Michael Lansdell Paine, BSc, BDS, PhD

Professor of Dentistry

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Research Funding

Phosphate and Enamel Formation
NIH · R01DE034447 · Apr 10, 2025 – Jan 31, 2030 · Role: Principal Investigator
CRE MOUSE MODELS TO STUDY AMELOGENESIS
NIH · UH3DE028850 · Aug 1, 2021 – Jul 31, 2024 · Role: Principal Investigator
Amelogenesis and Ion Transport
NIH · R01DE029445 · Mar 15, 2021 – Feb 28, 2025 · Role: Principal Investigator
CRE MOUSE MODELS TO STUDY AMELOGENESIS
NIH · UG3DE028850 · Aug 1, 2019 – Jul 31, 2021 · Role: Principal Investigator
SODIUM-DEPENDENT PHOSPHATE TRANSPORTER FUNCTION IN ODONTOGENESIS
NIH · R21DE024704 · Mar 1, 2016 – Feb 28, 2019 · Role: Principal Investigator
Doctoral and Post-doctoral Training in Craniofacial Biology
NIH · R90DE022528 · Jul 1, 2011 – Jun 30, 2026 · Role: Principal Investigator
Doctoral and Post-doctoral Training in Craniofacial Biology
NIH · T90DE021982 · Jul 1, 2011 – Jun 30, 2026 · Role: Principal Investigator
MOLECULAR MECHANISMS FOR EXTRACELLULAR PH CONTROL DURING AMELOGENESIS
NIH · R01DE019629 · Sep 17, 2009 – Jun 30, 2016 · Role: Principal Investigator
TIP39KDA AND TOOTH FORMATION
NIH · R01DE014867 · Jul 1, 2003 – Jun 30, 2010 · Role: Principal Investigator
ENAMEL MATRIX PROTEIN INTERACTION
NIH · R01DE013404 · Mar 1, 2000 – Mar 31, 2014 · Role: Principal Investigator

A novel Ambn-IRESCre mouse line allows ameloblast-specific Smad4 silencing. Front Physiol. 2026; 17:1792453.. View in PubMed
Enamel Maturation as a Systems Physiology: Ion Transport and Pi Flux. Cells. 2025 11 20; 14(22).. View in PubMed
Pitx2-Sox2-Lef1 interactions specify progenitor oral/dental epithelial cell signaling centers. Development. 2020 06 04; 147(11).. View in PubMed
Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016. J Dent Res. 2018 05; 97(5):483-491.. View in PubMed
Bicarbonate Transport During Enamel Maturation. Calcif Tissue Int. 2017 11; 101(5):457-464.. View in PubMed
DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE. Physiol Rev. 2017 07 01; 97(3):939-993.. View in PubMed
Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells. Front Physiol. 2017; 8:336.. View in PubMed
Deletion of Slc26a1 and Slc26a7 Delays Enamel Mineralization in Mice. Front Physiol. 2017; 8:307.. View in PubMed
MiR-153 Regulates Amelogenesis by Targeting Endocytotic and Endosomal/lysosomal Pathways-Novel Insight into the Origins of Enamel Pathologies. Sci Rep. 2017 03 13; 7:44118.. View in PubMed
SLC26A Gene Family Participate in pH Regulation during Enamel Maturation. PLoS One. 2015; 10(12):e0144703.. View in PubMed