Michael Chee-Kuan Khoo, PhD

Professor

Image of Michael Chee-Kuan Khoo, PhD
Is this your profile? Click to edit

Overview

Michael C.K. Khoo received his BSc(Eng) degree in Mechanical Engineering from the Imperial College of Science and Technology, University of London, in 1976, and the M.S. and Ph.D. degrees in Biomedical Engineering from Harvard University in 1977 and 1981, respectively. Before joining the faculty at USC in 1983, Dr. Khoo worked as a research engineer on a collaborative project involving the Veterans Administration Medical Center (West Roxbury), Brigham and Women’s Hospital (Boston) and the Massachusetts Institute of Technology. Dr. Khoo has been the recipient of a Research Career Development Award from the National Institutes of Health and a Career Investigator Award from the American Lung Association. He is principal investigator of one of the Core Projects in the Biomedical Simulations Resource, a national center funded by the NIH National Institute of Biomedical Imaging and Bioengineering, dedicated to advancing the state of the art in biomedical modeling and computer simulation. He is also the co-principal investigator of an NIH training grant in Biomedical Imaging Informatics, and co-Director of Education and Outreach for the NSF-funded Engineering Research Center on Biomimetic Microelectronic Systems. Dr. Khoo is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE) and the Biomedical Engineering Society (BMES). He was BME Department Chair 2003-2010.

Media

Publications

  • Towards automatic home screening of obstructive sleep apnea using combined features from pulse wave amplitude, pulse-to-pulse interval and oxygen desaturation. Sleep Breath. 2026 Feb 19; 30(1):57.. View in PubMed
  • Wearable Device Photoplethysmography As a Viable Tool to Longitudinally Monitor Vasoconstriction Biomarkers for Predicting Vaso-Occlusive Crisis in Sickle Cell Disease: Feasibility and Validation Study. JMIR Hum Factors. 2026 01 06; 13:e75465.. View in PubMed
  • Beat-to-beat analysis of hemodynamic response to mental and psychological stress in sickle cell anemia. J Sick Cell Dis. 2024; 1(1).. View in PubMed
  • Functional near-infrared spectroscopy-based prefrontal cortex oxygenation during working memory tasks in sickle cell disease. Neurophotonics. 2023 Oct; 10(4):045004.. View in PubMed
  • Treatment of Cheyne-Stokes Respiration in Heart Failure with Adaptive Servo-Ventilation: An Integrative Model. Adv Exp Med Biol. 2022; 1384:79-103.. View in PubMed
  • Respiratory modulation of peripheral vasoconstriction: a modeling perspective. J Appl Physiol (1985). 2019 11 01; 127(5):1177-1186.. View in PubMed
  • Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt. Front Physiol. 2019; 10:381.. View in PubMed
  • Quantifying ventilatory control stability from spontaneous sigh responses during sleep: a comparison of two approaches. Physiol Meas. 2018 11 22; 39(11):114005.. View in PubMed
  • Autonomic nervous system involvement in sickle cell disease. Clin Hemorheol Microcirc. 2018; 68(2-3):251-262.. View in PubMed
  • Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease. PLoS One. 2017; 12(5):e0178353.. View in PubMed