Meredith N. Braskie, PhD

Assistant Professor of Neurology

INI Director of Education

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Overview

The Braskie lab seeks to gain a better understanding of risk factors for Alzheimer’s disease (AD), in particular, vascular and metabolic risk and inflammation. We do this by relating measures of multimodal imaging (structural and functional MRI, diffusion tensor imaging, and amyloid and tau PET) both to relevant blood and cerebrospinal fluid measures and to other medical and demographic data. We collaborate widely, including with wet labs that are researching similar topics.

Awards

  • Turken Award for Alzheimer’s Disease Research, 2011
  • 2009
     -: Ruth L. Kirschstein National Research Service Award, 2009
     – 2010
  • 2004
     -: Achievement Rewards for College Scientists (ARCS) fellowship, 2004
     – 2006
  • 2003
     -: Ruth L Kirschstein National Research Service Award, 2003
     – 2006
  • Bosco S. Tjan Mentorship Award, 2023

Education and Training

  • University of California, Los Angeles, Los Angeles, CA — PhD — Neuroscience
  • College of William and Mary, Williamsburg, VA — BBA

Research Funding

  • Alzheimer's Risk Intervention Trial with Estradiol (ARITE)
    NIH · R01AG102693 · Sep 1, 2026 – Aug 31, 2031 · Role: Co-Principal Investigator
  • Effect of diabetes and AD pathology on brain imaging and cognition in Latino adults
    NIH · R01AG078362 · Sep 30, 2022 – Aug 31, 2027 · Role: Co-Principal Investigator
  • Neurocognitive Aging & Analytics Research Education (NAARE)
    NIH · R25AG069711 · Jun 1, 2021 – May 31, 2026 · Role: Co-Principal Investigator
  • Hippocampal activity and pathology in APOE-4 subjects
    NIH · F31NS045425 · Sep 30, 2003 – Sep 29, 2006 · Role: Principal Investigator

Publications

  • Clinical-biological Alzheimer’s disease stage concordance: insights from cohorts and autopsy data. Brain. 2026 Aug 03; 149(8):2803-2815.. View in PubMed
  • Spatiotemporal dynamics of tau extent and load increase in Alzheimer’s disease across four longitudinal cohorts. Nat Aging. 2026 Jul; 6(7):1468-1481.. View in PubMed
  • Depression and hippocampal subfield volume in older adults. Transl Psychiatry. 2026 Jul 14.. View in PubMed
  • Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis. JAMA. 2026 Jul 13.. View in PubMed
  • Air pollution is linked to divergent cortical thickness patterns in brain regions vulnerable to Alzheimer’s disease. Neurotoxicology. 2026 Jul; 115:103495.. View in PubMed
  • CNS target engagement of high-dose DHA supplementation in older adults at risk for dementia: a randomised, double-blind, placebo-controlled trial. EBioMedicine. 2026 Jul; 129:106316.. View in PubMed
  • Race and Ethnicity, Hypertension, and Neuroimaging Markers of Brain Aging: A Causal Mediation Analysis in the HABS-HD Study. Neurology. 2026 Jul 14; 107(1):e218164.. View in PubMed
  • Eligibility for anti-amyloid treatment in a multiethnic community-based study. Alzheimers Dement (Amst). 2026 Apr-Jun; 18(2):e70314.. View in PubMed
  • Multimorbidity and Associations with Cognition and Alzheimer’s Disease Biomarkers. Ann Neurol. 2026 Aug; 100(2):370-379.. View in PubMed
  • Beyond Lipidation: CSF APOE4 Protein Burden, Not HDL Subclass, Drives Tau Associations in APOE4 Alzheimer’s Disease. Res Sq. 2026 Apr 24.. View in PubMed