrid Muderspach, MD

Clinical Professor of Obstetrics & Gynecology (Part-Time)

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Overview

Dr. Muderspach has been committed to improving women’s health throughout her career. Her clinical expertise is in the diagnosis, medical and surgical treatment of gynecologic malignancies. She believes in treating the “whole person” with respect, compassion as well as access for all to state of the art medicine and surgery. Her training at USC and UCLA, along with her vast clinical experience, have given her the skills to teach and share her passion for caring for women to residents, fellows, and students. She has won numerous awards for her work teaching and caring for patients in Ob/Gyn. She is recognized in “Best Doctors” as selected by her peers.

Awards

  • LAC + USC: Women’s Choice Award, America’s Best Hospitals, Patient Safety, 2016
  • Los Angeles: Top Doctors, 2015-2016
  • Pasadena Magazine: Top Doctors, 2013-2015
  • Best Doctors, 2009-2014
  • The American College of Obstetricians and Gynecologists: National Faculty Award, 2007
  • CREOG: Teaching Award, 2006
  • Lester T. Hibbard : Faculty Teaching Award, 2004-2005
  • C.A.R.E.S. : Woman of the Year in Medicine, 2000
  • Association of Professors of Gynecology and Obstetrics: Excellent Teaching Award, 1998
  • American Cancer Society : Clinical Fellow, 1989-1990
  • American Medical Women’s Associatoin: Janet M. Glasgow Memorial Achievement Citation, 1985
  • Alpha Omega Alpha Honor Medical Society, 1984
  • Mackenzie Foundation Scholarship, 1983-1985

Publications

  • Prognostic performance of the 2023 FIGO staging schema for endometrial cancer Gynecol Oncol. 2024 May 06; 187:37-45. . View in PubMed
  • Benefits of the Enhanced Recovery After Surgery (ERAS) Pathway With Quadratus Lumborum Blocks for Minimally Invasive Gynecologic Surgery Patients: A Retrospective Cohort Study Cureus. 2023 Nov; 15(11):e49183. . View in PubMed
  • Temporal trends of failure-to-rescue following perioperative complications in vulvar cancer surgery in the United States Gynecol Oncol. 2023 Oct; 177:1-8. . View in PubMed
  • Two staged phase II clinical trial of Eribulin monotherapy in advanced or recurrent cervical cancer Gynecol Oncol. 2023 06; 173:49-57. . View in PubMed
  • Our Space of Morrow Int J Gynecol Cancer. 2022 Nov 21. . View in PubMed
  • Side-to-end reanastomosis after low-anterior resection (STELAR): Outcomes, feasibility, and description of procedure performed by a gynecologic oncology service J Surg Oncol. 2022 Sep; 126(3):563-570. . View in PubMed
  • Population-level uptake of neoadjuvant chemotherapy for stage IVB endometrial cancer Gynecol Oncol. 2022 06; 165(3):428-436. . View in PubMed
  • Sentinel lymph node biopsy for vulvar melanoma: trends in tumor stage-specific utilization Am J Obstet Gynecol. 2022 03; 226(3):438-440. . View in PubMed
  • Sentinel lymph node biopsy for stage II endometrial cancer: Recent utilization and outcome in the United States Gynecol Oncol. 2022 01; 164(1):46-52. . View in PubMed
  • Utilization and Outcomes of Sentinel Lymph Node Biopsy for Early Endometrial Cancer Obstet Gynecol. 2022 05 01; 139(5):809-820. . View in PubMed
  • Correction to: Adjuvant hysterectomy following primary chemoradiation for stage IB2 and IIA2 cervical cancer: a retrospective comparison of complications for open versus minimally invasive surgery Radiat Oncol. 2021 Aug 25; 16(1):162. . View in PubMed
  • Adjuvant hysterectomy following primary chemoradiation for stage IB2 and IIA2 cervical cancer: a retrospective comparison of complications for open versus minimally invasive surgery Radiat Oncol. 2021 Jun 29; 16(1):123. . View in PubMed
  • Implementation of multidisciplinary practice change to improve outcomes for women with placenta accreta spectrum Eur J Obstet Gynecol Reprod Biol. 2020 Mar; 246:194-196. . View in PubMed
  • Prolonged intubation after robotic-assisted hysterectomy for endometrial cancer: Case reports Gynecol Oncol Rep. 2018 Aug; 25:106-108. . View in PubMed
  • Successful resuscitation after cardiac arrest secondary to carboplatin infusion: A case report Gynecol Oncol Rep. 2018 Feb; 23:7-9. . View in PubMed
  • Incidence of urinary tract injury and utility of routine cystoscopy during total laparoscopic hysterectomy for endometrial cancer Eur J Obstet Gynecol Reprod Biol. 2017 Jun; 213:141-142. . View in PubMed
  • Intrauterine Device Use and Cervical Cancer Risk: A Systematic Review and Meta-analysis Obstet Gynecol. 2017 12; 130(6):1226-1236. . View in PubMed
  • Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer Obstet Gynecol. 2017 01; 129(1):139-151. . View in PubMed
  • Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer Menopause. 2016 Feb; 23(2):189-96. . View in PubMed
  • Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer Obstet Gynecol. 2016 10; 128(4):761-70. . View in PubMed
  • Weight Change Pattern and Survival Outcome of Women with Endometrial Cancer Ann Surg Oncol. 2016 09; 23(9):2988-97. . View in PubMed
  • Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C Clin Immunol. 2015 Dec; 161(2):197-208. . View in PubMed
  • Relative Morbidity and Mortality of Panniculectomy-Combined Surgical Staging in Endometrial Cancer Int J Gynecol Cancer. 2015 Oct; 25(8):1503-12. . View in PubMed
  • Lymph Node Micrometastases in Early-Stage Cervical Cancer are Not Predictive of Survival Int J Gynecol Pathol. 2015 Jul; 34(4):379-84. . View in PubMed
  • Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome Obstet Gynecol. 2015 Feb; 125(2):424-433. . View in PubMed
  • Significance of adenomyosis on tumor progression and survival outcome of endometrial cancer Ann Surg Oncol. 2014 Dec; 21(13):4246-55. . View in PubMed
  • Endometrial echo complex thickness in postmenopausal endometrial cancer Gynecol Oncol. 2013 Oct; 131(1):109-12. . View in PubMed
  • Predictive model of venous thromboembolism in endometrial cancer Gynecol Oncol. 2013 Mar; 128(3):544-51. . View in PubMed
  • Novel application of a fecal management system for vaginal use in radiotherapy-associated rectovaginal fistula Palliat Med. 2013 Jan; 27(1):91-3. . View in PubMed
  • Phase II study of gemcitabine and docetaxel in recurrent platinum resistant ovarian cancer Cancer Invest. 2012 May; 30(4):295-9. . View in PubMed
  • A low-fidelity total abdominal hysterectomy teaching model for obstetrics and gynecology residents Simul Healthc. 2012 Apr; 7(2):123-6. . View in PubMed
  • Psychosocial adjustment among low-income Latina cervical cancer patients J Psychosoc Oncol. 2011; 29(5):515-33. . View in PubMed
  • Cancer treatment adherence among low-income women with breast or gynecologic cancer: a randomized controlled trial of patient navigation Cancer. 2009 Oct 01; 115(19):4606-15. . View in PubMed
  • HER2 gene amplification and EGFR expression in a large cohort of surgically staged patients with nonendometrioid (type II) endometrial cancer Br J Cancer. 2009 Jan 13; 100(1):89-95. . View in PubMed
  • Impact of laparoscopic experience on performance on laparoscopic training drills among obstetrics and gynecology residents: a pilot study J Minim Invasive Gynecol. 2009 Jan-Feb; 16(1):72-5. . View in PubMed
  • High-grade cervical disease in adolescents with HIV J Low Genit Tract Dis. 2008 Jul; 12(3):199-203. . View in PubMed
  • Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093 Contraception. 2008 Feb; 77(2):84-90. . View in PubMed
  • Radiation therapy with or without weekly cisplatin for bulky stage 1B cervical carcinoma: follow-up of a Gynecologic Oncology Group trialAm J Obstet Gynecol. 2007 Nov; 197(5):503. e1-6. . View in PubMed
  • A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia Gynecol Oncol. 2007 Sep; 106(3):558-66. . View in PubMed
  • Therapeutic vaccination for HPV induced cervical cancers Dis Markers. 2007; 23(4):337-52. . View in PubMed
  • Feasibility of laparoscopic extraperitoneal surgical staging for locally advanced cervical carcinoma in a gynecologic oncology fellowship training program J Minim Invasive Gynecol. 2006 Sep-Oct; 13(5):391-7. . View in PubMed
  • A phase III randomized trial of postoperative pelvic irradiation in Stage IB cervical carcinoma with poor prognostic features: follow-up of a gynecologic oncology group study Int J Radiat Oncol Biol Phys. 2006 May 01; 65(1):169-76. . View in PubMed
  • Endometrial cancer patients have a significant risk of harboring isolated tumor cells in histologically negative lymph nodes Int J Gynecol Cancer. 2006 May-Jun; 16(3):1336-41. . View in PubMed
  • Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix Gynecol Oncol. 2006 Feb; 100(2):288-93. . View in PubMed
  • Digital camera assessment for detection of cervical intraepithelial neoplasia in rural El Salvador Int J Gynaecol Obstet. 2005 Oct; 91(1):42-6. . View in PubMed
  • Depression, correlates of depression, and receipt of depression care among low-income women with breast or gynecologic cancer J Clin Oncol. 2005 May 01; 23(13):3052-60. . View in PubMed
  • Phase I clinical trial of topotecan and pegylated liposomal doxorubicin Cancer Invest. 2005; 23(8):665-70. . View in PubMed
  • The impact of anti HPV vaccination on cervical cancer incidence and HPV induced cervical lesions: consequences for clinical management Eur J Gynaecol Oncol. 2005; 26(2):129-42. . View in PubMed
  • Identification of micrometastases in histologically negative lymph nodes of early-stage cervical cancer patients Obstet Gynecol. 2004 Jun; 103(6):1204-10. . View in PubMed
  • ZYC101a for treatment of high-grade cervical intraepithelial neoplasia: a randomized controlled trial Obstet Gynecol. 2004 Feb; 103(2):317-26. . View in PubMed
  • Immunotherapy of human cervical high-grade cervical intraepithelial neoplasia with microparticle-delivered human papillomavirus 16 E7 plasmid DNA Am J Obstet Gynecol. 2003 Apr; 188(4):916-26. . View in PubMed
  • Abnormal cervical screen follow-up among low-income Latinas: Project SAFe J Womens Health Gend Based Med. 2002 Sep; 11(7):639-51. . View in PubMed
  • The impact of HIV infection and immunodeficiency on human papillomavirus type 6 or 11 infection and on genital warts Sex Transm Dis. 2002 Aug; 29(8):427-35. . View in PubMed
  • The effect of highly active antiretroviral therapy on cervical cytologic changes associated with oncogenic HPV among HIV-infected women AIDS. 2001 Nov 09; 15(16):2157-64. . View in PubMed
  • Correlating Papanicolaou Smear, Colposcopic Impression, and Biopsy: Results from the Women’s Interagency HIV Study J Low Genit Tract Dis. 2001 Oct; 5(4):212-8. . View in PubMed
  • Evolution of cervical abnormalities among women with HIV-1: evidence from surveillance cytology in the women’s interagency HIV study J Acquir Immune Defic Syndr. 2001 Aug 15; 27(5):432-42. . View in PubMed
  • A Phase II study of topotecan in patients with squamous cell carcinoma of the cervix: a gynecologic oncology group study Gynecol Oncol. 2001 May; 81(2):213-5. . View in PubMed
  • Treatment of patients with ovarian carcinoma with pegylated liposomal doxorubicin: analysis of toxicities and predictors of outcome Cancer. 2001 Jan 01; 91(1):90-100. . View in PubMed
  • The use of a pelvic displacement prosthesis to exclude the small intestine from the radiation field following radical hysterectomy Gynecol Oncol. 2000 Dec; 79(3):438-43. . View in PubMed
  • Interrater Variability in Diagnosis of Cervical Biopsies from Women with HIV-1: Results from the Women’s Interagency HIV Study J Low Genit Tract Dis. 2000 Oct; 4(4):190-4. . View in PubMed
  • A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive Clin Cancer Res. 2000 Sep; 6(9):3406-16. . View in PubMed
  • Phase II study of liposomal doxorubicin in advanced gynecologic cancers Gynecol Oncol. 2000 Aug; 78(2):143-7. . View in PubMed
  • Effect of HIV infection on menstrual cycle length J Acquir Immune Defic Syndr. 2000 May 01; 24(1):68-75. . View in PubMed
  • A phase II study of gemcitabine and cisplatin in patients with advanced, persistent, or recurrent squamous cell carcinoma of the cervix Gynecol Oncol. 2000 Jan; 76(1):63-6. . View in PubMed
  • HIV-1 RNA in plasma and genital tract secretions in women infected with HIV-1 J Acquir Immune Defic Syndr. 1999 Oct 01; 22(2):124-31. . View in PubMed
  • Prevalence and predictors of squamous cell abnormalities in Papanicolaou smears from women infected with HIV-1Women’s Interagency HIV Study Group. J Acquir Immune Defic Syndr. 1999 May 01; 21(1):33-41. . View in PubMed
  • A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study Gynecol Oncol. 1999 May; 73(2):177-83. . View in PubMed
  • Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma N Engl J Med. 1999 Apr 15; 340(15):1154-61. . View in PubMed
  • Down-regulation of bcl-2 is a potential marker of the efficacy of progestin therapy in the treatment of endometrial hyperplasia Gynecol Oncol. 1999 Apr; 73(1):126-36. . View in PubMed
  • Cold-knife conization versus conization by the loop electrosurgical excision procedure: a randomized, prospective study Am J Obstet Gynecol. 1999 Feb; 180(2 Pt 1):276-82. . View in PubMed
  • Differences in p16 gene methylation and expression in benign and malignant ovarian tumors Gynecol Oncol. 1999 Jan; 72(1):87-92. . View in PubMed
  • Clinical utility? J Reprod Med. 1998 May; 43(5):403-7.. View in PubMed
  • Risk factors for trichomoniasis among women with human immunodeficiency virus (HIV) infection at a public clinic in Los Angeles County, California: implications for HIV prevention Am J Trop Med Hyg. 1998 Apr; 58(4):495-500. . View in PubMed
  • Influence of quantity of lymph-vascular space invasion on the risk of nodal metastases in women with early-stage squamous cancer of the cervix Gynecol Oncol. 1998 Mar; 68(3):220-5. . View in PubMed
  • Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination J Natl Cancer Inst. 1998 Feb 04; 90(3):238-42. . View in PubMed
  • Risk of residual invasive disease in women with microinvasive squamous cancer in a conization specimen Obstet Gynecol. 1997 Nov; 90(5):759-64. . View in PubMed
  • Phase I/II study of intraperitoneal floxuridine and platinums (cisplatin and/or carboplatin) Gynecol Oncol. 1997 Aug; 66(2):290-4. . View in PubMed
  • Carboplatin as a radiation sensitizer in locally advanced cervical cancer: a pilot study Gynecol Oncol. 1997 May; 65(2):336-42. . View in PubMed
  • Pelvic examination, tumor marker level, and gray-scale and Doppler sonography in the prediction of pelvic cancer Obstet Gynecol. 1997 Apr; 89(4):493-500. . View in PubMed
  • Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation J Clin Oncol. 1997 Mar; 15(3):987-93. . View in PubMed
  • Second-look laparotomy for stage III epithelial ovarian cancer: rationale and current issues Cancer Treat Rev. 1996 Nov; 21(6):499-511. . View in PubMed
  • Residual disease in the uterus after preoperative radiotherapy and hysterectomy in stage IB cervical carcinoma Am J Clin Oncol. 1996 Oct; 19(5):433-8. . View in PubMed
  • What is the role of reassessment laparoscopy in the management of gynecologic cancers in 1995? Gynecol Oncol. 1996 Mar; 60(3):454-61.. View in PubMed
  • Insulin-like growth factor binding proteins in a natural pre-ovulatory follicle from a woman with polycystic ovary syndrome Hum Reprod. 1995 Sep; 10(9):2248-52. . View in PubMed
  • Inadequate adherence to radiotherapy in Latina immigrants with carcinoma of the cervixPotential impact on disease free survival. Cancer. 1995 Mar 01; 75(5):1135-40. . View in PubMed
  • The role of endocervical curettage at cervical conization for high-grade dysplasia Obstet Gynecol. 1995 Feb; 85(2):197-201. . View in PubMed
  • Differentiation of benign and malignant adnexal masses: relative value of gray-scale, color Doppler, and spectral Doppler sonography AJR Am J Roentgenol. 1995 Feb; 164(2):381-6. . View in PubMed
  • The significance of positive margins in loop electrosurgical cone biopsies Obstet Gynecol. 1994 Dec; 84(6):996-1000. . View in PubMed
  • Paclitaxel (Taxol) in heavily pretreated ovarian cancer: antitumor activity and complications Ann Oncol. 1994 Nov; 5(9):827-33. . View in PubMed
  • Microsatellite instability in sporadic endometrial carcinoma J Natl Cancer Inst. 1994 Aug 17; 86(16):1216-21. . View in PubMed
  • Death from anaphylaxis to cisplatin: a case report Gynecol Oncol. 1994 Apr; 53(1):121-2. . View in PubMed
  • Platinum compounds in cervical and endometrial cancers: focus on carboplatin Semin Oncol. 1994 Apr; 21(2 Suppl 2):35-41; quiz 4258. . View in PubMed
  • Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma Cancer Res. 1994 Mar 15; 54(6):1604-7. . View in PubMed
  • Cervical cancer in pregnancy: reporting on planned delay in therapy Obstet Gynecol. 1993 Oct; 82(4 Pt 1):598-602. . View in PubMed
  • Concurrent interstitial radiotherapy and infusional chemotherapy for recurrent gynecologic malignancies Int J Gynecol Cancer. 1993 Sep; 3(5):304-310. . View in PubMed
  • Spinal cord compression in metastatic cervical cancer Gynecol Oncol. 1993 Feb; 48(2):269-71. . View in PubMed
  • Myxoid leiomyosarcoma of the uterus Gynecol Oncol. 1993 Feb; 48(2):277-80. . View in PubMed