Marc Vermulst

Assistant Professor of Gerontology

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Publications

  • Transcript errors generate amyloid-like proteins in huwman cells Nat Commun. 2024 Oct 07; 15(1):8676. . View in PubMed
  • Effects of the glyphosate-based herbicide roundup on Celegans and S. cerevisiae mortality, reproduction, and transcription fidelity. Environ Pollut. 2024 Sep 01; 356:124203. . View in PubMed
  • MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations Nucleic Acids Res. 2024 Aug 16. . View in PubMed
  • Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging Geroscience. 2024 Apr 03. . View in PubMed
  • The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis Acta Neuropathol Commun. 2024 02 21; 12(1):30. . View in PubMed
  • Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51):e2306767120. . View in PubMed
  • Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging bioRxiv. 2023 Nov 27. . View in PubMed
  • Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold bioRxiv. 2023 Apr 28. . View in PubMed
  • Evolutionary conservation of the fidelity of transcription Nat Commun. 2023 03 20; 14(1):1547. . View in PubMed
  • Identification of RBM46 as a novel APOBEC1 cofactor for C-to-U RNA-editing activity J Mol Biol. 2023 12 15; 435(24). . View in PubMed
  • The fidelity of transcription in human cells Proc Natl Acad Sci U S A. 2023 01 31; 120(5):e2210038120. . View in PubMed
  • Genome-wide surveillance of transcription errors in response to genotoxic stress Proc Natl Acad Sci U S A. 2021 01 05; 118(1). . View in PubMed
  • Correction to: Somatic mutations in neurons during aging and neurodegeneration Acta Neuropathol. 2020 09; 140(3):415. . View in PubMed
  • Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in Celegans. BMC Biol. 2020 02 24; 18(1):18. . View in PubMed
  • Oxygen Consumption Measurements in Caenorhabditis elegans Using the Seahorse XF24 Bio Protoc. 2019 Jul 05; 9(13):e3288. . View in PubMed
  • Increased burden of mitochondrial DNA deletions and point mutations in early-onset age-related hearing loss in mitochondrial mutator mice Exp Gerontol. 2019 10 01; 125:110675. . View in PubMed
  • Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing CardiomyopathyCell Metab. 2019 01 08; 29(1):78-90. e5. . View in PubMed
  • Somatic mutations in neurons during aging and neurodegeneration Acta Neuropathol. 2018 06; 135(6):811-826. . View in PubMed
  • Multiple Molecular Mechanisms Rescue mtDNA Disease in C elegans. Cell Rep. 2018 03 20; 22(12):3115-3125. . View in PubMed
  • Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms J Vis Exp. 2018 09 13; (139). . View in PubMed
  • The landscape of transcription errors in eukaryotic cells Sci Adv. 2017 10; 3(10):e1701484. . View in PubMed
  • Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice PLoS One. 2017; 12(2):e0171159. . View in PubMed
  • Linking mitochondrial dynamics to mitochondrial protein quality control Curr Opin Genet Dev. 2016 06; 38:68-74. . View in PubMed
  • Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan Nat Commun. 2015 Oct 14; 6:8738. . View in PubMed
  • Transcription errors induce proteotoxic stress and shorten cellular lifespan Nat Commun. 2015 Aug 25; 6:8065. . View in PubMed
  • Decreased mitochondrial DNA mutagenesis in human colorectal cancer PLoS Genet. 2012; 8(6):e1002689. . View in PubMed
  • Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations Cell. 2010 Apr 16; 141(2):280-9. . View in PubMed
  • On mitochondria, mutations, and methodology Cell Metab. 2009 Dec; 10(6):437. . View in PubMed
  • Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging Circulation. 2009 Jun 02; 119(21):2789-97. . View in PubMed
  • Quantification of random mutations in the mitochondrial genome Methods. 2008 Dec; 46(4):263-8. . View in PubMed
  • DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice Nat Genet. 2008 Apr; 40(4):392-4. . View in PubMed
  • Mitochondrial point mutations do not limit the natural lifespan of mice Nat Genet. 2007 Apr; 39(4):540-3. . View in PubMed