Prasad C. Tongaonkar, PhD

Assistant Professor of Research Pathology

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Publications

  • Inhibition of miR-146a Expression and Regulation of Endotoxin Tolerance by Rhesus Theta-Defensin-1 Mediators Inflamm. 2023; 2023:8387330. . View in PubMed
  • RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts Physiol Genomics. 2019 12 01; 51(12):657-667. . View in PubMed
  • Antimicrob Agents Chemother. 2018 06; 62(6). . View in PubMed
  • J Biol Chem. 2018 02 23; 293(8):2725-2734. . View in PubMed
  • PLoS One. 2017; 12(11):e0187868. . View in PubMed
  • Rhesus macaque? B and MAPK pathways. J Leukoc Biol. 2015 Dec; 98(6):1061-70.. View in PubMed
  • Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis PLoS One. 2012; 7(12):e51337. . View in PubMed
  • High fidelity processing and activation of the human a-defensin HNP1 precursor by neutrophil elastase and proteinase 3 PLoS One. 2012; 7(3):e32469. . View in PubMed
  • J Leukoc Biol. 2011 Feb; 89(2):283-90. . View in PubMed
  • SDF2L1, a component of the endoplasmic reticulum chaperone complex, differentially interacts with {alpha}-, {beta}-, and {theta}-defensin propeptides J Biol Chem. 2009 Feb 27; 284(9):5602-9. . View in PubMed
  • Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30 Mol Cell Biol. 2008 Nov; 28(21):6709-19. . View in PubMed
  • Histones are required for transcription of yeast rRNA genes by RNA polymerase I Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10129-34. . View in PubMed
  • SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast Cell. 2004 May 14; 117(4):441-53. . View in PubMed
  • Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathway Nucleic Acids Res. 2004; 32(22):6490-500. . View in PubMed
  • Purification and assay of upstream activation factor, core factor, Rrn3p, and yeast RNA polymerase I Methods Enzymol. 2003; 370:109-20. . View in PubMed
  • Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation Mol Cell Biol. 2000 Aug; 20(16):6062-73. . View in PubMed
  • Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome Mol Cell Biol. 2000 Jul; 20(13):4691-8. . View in PubMed
  • Characterization of a temperature-sensitive mutant of a ubiquitin-conjugating enzyme and its use as a heat-inducible degradation signal Anal Biochem. 1999 Aug 01; 272(2):263-9. . View in PubMed
  • Reconstituting ubiquitination reactions with affinity-purified components and 32P-ubiquitin Anal Biochem. 1998 Jul 01; 260(2):135-41. . View in PubMed
  • Sequence elements that contribute to the degradation of yeast G alpha Genes Cells. 1998 May; 3(5):307-19. . View in PubMed
  • Rad23 links DNA repair to the ubiquitin/proteasome pathway Nature. 1998 Feb 12; 391(6668):715-8. . View in PubMed
  • A semi-empirical method for prediction of antigenic determinants on protein antigens FEBS Lett. 1990 Dec 10; 276(1-2):172-4. . View in PubMed