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Nils Lindstrom

Assistant Professor of Stem Cell and Regenerative Medicine

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Phone +1 323 442 0564
Email [email protected]
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Publications

  • Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling. Cell Stem Cell. 2025 Oct 02; 32(10):1614-1633.e13.. View in PubMed
  • Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development. Dev Cell. 2024 11 04; 59(21):2912-2930.e7.. View in PubMed
  • Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15; 151(18).. View in PubMed
  • Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease. Cell Stem Cell. 2024 Jun 06; 31(6):921-939.e17.. View in PubMed
  • Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Dev Biol. 2020 02 15; 458(2):164-176.. View in PubMed
  • Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Dev Cell. 2019 11 04; 51(3):399-413.e7.. View in PubMed
  • In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev Cell. 2019 07 01; 50(1):102-116.e6.. View in PubMed
  • Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions. Am J Kidney Dis. 2019 01; 73(1):140-142.. View in PubMed
  • Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018 12 05; 7.. View in PubMed
  • Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Dev Cell. 2018 06 04; 45(5):651-660.e4.. View in PubMed
  • Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. J Am Soc Nephrol. 2018 03; 29(3):825-840.. View in PubMed
  • Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J Am Soc Nephrol. 2018 03; 29(3):785-805.. View in PubMed
  • Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. J Am Soc Nephrol. 2018 03; 29(3):806-824.. View in PubMed
  • The developmental and genetic basis of ‘clubfoot’ in the peroneal muscular atrophy mutant mouse. Development. 2018 02 08; 145(3).. View in PubMed
  • Deducing the stage of origin of Wilms’ tumours from a developmental series of Wt1-mutant mice. Dis Model Mech. 2015 Aug 01; 8(8):903-17.. View in PubMed
  • The PI3K pathway balances self-renewal and differentiation of nephron progenitor cells through β-catenin signaling. Stem Cell Reports. 2015 Apr 14; 4(4):551-60.. View in PubMed
  • Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron. Elife. 2015 Feb 03; 3:e04000.. View in PubMed
  • Node retraction during patterning of the urinary collecting duct system. J Anat. 2015 Jan; 226(1):13-21.. View in PubMed
  • Fucci2a: a bicistronic cell cycle reporter that allows Cre mediated tissue specific expression in mice. Cell Cycle. 2014; 13(17):2681-96.. View in PubMed
  • Nephrons require Rho-kinase for proximal-distal polarity development. Sci Rep. 2013; 3:2692.. View in PubMed
  • Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis. Gene Expr Patterns. 2011 Mar-Apr; 11(3-4):221-32.. View in PubMed
  • Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells. Am J Physiol Renal Physiol. 2010 Oct; 299(4):F740-51.. View in PubMed
  • Developmental plasticity and regenerative capacity in the renal ureteric bud/collecting duct system. Development. 2008 Aug; 135(15):2505-10.. View in PubMed

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