Radu O. Minea, MD

Assistant Professor of Research Neurological Surgery

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Publications

Potent Therapeutic Activity of NEO212 in Preclinical Models of Human and Canine Leukaemia and Lymphoma. Vet Comp Oncol. 2025 Sep; 23(3):412-423.. View in PubMed
NEO212, temozolomide conjugated to NEO100, exerts superior therapeutic activity over temozolomide in preclinical chemoradiation models of glioblastoma. Neurooncol Adv. 2024 Jan-Dec; 6(1):vdae095.. View in PubMed
Activation of Epstein-Barr Virus’ Lytic Cycle in Nasopharyngeal Carcinoma Cells by NEO212, a Conjugate of Perillyl Alcohol and Temozolomide. Cancers (Basel). 2024 Feb 26; 16(5).. View in PubMed
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate. Autophagy. 2023 12; 19(12):3169-3188.. View in PubMed
Enhanced brain entry of checkpoint-inhibitory therapeutic antibodies facilitated by intraarterial NEO100 in mouse models of brain-localized malignancies. J Neurosurg. 2023 09 01; 139(3):822-830.. View in PubMed
NEO212, a Perillyl Alcohol-Temozolomide Conjugate, Triggers Macrophage Differentiation of Acute Myeloid Leukemia Cells and Blocks Their Tumorigenicity. Cancers (Basel). 2022 Dec 09; 14(24).. View in PubMed
Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia. Cancers (Basel). 2021 Jul 06; 13(14).. View in PubMed
Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas. PLoS One. 2020; 15(9):e0238238.. View in PubMed
Cytotoxic impact of a perillyl alcohol-temozolomide conjugate, NEO212, on cutaneous T-cell lymphoma in vitro. Ther Adv Med Oncol. 2019; 11:1758835919891567.. View in PubMed
A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice. Molecules. 2018 Nov 08; 23(11).. View in PubMed

Radu O. Minea, MD

Publications

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