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Michael Goran, PhD

Professor of Pediatrics and Population and Public Health Sciences

Dr. Robert C. Atkins Chair in Childhood Obesity and Diabetes

Co-Director, Diabetes and Obesity Research Institute

Vice Chair of Research, Pediatrics

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Phone +1 323 442 3027
Email [email protected]
CTSI Profile

Research Funding

  • Understanding and Targeting the Pathophysiology of Youth-onset Type2 Diabetes
    NIH · U01DK134984 · Feb 21, 2023 – Jan 31, 2029 · Role: Principal Investigator
  • Southern California Center for Chronic Health Disparities in Latino Children and Families.
    NIH · P50MD017344 · Sep 24, 2021 – Jun 30, 2026 · Role: Principal Investigator
  • "Impact of Early feeding and human milk oligosaccharides on obesity and brain development".
    NIH · R01DK110793 · Apr 7, 2017 – May 31, 2025 · Role: Principal Investigator
  • Home intervention for reducing sugary drinks & obesity in Hispanic women-infants
    NIH · R01DK109161 · Sep 17, 2016 – Jun 30, 2022 · Role: Principal Investigator
  • Nutrigenetic Intervention to Reduce Liver Fat in Hispanics – Supplement
    NIH · R01MD010358 · Mar 24, 2016 – Nov 30, 2020 · Role: Principal Investigator
  • Obesity in Minority Youth in Los Angeles: A Generation "At Risk"
    NIH · P60MD002254 · Sep 11, 2007 – Apr 30, 2014 · Role: Principal Investigator
  • USC Center for Transdisciplinary Research on Energetics*
    NIH · U54CA116848 · Sep 19, 2005 – Aug 31, 2011 · Role: Principal Investigator
  • Type 2 Diabetes in Hispanic Adolescents
    NIH · R01DK059211 · Sep 30, 2000 – Feb 29, 2016 · Role: Principal Investigator
  • Intra-abdominal fat and risk of disease in adolescents
    NIH · R01HD033064 · Sep 18, 1996 – May 31, 2010 · Role: Principal Investigator
  • PREVENTION OF OBESITY IN CHILDREN
    NIH · R01HD032668 · Jun 15, 1994 – May 31, 2004 · Role: Principal Investigator
  • ENERGY EXPENDITURE DURING CHILDHOOD OBESITY DEVELOPMENT
    NIH · R29HD032668 · Jun 15, 1994 – May 31, 2000 · Role: Principal Investigator
  • DEVELOPMENT OF CHILDHOOD OBESITY
    NIH · R55HD028720 · Sep 30, 1992 – Jun 14, 1994 · Role: Principal Investigator

Publications

  • Ambient fine particulate matter components and liver fat and stiffness in youth: metabolic vulnerability in PNPLA3 risk carriers. Environ Int. 2026 Jul 25; 215:110438.. View in PubMed
  • Ultra-Processed Foods and Health Outcomes in Children and Adults: An Updated Narrative Umbrella Review With a Focus on Dose-Response. Nutr Rev. 2026 Jun 24.. View in PubMed
  • Early-Life Cumulative Intake of Ultra-Processed Foods and Subcortical Brain Volume at Age Six Years: A Prospective Cohort Study. Am J Clin Nutr. 2026 Jun 02; 101350.. View in PubMed
  • Carbohydrate composition of infant formula and glycemic regulation in early infancy using continuous glucose monitoring: cross-sectional evidence of altered glucose patterns with corn syrup solid-based formulas. Am J Clin Nutr. 2026 Jul; 124(1):101325.. View in PubMed
  • Evaluating Intra-household Agreement on Multi-domain Family-Level Social Determinants of Health and Exploring Individual Correlates of Agreement in Two Southern California Family Studies. Prev Sci. 2026 Apr; 27(4):571-581.. View in PubMed
  • Associations of prenatal fine particulate matter mixtures with neurodevelopmental outcomes in early childhood: component- and source-specific insights. Part Fibre Toxicol. 2026 Mar 01; 23(1).. View in PubMed
  • Specific Fat Depots and Cardiometabolic Risk and Insulin Resistance in Children With Obesity. Pediatr Obes. 2026 Mar; 21(3):e70097.. View in PubMed
  • Metabolites and proteins may mediate the relationship between diet quality and insulin sensitivity in young adult cohort. J Diabetes Metab Disord. 2026 Jun; 25(1):90.. View in PubMed
  • Maternal and Childhood Weight and Brain Structure in Children: Separate and Combined Associations in a Cross-Sectional Study. Obesity (Silver Spring). 2026 Mar; 34(3):699-709.. View in PubMed
  • Early-Life Air Pollution Exposure Is Associated with the Infant Gut Microbiome and Fecal Metabolome in the First Two Years of Life. Res Rep Health Eff Inst. 2026 Feb.. View in PubMed
  • Food and Drug Administration Expert Panel on Infant Formula “Operation Stork Speed” June 2025: Part 1, Nutrient Considerations. Adv Nutr. 2026 Apr; 17(4):100583.. View in PubMed
  • Food and Drug Administration Expert Panel on Infant Formula “Operation Stork Speed” June 2025: Part 3, Marketing of Infant Formulas, Breastfeeding Support, Hypoallergenic Formulas, and Nutrition for Preterm Infants. Adv Nutr. 2026 Apr; 17(4):100585.. View in PubMed
  • Food and Drug Administration Expert Panel on Infant Formula “Operation Stork Speed” June 2025: Part 2, Regulatory and Safety Considerations. Adv Nutr. 2026 Apr; 17(4):100584.. View in PubMed
  • Longer Breastfeeding Is Associated With Healthier Body Mass Index Trajectories and Lower Risk of Overweight and Obesity in Youth Aged 9-12 Years. Pediatr Obes. 2026 Jan; 21(1):e70082.. View in PubMed
  • Associations between per- and polyfluoroalkyl substances and metabolic dysfunction-associated steatotic liver disease in adolescents and young adults: modifying roles of age, lifestyle factors, and PNPLA3 genotype. Environ Res. 2026 Jan 01; 288(Pt 2):123320.. View in PubMed
  • Ultra-processed food intake is associated with altered glucose homeostasis in young adults with a history of overweight or obesity: a longitudinal study. Nutr Metab (Lond). 2025 Nov 10; 22(1):135.. View in PubMed
  • Mediating role of proteomics in the association between per- and polyfluoroalkyl substance exposure and blood pressure in youth. Environ Pollut. 2025 Dec 15; 387:127336.. View in PubMed
  • Social and Behavioral Factors Associated With Diabetes in Southern California vs the US. JAMA Netw Open. 2025 Oct 01; 8(10):e2538377.. View in PubMed
  • Social and Environmental Correlates of Childhood Obesity Among Southern California Communities. Obesity (Silver Spring). 2025 Nov; 33(11):2170-2180.. View in PubMed
  • Prenatal Nitrogen Oxide (NOx) and Its Potential Impact on Infant Metabolism during the First Month of Life: Evidence from Two Distinct Cohorts─The Atlanta African American Maternal-Child Cohort and the Southern California Mother’s Milk Study. Environ Sci Technol. 2025 Sep 16; 59(36):19131-19145.. View in PubMed
  • Assessing the Understanding of Chronic Diseases in the Latino Community of Southern California: A Qualitative Study. Am J Public Health. 2025 Jul; 115(S2):S126-S129.. View in PubMed
  • Ultra-Processed Food Intake is Associated with Altered Glucose Homeostasis in Young Adults. Res Sq. 2025 Jul 01.. View in PubMed
  • Chrome Plating Facility Siting Is Associated with Neighborhood Demographic and Socioeconomic Factors and Elevated Per- and Polyfluoroalkyl Substances in Blood in California. Environ Sci Technol. 2025 Jul 01; 59(25):12520-12532.. View in PubMed
  • Author Correction: The potential role of early life feeding patterns in shaping the infant fecal metabolome: implications for neurodevelopmental outcomes. NPJ Metab Health Dis. 2025 Jun 06; 3(1):23.. View in PubMed
  • Smaller Subcortical Volume in Reward Processing Regions Precedes Weight Gain in Youth With High Financial Adversity: Findings From the Adolescent Brain Cognitive Development Study. J Adolesc Health. 2025 Jul; 77(1):134-143.. View in PubMed
  • Sustained breastfeeding associations with brain structure and cognition from late childhood to early adolescence. Pediatr Res. 2025 Dec; 98(6):2144-2152.. View in PubMed
  • Corrigendum to “Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: a multicohort study” [Environ. Int 185 (2024) 108454]. Environ Int. 2025 May; 199:109520.. View in PubMed
  • Understanding the association of intrapancreatic fat deposition with adiposity and components of metabolic syndrome in children and adolescents: a systematic review and meta-analysis. EClinicalMedicine. 2025 May; 83:103205.. View in PubMed
  • Proteins and pathways involved in inflammation are longitudinally associated with total body bone mineral density among primarily Hispanic overweight/obese adolescents and young adults. J Bone Miner Res. 2025 Mar 15; 40(3):372-381.. View in PubMed
  • Factors that shape dietary intake in children in the context of increasing risk for obesity development. Pediatr Obes. 2025 Apr; 20(4):e70004.. View in PubMed
  • Efficacy of a 24-month behavioral intervention focused on sugary beverage reduction for Latino mother-infant dyads: evidence from a randomized controlled trial. Am J Clin Nutr. 2025 Feb; 121(2):355-366.. View in PubMed
  • Dihydroxyacetone phosphate is a novel predictor of hepatic fibrosis in Latino adolescents with obesity. J Pediatr Gastroenterol Nutr. 2025 Jan; 80(1):174-181.. View in PubMed
  • tRNA-derived RNAs in human milk extracellular vesicles and associations with breastfeeding variables and maternal diet. Epigenomics. 2024 Dec-Dec; 16(23-24):1429-1441.. View in PubMed
  • Associations between human milk EV-miRNAs and oligosaccharide concentrations in human milk. Front Immunol. 2024; 15:1463463.. View in PubMed
  • Examining disparities in PFAS plasma concentrations: Impact of drinking water contamination, food access, proximity to industrial facilities and superfund sites. Environ Res. 2025 Jan 01; 264(Pt 1):120370.. View in PubMed
  • Twenty-year trend in the prevalence of increased cardiometabolic risk, measured by abdominal obesity, among Spanish children and adolescents across body mass index categories. BMC Med. 2024 11 05; 22(1):509.. View in PubMed
  • Ambient air pollution exposure is associated with liver fat and stiffness in Latino youth with a more pronounced effect in those with PNPLA3 genotype and more advanced liver disease. Ecotoxicol Environ Saf. 2024 Nov 01; 286:117234.. View in PubMed
  • Effects of 8-h time-restricted eating on energy intake, dietary composition and quality in adolescents with obesity. Pediatr Obes. 2024 Nov; 19(11):e13165.. View in PubMed
  • Prenatal and Early Life Exposure to Ambient Air Pollutants Is Associated with the Fecal Metabolome in the First Two Years of Life. Environ Sci Technol. 2024 Aug 13; 58(32):14121-14134.. View in PubMed
  • Consumption of different combinations of human milk oligosaccharides in the first 6 mo of infancy is positively associated with early cognition at 2 y of age in a longitudinal cohort of Latino children. Am J Clin Nutr. 2024 09; 120(3):593-601.. View in PubMed
  • Effect of N-acetyl cysteine in children with metabolic dysfunction-associated steatotic liver disease-A pilot study. J Pediatr Gastroenterol Nutr. 2024 09; 79(3):652-660.. View in PubMed
  • Timing of Meal Consumption on Glucose Profiles in Latino Adolescents with Obesity. Horm Res Paediatr. 2025; 98(6):688-698.. View in PubMed
  • Maternal Diet Associated with Oligosaccharide Abundances in Human Milk from Latina Mothers. Nutrients. 2024 Jun 07; 16(12).. View in PubMed
  • The neighborhood food environment modifies the association between infant feeding and childhood obesity. BMC Public Health. 2024 05 08; 24(1):1264.. View in PubMed
  • Smaller subcortical volume relates to greater weight gain in girls with initially healthy weight. Obesity (Silver Spring). 2024 07; 32(7):1389-1400.. View in PubMed
  • Associations of dietary sugars with liver stiffness in Latino adolescents with obesity differ on PNPLA3 and liver disease severity. Liver Int. 2024 08; 44(8):1768-1774.. View in PubMed
  • Pre-pregnancy maternal obesity and infant neurodevelopmental outcomes in Latino infants. Obesity (Silver Spring). 2024 05; 32(5):979-988.. View in PubMed
  • Air pollution exposure may impact the composition of human milk oligosaccharides. Sci Rep. 2024 03 20; 14(1):6730.. View in PubMed
  • Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study. Environ Int. 2024 Mar; 185:108454.. View in PubMed
  • Any Infant Formula Amount, but Not Infant Formula Type, Is Associated with Less Healthful Subsequent Beverage Intake among Special Supplemental Nutrition Program for Women, Infants, and Children-Participating Children. Curr Dev Nutr. 2024 Mar; 8(3):102094.. View in PubMed
  • Proteomic and Metabolomic Signatures of Diet Quality in Young Adults. Nutrients. 2024 Jan 31; 16(3).. View in PubMed
  • Altered Nutrient Composition of Lactose-Reduced Infant Formula. Nutrients. 2024 Jan 17; 16(2).. View in PubMed
  • Postprandial Metabolite Profiles and Risk of Prediabetes in Young People: A Longitudinal Multicohort Study. Diabetes Care. 2024 01 01; 47(1):151-159.. View in PubMed
  • The potential role of early life feeding patterns in shaping the infant fecal metabolome: implications for neurodevelopmental outcomes. NPJ Metab Health Dis. 2023; 1.. View in PubMed
  • Endotoxin biomarkers, hepatic fat fraction, liver volume and liver stiffness among adolescents at high-risk for non-alcoholic fatty liver disease: The HEROES study. Pediatr Obes. 2024 02; 19(2):e13091.. View in PubMed
  • Exposure to perfluoroalkyl substances and longitudinal changes in bone mineral density in adolescents and young adults: A multi-cohort study. Environ Res. 2024 Mar 01; 244:117611.. View in PubMed
  • Characterizing alterations in the gut microbiota following postpartum weight change. mSystems. 2023 12 21; 8(6):e0080823.. View in PubMed
  • Randomized Controlled Feasibility Trial of Late 8-Hour Time-Restricted Eating for Adolescents With Type 2 Diabetes. J Acad Nutr Diet. 2024 08; 124(8):1014-1028.. View in PubMed
  • Sex-specific impulsivity, but not other facets of executive function, predicts fat and sugar intake two-years later amongst adolescents with a healthy weight: Findings from the ABCD study. Appetite. 2024 01 01; 192:107081.. View in PubMed
  • Variation in executive function relates to BMI increases in youth who were initially of a healthy weight in the ABCD Study. Obesity (Silver Spring). 2023 11; 31(11):2809-2821.. View in PubMed
  • Associations between Dietary Sugar and Fiber with Infant Gut Microbiome Colonization at 6 Mo of Age. J Nutr. 2024 01; 154(1):152-162.. View in PubMed
  • Effects of Low-Calorie Sweetener Restriction on Glycemic Variability and Cardiometabolic Health in Children with Type 1 Diabetes: Findings of a Pilot and Feasibility Study. Nutrients. 2023 Sep 05; 15(18).. View in PubMed
  • Effects of Dietary Sugar Reduction on Biomarkers of Cardiometabolic Health in Latino Youth: Secondary Analyses from a Randomized Controlled Trial. Nutrients. 2023 Jul 27; 15(15).. View in PubMed
  • Influence of technical and maternal-infant factors on the measurement and expression of extracellular miRNA in human milk. Front Immunol. 2023; 14:1151870.. View in PubMed
  • Human milk EV-miRNAs: a novel biomarker for air pollution exposure during pregnancy. Environ Res Health. 2023 Sep 01; 1(3):035002.. View in PubMed
  • Rapid Decline in β-Cell Function and Increasing Adiposity Are Associated With Conversion to Type 2 Diabetes in At-Risk Latino Youth. Diabetes. 2023 06 01; 72(6):735-745.. View in PubMed
  • Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop. Am J Clin Nutr. 2023 07; 118(1):329-337.. View in PubMed
  • Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway. JCI Insight. 2023 05 22; 8(10).. View in PubMed
  • Metabolic Signatures of Youth Exposure to Mixtures of Per- and Polyfluoroalkyl Substances: A Multi-Cohort Study. Environ Health Perspect. 2023 02; 131(2):27005.. View in PubMed
  • Longitudinal profiles of the fecal metabolome during the first 2 years of life. Sci Rep. 2023 02 02; 13(1):1886.. View in PubMed
  • Prenatal exposure to ambient air pollution is associated with neurodevelopmental outcomes at 2 years of age. Environ Health. 2023 01 24; 22(1):11.. View in PubMed
  • Stability of Human-Milk Oligosaccharide Concentrations Over 1 Week of Lactation and Over 6 Hours Following a Standard Meal. J Nutr. 2023 01 14; 152(12):2727-2733.. View in PubMed
  • The impact of social determinants of health on obesity and diabetes disparities among Latino communities in Southern California. BMC Public Health. 2023 01 06; 23(1):37.. View in PubMed
  • Micronutrient Profile and Carbohydrate Microstructure of Commercially Prepared and Home Prepared Infant Fruit and Vegetable Purees. Nutrients. 2022 Dec 22; 15(1).. View in PubMed
  • Complementary Feeding and Child Appetitive Traits in a Sample of Hispanic Mother-Child Dyads. J Acad Nutr Diet. 2023 09; 123(9):1340-1350.. View in PubMed
  • Lactose-reduced infant formula with corn syrup solids and obesity risk among participants in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). Am J Clin Nutr. 2022 10 06; 116(4):1002-1009.. View in PubMed
  • Associations of Human Milk Oligosaccharides with Infant Brain Tissue Organization and Regional Blood Flow at 1 Month of Age. Nutrients. 2022 Sep 16; 14(18).. View in PubMed
  • Diet Quality Is Associated with Glucose Regulation in a Cohort of Young Adults. Nutrients. 2022 Sep 10; 14(18).. View in PubMed
  • Clinical Intervention to Reduce Dietary Sugar Does Not Affect Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial. J Nutr. 2022 07 06; 152(7):1655-1665.. View in PubMed
  • Metabolome Alterations Linking Sugar-Sweetened Beverage Intake with Dyslipidemia in Youth: The Exploring Perinatal Outcomes among CHildren (EPOCH) Study. Metabolites. 2022 Jun 17; 12(6).. View in PubMed
  • Plasma concentrations of lipophilic persistent organic pollutants and glucose homeostasis in youth populations. Environ Res. 2022 09; 212(Pt B):113296.. View in PubMed
  • The Dose-Response Effects of Consuming High Fructose Corn Syrup-Sweetened Beverages on Hepatic Lipid Content and Insulin Sensitivity in Young Adults. Nutrients. 2022 Apr 15; 14(8).. View in PubMed
  • Adverse Effects of Infant Formula Made with Corn-Syrup Solids on the Development of Eating Behaviors in Hispanic Children. Nutrients. 2022 Mar 07; 14(5).. View in PubMed
  • Continuous Glucose Monitoring in Adolescents With Obesity: Monitoring of Glucose Profiles, Glycemic Excursions, and Adherence to Time Restricted Eating Programs. Front Endocrinol (Lausanne). 2022; 13:841838.. View in PubMed
  • Profile of Daughters and Sisters of Women With Polycystic Ovary Syndrome: The Role of Proband’s Glucose Tolerance. J Clin Endocrinol Metab. 2022 02 17; 107(3):e912-e923.. View in PubMed
  • Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration: a systematic review and intervention coding protocol. BMJ Open. 2022 Jan 20; 12(1):e048165.. View in PubMed
  • Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysis of behavioural interventions for the prevention of early childhood obesity. BMJ Open. 2022 Jan 20; 12(1):e048166.. View in PubMed
  • Postnatal exposure to ambient air pollutants is associated with the composition of the infant gut microbiota at 6-months of age. Gut Microbes. 2022 Jan-Dec; 14(1):2105096.. View in PubMed
  • Development and Validation of a Prediction Model for Infant Fat Mass. J Pediatr. 2022 04; 243:130-134.e2.. View in PubMed
  • Consuming Sucrose- or HFCS-sweetened Beverages Increases Hepatic Lipid and Decreases Insulin Sensitivity in Adults. J Clin Endocrinol Metab. 2021 10 21; 106(11):3248-3264.. View in PubMed
  • Time-Limited Eating and Continuous Glucose Monitoring in Adolescents with Obesity: A Pilot Study. Nutrients. 2021 Oct 21; 13(11).. View in PubMed
  • Associations of maternal non-nutritive sweetener intake during pregnancy with offspring body mass index and body fat from birth to adolescence. Int J Obes (Lond). 2022 01; 46(1):186-193.. View in PubMed
  • Risk of Micronutrient Inadequacy among Hispanic, Lactating Mothers: Preliminary Evidence from the Southern California Mother’s Milk Study. Nutrients. 2021 Sep 18; 13(9).. View in PubMed
  • Exposure to Perfluoroalkyl Substances and Glucose Homeostasis in Youth. Environ Health Perspect. 2021 09; 129(9):97002.. View in PubMed
  • Association of Prenatal Sugar Consumption with Newborn Brain Tissue Organization. Nutrients. 2021 Jul 16; 13(7).. View in PubMed
  • Prenatal exposure to ambient air pollutants and early infant growth and adiposity in the Southern California Mother’s Milk Study. Environ Health. 2021 06 05; 20(1):67.. View in PubMed
  • PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity. Nutrients. 2021 May 12; 13(5).. View in PubMed
  • Rationale and design of DRINK-T1D: A randomized clinical trial of effects of low-calorie sweetener restriction in children with type 1 diabetes. Contemp Clin Trials. 2021 07; 106:106431.. View in PubMed
  • Longitudinal Changes in Human Milk Oligosaccharides (HMOs) Over the Course of 24 Months of Lactation. J Nutr. 2021 04 08; 151(4):876-882.. View in PubMed
  • Ambient air pollutants are associated with morning serum cortisol in overweight and obese Latino youth in Los Angeles. Environ Health. 2021 04 08; 20(1):39.. View in PubMed

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