Keck School Faculty

Omid Akbari, PhD
Omid Akbari, PhD
Professor of Molecular Microbiology & Immunology
Molecular Microbiology and Immunology
NRT 5505 1450 Biggy Street Health Sciences Campus Los Angeles

Roles of Type 1, 2, and 3 Innate Lymphoid Cells in Herpes Simplex Virus 1 Infection In Vitro and In Vivo J Virol. 2019 Jul 01; 93(13). . View in PubMed

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes Nat Commun. 2019 Feb 12; 10(1):713. . View in PubMed

Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice Sci Rep. 2019 Feb 12; 9(1):1816. . View in PubMed

Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance Nat Commun. 2019 04 12; 10(1):1693. . View in PubMed

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes Nat Commun. 2019 02 12; 10(1):713. . View in PubMed

Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentationJ Allergy Clin Immunol. 2018 Dec; 142(6):1894-1908. e7. . View in PubMed

Herpes Simplex Virus 1 Specifically Targets Human CD1d Antigen Presentation To Enhance Its Pathogenicity J Virol. 2018 Nov 15; 92(22). . View in PubMed

Herpes simplex virus-1 specifically targets human CD1d antigen presentation to enhance its pathogenicity J Virol. 2018 Sep 05. . View in PubMed

Activated plasmacytoid dendritic cells regulate type 2 innate lymphoid cell-mediated airway hyperreactivityJ Allergy Clin Immunol. 2018 Mar; 141(3):893-905. e6. . View in PubMed

IL-10, TGF-ß, and glucocorticoid prevent the production of type 2 cytokines in human group 2 innate lymphoid cellsJ Allergy Clin Immunol. 2018 Mar; 141(3):1147-1151. e8. . View in PubMed

Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation J Allergy Clin Immunol. 2018 Feb 20. . View in PubMed

Social Networking of Group Two Innate Lymphoid Cells in Allergy and Asthma Front Immunol. 2018; 9:2694. . View in PubMed

Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator-inducible T-cell costimulator ligand interactionJ Allergy Clin Immunol. 2017 May; 139(5):1468-1477. e2. . View in PubMed

Reply J Allergy Clin Immunol. 2017 Feb; 139(2):712-713. . View in PubMed

Group 2 innate lymphoid cells are elevated and activated in chronic rhinosinusitis with nasal polyps Immun Inflamm Dis. 2017 09; 5(3):233-243. . View in PubMed

Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation Antimicrob Agents Chemother. 2017 08; 61(8). . View in PubMed

Type two innate lymphoid cells: the Janus cells in health and disease Immunol Rev. 2017 07; 278(1):192-206. . View in PubMed

Reply J Allergy Clin Immunol. 2017 02; 139(2):712-713. . View in PubMed

Increased Innate Lymphoid Cells in Periodontal Tissue of the Murine Model of Periodontitis: The Role of AMP-Activated Protein Kinase and Relevance for the Human Condition Front Immunol. 2017; 8:922. . View in PubMed

Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity Nat Commun. 2016 Oct 18; 7:13202. . View in PubMed

Innate lymphoid cells: a paradigm for low SSI in cleft lip repair J Surg Res. 2016 Oct; 205(2):312-317. . View in PubMed

Lack of autophagy induces steroid-resistant airway inflammationJ Allergy Clin Immunol. 2016 May; 137(5):1382-1389. e9. . View in PubMed

Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):172-80. . View in PubMed

Innate lymphoid cells: a paradigm for low SSI in cleft lip repair J Surg Res. 2016 10; 205(2):312-317. . View in PubMed

Lower omental t-regulatory cell count is associated with higher fasting glucose and lower ß-cell function in adults with obesity Obesity (Silver Spring). 2016 06; 24(6):1274-82. . View in PubMed

Lack of autophagy induces steroid-resistant airway inflammationJ Allergy Clin Immunol. 2016 05; 137(5):1382-1389. e9. . View in PubMed

Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity Nat Commun. 2016 10 18; 7:13202. . View in PubMed

Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4 J Neuroimmunol. 2016 10 15; 299:70-78. . View in PubMed

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission Immunity. 2016 05 17; 44(5):1204-14. . View in PubMed

Cell Rep. 2016 07 12; 16(2):405-418. . View in PubMed

ICOS regulates ILC2s in asthma Oncotarget. 2015 Sep 22; 6(28):24584-5. . View in PubMed

A Subset of CD8aß+ Invariant NKT Cells in a Humanized Mouse Model J Immunol. 2015 Aug 15; 195(4):1459-69. . View in PubMed

Batf3 deficiency is not critical for the generation of CD8a? dendritic cells. Immunobiology. 2015 Apr; 220(4):518-24.. View in PubMed

ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity Immunity. 2015 Mar 17; 42(3):538-51. . View in PubMed

Inclusion of CD80 in HSV targets the recombinant virus to PD-L1 on DCs and allows productive infection and robust immune responses PLoS One. 2014; 9(1):e87617. . View in PubMed

Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivityJ Allergy Clin Immunol. 2013 Apr; 131(4):1048-57, 1057. e1-2. . View in PubMed

Sex-specific perinatal nicotine-induced asthma in rat offspring Am J Respir Cell Mol Biol. 2013 Jan; 48(1):53-62. . View in PubMed

Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection PLoS One. 2013; 8(3):e59599. . View in PubMed

Perinatal nicotine exposure induces asthma in second generation offspring BMC Med. 2012 Oct 30; 10:129. . View in PubMed

Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties J Immunol. 2012 Mar 01; 188(5):2254-65. . View in PubMed

Effects of systemic versus local administration of corticosteroids on mucosal tolerance J Immunol. 2012 Jan 01; 188(1):470-6. . View in PubMed

Epithelium-specific deletion of TGF-ß receptor type II protects mice from bleomycin-induced pulmonary fibrosis J Clin Invest. 2011 Jan; 121(1):277-87. . View in PubMed

TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells J Immunol. 2010 Dec 01; 185(11):6839-49. . View in PubMed

A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity J Immunol. 2010 Feb 15; 184(4):2107-15. . View in PubMed

PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions Mucosal Immunol. 2010 Jan; 3(1):81-91. . View in PubMed

The role of costimulatory molecules in allergic disease and asthma Int Arch Allergy Immunol. 2010; 151(3):179-89. . View in PubMed

Dendritic cell modulation as a new interventional approach for the treatment of asthma Drug News Perspect. 2009 Oct; 22(8):445-51. . View in PubMed

Natural killer T cells in the lungs of patients with asthma J Allergy Clin Immunol. 2009 May; 123(5):1181-5. . View in PubMed

Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB J Immunol. 2009 Apr 15; 182(8):5116-22. . View in PubMed

Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta 2-microglobulin-deficient mice J Immunol. 2008 Oct 01; 181(7):4560-4569. . View in PubMed

Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR alpha-chain CDR3 loop Eur J Immunol. 2008 Jun; 38(6):1756-66. . View in PubMed

ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival J Immunol. 2008 Apr 15; 180(8):5448-56. . View in PubMed

Recent advances in the role of NKT cells in allergic diseases and asthma Curr Allergy Asthma Rep. 2008 Apr; 8(2):165-70. . View in PubMed

Invariant natural killer T cells in obstructive pulmonary diseases N Engl J Med. 2007 Jul 12; 357(2):193-4; author reply 194-5. . View in PubMed

CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma N Engl J Med. 2006 Mar 16; 354(11):1117-29. . View in PubMed

Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2782-7. . View in PubMed

Respiratory tolerance is inhibited by the administration of corticosteroids J Immunol. 2005 Dec 01; 175(11):7380-7. . View in PubMed

TIM-1 induces T cell activation and inhibits the development of peripheral tolerance Nat Immunol. 2005 May; 6(5):447-54. . View in PubMed

Role of regulatory dendritic cells in allergy and asthma Curr Allergy Asthma Rep. 2005 Jan; 5(1):56-61. . View in PubMed

Role of regulatory dendritic cells in allergy and asthma Curr Opin Allergy Clin Immunol. 2004 Dec; 4(6):533-8. . View in PubMed

Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity Nat Immunol. 2004 Nov; 5(11):1149-56. . View in PubMed

CD8(+) T cells regulate immune responses in a murine model of allergen-induced sensitization and airway inflammation Eur J Immunol. 2004 Jul; 34(7):1817-27. . View in PubMed

Role of regulatory T cells in allergy and asthma Curr Opin Immunol. 2003 Dec; 15(6):627-33. . View in PubMed

Regulatory T cells control the development of allergic disease and asthma J Allergy Clin Immunol. 2003 Sep; 112(3):480-7; quiz 488. . View in PubMed

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity Nat Med. 2003 May; 9(5):582-8. . View in PubMed

Mucosal tolerance and immunity: regulating the development of allergic disease and asthma Int Arch Allergy Immunol. 2003 Feb; 130(2):108-18. . View in PubMed

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity Nat Med. 2002 Sep; 8(9):1024-32. . View in PubMed

CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation J Allergy Clin Immunol. 2002 Sep; 110(3):460-8. . View in PubMed

Asthma: an epidemic of dysregulated immunity Nat Immunol. 2002 Aug; 3(8):715-20. . View in PubMed

Powered by SC CTSI
Go to Top