Peck Y. Ong, MD

Associate Professor of Clinical Pediatrics

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Overview

Peck Ong, MD, is Associate Professor of Clinical Pediatrics at University of Southern California. He is a diplomate of the American Board of Allergy and Immunology. Dr. Ong specializes in atopic dermatitis (eczema), food allergy and asthma. He has written multiple research and review articles on these topics. Most notable is his New England Journal of Medicine paper that showed low defensin level in atopic dermatitis patients. This paper remains one of the most cited papers in atopic dermatitis. Dr. Ong is the site Principal Investigator for Atopic Dermatitis Research Network in Los Angeles. Many children with atopic dermatitis also have food allergy or asthma. He is combining his knowledge in the latest research and clinical experience to solve these problems. To contact Dr. Ong’s Arcadia office Phone: 626-795-7177 Fax: 626-357-4052

Publications

  • Therapeutic applications of germline testing for cancer predisposition genes in Asia in the real world ESMO Open. 2024 Jun; 9(6):103482. . View in PubMed
  • Emerging drugs for the treatment of atopic dermatitis: a focus on phase 2 and phase 3 trials Expert Opin Emerg Drugs. 2024 Apr 28; 1-17. . View in PubMed
  • Atopic dermatitis (eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force on Practice Parameters GRADE- and Institute of Medicine-based recommendations Ann Allergy Asthma Immunol. 2024 Mar; 132(3):274-312. . View in PubMed
  • Constant vigilance! Managing threats to the skin barrier Ann Allergy Asthma Immunol. 2024 Feb 13. . View in PubMed
  • Solving the health disparity of eczema assessment: A role for skin tape soluble protein? J Allergy Clin Immunol Glob. 2024 Feb; 3(1):100180.. View in PubMed
  • Comparison of Old and New Systemic Treatments for Moderate to Severe Atopic Dermatitis Curr Allergy Asthma Rep. 2024 05; 24(5):289-301. . View in PubMed
  • Patients’ and Caregivers’ Preferences for Mental Health Care and Support in Atopic Dermatitis Dermatitis. 2024 Jan-Feb; 35(S1):S70-S76. . View in PubMed
  • Academic interest of allergists in atopic dermatitis before and after approval of systemic immunomodulators Ann Allergy Asthma Immunol. 2023 Dec; 131(6):779-781. . View in PubMed
  • History of Saureus Skin Infection Significantly Associates with History of Eczema Herpeticum in Patients with Atopic Dermatitis. Dermatol Ther (Heidelb). 2023 Oct; 13(10):2417-2429. . View in PubMed
  • Elevated serum total IgE is associated with eczema exacerbation in children hospitalized for atopic dermatitis Pediatr Dermatol. 2023 Mar; 40(2):301-304. . View in PubMed
  • Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials J Allergy Clin Immunol. 2023 12; 152(6):1470-1492. . View in PubMed
  • Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials J Allergy Clin Immunol. 2023 12; 152(6):1493-1519. . View in PubMed
  • Rapid reduction in Staphylococcus aureus in atopic dermatitis subjects following dupilumab treatment J Allergy Clin Immunol. 2023 11; 152(5):1179-1195. . View in PubMed
  • Phenotypic and Endotypic Determinants of Atopic Dermatitis Severity From the Atopic Dermatitis Research Network (ADRN) Registry J Allergy Clin Immunol Pract. 2023 08; 11(8):2504-2515. . View in PubMed
  • Atopic Dermatitis Yardstick update Ann Allergy Asthma Immunol. 2023 06; 130(6):811-820. . View in PubMed
  • The chicken or the egg of lymphopenia in atopic eczema J Eur Acad Dermatol Venereol. 2023 06; 37(6):1097-1098. . View in PubMed
  • Skin Antiseptics for Atopic Dermatitis: Dissecting Facts From Fiction J Allergy Clin Immunol Pract. 2023 05; 11(5):1385-1390. . View in PubMed
  • Safety, pharmacokinetics, and efficacy of ruxolitinib cream in children and adolescents with atopic dermatitisAnn Allergy Asthma Immunol. 2023 04; 130(4):500-507. e3. . View in PubMed
  • Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms J Allergy Clin Immunol. 2023 01; 151(1):147-158. . View in PubMed
  • Values and Preferences of Patients and Caregivers Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review JAMA Dermatol. 2023 03 01; 159(3):320-330. . View in PubMed
  • Recent advances in immunomodulators for atopic dermatitis Curr Opin Pediatr. 2023 12 01; 35(6):671-679. . View in PubMed
  • Food allergy testing in atopic dermatitis JAAD Int. 2022 Dec; 9:50-56. . View in PubMed
  • The Genetics of Eczema Herpeticum Clin Rev Allergy Immunol. 2022 Dec; 63(3):390-397. . View in PubMed
  • Epidemiology and Burden of Sleep Disturbances in Atopic Dermatitis in US Adults Dermatitis. 2022 Nov-Dec 01; 33(6S):S104-S113. . View in PubMed
  • Dietary Elimination for the Treatment of Atopic Dermatitis: A Systematic Review and Meta-AnalysisJ Allergy Clin Immunol Pract. 2022 10; 10(10):2657-2666. e8. . View in PubMed
  • Successful use of dupilumab to treat eczema in a child with X-linked agammaglobulinemia Ann Allergy Asthma Immunol. 2022 09; 129(3):384-386. . View in PubMed
  • Dupilumab nonresponders in atopic dermatitis Ann Allergy Asthma Immunol. 2022 09; 129(3):267-268. . View in PubMed
  • Aeroallergens in Atopic Dermatitis and Chronic Urticaria Curr Allergy Asthma Rep. 2022 07; 22(7):67-75. . View in PubMed
  • Bleach baths for atopic dermatitis: A systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADEAnn Allergy Asthma Immunol. 2022 06; 128(6):660-668. e9. . View in PubMed
  • EAACI Biologicals Guidelines-Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12-17 years old Allergy. 2022 01; 77(1):17-38. . View in PubMed
  • Complete blood count profiles in children with eczema herpeticum Pediatr Allergy Immunol. 2022 01; 33(1):e13648. . View in PubMed
  • Polygenic prediction of atopic dermatitis improves with atopic training and filaggrin factors J Allergy Clin Immunol. 2022 01; 149(1):145-155. . View in PubMed
  • Genetic/Environmental Contributions and Immune Dysregulation in Children with Atopic Dermatitis J Asthma Allergy. 2022; 15:1681-1700. . View in PubMed
  • Atopic dermatitis: Is innate or adaptive immunity in control? A clinical perspective. Front Immunol. 2022; 13:943640.. View in PubMed
  • Multiethnic genome-wide and HLA association study of total serum IgE level J Allergy Clin Immunol. 2021 12; 148(6):1589-1595. . View in PubMed
  • Whole genome sequencing identifies novel genetic mutations in patients with eczema herpeticum Allergy. 2021 08; 76(8):2510-2523. . View in PubMed
  • EAACI Biologicals Guidelines-dupilumab for children and adults with moderate-to-severe atopic dermatitis Allergy. 2021 04; 76(4):988-1009. . View in PubMed
  • Discrepancy in antibiotic prescription for atopic dermatitis exacerbation between ethnic groups J Allergy Clin Immunol Pract. 2021 04; 9(4):1717-1718. . View in PubMed
  • Efficacy and safety of dupilumab for moderate-to-severe atopic dermatitis: A systematic review for the EAACI biologicals guidelines Allergy. 2021 01; 76(1):45-58. . View in PubMed
  • The infectious complications of atopic dermatitis Ann Allergy Asthma Immunol. 2021 01; 126(1):3-12. . View in PubMed
  • Efficacy and safety of treatment with omalizumab for chronic spontaneous urticaria: A systematic review for the EAACI Biologicals Guidelines Allergy. 2021 01; 76(1):59-70. . View in PubMed
  • Validation of five patient-reported outcomes for atopic dermatitis severity in adults Br J Dermatol. 2020 01; 182(1):104-111. . View in PubMed
  • Are avoidance diets still warranted in children with atopic dermatitis? Pediatr Allergy Immunol. 2020 01; 31(1):19-26.. View in PubMed
  • Update on Atopic Dermatitis: Diagnosis, Severity Assessment, and Treatment Selection J Allergy Clin Immunol Pract. 2020 01; 8(1):91-101. . View in PubMed
  • Pain Is a Common and Burdensome Symptom of Atopic Dermatitis in United States AdultsJ Allergy Clin Immunol Pract. 2019 Nov – Dec; 7(8):2699-2706. e7. . View in PubMed
  • Distribution of atopic dermatitis lesions in United States adults J Eur Acad Dermatol Venereol. 2019 Jul; 33(7):1341-1348. . View in PubMed
  • Atopic Dermatitis in US Adults: From Population to Health Care UtilizationJ Allergy Clin Immunol Pract. 2019 May – Jun; 7(5):1524-1532. e2. . View in PubMed
  • Validation and Interpretation of Short Form 12 and Comparison with Dermatology Life Quality Index in Atopic Dermatitis in AdultsJ Invest Dermatol. 2019 10; 139(10):2090-2097. e3. . View in PubMed
  • Symptoms and diagnosis of anxiety and depression in atopic dermatitis in US. adults. Br J Dermatol. 2019 09; 181(3):554-565. . View in PubMed
  • Measurement Properties of the Hospital Anxiety and Depression Scale Used in Atopic Dermatitis in Adults J Invest Dermatol. 2019 06; 139(6):1388-1391. . View in PubMed
  • Health Utility Scores of Atopic Dermatitis in US AdultsJ Allergy Clin Immunol Pract. 2019 04; 7(4):1246-1252. e1. . View in PubMed
  • Atopic Dermatitis in America Study: A Cross-Sectional Study Examining the Prevalence and Disease Burden of Atopic Dermatitis in the US Adult Population J Invest Dermatol. 2019 03; 139(3):583-590. . View in PubMed
  • Antibiotic choice and methicillin-resistant Staphylococcus aureus rate in children hospitalized for atopic dermatitis Ann Allergy Asthma Immunol. 2019 03; 122(3):314-317. . View in PubMed
  • The PATHOGENesis of Food Allergy Front Pediatr. 2019; 7:484. . View in PubMed
  • Content and construct validity, predictors, and distribution of self-reported atopic dermatitis severity in US adultsAnn Allergy Asthma Immunol. 2018 12; 121(6):729-734. e4. . View in PubMed
  • History of eczema is associated with more severe hospital course in children hospitalized for asthma Ann Allergy Asthma Immunol. 2018 12; 121(6):735-736. . View in PubMed
  • Association of atopic dermatitis with allergic, autoimmune, and cardiovascular comorbidities in US adultsAnn Allergy Asthma Immunol. 2018 11; 121(5):604-612. e3. . View in PubMed
  • Severity strata for POEM, PO-SCORAD, and DLQI in US adults with atopic dermatitisAnn Allergy Asthma Immunol. 2018 10; 121(4):464-468. e3. . View in PubMed
  • Patient burden and quality of life in atopic dermatitis in US adults: A population-based cross-sectional study Ann Allergy Asthma Immunol. 2018 09; 121(3):340-347. . View in PubMed
  • Immediate Superficial Venous Thrombophlebitis Associated with Intravenous Administration of Ciprofloxacin J Pediatr. 2018 09; 200:289. . View in PubMed
  • Atopic dermatitis yardstick: Practical recommendations for an evolving therapeutic landscapeAnn Allergy Asthma Immunol. 2018 01; 120(1):10-22. e2. . View in PubMed
  • Moving toward a more precise treatment of atopic dermatitis Ann Allergy Asthma Immunol. 2018 01; 120(1):3-4. . View in PubMed
  • Severe Atopic Dermatitis in Children Curr Allergy Asthma Rep. 2018 05 10; 18(6):35. . View in PubMed
  • Atopic dermatitis: pathogenesis Semin Cutan Med Surg. 2017 Sep; 36(3):100-103. . View in PubMed
  • Infectious Complications in Atopic Dermatitis Immunol Allergy Clin North Am. 2017 02; 37(1):75-93. . View in PubMed
  • Allergic Skin Diseases Immunol Allergy Clin North Am. 2017 02; 37(1):xv-xvi. . View in PubMed
  • Bacterial and Viral Infections in Atopic Dermatitis: a Comprehensive Review Clin Rev Allergy Immunol. 2016 Dec; 51(3):329-337. . View in PubMed
  • Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcusaureus and Encoded Virulence Factors mSphere. 2016 Nov-Dec; 1(6). . View in PubMed
  • Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology J Allergy Clin Immunol. 2016 05; 137(5):1347-58. . View in PubMed
  • Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases J Allergy Clin Immunol. 2015 Nov; 136(5):1337-45. . View in PubMed
  • The Role of Skin Barrier in the Pathogenesis of Food Allergy Children (Basel). 2015 Sep 02; 2(3):382-402. . View in PubMed
  • Synbiotics-supplemented amino acid-based formula supports adequate growth in cow’s milk allergic infants Pediatr Allergy Immunol. 2015 Jun; 26(4):316-22. . View in PubMed
  • Major histocompatibility complex class II deficiency complicated by Mycobacterium avium complex in a boy of mixed ethnicity J Clin Immunol. 2014 Aug; 34(6):677-80. . View in PubMed
  • Recurrent MRSA skin infections in atopic dermatitis J Allergy Clin Immunol Pract. 2014 Jul-Aug; 2(4):396-9. . View in PubMed
  • Association between egg and staphylococcal superantigen IgE sensitizations in atopic dermatitis Allergy Asthma Proc. 2014 Jul-Aug; 35(4):346-8. . View in PubMed
  • Emergence of multiresistant methicillin-resistant Staphylococcus aureus in two patients with atopic dermatitis requiring linezolid treatment Pediatr Dermatol. 2014 Mar-Apr; 31(2):245-8. . View in PubMed
  • New insights in the pathogenesis of atopic dermatitis Pediatr Res. 2014 Jan; 75(1-2):171-5. . View in PubMed
  • Hepatic veno-occlusive disease with immunodeficiency (VODI): first reported case in the US. and identification of a unique mutation in Sp110. Clin Immunol. 2012 Nov; 145(2):102-7. . View in PubMed
  • Clinical, molecular, and cellular immunologic findings in patients with SP110-associated veno-occlusive disease with immunodeficiency syndromeJ Allergy Clin Immunol. 2012 Sep; 130(3):735-742. e6. . View in PubMed
  • Editorial update on emerging treatments of atopic dermatitis Expert Opin Emerg Drugs. 2012 Jun; 17(2):129-33. . View in PubMed
  • Association of microbial IgE sensitizations with asthma in young children with atopic dermatitis Ann Allergy Asthma Immunol. 2012 Mar; 108(3):212-3. . View in PubMed
  • A case of atopic dermatitis and erythema multiforme Eur Ann Allergy Clin Immunol. 2012 Feb; 44(1):30-1. . View in PubMed
  • Hypohidrotic ectodermal dysplasia and immunodeficiency with coincident NEMO and EDA mutations Front Immunol. 2011; 2:61. . View in PubMed
  • Participation in continuing professional development by dental practitioners in Victoria, Australia in 2007 Eur J Dent Educ. 2010 Nov; 14(4):227-34. . View in PubMed
  • Human beta defensin-2: too good to be dismissed in atopic dermatitis J Invest Dermatol. 2010 Aug; 130(8):2138-9. . View in PubMed
  • Investigational and unproven therapies in atopic dermatitis Immunol Allergy Clin North Am. 2010 Aug; 30(3):425-39. . View in PubMed
  • The infectious aspects of atopic dermatitis Immunol Allergy Clin North Am. 2010 Aug; 30(3):309-21. . View in PubMed
  • Late-onset of IgE sensitization to microbial allergens in young children with atopic dermatitis Br J Dermatol. 2010 Jan; 162(1):159-61. . View in PubMed
  • Skin-deep clues to a complex disease Ann Allergy Asthma Immunol. 2010 Jan; 104(1):93-4. . View in PubMed
  • Emerging drugs for atopic dermatitis Expert Opin Emerg Drugs. 2009 Mar; 14(1):165-79. . View in PubMed
  • Association of staphylococcal superantigen-specific immunoglobulin e with mild and moderate atopic dermatitis J Pediatr. 2008 Dec; 153(6):803-6. . View in PubMed
  • Atopic dermatitis Prim Care. 2008 Mar; 35(1):105-17vii. . View in PubMed
  • Down-regulation of atopic dermatitis-associated serum chemokines by wet-wrap treatment: a pilot study Ann Allergy Asthma Immunol. 2008 Mar; 100(3):286-7. . View in PubMed
  • 2008 Feb; 121(2):536-7; author reply 537. . View in PubMed
  • Pectin anaphylaxis and possible association with cashew allergy Ann Allergy Asthma Immunol. 2006 Dec; 97(6):759-60. . View in PubMed
  • Immune dysregulation in atopic dermatitis Curr Allergy Asthma Rep. 2006 Sep; 6(5):384-9. . View in PubMed
  • Is/are pattern recognition receptor(s) for Staphylococcus aureus defective in atopic dermatitis? Dermatology. 2006; 212(1):19-22.. View in PubMed
  • Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes J Immunol. 2003 Sep 15; 171(6):3262-9. . View in PubMed
  • Unresponsive wheezing to asthma therapy in a 32-year-old female Ann Allergy Asthma Immunol. 2003 Feb; 90(2):199-202. . View in PubMed
  • The chemokine receptor CCR6 identifies interferon-gamma expressing T cells and is decreased in atopic dermatitis as compared with psoriasis J Invest Dermatol. 2002 Dec; 119(6):1463-4. . View in PubMed
  • Endogenous antimicrobial peptides and skin infections in atopic dermatitis N Engl J Med. 2002 Oct 10; 347(15):1151-60. . View in PubMed
  • Atopic dermatitis Clin Allergy Immunol. 2002; 16:355-79. . View in PubMed
  • Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis J Immunol. 2002 Jan 01; 168(1):505-10. . View in PubMed
  • Cross-sectional study of near-work and myopia in kindergarten children in Singapore Ann Acad Med Singap. 2000 Nov; 29(6):740-4. . View in PubMed
  • Are atopic individuals genetically predisposed to produce a specific protease profile in antigen processing? Med Hypotheses. 1999 Jul; 53(1):19-21.. View in PubMed