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Leon Aksman

Assistant Professor of Research Neurology

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Email laksman@usc.edu
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Publications

  • Precise perivascular space segmentation on magnetic resonance imaging from Human Connectome Project-Aging. medRxiv. 2025 Mar 20.. View in PubMed
  • Elucidating distinct and common fMRI-complexity patterns in pre-adolescent children with Attention-Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Obsessive-Compulsive Disorder diagnoses. medRxiv. 2025 Jan 18.. View in PubMed
  • A longitudinal study of functional brain complexity in progressive Alzheimer’s disease. Alzheimers Dement (Amst). 2025 Jan-Mar; 17(1):e70059.. View in PubMed
  • Towards cascading genetic risk in Alzheimer’s disease. Brain. 2024 Aug 01; 147(8):2680-2690.. View in PubMed
  • Effect of Genetic Risk on the Relationship Between rs-fMRI Complexity and Tau and Amyloid PET in Alzheimer’s Disease. J Alzheimers Dis. 2024; 101(2):429-435.. View in PubMed
  • A data-driven study of Alzheimer’s disease related amyloid and tau pathology progression. Brain. 2023 12 01; 146(12):4935-4948.. View in PubMed
  • Comparison of genetic and health risk factors for mild cognitive impairment and Alzheimer’s disease between Hispanic and non-Hispanic white participants. Alzheimers Dement. 2023 11; 19(11):5086-5094.. View in PubMed
  • The temporal event-based model: Learning event timelines in progressive diseases. Imaging Neurosci (Camb). 2023 Aug 01; 1:1-19.. View in PubMed
  • Deep phenotyping and genomic data from a nationally representative study on dementia in India. Sci Data. 2023 01 20; 10(1):45.. View in PubMed
  • Investigating the factors that explain white matter hyperintensity load in older Indians. Brain Commun. 2023; 5(1):fcad008.. View in PubMed
  • Nomograms of human hippocampal volume shifted by polygenic scores. Elife. 2022 08 08; 11.. View in PubMed
  • Event-based modeling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data. Epilepsia. 2022 08; 63(8):2081-2095.. View in PubMed
  • Association of Amygdala Development With Different Forms of Anxiety in Autism Spectrum Disorder. Biol Psychiatry. 2022 06 01; 91(11):977-987.. View in PubMed
  • Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis. Neurology. 2022 04 26; 98(17):e1692-e1703.. View in PubMed
  • pySuStaIn: a Python implementation of the Subtype and Stage Inference algorithm. SoftwareX. 2021 Dec; 16.. View in PubMed
  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease. Nat Med. 2021 05; 27(5):871-881.. View in PubMed
  • Sequence of clinical and neurodegeneration events in Parkinson’s disease progression. Brain. 2021 04 12; 144(3):975-988.. View in PubMed
  • Ordinal SuStaIn: Subtype and Stage Inference for Clinical Scores, Visual Ratings, and Other Ordinal Data. Front Artif Intell. 2021; 4:613261.. View in PubMed
  • Serial CT analysis in idiopathic pulmonary fibrosis: comparison of visual features that determine patient outcome. Thorax. 2020 08; 75(8):648-654.. View in PubMed
  • Robust Markers and Sample Sizes for Multicenter Trials of Huntington Disease. Ann Neurol. 2020 05; 87(5):751-762.. View in PubMed
  • A comprehensive analysis of methods for assessing polygenic burden on Alzheimer’s disease pathology and risk beyond APOE. Brain Commun. 2020; 2(1):fcz047.. View in PubMed
  • Modeling longitudinal imaging biomarkers with parametric Bayesian multi-task learning. Hum Brain Mapp. 2019 09; 40(13):3982-4000.. View in PubMed
  • Making use of longitudinal information in pattern recognition. Hum Brain Mapp. 2016 12; 37(12):4385-4404.. View in PubMed

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