Keck School Faculty

Mark Masaru Urata

Mark Masaru Urata

Professor Of Clinical of Surgery
1510 San Palbo St. Health Sciences Campus Los Angeles

Early Ophthalmology Findings in Nonsyndromic Craniosynostosis J Craniofac Surg. 2023 Jun 01; 34(4):1259-1261. . View in PubMed

A Murine Calvarial Defect Model for the Investigation of the Osteogenic Potential of Newborn Umbilical Cord Mesenchymal Stem Cells in Bone Regeneration Plast Reconstr Surg. 2023 May 24. . View in PubMed

Cleft Palate Craniofac J. 2023 04; 60(4):430-445. . View in PubMed

Rethinking the Rule of 10s: Early Cleft Lip Repair Improves Weight Gain Cleft Palate Craniofac J. 2023 03; 60(3):306-312. . View in PubMed

Orbital Foraminal Morphometrics in Nonsyndromic Unilateral Coronal Craniosynostosis Ann Plast Surg. 2023 06 01; 90(6S Suppl 5):S677-S680. . View in PubMed

Comparative Benefits of Open versus Closed Reduction of Condylar Fractures: A Systematic Review and Meta-Analysis Plast Reconstr Surg. 2023 04 01; 151(4):664e-672e. . View in PubMed

From Bedside to Bench and Back: Advancing Our Understanding of the Pathophysiology of Cleft Palate and Implications for the Future Cleft Palate Craniofac J. 2022 Dec 01; 10556656221142098. . View in PubMed

Premaxillary Setback in Bilateral Cleft Lip and Palate Repair Cleft Palate Craniofac J. 2022 Nov 29; 10556656221130166. . View in PubMed

Craniofacial Dysmorphology in Infants With Non-Syndromic Unilateral Coronal Craniosynostosis J Craniofac Surg. 2022 Sep 01; 33(6):1903-1908. . View in PubMed

Syndromic Synostosis: Frontofacial Surgery Oral Maxillofac Surg Clin North Am. 2022 Aug; 34(3):459-466. . View in PubMed

Midface Growth Potential in Unoperated Clefts: A Systematic Review and Meta-Analysis J Craniofac Surg. 2022 May 01; 33(3):774-778. . View in PubMed

Establishing a Novel Treatment Algorithm for Pediatric Mandibular Tumor Reconstruction J Craniofac Surg. 2022 May 01; 33(3):744-749. . View in PubMed

Reconstructive Surgeons as Essential Operative Consultants: Quantifying the True Value of Plastic Surgeons to an Academic Medical Center Plast Reconstr Surg. 2022 Apr 01; 149(4):767e-773e. . View in PubMed

Increased Distraction Magnitude Leads to Greater Reduction in the Apnea-Hypopnea Index in Infants With Robin Sequence J Oral Maxillofac Surg. 2022 09; 80(9):1486-1492. . View in PubMed

Early Cleft Lip Repair: Demonstrating Efficacy in the First 100 Patients Plast Reconstr Surg. 2022 11 01; 150(5):1073-1080. . View in PubMed

Appropriateness of Computed Tomography Scanning in the Diagnosis of Craniosynostosis J Craniofac Surg. 2022 Jan-Feb 01; 33(1):222-225. . View in PubMed

Orthognathic Surgery Rate in Cleft Care J Craniofac Surg. 2022 Jan-Feb 01; 33(1):87-92. . View in PubMed

The clinical manifestations, molecular mechanisms and treatment of craniosynostosis Dis Model Mech. 2022 04 01; 15(4). . View in PubMed

Assessing the Safety of a Novel Neonatal Anesthesia Protocol: A Review of 101 Patients With Early Cleft Lip Repair J Craniofac Surg. 2021 Nov-Dec 01; 32(8):2682-2686. . View in PubMed

Sphenotemporal and Fronto-Orbital Dysmorphology in Unilateral Coronal Synostosis Using Geometric Morphometric Curve-Based Analysis J Craniofac Surg. 2021 Oct 01; 32(7):2449-2451. . View in PubMed

Is Le Fort I Distraction Enough to Treat Severe Midface Hypoplasia? J Craniofac Surg. 2021 Jul-Aug 01; 32(5):1716-1720.. View in PubMed

Cleft Lip and Palate: Le Fort I Distraction Using an Internal Device Clin Plast Surg. 2021 Jul; 48(3):407-417. . View in PubMed

Nasoalveolar Molding: Assessing the Burden of Care J Craniofac Surg. 2021 Mar-Apr 01; 32(2):574-577. . View in PubMed

Simultaneous LeFort III and LeFort I Osteotomies in Craniometaphyseal Dysplasia Cleft Palate Craniofac J. 2021 12; 58(12):1560-1568. . View in PubMed

Factors Associated With Delay in Cleft Surgery at a Tertiary Children's Hospital in a Major US Metropolitan City Cleft Palate Craniofac J. 2021 12; 58(12):1508-1516. . View in PubMed

Postoperative helmet therapy following fronto-orbital advancement and cranial vault remodeling in patients with unilateral coronal synostosis Am J Med Genet A. 2021 09; 185(9):2670-2675. . View in PubMed

Mesenchymal stem cells and three-dimensional-osteoconductive scaffold regenerate calvarial bone in critical size defects in swine Stem Cells Transl Med. 2021 08; 10(8):1170-1183. . View in PubMed

Reply: Simultaneous Midface Advancement and Orthognathic Surgery: A Powerful Technique for Managing Midface Hypoplasia and Malocclusion Plast Reconstr Surg. 2021 09 01; 148(3):504e-505e. . View in PubMed

Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in CraniosynostosisCell. 2021 01 07; 184(1):243-256. e18. . View in PubMed

Reciprocal interaction between mesenchymal stem cells and transit amplifying cells regulates tissue homeostasis Elife. 2021 01 22; 10. . View in PubMed

Rotation of the Ipsilateral Supraorbital Rim Around the Horizontal Axis in Unilateral Coronal Synostosis: A Craniometric Analysis of the Emergence Profile J Craniofac Surg. 2021 Jan-Feb 01; 32(1):168-172. . View in PubMed

Craniofacial Dysmorphology in Unilateral Coronal Synostosis Using Three-Dimensional Landmark-Based Analysis With Generalized Procrustes Superimposition J Craniofac Surg. 2021 Jan-Feb 01; 32(1):16-20. . View in PubMed

Velopharyngeal Insufficiency Impact and Nasopharngoscopy Discomfort and Cooperation: Patient, Parent, and Provider Perspectives J Craniofac Surg. 2020 Sep; 31(6):1713-1716. . View in PubMed

Orthodontic Considerations for Cleft Orthognathic Surgery Oral Maxillofac Surg Clin North Am. 2020 May; 32(2):249-267. . View in PubMed

Temporal Fat Grafting in Children With Craniofacial Anomalies Ann Plast Surg. 2020 11; 85(5):505-510. . View in PubMed

Outcomes of Intracranial Versus Subcranial Approaches to the Frontofacial Skeleton J Oral Maxillofac Surg. 2020 09; 78(9):1609-1616. . View in PubMed

Simultaneous Midface Advancement and Orthognathic Surgery: A Powerful Technique for Managing Midface Hypoplasia and Malocclusion Plast Reconstr Surg. 2020 06; 145(6):1067e-1072e. . View in PubMed

The Monobloc Distraction With Facial Bipartition: Outcomes of Simultaneous Multidimensional Facial Movement Compared With Monobloc Distraction or Facial Bipartition Alone Ann Plast Surg. 2020 05; 84(5S Suppl 4):S288-S294. . View in PubMed

Evaluation of Obstructive Sleep Apnea in Prone Versus Nonprone Body Positioning With Polysomnography in Infants With Robin Sequence Cleft Palate Craniofac J. 2020 02; 57(2):141-147. . View in PubMed

Sebaceous Nevus of the Scalp J Craniofac Surg. 2020 Jan/Feb; 31(1):257-260. . View in PubMed

Less Is More in Congenital and Pediatric Nasal Lesions J Craniofac Surg. 2019 Sep; 30(6):1777-1779. . View in PubMed

Cosmetically Challenging Congenital Melanocytic Nevi Ann Plast Surg. 2019 05; 82(5S Suppl 4):S306-S309. . View in PubMed

A Single Lab Test to Aid Pierre Robin Sequence Severity Diagnosis Cleft Palate Craniofac J. 2019 03; 56(3):298-306. . View in PubMed

Risk Factors for Preoperative Developmental Delay in Patients with Nonsyndromic Sagittal Craniosynostosis Plast Reconstr Surg. 2019 01; 143(1):133e-139e. . View in PubMed

Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars Elife. 2019 07 01; 8. . View in PubMed

Alternatives to Autologous Bone Graft in Alveolar Cleft Reconstruction: The State of Alveolar Tissue Engineering J Craniofac Surg. 2018 May; 29(3):584-593. . View in PubMed

Predictors of Failure in Infant Mandibular Distraction Osteogenesis J Oral Maxillofac Surg. 2018 09; 76(9):1955-1965. . View in PubMed

To Admit or Not to Admit: That is the Cleft Lip QuestionConfirming the Safety of Outpatient Cleft Lip Repair. Plast Reconstr Surg. 2018 07; 142(1):159-168. . View in PubMed

External Port Tissue Expansion in the Pediatric Population: Confirming Its Safety and Efficacy Plast Reconstr Surg. 2018 06; 141(6):883e-890e. . View in PubMed

Impact of the Distance of Maxillary Advancement on Horizontal Relapse After Orthognathic Surgery Cleft Palate Craniofac J. 2018 04; 55(4):546-553. . View in PubMed

Dental, Oral, and Craniofacial Regenerative Medicine: Transforming Biotechnologies for Innovating Patient Care J Dent Res. 2018 04; 97(4):361-363. . View in PubMed

Is Postoperative Intensive Care Unit Care Necessary following Cranial Vault Remodeling for Sagittal Synostosis? Plast Reconstr Surg. 2017 Dec; 140(6):1235-1239.. View in PubMed

Proteus Syndrome With a Cranial Intraosseous Lipoma J Craniofac Surg. 2017 Nov; 28(8):e771-e773. . View in PubMed

Three-Dimensional Cone Beam Computed Tomography Volumetric Outcomes of rhBMP-2/Demineralized Bone Matrix versus Iliac Crest Bone Graft for Alveolar Cleft Reconstruction Plast Reconstr Surg. 2017 Oct; 140(4):767-774. . View in PubMed

A Comparative Analysis of Recombinant Human Bone Morphogenetic Protein-2 with a Demineralized Bone Matrix versus Iliac Crest Bone Graft for Secondary Alveolar Bone Grafts in Patients with Cleft Lip and Palate: Review of 501 Cases Plast Reconstr Surg. 2017 Aug; 140(2):318e-325e. . View in PubMed

Early Cleft Lip Repair Revisited: A Safe and Effective Approach Utilizing a Multidisciplinary Protocol Plast Reconstr Surg Glob Open. 2017 Jun; 5(6):e1340. . View in PubMed

Familial Recurrence of 3MC Syndrome in Consanguineous Families: A Clinical and Molecular Diagnostic Approach With Review of the Literature Cleft Palate Craniofac J. 2017 11; 54(6):739-748. . View in PubMed

Surgical Management of Obstructive Sleep Apnea Plast Reconstr Surg. 2016 Apr; 137(4):1263-1272. . View in PubMed

Coping strategies and risk of cardiovascular disease incidence and mortality: the Japan Public Health Center-based prospective Study Eur Heart J. 2016 Mar 14; 37(11):890-899. . View in PubMed

Focusing Quality Improvement Initiatives in Pediatric Plastic Surgery: A Descriptive Study Using the Pediatric National Surgical Quality Improvement Program J Craniofac Surg. 2016 Mar; 27(2):277-81. . View in PubMed

Sutures Possess Strong Regenerative Capacity for Calvarial Bone Injury Stem Cells Dev. 2016 12 01; 25(23):1801-1807. . View in PubMed

Intracranial hypertension after surgical correction for craniosynostosis: a systematic review Neurosurg Focus. 2015 May; 38(5):E6. . View in PubMed

The suture provides a niche for mesenchymal stem cells of craniofacial bones Nat Cell Biol. 2015 Apr; 17(4):386-96. . View in PubMed

Natural large-scale regeneration of rib cartilage in a mouse model J Bone Miner Res. 2015 Feb; 30(2):297-308. . View in PubMed

Current Status of Surgical Planning for Orthognathic Surgery: Traditional Methods versus 3D Surgical Planning Plast Reconstr Surg Glob Open. 2015 Feb; 3(2):e307. . View in PubMed

Analysis of risk factors associated with microvascular free flap failure using a multi-institutional database Microsurgery. 2015 Jan; 35(1):6-12. . View in PubMed

A model for interprofessional health care: lessons learned from craniofacial teams J Calif Dent Assoc. 2014 Sep; 42(9):637-44. . View in PubMed

Assessment of three-dimensional high-definition visualization technology to perform microvascular anastomosis J Plast Reconstr Aesthet Surg. 2014 Jul; 67(7):967-72. . View in PubMed

Partial craniofacial duplication: a review of the literature and case report J Craniomaxillofac Surg. 2014 Jun; 42(4):290-6. . View in PubMed

Freeman-Sheldon syndrome and respiratory obstruction: a novel use of distraction osteogenesis J Craniofac Surg. 2014 May; 25(3):e287-9. . View in PubMed

Defining the role for submental intubation J Clin Anesth. 2014 May; 26(3):238-42. . View in PubMed

Simulation of plastic surgery and microvascular procedures using perfused fresh human cadavers J Plast Reconstr Aesthet Surg. 2014 Feb; 67(2):e42-8. . View in PubMed

TGFß regulates epithelial-mesenchymal interactions through WNT signaling activity to control muscle development in the soft palate Development. 2014 Feb; 141(4):909-17. . View in PubMed

Injectable gel graft for bone defect repair Regen Med. 2014 Jan; 9(1):41-51. . View in PubMed

Incorporation of fresh tissue surgical simulation into plastic surgery education: maximizing extraclinical surgical experience J Surg Educ. 2013 Jul-Aug; 70(4):466-74. . View in PubMed

rhBMP-2 with a demineralized bone matrix scaffold versus autologous iliac crest bone graft for alveolar cleft reconstruction Plast Reconstr Surg. 2013 May; 131(5):1107-1115. . View in PubMed

Paediatric presentation and outcome of congenital protein C deficiency in Japan Haemophilia. 2013 May; 19(3):378-84. . View in PubMed

Smad4-Irf6 genetic interaction and TGFß-mediated IRF6 signaling cascade are crucial for palatal fusion in mice Development. 2013 Mar; 140(6):1220-30. . View in PubMed

Scalp erosion in ankyloblepharon-ectodermal defect-cleft lip and/or palate (AEC syndrome): treatment with acellular dermal matrix J Craniofac Surg. 2013 Jan; 24(1):e28-30. . View in PubMed

Mandibular distraction instead of tracheostomy in Pierre Robin sequence patients: is it worth it? Plast Reconstr Surg. 2012 Nov; 130(5):766e-767e.. View in PubMed

Vector control in internal midface distraction using temporary anchorage devices J Craniofac Surg. 2012 Nov; 23(7 Suppl 1):2000-3. . View in PubMed

Multifocal lipoblastoma of the face J Craniofac Surg. 2012 Nov; 23(6):e585-7. . View in PubMed

The nance obturator, a new fixed obturator for patients with cleft palate and fistula J Prosthodont. 2012 Jul; 21(5):400-3. . View in PubMed

Solving convergent vector problems with internal maxillary distractors through the use of a fixed rapid palatal expander J Oral Maxillofac Surg. 2012 Jul; 70(7):e428-30. . View in PubMed

Modulation of noncanonical TGF-ß signaling prevents cleft palate in Tgfbr2 mutant mice J Clin Invest. 2012 Mar; 122(3):873-85. . View in PubMed

Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor ß (TGFß) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis J Biol Chem. 2012 Jan 20; 287(4):2353-63. . View in PubMed

Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups Clin Epidemiol. 2012; 4:187-91. . View in PubMed

Neonatal and infant mandibular distraction as an alternative to tracheostomy in severe obstructive sleep apnea Cleft Palate Craniofac J. 2012 Jan; 49(1):32-8. . View in PubMed

Nasofrontal heterotopic ossification following lymphangioma resection J Craniofac Surg. 2011 Nov; 22(6):2381-4. . View in PubMed

Delayed middle cranial fossa perforation after autologous temporomandibular joint reconstruction J Oral Maxillofac Surg. 2011 Jun; 69(6):1613-6. . View in PubMed

A mandibular mass in a pediatric patient J Oral Maxillofac Surg. 2011 Jun; 69(6):1661-7. . View in PubMed

Is presurgical nasoalveolar molding therapy more effective in unilateral or bilateral cleft lip-cleft palate patients? Plast Reconstr Surg. 2011 Mar; 127(3):1263-1269.. View in PubMed

Heteropagus (parasitic) twins: a review J Pediatr Surg. 2010 Dec; 45(12):2454-63. . View in PubMed

Adolescent orofacial injury: association with psychological symptoms Psychol Health Med. 2010 Oct; 15(5):574-83. . View in PubMed

Review of options for burned ear reconstruction J Craniofac Surg. 2010 Jul; 21(4):1165-9. . View in PubMed

TGF-beta mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue-tissue interactions during tongue morphogenesis Dev Biol. 2010 May 01; 341(1):186-95. . View in PubMed

Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells J Biol Chem. 2010 Feb 12; 285(7):4975-82. . View in PubMed

Misleading presentation of an orbital lymphangioma Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Feb; 109(2):e82-5. . View in PubMed

Factors associated with orofacial injury and willingness to participate in interventions among adolescents treated in trauma centers J Oral Maxillofac Surg. 2009 Dec; 67(12):2627-35. . View in PubMed

Recurrent and refractory giant cell tumor of the jaw J Craniofac Surg. 2009 Nov; 20(6):2245-8. . View in PubMed

Epithelial-specific requirement of FGFR2 signaling during tooth and palate development J Exp Zool B Mol Dev Evol. 2009 Jun 15; 312B(4):343-50. . View in PubMed

Bilateral complex odontomas: a rare complication of external mandibular distraction in the neonate J Craniofac Surg. 2009 May; 20(3):973-6. . View in PubMed

Clinical applications of orthodontic microimplant anchorage in craniofacial patients Cleft Palate Craniofac J. 2009 Mar; 46(2):136-46. . View in PubMed

Pneumosinus dilatans: a rare cause of frontal sinus expansion--case report and review of literature J Oral Maxillofac Surg. 2008 Nov; 66(11):2380-6. . View in PubMed

Amblyogenic anisometropia in the contralateral eye in unicoronal craniosynostosis J AAPOS. 2008 Oct; 12(5):471-6. . View in PubMed

Postoperative alopecia following orthognathic surgery J Oral Maxillofac Surg. 2008 Sep; 66(9):1957-8. . View in PubMed

Superior results using the islandized hemipalatal flap in palatoplasty: experience with 500 cases Plast Reconstr Surg. 2008 Jul; 122(1):232-239. . View in PubMed

TGF-beta signaling and aplasia cutis congenita: proposed animal model J Calif Dent Assoc. 2007 Dec; 35(12):865-9. . View in PubMed

Images in clinical medicineCocaine-induced palatal perforation. N Engl J Med. 2007 Nov 08; 357(19):1956. . View in PubMed

TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development Dev Biol. 2007 Oct 01; 310(1):140-53. . View in PubMed

A novel model surgery technique for LeFort III advancement J Craniofac Surg. 2007 Sep; 18(5):1230-5. . View in PubMed

Telogen effluvium following orthognathic surgery J Oral Maxillofac Surg. 2007 Jul; 65(7):1393-5. . View in PubMed

Facial nerve paralysis: a complication of distraction osteogenesis of the mandibular ramus in the treatment of temporomandibular joint ankylosis J Craniofac Surg. 2007 Jul; 18(4):844-8. . View in PubMed

Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion Dev Biol. 2006 Sep 01; 297(1):238-48. . View in PubMed

TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development Development. 2006 Jan; 133(2):371-81. . View in PubMed

Functional significance of Smad2 in regulating basal keratinocyte migration during wound healing J Invest Dermatol. 2005 Dec; 125(6):1302-9. . View in PubMed

The separation of Guatemalan craniopagus twins Childs Nerv Syst. 2004 Aug; 20(8-9):593-600. . View in PubMed

Multifocal papillary apocrine adenoma arising in a systematized linear epidermal nevus Cutis. 2004 May; 73(5):348-52. . View in PubMed

Median clefts of the upper lip: a review and surgical management of a minor manifestation J Craniofac Surg. 2003 09; 14(5):749-55. . View in PubMed

Confocal microscopic analysis of scarless repair in the fetal rat: defining the transition Plast Reconstr Surg. 2002 Jan; 109(1):160-70. . View in PubMed

Comparative evaluation of screw configuration on the stability of the sagittal split osteotomy Oral Surg Oral Med Oral Pathol. 1989 Aug; 68(2):125-9. . View in PubMed

Monoclonal antibody to the streptococcal preparation OK-432: tissue OK-432 localization and analysis of interaction between OK-432 and macrophages or NK cells in human salivary adenocarcinoma-bearing nude mice given OK-432 J Biol Response Mod. 1988 Apr; 7(2):212-28. . View in PubMed

An odontogenic myxofibroma related to an embedded third molar of the mandibleReport of a case. Int J Oral Surg. 1982 Aug; 11(4):265-9. . View in PubMed

Dr. Mark M. Urata is the Audrey Skirball-Kenis Chair and Chief of the Division of Plastic and Reconstructive Surgery of the Keck School of Medicine of USC. He is also Head of the Division of Plastic and Maxillofacial Surgery at Childrens Hospital Los Angeles and Director of Craniomaxillofacial Surgery at Cedars Sinai Medical Center. Dr. Urata is uniquely qualified with board certification in both Oral and Maxillofacial Surgery as well as Plastic Surgery and holds faculty appointments at both the Keck School of Medicine of USC and the USC School of Dentistry.
Dr. Urata trained for 18 years following his undergraduate education. He received his dental degree from the USC School of Dentistry and his medical degree from the USC Keck School of Medicine. He completed a residency in oral and maxillofacial surgery before matriculating to general surgery and then completing a residency in plastic and reconstructive surgery at USC. He then moved across town where he completed a fellowship in craniofacial surgery at the University of California, Los Angeles.

He specializes in the most complex craniofacial anomalies, including craniosynostosis, syndromic reconstruction, vascular anomalies, pediatric and adult craniomaxillofacial trauma, post-traumatic reconstruction, orthognathic surgery, aesthetic surgery of the head and neck and jaw deformities.

Dr. Urata has authored numerous scientific articles and book chapters and has been voted amongst the nation’s top surgeons according to multiple sources including U.S. News and World Report, Best Doctors and America’s Best Plastic Surgeons. He maintains NIH funded research within the Center for Craniofacial Molecular Biology related to defining TGF Beta signaling in palatogenesis. He is also interested in computerized planning of Le Fort III and orthognathic surgery and outcomes studies on cleft lip and palate.
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