Rema Raman, PhD

Professor of Neurology

Director, Biostatistics Core

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Overview

Rema Raman is a Professor of Neurology at Keck School of Medicine of USC and the Director of the Biostatistics Section and the Recruitment, Engagement, and Retention (RER) Section at the USC Alzheimer’s Therapeutic Research Institute (ATRI). Dr. Raman serves as co-lead of several key units within the NIH-funded Alzheimer’s Clinical Trials Consortium, including Biostatistics, Recruitment, Engagement & Retention (RER), and Alzheimer’s Clinical Trials – Education, Engagement, Access, and Accountability (ACT-E2A2).
Dr. Raman has focused her academic career in the design, conduct and analysis of clinical trials in neurology. She has extensive experience as a collaborative biostatistician and clinical trialist, serving in the leadership team of several highly integrated and interdisciplinary research programs conducting clinical research in Alzheimer¹s disease, stroke, post-traumatic stress disorder, and traumatic brain injury. Her primary statistical research interests are in innovative trial design, advanced statistical methods for missing and correlated data, centralized statistical monitoring, and strategies to improve participant recruitment and retention.
Dr. Raman is committed to the effective teaching of biostatistics and clinical trial methodology to undergraduate, graduate, and medical students, postdoctoral fellows and other clinical researchers. She is co-director of the NIA- and Alzheimer’s Association- funded Institute of Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD) program that aims to educate and train the next generation of clinical trial researchers and future principal investigators in the field of Alzheimer’s Disease and Related Disorders clinical trials research.

Education and Training

  • University of Illinois at Chicago, Chicago, IL — Ph.D. — Biostatistics
  • University of Iowa, Iowa City, IA — M.S. — Biostatistics
  • Bowling Green State University, Bowling Green, OH — M.A — Scientific Computation (Applied Mathematics)

Research Keywords

  • Clinical Biostatistics
  • Clinical Trials
  • Neurology
  • Alzheimer's Disease
  • Recruitment and Retention science

Publications

  • Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial. Lancet. 2026 Aug 01; 408(10553):417-429.. View in PubMed
  • Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world. Alzheimers Dement. 2026 Jul; 22(7):e71696.. View in PubMed
  • Improving the clinical trial landscape for patients with atypical variants of Alzheimer’s disease: a call to action. Alzheimers Dement. 2026 Jun; 22(6):e71521.. View in PubMed
  • A scoping review of dementia education programs for Chinese, Japanese, Korean, Filipino, and Vietnamese communities. Alzheimers Dement (Amst). 2026 Apr-Jun; 18(2):e70295.. View in PubMed
  • Late-life body mass index and amyloid interaction on cognitive decline in unimpaired older adults. J Prev Alzheimers Dis. 2026 May; 13(5):100543.. View in PubMed
  • Divergent patterns of cognitive decline in preclinical Alzheimer’s disease: Implications for secondary prevention trials. Alzheimers Dement. 2026 Apr; 22(4):e71366.. View in PubMed
  • Evaluating evidence-based recruitment strategies for Alzheimer’s disease and related dementias clinical trial research: A literature review. J Prev Alzheimers Dis. 2026 May; 13(5):100532.. View in PubMed
  • Amyloid Imaging and APOE Genotype Disclosure and Short-Term Psychological Distress. JAMA Netw Open. 2026 03 02; 9(3):e263845.. View in PubMed
  • Uniform Amyloid Thresholds Across Populations. JAMA Neurol. 2026 Mar 01; 83(3):296-299.. View in PubMed
  • The relationships between ethnoracial identity, Aβ positivity, APOEε4, and medial temporal lobe tau PET. Alzheimers Dement. 2026 Mar; 22(3):e71226.. View in PubMed