Luke Wiggins

Associate Professor of Clinical Surgery

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Overview

Luke McKee Wiggins, MD is an Assistant Professor of Surgery at the Keck School of Medicine and University of Southern California. He received his medical degree with research honors from the University of South Alabama College of Medicine. After medical school, he completed his residency in Adult Cardiothoracic Surgery at the University of Southern California. He then trained in Pediatric Cardiothoracic Surgery at Great Ormond Street Hospital in London where he gained experience and published on complex pediatric aortic valve repair and reconstruction techniques. Following this, he returned to Children’s Hospital Los Angeles to complete a congenital cardiac surgery fellowship under the mentorship of Dr. Vaughn Starnes at Children’s Hospital of Los Angeles.

Dr. Wiggins’s clinic and research interests include optimizing outcomes of neonatal cardiac surgery and the operative management of congenital heart valve disease in the pediatric population.

Publications

  • Durability of Right Ventricle to Pulmonary Artery Conduits Implanted in Patients Less Than One Year of Age. World J Pediatr Congenit Heart Surg. 2026 Aug 04; 21501351261458314.. View in PubMed
  • Going With the Flow: How Pulmonary Artery Flow Restrictors Reset the Clock on Timing of Neonatal Operative Repair. Ann Thorac Surg. 2026 Oct; 122(4):1062-1063.. View in PubMed
  • Commentary: Qualitative evaluation of regurgitant jet after Ross-When being eccentric goes wrong. J Thorac Cardiovasc Surg. 2026 Aug; 172(2):227-228.. View in PubMed
  • Gerbode-ish Defect: A Congenital Left Ventricular-to-Right Atrium Shunt. JACC Case Rep. 2025 Aug 20; 30(24):104742.. View in PubMed
  • Modelling right and left ventricular adaptation over time after tetralogy of Fallot repair and the need for pulmonary valve replacement in adolescence. Cardiol Young. 2025 Jul; 35(7):1319-1328.. View in PubMed
  • The complex and hazardous course for heterotaxy-associated congenital heart disease. JTCVS Open. 2025 Aug; 26:196-206.. View in PubMed
  • A Coronary Challenge: Management of Dextro-Transposition With Levo-Malposed Great Vessels. World J Pediatr Congenit Heart Surg. 2025 07; 16(4):549-551.. View in PubMed
  • Surgical outcomes of the reinforced Ross procedure in the pediatric population. JTCVS Open. 2025 Apr; 24:341-349.. View in PubMed
  • Incidence and Prognosis of Surgical Heart Block in Patients with L-transposition of the Great Arteries. Pediatr Cardiol. 2026 Feb; 47(2):535-541.. View in PubMed
  • The landscape of congenital heart disease treated with the Ross procedure. J Thorac Cardiovasc Surg. 2025 03; 169(3):974-984.e4.. View in PubMed