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Mark D. Krieger, MD

Professor of Clinical Neurological Surgery

Senior Vice President and Surgeon-in-Chief

Medical Director of Neurological Institute

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Phone +1 323 361 2104
Email mkrieger@chla.usc.edu
CTSI Profile

Publications

  • The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium J Neurosurg Pediatr. 2024 Apr 05; 1-9. . View in PubMed
  • Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus J Neurosurg. 2024 Apr 01; 140(4):1117-1128. . View in PubMed
  • Shunt timing in low-weight infants in the treatment of hydrocephalus J Neurosurg Pediatr. 2024 Mar 29; 1-10. . View in PubMed
  • A re-evaluation of the Endoscopic Third Ventriculostomy Success Score: a Hydrocephalus Clinical Research Network study J Neurosurg Pediatr. 2024 Feb 09; 1-11. . View in PubMed
  • Surgical management of pediatric spinal aneurysmal bone cysts: patient series J Neurosurg Case Lessons. 2024 Jan 22; 7(4). . View in PubMed
  • Myelomeningocele repair at pediatric hospitals: association with routine discharge and shorter hospital stay J Neurosurg Pediatr. 2023 Sep 01; 32(3):376-383. . View in PubMed
  • Interhospital transfer of pediatric patients with malignant brain tumor not associated with increased mortality, but safe routine discharge J Neurosurg Pediatr. 2023 02 01; 31(2):124-131. . View in PubMed
  • Comparison of outcomes in the management of abdominal pseudocyst in children with shunted hydrocephalus: a Hydrocephalus Clinical Research Network study J Neurosurg Pediatr. 2023 09 01; 32(3):312-323. . View in PubMed
  • Pediatric patients with malignant brain tumor treated at children’s hospitals: association with fewer unplanned readmissions J Neurosurg Pediatr. 2023 09 01; 32(3):324-331. . View in PubMed
  • Low-pass whole-genome and targeted sequencing of cell-free DNA from cerebrospinal fluid in pediatric patients with central nervous system tumors Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad077. . View in PubMed
  • Endoscopic third ventriculostomy in previously shunt-treated patients J Neurosurg Pediatr. 2022 Jul 29; 1-9. . View in PubMed
  • Hydrocephalus surveillance following CSF diversion: a modified Delphi study J Neurosurg Pediatr. 2022 Jun 17; 1-11. . View in PubMed
  • The Hydrocephalus Clinical Research Network quality improvement initiative: the role of antibiotic-impregnated catheters and vancomycin wound irrigation J Neurosurg Pediatr. 2022 Jun 01; 29(6):711-718. . View in PubMed
  • Endoscopic third ventriculostomy revision after failure of initial endoscopic third ventriculostomy and choroid plexus cauterization J Neurosurg Pediatr. 2022 Apr 22; 1-10. . View in PubMed
  • Complications and outcomes of posterior fossa decompression with duraplasty versus without duraplasty for pediatric patients with Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium J Neurosurg Pediatr. 2022 Apr 15; 1-13. . View in PubMed
  • Anterior versus posterior entry site for ventriculoperitoneal shunt insertion: a randomized controlled trial by the Hydrocephalus Clinical Research Network J Neurosurg Pediatr. 2022 Mar 01; 29(3):257-267. . View in PubMed
  • Readmissions after ventricular shunting in pediatric patients with hydrocephalus: a Nationwide Readmissions Database analysis J Neurosurg Pediatr. 2021 Aug 20; 28(5):553-562. . View in PubMed
  • Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium J Neurosurg Pediatr. 2021 Jun 18; 1-9. . View in PubMed
  • Treatment strategies for hydrocephalus related to Dandy-Walker syndrome: evaluating procedure selection and success within the Hydrocephalus Clinical Research Network J Neurosurg Pediatr. 2021 Apr 30; 28(1):93-101. . View in PubMed
  • Postoperative facial palsy after pediatric posterior fossa tumor resection J Neurosurg Pediatr. 2021 Mar 12; 27(5):566-571. . View in PubMed
  • Dural augmentation approaches and complication rates after posterior fossa decompression for Chiari I malformation and syringomyelia: a Park-Reeves Syringomyelia Research Consortium study J Neurosurg Pediatr. 2021 Feb 12; 27(4):459-468. . View in PubMed
  • Occipital-Cervical Fusion and Ventral Decompression in the Surgical Management of Chiari-1 Malformation and Syringomyelia: Analysis of Data From the Park-Reeves Syringomyelia Research Consortium Neurosurgery. 2021 01 13; 88(2):332-341. . View in PubMed
  • Predictors of fast and ultrafast shunt failure in pediatric hydrocephalus: a Hydrocephalus Clinical Research Network study J Neurosurg Pediatr. 2020 Dec 18; 27(3):277-286. . View in PubMed
  • Surgical resource utilization after initial treatment of infant hydrocephalus: comparing ETV, early experience of ETV with choroid plexus cauterization, and shunt insertion in the Hydrocephalus Clinical Research Network J Neurosurg Pediatr. 2020 Jun 19; 26(4):337-345. . View in PubMed
  • Resolution of neonatal posthemorrhagic ventricular dilation coincident with patent ductus arteriosus ligation: case report J Neurosurg Pediatr. 2020 May 22; 26(3):255-261. . View in PubMed
  • EditorialEarly lessons in the management of COVID-19 for the pediatric neurosurgical community from the leadership of the American Society of Pediatric Neurosurgeons. J Neurosurg Pediatr. 2020 Apr 10; 26(1):1-2. . View in PubMed
  • Pediatric neurosurgery training during residency in the United States: a program director survey J Neurosurg Pediatr. 2020 Mar 20; 26(1):6-12. . View in PubMed
  • Transcriptional analyses of adult and pediatric adamantinomatous craniopharyngioma reveals similar expression signatures regarding potential therapeutic targets Acta Neuropathol Commun. 2020 05 13; 8(1):68. . View in PubMed
  • Bilateral Congenital Posterior Hemivertebrae and Lumbar Spinal Stenosis Treated With Posterior Spinal Fusion and Instrumentation J Am Acad Orthop Surg Glob Res Rev. 2019 Oct; 3(10). . View in PubMed
  • Radiological and clinical predictors of scoliosis in patients with Chiari malformation type I and spinal cord syrinx from the Park-Reeves Syringomyelia Research Consortium J Neurosurg Pediatr. 2019 Aug 16; 1-8. . View in PubMed
  • Risk Factors for Preoperative Developmental Delay in Patients with Nonsyndromic Sagittal Craniosynostosis Plast Reconstr Surg. 2019 01; 143(1):133e-139e. . View in PubMed
  • Imaging Features Predictive of Recurrence in Pediatric Intracranial Germ-Cell Tumors Pediatr Neurosurg. 2019; 54(3):173-180. . View in PubMed
  • Novel Surgical and Radiologic Risk Factors for Progression or Recurrence of Pediatric Pilocytic Astrocytoma Pediatr Neurosurg. 2019; 54(6):375-385. . View in PubMed
  • Rare Pediatric Invasive Gliofibroma Has BRAFV600E Mutation and Transiently Responds to Targeted Therapy Before Progressive Clonal Evolution JCO Precis Oncol. 2019; 3. . View in PubMed
  • Dynamic MRI in the Evaluation of Atlantoaxial Stability in Pediatric Down Syndrome Patients Pediatr Neurosurg. 2019; 54(1):12-20. . View in PubMed
  • Development of best practices to minimize wound complications after complex tethered spinal cord surgery: a modified Delphi study J Neurosurg Pediatr. 2018 Dec 01; 22(6):701-709. . View in PubMed
  • Assessing the Benefit-Risk Profile for Pediatric Implantable Auditory Prostheses Ther Innov Regul Sci. 2018 09; 52(5):669-679. . View in PubMed
  • Seizure outcomes of supratentorial brain tumor resection in pediatric patients Neuro Oncol. 2018 08 02; 20(9):1272-1281. . View in PubMed
  • Treatment patterns of children with spine and spinal cord tumors: national outcomes and review of the literature Childs Nerv Syst. 2017 Aug; 33(8):1357-1365. . View in PubMed
  • The effect of NACHRI children’s hospital designation on outcome in pediatric malignant brain tumors J Neurosurg Pediatr. 2017 Aug; 20(2):149-157. . View in PubMed
  • Return of motor evoked potentials after knee flexion in the setting of high-grade spondylolisthesis Eur Spine J. 2017 03; 26(3):619-622. . View in PubMed
  • Initial Results of a Safety and Feasibility Study of Auditory Brainstem Implantation in Congenitally Deaf Children Otol Neurotol. 2017 02; 38(2):212-220. . View in PubMed
  • Infection rate correlated with time to repair of open neural tube defects (myelomeningoceles): an institutional and national study Childs Nerv Syst. 2016 Sep; 32(9):1675-81. . View in PubMed
  • Re-irradiation of Recurrent Pineal Germ Cell Tumors with Radiosurgery: Report of Two Cases and Review of Literature Cureus. 2016 Apr 25; 8(4):e585. . View in PubMed
  • Cross-Sectional Analysis on Racial and Economic Disparities Affecting Mortality in Preterm Infants with Posthemorrhagic Hydrocephalus World Neurosurg. 2016 Apr; 88:399-410. . View in PubMed
  • Surgical management of hydrocephalus secondary to intraventricular hemorrhage in the preterm infant J Neurosurg Pediatr. 2016 Mar; 17(3):278-84. . View in PubMed
  • Trends in hospitalization of preterm infants with intraventricular hemorrhage and hydrocephalus in the United States, 2000-2010 J Neurosurg Pediatr. 2016 Mar; 17(3):260-9. . View in PubMed
  • Reevaluating the weekend effect on patients with hydrocephalus undergoing operative shunt intervention J Neurosurg Pediatr. 2016 Feb; 17(2):156-162. . View in PubMed
  • Parylene MEMS patency sensor for assessment of hydrocephalus shunt obstruction Biomed Microdevices. 2016 10; 18(5):87. . View in PubMed
  • Molecular subgroups of medulloblastoma identification using noninvasive magnetic resonance spectroscopy Neuro Oncol. 2016 Jan; 18(1):126-31. . View in PubMed
  • Regulatory and funding strategies to develop a safety study of an auditory brainstem implant in young children who are deaf Ther Innov Regul Sci. 2015 Sep; 49(5):659-665. . View in PubMed
  • Differentiating infantile tumors with diffusion imaging J Neurosurg Pediatr. 2015 Aug; 16(2):117-8. . View in PubMed
  • Racial and socioeconomic disparities in outcomes following pediatric cerebrospinal fluid shunt procedures J Neurosurg Pediatr. 2015 Jun; 15(6):560-6. . View in PubMed
  • Introduction: craniosynostosis: modern treatment strategies Neurosurg Focus. 2015 May; 38(5):E1. . View in PubMed
  • Intracranial hypertension after surgical correction for craniosynostosis: a systematic review Neurosurg Focus. 2015 May; 38(5):E6. . View in PubMed
  • Risk factors for hydrocephalus and neurological deficit in children born with an encephalocele J Neurosurg Pediatr. 2015 Apr; 15(4):392-8. . View in PubMed
  • Tumor-associated macrophages in SHH subgroup of medulloblastomas Clin Cancer Res. 2015 Mar 15; 21(6):1457-65. . View in PubMed
  • Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia Front Oncol. 2015; 5:191. . View in PubMed
  • The association between dental health and procedures and developing shunt infections in pediatric patients J Neurosurg Pediatr. 2014 Nov; 14(5):508-13. . View in PubMed
  • What is the risk of infecting a cerebrospinal fluid-diverting shunt with percutaneous tapping? J Neurosurg Pediatr. 2014 Oct; 14(4):336-9.. View in PubMed
  • Deep brain stimulation evoked potentials may relate to clinical benefit in childhood dystonia Brain Stimul. 2014 Sep-Oct; 7(5):718-26. . View in PubMed
  • PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas Clin Cancer Res. 2014 Feb 15; 20(4):827-36. . View in PubMed
  • Deep brain stimulation in children and young adults with secondary dystonia: the Children’s Hospital Los Angeles experience Neurosurg Focus. 2013 Nov; 35(5):E7. . View in PubMed
  • Positional plagiocephaly: an analysis of the literature on the effectiveness of current guidelines Neurosurg Focus. 2013 Oct; 35(4):E1. . View in PubMed
  • Management of plagiocephaly Neurosurg Focus. 2013 Oct; 35(4):Introduction. . View in PubMed
  • Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children’s Hospital Los Angeles (CHLA) experience, 1991-2010 Pediatr Blood Cancer. 2012 Jun; 58(6):905-9. . View in PubMed
  • Spinal arachnoid cysts in the pediatric population: report of 31 cases and a review of the literature J Neurosurg Pediatr. 2012 Apr; 9(4):432-41. . View in PubMed
  • Microdeletion del(22)(q122) encompassing the facial development-associated gene, MN1 (meningioma 1) in a child with Pierre-Robin sequence (including cleft palate) and neurofibromatosis 2 (NF2): a case report and review of the literature. BMC Med Genet. 2012 Mar 22; 13:19. . View in PubMed
  • Supratentorial ependymoma in children: to observe or to treat following gross total resection? Pediatr Blood Cancer. 2012 Mar; 58(3):380-3.. View in PubMed
  • Symptoms before and after posterior fossa surgery in pediatric patients Pediatr Neurosurg. 2012; 48(1):21-5. . View in PubMed
  • Elevated citrate in pediatric astrocytomas with malignant progression Neuro Oncol. 2011 Oct; 13(10):1107-17. . View in PubMed
  • Posterior interhemispheric retrocallosal approach to pineal region and posterior fossa lesions in a pediatric population J Neurosurg Pediatr. 2011 May; 7(5):527-33. . View in PubMed
  • Incidence of venous infarction after sacrificing middle-third superior sagittal sinus cortical bridging veins in a pediatric population J Neurosurg Pediatr. 2011 Mar; 7(3):224-8. . View in PubMed
  • Normally shaped heads with no sutures, normally shaped heads with abnormal sutures, and abnormally shaped heads with normal sutures J Craniofac Surg. 2011 Jan; 22(1):173-7. . View in PubMed
  • Scoliosis and Chiari malformation Type I in children J Neurosurg Pediatr. 2011 Jan; 7(1):25-9. . View in PubMed
  • Surgical management of primary central nervous system germ cell tumors: proceedings from the Second International Symposium on Central Nervous System Germ Cell Tumors J Neurosurg Pediatr. 2010 Aug; 6(2):125-30. . View in PubMed
  • Evaluation of intracranial cerebrospinal fluid cytology in staging pediatric medulloblastomas, supratentorial primitive neuroectodermal tumors, and ependymomas J Neurosurg Pediatr. 2010 Aug; 6(2):131-6. . View in PubMed
  • The role of stereotactic radiotherapy in the management of ependymomas Childs Nerv Syst. 2009 Oct; 25(10):1269-73. . View in PubMed
  • Metabolism of orthotopic mouse brain tumor models Mol Imaging. 2009 Jul-Aug; 8(4):199-208. . View in PubMed
  • Surgical treatment of rathke cleft cysts in children Neurosurgery. 2009 Jun; 64(6):1132-7; author reply 1037-8. . View in PubMed
  • Use of cranial fixation pins in pediatric neurosurgery Neurosurgery. 2008 Apr; 62(4):913-8; discussion 918-9. . View in PubMed
  • Craniospinal Langerhans cell histiocytosis in children: 30 years’ experience at a single institution J Neurosurg Pediatr. 2008 Mar; 1(3):187-95. . View in PubMed
  • Metabolism of diffuse intrinsic brainstem gliomas in children Neuro Oncol. 2008 Feb; 10(1):32-44. . View in PubMed
  • Pediatric shunt malfunction without ventricular dilatation Pediatr Neurosurg. 2008; 44(2):128-32. . View in PubMed
  • Pathogenesis and treatment of intracranial arachnoid cysts in pediatric patients younger than 2 years of age Neurosurg Focus. 2007; 22(2):E1. . View in PubMed
  • Quantitative short echo time 1H-MR spectroscopy of untreated pediatric brain tumors: preoperative diagnosis and characterization AJNR Am J Neuroradiol. 2006 Mar; 27(3):560-72. . View in PubMed
  • Craniopharyngioma in childhood Adv Pediatr. 2006; 53:183-209. . View in PubMed
  • Chemical analysis of fluid obtained from intracranial arachnoid cysts in pediatric patients J Neurosurg. 2005 Nov; 103(5 Suppl):427-32. . View in PubMed
  • Untreated pediatric primitive neuroectodermal tumor in vivo: quantitation of taurine with MR spectroscopy Radiology. 2005 Sep; 236(3):1020-5. . View in PubMed
  • Craniopharyngiomas of childhood: the CHLA experience Childs Nerv Syst. 2005 Aug; 21(8-9):785-9. . View in PubMed
  • Craniotomy for fenestration of multiloculated hydrocephalus in pediatric patients Neurosurgery. 2005 Jul; 57(1 Suppl):100-6; discussion 100-6. . View in PubMed
  • Effects of surgical resection and adjuvant therapy on pediatric intracranial ependymomas Expert Rev Neurother. 2005 Jul; 5(4):465-71. . View in PubMed
  • Atypical teratoid/rhabdoid tumors of the central nervous system: management and outcomes Neurosurg Focus. 2005 Jun 15; 18(6A):E8. . View in PubMed
  • Differentiation of choroid plexus tumors by advanced magnetic resonance spectroscopy Neurosurg Focus. 2005 Jun 15; 18(6A):E4. . View in PubMed
  • Proton-decoupled 31P MRS in untreated pediatric brain tumors Magn Reson Med. 2005 Jan; 53(1):22-9. . View in PubMed
  • Atypical teratoid/rhabdoid tumor: an unusual presentation Neuroradiology. 2004 Oct; 46(10):834-7. . View in PubMed
  • Magnetic resonance spectroscopy of atypical diffuse pontine masses Neurosurg Focus. 2003 Jul 15; 15(1):E5. . View in PubMed
  • Assessment of long-term remission of acromegaly following surgery J Neurosurg. 2003 Apr; 98(4):719-24. . View in PubMed
  • Invasive pituitary adenomas: significance of proliferation parameters Pituitary. 1999 Aug; 2(2):117-22. . View in PubMed
  • Toward a simpler surgical management of Chiari I malformation in a pediatric population Pediatr Neurosurg. 1999 Mar; 30(3):113-21. . View in PubMed
  • Role of stereotactic biopsy in the diagnosis and management of brain tumors Semin Surg Oncol. 1998 Jan-Feb; 14(1):13-25. . View in PubMed
  • Recurrence patterns and anaplastic change in a long-term study of pilocytic astrocytomas Pediatr Neurosurg. 1997 Jul; 27(1):1-11. . View in PubMed
  • Spinal extradural leiomyoma in a pediatric patient with acquired immunodeficiency syndrome: case report Neurosurgery. 1997 May; 40(5):1080-2. . View in PubMed
  • Septic cavernous sinus thrombosis following transsphenoidal craniotomyCase report. J Neurosurg. 1996 Nov; 85(5):949-52. . View in PubMed
  • Gunshot wounds to the head in an urban setting Neurosurg Clin N Am. 1995 Oct; 6(4):605-10. . View in PubMed
  • Iatrogenic intraspinal epidermoid tumor: two cases and a review of the literature Spine (Phila Pa 1976). 2004 Jan 01; 29(1):E15-8. . View in PubMed

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