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Nancy Liu, MD

Assistant Professor of Research Orthopaedic Surgery

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Email [email protected]
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Overview

Dr. Nancy Q. Liu is an Assistant Professor of Research Orthopaedic Surgery at USC. Her research is mainly focused on understanding the mechanisms of chondrogenesis, articular chondrocytes maintenance and regeneration, and clinically relevant applications of stem cell and small molecule-based therapies for prevention of arthritis and restoration of damaged articular cartilage. She is involved in the development of various pre-clinical in vivo models for cartilage and bone repair. Dr. Liu is the author of numerous peer-reviewed research articles and presentations. She is also the reviewer for many scientific journals.

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Publications

  • GP130 Y814 SIGNALING IS REQUIRED FOR THE DYNAMIN-MEDIATED ENDOCYTOSIS, MAPK/P38 ACTIVATION AND PERSISTENCE OF CHRONIC SYSTEMIC INFLAMMATION INDUCED BY HIGH FAT DIET. bioRxiv. 2026 Feb 09.. View in PubMed
  • Pharmacological inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet. Sci Rep. 2024 12 28; 14(1):31151.. View in PubMed
  • MiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence. Arthritis Res Ther. 2024 05 29; 26(1):111.. View in PubMed
  • An injectable active hydrogel based on BMSC-derived extracellular matrix for cartilage regeneration enhancement. Biomater Adv. 2024 Jun; 160:213857.. View in PubMed
  • Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet. bioRxiv. 2024 Apr 11.. View in PubMed
  • Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis. Sci Transl Med. 2023 03 22; 15(688):eabq2395.. View in PubMed
  • STAT3 promotes a youthful epigenetic state in articular chondrocytes. Aging Cell. 2023 02; 22(2):e13773.. View in PubMed
  • A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification. Front Cell Dev Biol. 2022; 10:954028.. View in PubMed
  • Author Correction: gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes. Commun Biol. 2022 Feb 25; 5(1):200.. View in PubMed
  • gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes. Commun Biol. 2022 01 17; 5(1):64.. View in PubMed

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