Ling Zheng, PhD

Chief, Clinical Analytics, for Keck Medical Center of USC

Associate Professor Of Research Neurology.

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Dr. Ling Zheng is an associate professor of research in the Department of Neurology, Keck School of Medicine, University of Southern California. She currently serves as Director of Clinical Quality Informatics at Keck Medical Center of USC (Keck Hospital + Norris Cancer Hospital). She served as Director of Biostatistics and Outcomes Assessment at LAC+USC Medical Center for 4 years. She holds a medical degree from Fujian Medical University, M.S. in Biostatistics, and Ph.D. in Epidemiology from University of Southern California. She has been active in the research area of antiatherogenic intervention on atherosclerosis progression, atherosclerotic vascular disease history and dementia, vascular disease risk factors in amyloid angiopathy for 15 years. Her current special interest is in advancing real world evidence-based approaches in cerebrovascular disease prevention and treatment, public and professional education in neurodegenerative disease management, and hospital quality improvement and outcomes management using national healthcare databases.


  • Trends in Ventriculostomy-Associated Infections and Mortality in Aneurysmal Subarachnoid Hemorrhage: Data From the Nationwide Inpatient Sample World Neurosurg. 2017 Mar; 99:599-604. . View in PubMed
  • Neuropsychological Profiles Differentiate Alzheimer Disease from Subcortical Ischemic Vascular Dementia in an Autopsy-Defined Cohort Dement Geriatr Cogn Disord. 2017; 44(1-2):1-11. . View in PubMed
  • Association of Serum Docosahexaenoic Acid With Cerebral Amyloidosis JAMA Neurol. 2016 Oct 01; 73(10):1208-1216. . View in PubMed
  • Differential effects of ischemic vascular disease and Alzheimer’s disease on brain atrophy and cognition J Cereb Blood Flow Metab. 2016 Jan; 36(1):204-15. . View in PubMed
  • Importance of hospital entry: walk-in STEMI and primary percutaneous coronary intervention West J Emerg Med. 2014 Feb; 15(1):81-7. . View in PubMed
  • A medical staff peer review system in a public teaching hospital–an internal quality improvement tool J Healthc Qual. 2014 Jan-Feb; 36(1):37-44. . View in PubMed
  • Increasing organ donation in Hispanic Americans: the role of media and other community outreach efforts JAMA Surg. 2014 Jan; 149(1):71-6. . View in PubMed
  • Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes Stroke. 2013 Oct; 44(10):2835-41. . View in PubMed
  • Time of day variation in door-to-balloon time for STEMI patients in Los Angeles County: does time of day make a difference? Acute Card Care. 2013 Sep; 15(3):52-7.. View in PubMed
  • Increasing intent to donate in Hispanic American high school students: results of a prospective observational study Transplant Proc. 2013 Jan-Feb; 45(1):13-9. . View in PubMed
  • A focused educational program after religious services to improve organ donation in Hispanic Americans Clin Transplant. 2012 Nov-Dec; 26(6):E634-40. . View in PubMed
  • Preservation of neurons of the nucleus basalis in subcortical ischemic vascular disease Arch Neurol. 2012 Jul; 69(7):879-86. . View in PubMed
  • Coronary artery disease is associated with cognitive decline independent of changes on magnetic resonance imaging in cognitively normal elderly adults J Am Geriatr Soc. 2012 Mar; 60(3):499-504. . View in PubMed
  • Alzheimers Res Ther. 2012 Jan 04; 4(1):1. . View in PubMed
  • Chinese-language montreal cognitive assessment for cantonese or mandarin speakers: age, education, and gender effects Int J Alzheimers Dis. 2012; 2012:204623. . View in PubMed
  • Undiagnosed depression and its correlates in a predominantly immigrant Hispanic neurology clinic Clin Neurol Neurosurg. 2011 Oct; 113(8):623-5. . View in PubMed
  • Cognitive effects of atypical antipsychotic medications in patients with Alzheimer’s disease: outcomes from CATIE-AD Am J Psychiatry. 2011 Aug; 168(8):831-9. . View in PubMed
  • Occipital neuralgia with and without migraine: difference in pain characteristics and risk factors Headache. 2011 Jan; 51(1):124-8. . View in PubMed
  • Category verbal fluency predicted changes in behavioral and psychological symptoms of dementia in patients with Alzheimer’s disease Psychiatry Clin Neurosci. 2010 Aug; 64(4):408-14. . View in PubMed
  • Weight of the obesity epidemic: rising stroke rates among middle-aged women in the United States Stroke. 2010 Jul; 41(7):1371-5. . View in PubMed
  • Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study Am J Psychiatry. 2010 May; 167(5):589-97. . View in PubMed
  • Sex-specific trends in midlife coronary heart disease risk and prevalence Arch Intern Med. 2009 Oct 26; 169(19):1762-6. . View in PubMed
  • Metabolic changes associated with second-generation antipsychotic use in Alzheimer’s disease patients: the CATIE-AD study Am J Psychiatry. 2009 May; 166(5):583-90. . View in PubMed
  • GFR estimates using cystatin C are superior to serum creatinine in adult patients with cystic fibrosis J Cyst Fibros. 2009 Jan; 8(1):19-25. . View in PubMed
  • The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia Int J Geriatr Psychiatry. 2008 Oct; 23(10):1040-50. . View in PubMed
  • Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia J Neurosci. 2008 Sep 17; 28(38):9585-97. . View in PubMed
  • Analysis of headache management in a busy emergency room in the United States Headache. 2008 Jun; 48(6):931-8. . View in PubMed
  • Neuropathological basis of magnetic resonance images in aging and dementia Ann Neurol. 2008 Jan; 63(1):72-80. . View in PubMed
  • Effect of antihypertensive therapy on progression of carotid intima-media thickness in patients with type 2 diabetes mellitus Am J Cardiol. 2007 Apr 01; 99(7):956-60. . View in PubMed
  • Cognitive impact of subcortical vascular and Alzheimer’s disease pathology Ann Neurol. 2006 Dec; 60(6):677-87. . View in PubMed
  • Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes Diabetes Care. 2006 Jul; 29(7):1545-53. . View in PubMed
  • Cardiopulmonary responses to eccentric and concentric resistance exercise in older adults Age Ageing. 2006 May; 35(3):291-7. . View in PubMed
  • Six-week improvements in muscle mass and strength during androgen therapy in older men J Gerontol A Biol Sci Med Sci. 2005 Dec; 60(12):1586-92. . View in PubMed
  • Category fluency in a latino sample: associations with age, education, gender, and language J Clin Exp Neuropsychol. 2005 Jul; 27(5):591-8. . View in PubMed
  • Effects of androgen therapy on adipose tissue and metabolism in older men J Clin Endocrinol Metab. 2004 Oct; 89(10):4863-72. . View in PubMed
  • Clinicopathological concordance of dementia diagnoses by community versus tertiary care clinicians Am J Alzheimers Dis Other Demen. 2004 May-Jun; 19(3):161-5. . View in PubMed
  • Time from diagnosis of type 2 diabetes to initiation of insulin therapy is related to carotid artery intima-media thickness Atherosclerosis. 2003 Oct; 170(2):293-9. . View in PubMed
  • Treatment with oxandrolone and the durability of effects in older men J Appl Physiol (1985). 2004 Mar; 96(3):1055-62. . View in PubMed