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Qiulan Ma

Research Associate Professor of Neurology (Part-Time)

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Email [email protected]
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Publications

  • Evidence for cPLA2 activation in Alzheimer’s disease synaptic pathology. Acta Neuropathol Commun. 2026 Feb 12; 14(1).. View in PubMed
  • Development of potent, selective cPLA2 inhibitors for targeting neuroinflammation in Alzheimer’s disease and other neurodegenerative disorders. NPJ Drug Discov. 2026; 3(1):2.. View in PubMed
  • An association of CSF apolipoprotein E glycosylation and amyloid-beta 42 in individuals who carry the APOE4 allele. Alzheimers Res Ther. 2023 05 23; 15(1):96.. View in PubMed
  • The Novel Omega-6 Fatty Acid Docosapentaenoic Acid Positively Modulates Brain Innate Immune Response for Resolving Neuroinflammation at Early and Late Stages of Humanized APOE-Based Alzheimer’s Disease Models. Front Immunol. 2020; 11:558036.. View in PubMed
  • Curcumin-loaded PLGA-PEG nanoparticles conjugated with B6 peptide for potential use in Alzheimer’s disease. Drug Deliv. 2018 Nov; 25(1):1091-1102.. View in PubMed
  • Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer’s disease. Neurobiol Dis. 2018 06; 114:120-128.. View in PubMed
  • Clinical development of curcumin in neurodegenerative disease. Expert Rev Neurother. 2015 Jun; 15(6):629-37.. View in PubMed
  • Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging. J Neurosci. 2014 May 21; 34(21):7124-36.. View in PubMed
  • Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice. J Biol Chem. 2013 Feb 08; 288(6):4056-65.. View in PubMed
  • PAK in Alzheimer disease, Huntington disease and X-linked mental retardation. Cell Logist. 2012 Apr 01; 2(2):117-125.. View in PubMed
  • C-terminal part of α-synuclein mediates its activity in promoting proliferation of dopaminergic cells. J Neural Transm (Vienna). 2011 Aug; 118(8):1155-64.. View in PubMed
  • Dietary fatty acids and the aging brain. Nutr Rev. 2010 Dec; 68 Suppl 2:S102-11.. View in PubMed
  • Omega-3 fatty acids and dementia. Prostaglandins Leukot Essent Fatty Acids. 2009 Aug-Sep; 81(2-3):213-21.. View in PubMed
  • Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin. J Neurosci. 2009 Jul 15; 29(28):9078-89.. View in PubMed
  • Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid. Arch Neurol. 2009 Apr; 66(4):448-57.. View in PubMed
  • GSK3 inhibitors show benefits in an Alzheimer’s disease (AD) model of neurodegeneration but adverse effects in control animals. Neurobiol Dis. 2009 Feb; 33(2):193-206.. View in PubMed
  • p21-activated kinase-aberrant activation and translocation in Alzheimer disease pathogenesis. J Biol Chem. 2008 May 16; 283(20):14132-43.. View in PubMed
  • Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer’s disease (AD): relevance to AD prevention. J Neurosci. 2007 Dec 26; 27(52):14299-307.. View in PubMed
  • Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer’s models. J Neurochem. 2007 Nov; 103(4):1594-607.. View in PubMed
  • Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro. J Neurosci Res. 2006 Feb 15; 83(3):374-84.. View in PubMed
  • Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. Nat Neurosci. 2006 Feb; 9(2):234-42.. View in PubMed
  • Prevention of Alzheimer’s disease: Omega-3 fatty acid and phenolic anti-oxidant interventions. Neurobiol Aging. 2005 Dec; 26 Suppl 1:133-6.. View in PubMed
  • Association between acyl-coenzyme A: cholesterol acyltransferase gene and risk for Alzheimer’s disease in Chinese. Neurosci Lett. 2005 Nov 04; 388(1):17-20.. View in PubMed
  • Demonstration of a role for alpha-synuclein as a functional microtubule-associated protein. J Alzheimers Dis. 2004 Aug; 6(4):435-42; discussion 443-9.. View in PubMed
  • [New polymorphism (IVS3-20 T–>C) of the parkin gene associated with the early-onset Parkinson’s disease in Chinese]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Jun; 21(3):219-23.. View in PubMed
  • [Association between NAD(P)H: quinone oxidoreductase and apolipoprotein E gene polymorphisms in Alzheimer’s disease]. Zhonghua Yi Xue Za Zhi. 2003 Dec 25; 83(24):2124-7.. View in PubMed
  • Alpha-synuclein aggregation and neurodegenerative diseases. J Alzheimers Dis. 2003 Apr; 5(2):139-48.. View in PubMed
  • [Association between DLST gene polymorphism and Alzheimer’s disease]. Zhonghua Yi Xue Za Zhi. 2001 Oct 25; 81(20):1246-8.. View in PubMed
  • [Analysis of the interaction of the polymorphisms of presenilin-1 gene and ApoE gene in Alzheimerns disease]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2000 Dec; 17(6):390-4.. View in PubMed
  • [A study on mutation of exon 5 of presenilin-1 in Alzheimer’s disease]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1999 Dec; 16(6):349-52.. View in PubMed

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