Niels Kokot, MD

Professor of Clinical Otolaryngology-Head & Neck Surgery

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Niels Kokot, MD, serves as professor of otolaryngology and the residency program director in the Department of Otolaryngology, Head and Neck Surgery.

Dr. Kokot is trained in Transoral Robotic Surgery (TORS), a minimally invasive technique allowing for the treatment of many head and neck tumors without requiring traditional open approaches.

Dr. Kokot’s clinical specialties encompass all aspects of head and neck surgery, including the management of tumors in the oral cavity, larynx, pharynx, skull base, salivary glands, and thyroid gland, as well as microvascular surgery. He has a particular interest in conservation surgery of the larynx, which is designed to treat cancers of the larynx (voice box) without sacrificing speech or requiring permanent tracheostomy.

USC Caruso Department of Otolaryngology – Head & Neck Surgery


  • Pasadena Magazine: Top Doctor, 2011-2015


  • Evaluation of Oropharyngeal Cancer Information from Revolutionary Artificial Intelligence Chatbot Laryngoscope. 2024 May; 134(5):2252-2257. . View in PubMed
  • Influence of Anatomic Locations of T1b Melanomas and Patient Age on Outcomes J Drugs Dermatol. 2024 May 01; 23(5):306-310. . View in PubMed
  • In Response to Evaluation of Oropharyngeal Cancer Information from Revolutionary Artificial Intelligence Chatbot Laryngoscope. 2024 May; 134(5):E19. . View in PubMed
  • Associations Between Risk Perception and HPV Knowledge and Vaccine Uptake: Highlighting the LGBTQ+ Population Otolaryngol Head Neck Surg. 2024 Feb 08. . View in PubMed
  • Cost-Effectiveness Analysis of PET-CT Surveillance After Treatment of Human Papillomavirus-Positive Oropharyngeal Cancer Otolaryngol Head Neck Surg. 2024 Jan; 170(1):122-131. . View in PubMed
  • Differences in presentation, treatment, and outcomes among minority head and neck cancer patient groups in Los Angeles County Am J Otolaryngol. 2024 Jan-Feb; 45(1):104031. . View in PubMed
  • Assessing Laryngectomy Patient Education on YouTube: Investigating Quality and Reliability OTO Open. 2024 Jan-Mar; 8(1):e113. . View in PubMed
  • Free Flap Outcomes for Head and Neck Surgery in Patients with COVID-19 Laryngoscope. 2023 Nov 08. . View in PubMed
  • Managing Bethesda IV thyroid nodules in an iodine-deficient population Gland Surg. 2023 Oct 30; 12(10):1332-1335. . View in PubMed
  • Head and Neck Cancer Online Support Groups: Disparities in Participation and Impact on Patients OTO Open. 2023 Oct-Dec; 7(4):e87. . View in PubMed
  • Ameloblastoma of the Mandible With Carcinoma Transformation in a Young Adult Ear Nose Throat J. 2023 May 09; 1455613231172857. . View in PubMed
  • Comparison of Free Flap Outcomes at a University Hospital versus County Hospital Setting for Head and Neck Reconstruction Int Arch Otorhinolaryngol. 2023 Apr; 27(2):e183-e190. . View in PubMed
  • Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma N Engl J Med. 2023 Mar 02; 388(9):813-823. . View in PubMed
  • The effects of psychosocial determinants on post-operative complications of head and neck free flap patients Am J Otolaryngol. 2023 Mar-Apr; 44(2):103721. . View in PubMed
  • Open Bedside Tracheostomy: Safe and Cost Saving but Underutilized Nationally Otolaryngol Head Neck Surg. 2023 02; 168(2):188-195. . View in PubMed
  • Variations of the trapezius branch of the accessory nerve: an anatomic study Sci Rep. 2023 12 15; 13(1):22369. . View in PubMed
  • Opioid Sparing Multimodal Analgesia for Transoral Robotic Surgery: Improved Analgesia and Narcotic Use Reduction OTO Open. 2023 Jan-Mar; 7(1):e17. . View in PubMed
  • Jehovah’s witness head and neck free flap reconstruction patient outcomes Am J Otolaryngol. 2023 Jan-Feb; 44(1):103681. . View in PubMed
  • Human papillomavirus detection in oral rinses and history of tonsillectomy in US. adults. Am J Otolaryngol. 2022 Nov-Dec; 43(6):103558. . View in PubMed
  • Association of patient characteristics, ultrasound features, and molecular testing with malignancy risk in Bethesda III-V thyroid nodules Laryngoscope Investig Otolaryngol. 2022 Aug; 7(4):1243-1250. . View in PubMed
  • Use of ICG Angiography in Head and Neck Reconstruction With the Supraclavicular Artery Island Flap J Oral Maxillofac Surg. 2022 08; 80(8):1424-1433. . View in PubMed
  • Cost-effectiveness Analysis of Submandibular Gland Preservation With Sialendoscopy for the Management of Sialolithiasis Otolaryngol Head Neck Surg. 2022 04; 166(4):662-668. . View in PubMed
  • Supraclavicular Artery Island Flap: Critical Appraisal and Comparison to Alternate Reconstruction Laryngoscope. 2022 02; 132 Suppl 3:1-14. . View in PubMed
  • PD-1 inhibition therapy for advanced cutaneous squamous cell carcinoma: a retrospective analysis from the University of Southern California J Cancer Res Clin Oncol. 2021 Jun; 147(6):1803-1811. . View in PubMed
  • Targeted Wellness Initiatives Are Most Effective for Reducing Otolaryngology Resident Burnout Ear Nose Throat J. 2021 Apr 13; 1455613211009139. . View in PubMed
  • Outcomes of Combined Antegrade-Retrograde Dilations for Radiation-Induced Esophageal Strictures in Head and Neck Cancer Patients Dysphagia. 2021 12; 36(6):1040-1047. . View in PubMed
  • Trends in Operative Complex Middle and Upper Maxillofacial Trauma: A 17-Year Study Laryngoscope. 2021 09; 131(9):1985-1989. . View in PubMed
  • Risk Factors for Plate Extrusion After Mandibular Reconstruction With Vascularized Free Flap J Oral Maxillofac Surg. 2021 08; 79(8):1760-1768. . View in PubMed
  • ERAS for Head and Neck Tissue Transfer Reduces Opioid Usage, Peak Pain Scores, and Blood Utilization Laryngoscope. 2021 03; 131(3):E792-E799. . View in PubMed
  • Response to Letter to the Editor Regarding “Reconstruction After Salvage Total Laryngectomy: A Cost-effectiveness Analysis” Otolaryngol Head Neck Surg. 2021 02; 164(2):453-454. . View in PubMed
  • Squamous Cell Carcinoma Metastasis to the Supraclavicular Artery Island Flap Donor Site Laryngoscope. 2021 02; 131(2):E440-E442. . View in PubMed
  • Reconstruction After Salvage Total Laryngectomy: A Cost-effectiveness Analysis Otolaryngol Head Neck Surg. 2021 01; 164(1):139-145. . View in PubMed
  • Prevalence of oral human papillomavirus infections by race in the United States: An association with sexual behavior Oral Dis. 2020 Jul; 26(5):930-940. . View in PubMed
  • Enhanced Recovery After Surgery-Based Perioperative Protocol for Head and Neck Free Flap Reconstruction OTO Open. 2020 Apr-Jun; 4(2):2473974X20931037. . View in PubMed
  • Complete response with talimogene laherparepvec in recurrent melanoma of the ear: A case report Oral Oncol. 2020 12; 111:104899. . View in PubMed
  • Association of insurance type with time course of care in head and neck cancer management Laryngoscope. 2020 11; 130(11):E587-E592. . View in PubMed
  • Evaluation of lymph node ratio and lymph node yield as prognosticators of locoregional recurrence in p16-associated oropharyngeal squamous cell carcinoma Head Neck. 2020 10; 42(10):2811-2820. . View in PubMed
  • A Practical Mathematic Method to Predict and Manage Hypocalcemia After Parathyroidectomy and Thyroidectomy Ann Otol Rhinol Laryngol. 2020 Jan; 129(1):70-77. . View in PubMed
  • Association of Race/Ethnicity, Stage, and Survival in Oral Cavity Squamous Cell Carcinoma: A SEER Study OTO Open. 2019 Oct-Dec; 3(4):2473974X19891126. . View in PubMed
  • Trends in Diagnostic Flexible Laryngoscopy and Videolaryngostroboscopy Utilization in the US Medicare Population JAMA Otolaryngol Head Neck Surg. 2019 Aug 01; 145(8):716-722. . View in PubMed
  • Outcomes of Self-Esophageal Dilation for Head and Neck Cancer Patients Am J Speech Lang Pathol. 2019 08 09; 28(3):1060-1066. . View in PubMed
  • Outcomes of reconstruction after temporal bone resection for malignancy J Craniomaxillofac Surg. 2018 Oct; 46(10):1856-1861. . View in PubMed
  • EC-IC bypass for cerebral revascularization following skull base tumor resection: Current practices and innovations J Surg Oncol. 2018 Oct; 118(5):815-825. . View in PubMed
  • The molecular mechanisms of increased radiosensitivity of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC): an extensive review J Otolaryngol Head Neck Surg. 2018 Sep 21; 47(1):59. . View in PubMed
  • Hypothyroidism Potentially Linked to Cutaneous Squamous Cell Carcinoma: Retrospective Study at a Single Tertiary Academic Medical Center Dermatol Surg. 2018 Jan; 44(1):10-16. . View in PubMed
  • Clin Med Insights Ear Nose Throat. 2018; 11:1179550618792248. . View in PubMed
  • Reconstruction of parotidectomy and lateral skull base defects Curr Opin Otolaryngol Head Neck Surg. 2017 Oct; 25(5):431-438. . View in PubMed
  • Transoral surgery vs intensity-modulated radiotherapy for early supraglottic cancer: a systematic review Curr Opin Otolaryngol Head Neck Surg. 2017 Apr; 25(2):133-141. . View in PubMed
  • Scapular osteocutaneous free flap for total lower lip and mandible reconstruction Microsurgery. 2016 Sep; 36(6):480-4. . View in PubMed
  • Device Life of Two Generations of Provox Voice Prostheses Ann Otol Rhinol Laryngol. 2016 Jun; 125(6):501-7. . View in PubMed
  • The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis Cancers (Basel). 2016 Feb 19; 8(2). . View in PubMed
  • ABCLOVE: Voice therapy outcomes for patients with head and neck cancer Head Neck. 2016 04; 38 Suppl 1:E1810-3. . View in PubMed
  • Pigmented villonodular synovitis of the temporomandibular joint: Case report and review of the literature Head Neck. 2015 Dec; 37(12):E194-9. . View in PubMed
  • Use of Octreotide for the Management of Chyle Fistula Following Neck Dissection JAMA Otolaryngol Head Neck Surg. 2015 Aug; 141(8):723-7. . View in PubMed
  • Hypopharyngeal hemangioma in an adult: a case report Ear Nose Throat J. 2014 Oct-Nov; 93(10-11):E26-8. . View in PubMed
  • Bacterial biofilms and increased bacterial counts are associated with airway stenosis Otolaryngol Head Neck Surg. 2014 May; 150(5):834-40. . View in PubMed
  • Use of the supraclavicular artery island flap for reconstruction of cervicofacial defects Otolaryngol Head Neck Surg. 2014 Feb; 150(2):222-8. . View in PubMed
  • The supraclavicular artery island flap in head and neck reconstruction: applications and limitations JAMA Otolaryngol Head Neck Surg. 2013 Nov; 139(11):1247-55. . View in PubMed
  • Transoral robotic resection of oropharyngeal synovial sarcoma in a pediatric patient Int J Pediatr Otorhinolaryngol. 2013 Jun; 77(6):1042-4. . View in PubMed
  • Immune cell infiltration patterns and survival in head and neck squamous cell carcinoma Head Neck Oncol. 2013 Feb 27; 5(3):24. . View in PubMed
  • Radiology quiz case 2Iatrogenic ectopic thyroid. JAMA Otolaryngol Head Neck Surg. 2013 Feb; 139(2):189-91. . View in PubMed
  • Reconstruction of total lower eyelid defects with the temporoparietal fascial flap Case Rep Ophthalmol Med. 2012; 2012:927260. . View in PubMed
  • Split central venous sampling of parathyroid hormone: an adjunct to surgical exploration Head Neck. 2011 Dec; 33(12):1715-8. . View in PubMed
  • CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function J Exp Med. 2002 Jun 03; 195(11):1407-18. . View in PubMed
  • Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation J Neurosci. 2001 Jul 01; 21(13):4657-67. . View in PubMed
  • Macrophage activation by polycyclic aromatic hydrocarbons: evidence for the involvement of stress-activated protein kinases, activator protein-1, and antioxidant response elements J Immunol. 1998 Jul 15; 161(2):942-51. . View in PubMed
  • Inflammatory cytokines induce the expression of basic fibroblast growth factor (bFGF) isoforms required for the growth of Kaposi’s sarcoma and endothelial cells through the activation of AP-1 response elements in the bFGF promoter AIDS. 1998 Jan 01; 12(1):19-27. . View in PubMed
  • The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression J Immunol. 1998 Jan 01; 160(1):134-44. . View in PubMed
  • Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cellsEvidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation. J Biol Chem. 1996 Nov 01; 271(44):27366-73. . View in PubMed