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Nitin Pandey, PhD

Assistant Professor of Research Physiology and Neuroscience

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Email [email protected]
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Education and Training

  • Indian Institute of Technology, Kharagpur — PhD — 07/2014 — Biophysics

Publications

  • Pectinase-Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development. Biotechnol Bioeng. 2026 Jul 30.. View in PubMed
  • TDP43 and huntingtin Exon-1 undergo a conformationally specific interaction that strongly alters the fibril formation of both proteins. J Biol Chem. 2024 09; 300(9):107660.. View in PubMed
  • Fluorescent protein tagging promotes phase separation and alters the aggregation pathway of huntingtin exon-1. J Biol Chem. 2024 01; 300(1):105585.. View in PubMed
  • Amplification of neurotoxic HTTex1 assemblies in human neurons. Neurobiol Dis. 2021 11; 159:105517.. View in PubMed
  • Huntingtin fibrils with different toxicity, structure, and seeding potential can be interconverted. Nat Commun. 2021 07 13; 12(1):4272.. View in PubMed
  • Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells. ACS Chem Neurosci. 2020 08 05; 11(15):2286-2295.. View in PubMed
  • Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms. Structure. 2019 10 01; 27(10):1570-1580.e4.. View in PubMed
  • Lipid-modulation of membrane insertion and refolding of the apoptotic inhibitor Bcl-xL. Biochim Biophys Acta Proteins Proteom. 2019 Jul – Aug; 1867(7-8):691-700.. View in PubMed
  • The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract. J Biol Chem. 2018 12 21; 293(51):19613-19623.. View in PubMed
  • Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin. Hum Mol Genet. 2018 07 01; 27(13):2330-2343.. View in PubMed

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