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Rema Raman, PhD

Professor of Neurology

Director, Biostatistics Core

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Phone +1 858 964 0673
Email remar@usc.edu
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Overview

Rema Raman is a Professor of Neurology at Keck School of Medicine of USC and the Director of the Biostatistics Section and the Recruitment, Engagement, and Retention (RER) Section at the USC Alzheimer’s Therapeutic Research Institute (ATRI). Dr. Raman serves as co-lead of several key units within the NIH-funded Alzheimer’s Clinical Trials Consortium, including Biostatistics, Recruitment, Engagement & Retention (RER), and Alzheimer’s Clinical Trials – Education, Engagement, Access, and Accountability (ACT-E2A2).
Dr. Raman has focused her academic career in the design, conduct and analysis of clinical trials in neurology. She has extensive experience as a collaborative biostatistician and clinical trialist, serving in the leadership team of several highly integrated and interdisciplinary research programs conducting clinical research in Alzheimer¹s disease, stroke, post-traumatic stress disorder, and traumatic brain injury. Her primary statistical research interests are in innovative trial design, advanced statistical methods for missing and correlated data, centralized statistical monitoring, and strategies to improve participant recruitment and retention.
Dr. Raman is committed to the effective teaching of biostatistics and clinical trial methodology to undergraduate, graduate, and medical students, postdoctoral fellows and other clinical researchers. She is co-director of the NIA- and Alzheimer’s Association- funded Institute of Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD) program that aims to educate and train the next generation of clinical trial researchers and future principal investigators in the field of Alzheimer’s Disease and Related Disorders clinical trials research.

Publications

  • Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer’s disease: a neuropsychological data-driven approach Alzheimers Res Ther. 2025 Feb 06; 17(1):38. . View in PubMed
  • Disclosure of elevated amyloid status is not associated with long-term suicidality in a preclinical AD trial Alzheimers Dement. 2025 Feb; 21(2):e14623. . View in PubMed
  • Clinical criteria for limbic-predominant age-related TDP-43 encephalopathy Alzheimers Dement. 2025 Jan; 21(1):e14202. . View in PubMed
  • Artificial intelligence-enabled safety monitoring in Alzheimer’s disease clinical trials J Prev Alzheimers Dis. 2025 Jan; 12(1):100002. . View in PubMed
  • Achieving Inclusion in Pharmacological Clinical Trials for Alzheimer’s Disease Curr Top Behav Neurosci. 2025; 69:229-242. . View in PubMed
  • Cortico-limbic volume abnormalities in late life depression are distinct from ß amyloid and white matter pathologies Mol Psychiatry. 2024 Nov 07. . View in PubMed
  • Anxiety in late-life depression is associated with poorer performance across multiple cognitive domains J Int Neuropsychol Soc. 2024 Nov; 30(9):807-811. . View in PubMed
  • Anxiety in late-life depression: Associations with brain volume, amyloid beta, white matter lesions, cognition, and functional ability Int Psychogeriatr. 2024 11; 36(11):1009-1020. . View in PubMed
  • Anxiety in late-life depression: Associations with brain volume, amyloid beta, white matter lesions, cognition, and functional ability Int Psychogeriatr. 2024 Nov; 36(11):1009-1020. . View in PubMed
  • The Alzheimer’s Disease Neuroimaging Initiative Clinical Core Alzheimers Dement. 2024 Oct; 20(10):7361-7368. . View in PubMed
  • A Protocol for the Inclusion of Minoritized Persons in Alzheimer Disease Research From the ADNI3 Diversity Taskforce JAMA Netw Open. 2024 08 01; 7(8):e2427073. . View in PubMed
  • Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer’s disease trial Alzheimers Dement. 2024 06; 20(6):3827-3838. . View in PubMed
  • The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact Alzheimers Dement. 2024 06; 20(6):4290-4314. . View in PubMed
  • The AUstralian multidomain Approach to Reduce dementia Risk by prOtecting brain health With lifestyle intervention study (AU-ARROW): A study protocol for a single-blind, multi-site, randomized controlled trial Alzheimers Dement (N Y). 2024 Apr-Jun; 10(2):e12466. . View in PubMed
  • Immediate Reactions to Alzheimer Biomarker Disclosure in Cognitively Unimpaired Individuals in a Global Truncated Randomized Trial Neurol Clin Pract. 2024 Apr; 14(2):e200265. . View in PubMed
  • Relationship of Hoarding and Depression Symptoms in Older Adults Am J Geriatr Psychiatry. 2024 04; 32(4):497-508. . View in PubMed
  • Study design and methods: US. study to protect brain health through lifestyle intervention to reduce risk (U. S. POINTER). Alzheimers Dement. 2024 02; 20(2):769-782. . View in PubMed
  • Eligibility Rates among Racially and Ethnically Diverse US Participants in Phase 2 and Phase 3 Placebo-Controlled, Double-Blind, Randomized Trials of Lecanemab and Elenbecestat in Early Alzheimer Disease Ann Neurol. 2024 Feb; 95(2):288-298. . View in PubMed
  • Plasma Aß42/Aß40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer’s disease Alzheimers Dement. 2024 02; 20(2):1214-1224. . View in PubMed
  • Pre-Randomization Predictors of Study Discontinuation in a Preclinical Alzheimer’s Disease Randomized Controlled Trial J Prev Alzheimers Dis. 2024; 11(4):874-880. . View in PubMed
  • Ascertainment and Statistical Issues for Randomized Trials of Cardiovascular Interventions for Cognitive Impairment and Dementia Hypertension. 2024 Jan; 81(1):45-53. . View in PubMed
  • Trial of Solanezumab in Preclinical Alzheimer’s Disease N Engl J Med. 2023 Sep 21; 389(12):1096-1107. . View in PubMed
  • Evaluation of Neighborhood-Level Disadvantage and Cognition in Mexican American and Non-Hispanic White Adults 50 Years and Older in the US JAMA Netw Open. 2023 08 01; 6(8):e2325325. . View in PubMed
  • Centralizing prescreening data collection to inform data-driven approaches to clinical trial recruitment Alzheimers Res Ther. 2023 05 02; 15(1):88. . View in PubMed
  • Natural cubic splines for the analysis of Alzheimer’s clinical trials Pharm Stat. 2023 May-Jun; 22(3):508-519. . View in PubMed
  • The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer’s disease Alzheimers Dement. 2023 04; 19(4):1227-1233. . View in PubMed
  • Improving generalizability and study design of Alzheimer’s disease cohort studies in the United States by including under-represented populations Alzheimers Dement. 2023 04; 19(4):1549-1557. . View in PubMed
  • Safety and tolerability of lumbar puncture for the evaluation of Alzheimer’s disease Alzheimers Dement (Amst). 2023 Apr-Jun; 15(2):e12431. . View in PubMed
  • The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs Alzheimers Dement. 2023 Mar 11. . View in PubMed
  • Protective effects of sleep duration and physical activity on cognitive performance are influenced by ß-amyloid and brain volume but not tau burden among cognitively unimpaired older adults Neuroimage Clin. 2023; 39:103460. . View in PubMed
  • Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer’s Disease J Alzheimers Dis. 2023; 92(1):95-107. . View in PubMed
  • Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) Alzheimers Dement. 2022 12; 18(12):2603-2613. . View in PubMed
  • Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer’s disease Alzheimers Res Ther. 2022 11 15; 14(1):173. . View in PubMed
  • What Should the Goals Be for Diverse Recruitment in Alzheimer Clinical Trials? JAMA Neurol. 2022 11 01; 79(11):1097-1098.. View in PubMed
  • Alzheimer’s disease research progress in the Mediterranean region: The Alzheimer’s Association International Conference Satellite Symposium Alzheimers Dement. 2022 10; 18(10):1957-1968. . View in PubMed
  • Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer’s Symposium Alzheimers Dement. 2022 09; 18(9):1677-1686. . View in PubMed
  • Early-stage Alzheimer disease: getting trial-ready Nat Rev Neurol. 2022 07; 18(7):389-399. . View in PubMed
  • Intranasal insulin modulates cerebrospinal fluid markers of neuroinflammation in mild cognitive impairment and Alzheimer’s disease: a randomized trial Sci Rep. 2022 01 25; 12(1):1346. . View in PubMed
  • Tackling a Major Deficiency of Diversity in Alzheimer’s Disease Therapeutic Trials: An CTAD Task Force Report J Prev Alzheimers Dis. 2022; 9(3):388-392. . View in PubMed
  • Enhanced Association of Tau Pathology and Cognitive Impairment in Mild Cognitive Impairment Subjects with Behavior Symptoms J Alzheimers Dis. 2022; 87(2):557-568. . View in PubMed
  • Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial JAMA Netw Open. 2021 07 01; 4(7):e2114364. . View in PubMed
  • Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer’s Disease Neuroimaging Initiative Depression Project Biol Psychiatry. 2021 04 15; 89(8):757-765. . View in PubMed
  • Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial JAMA Neurol. 2021 03 01; 78(3):293-301. . View in PubMed
  • The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression J Alzheimers Dis. 2021; 80(3):991-1002. . View in PubMed
  • The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD): A Novel Clinical Trials Training Program J Prev Alzheimers Dis. 2021; 8(3):286-291. . View in PubMed
  • Brain amyloid burden, sleep, and 24-hour rest/activity rhythms: screening findings from the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration Studies Sleep Adv. 2021; 2(1):zpab015. . View in PubMed
  • Impact of the COVID-19 pandemic on statistical design and analysis plans for multidomain intervention clinical trials: Experience from World-Wide FINGERS Alzheimers Dement (N Y). 2021; 7(1):e12143. . View in PubMed
  • Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study Alzheimers Dement (N Y). 2021; 7(1):e12135. . View in PubMed
  • Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment JAMA Neurol. 2020 12 01; 77(12):1504-1513. . View in PubMed
  • Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial JAMA Neurol. 2020 09 01; 77(9):1099-1109. . View in PubMed
  • Tobacco use and E-cigarette regulation: Perspectives of University Students in the Asia-Pacific Addict Behav. 2020 08; 107:106420. . View in PubMed
  • World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia Alzheimers Dement. 2020 07; 16(7):1078-1094. . View in PubMed
  • Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals JAMA Neurol. 2020 06 01; 77(6):735-745. . View in PubMed
  • Levetiracetam Versus Phenobarbital for Neonatal Seizures: A Randomized Controlled Trial Pediatrics. 2020 06; 145(6). . View in PubMed
  • TRC-PAD: Accelerating Recruitment of AD Clinical Trials through Innovative Information Technology J Prev Alzheimers Dis. 2020; 7(4):226-233. . View in PubMed
  • Viewpoint: Futility Analyses in Alzheimer’s Disease (AD) Clinical Trials: A Risky Business J Prev Alzheimers Dis. 2020; 7(3):195-196. . View in PubMed
  • The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer’s Disease (TRC-PAD) Project: An Overview J Prev Alzheimers Dis. 2020; 7(4):208-212. . View in PubMed
  • Statistical methods in handling placebo effect Int Rev Neurobiol. 2020; 153:103-120. . View in PubMed
  • Authors response to D Umbricht, letter to the editor referring Futility Analyses in Alzheimer’s Disease (AD) Clinical Trials: A Risky BusinessThe Journal of Prevention of Alzheimer’s Disease, 2020. J Prev Alzheimers Dis. 2020; 7(4):300. . View in PubMed
  • Predicting Amyloid Burden to Accelerate Recruitment of Secondary Prevention Clinical Trials J Prev Alzheimers Dis. 2020; 7(4):213-218. . View in PubMed
  • Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study Alzheimers Dement (Amst). 2020; 12(1):e12118. . View in PubMed
  • The Trial-Ready Cohort for Preclinical and Prodromal Alzheimer’s Disease (TRC-PAD): Experience from the First 3 Years J Prev Alzheimers Dis. 2020; 7(4):234-241. . View in PubMed
  • A mixed-methods study of cultural beliefs about dementia and genetic testing among Mexicans and Mexican-Americans at-risk for autosomal dominant Alzheimer’s disease J Genet Couns. 2019 10; 28(5):921-932. . View in PubMed
  • Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial JAMA Neurol. 2019 Oct 01; 76(10):1219-1229. . View in PubMed
  • Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer’s Disease N Engl J Med. 2019 04 11; 380(15):1483-1485. . View in PubMed
  • International chicken trade and increased risk for introducing or reintroducing highly pathogenic avian influenza A (H5N1) to uninfected countries Infect Dis Model. 2017 Nov; 2(4):412-418. . View in PubMed
  • Randomized controlled trial of acceptance and commitment therapy for distress and impairment in OEF/OIF/OND veterans Psychol Trauma. 2017 Aug; 9(Suppl 1):74-84. . View in PubMed
  • A randomized controlled trial of ganaxolone in posttraumatic stress disorder Psychopharmacology (Berl). 2017 Aug; 234(15):2245-2257. . View in PubMed
  • A phase 3 trial of IV immunoglobulin for Alzheimer disease Neurology. 2017 May 02; 88(18):1768-1775. . View in PubMed
  • Telephone Problem Solving for Service Members with Mild Traumatic Brain Injury: A Randomized, Clinical Trial J Neurotrauma. 2017 01 15; 34(2):313-321. . View in PubMed
  • EU/US/CTAD Task Force: Lessons Learned from Recent and Current Alzheimer’s Prevention Trials J Prev Alzheimers Dis. 2017; 4(2):116-124. . View in PubMed
  • Cross-validation of optimized composites for preclinical Alzheimer’s disease Alzheimers Dement (N Y). 2017 Jan; 3(1):123-129. . View in PubMed
  • Visual Determination of Conjugate Eye Deviation on Computed Tomography Scan Predicts Diagnosis of Stroke Code Patients J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2809-2813. . View in PubMed
  • Accuracy of Stroke Diagnosis in Telestroke-Guided Tissue Plasminogen Activator Patients J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2942-2946. . View in PubMed
  • Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2) Stroke. 2016 12; 47(12):2888-2895. . View in PubMed
  • Changes in Neuropsychiatric Inventory Associated with Semagacestat Treatment of Alzheimer’s Disease J Alzheimers Dis. 2016 08 10; 54(1):373-81. . View in PubMed
  • Neurocognitive Models of Medical Decision-Making Capacity in Traumatic Brain Injury Across Injury Severity J Head Trauma Rehabil. 2016 May-Jun; 31(3):E49-59. . View in PubMed
  • Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury Neuropsychopharmacology. 2016 Apr; 41(5):1191-8. . View in PubMed
  • Accuracy of First Recorded “Last Known Normal” Times of Stroke Code Patients J Stroke Cerebrovasc Dis. 2015 Nov; 24(11):2467-73. . View in PubMed
  • Feasibility and Safety of Using External Counterpulsation to Augment Cerebral Blood Flow in Acute Ischemic Stroke-The Counterpulsation to Upgrade Forward Flow in Stroke (CUFFS) Trial J Stroke Cerebrovasc Dis. 2015 Nov; 24(11):2596-604. . View in PubMed
  • A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease Neurology. 2015 Oct 20; 85(16):1383-91. . View in PubMed
  • Mental Disorders, Comorbidity, and Pre-enlistment Suicidal Behavior Among New Soldiers in the US. Army: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Suicide Life Threat Behav. 2015 Oct; 45(5):588-599. . View in PubMed
  • The “DeyeCOM Sign”: Predictive Value in Acute Stroke Code Evaluations J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1299-304. . View in PubMed
  • Defining mild stroke: outcomes analysis of treated and untreated mild stroke patients J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1276-81. . View in PubMed
  • Alzheimers Res Ther. 2015; 7(1):36. . View in PubMed
  • Prevalence and correlates of suicidal behavior among new soldiers in the US. Army: results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Depress Anxiety. 2015 Jan; 32(1):3-12. . View in PubMed
  • Alzheimer’s disease progression by geographical region in a clinical trial setting Alzheimers Res Ther. 2015; 7(1):43. . View in PubMed
  • Association of Hispanic ethnicity with acute ischemic stroke care processes and outcomes Ethn Dis. 2015; 25(1):19-23. . View in PubMed
  • Concussion treatment after combat trauma: development of a telephone based, problem solving intervention for service members Contemp Clin Trials. 2015 Jan; 40:54-62. . View in PubMed
  • Comparing recruitment, retention, and safety reporting among geographic regions in multinational Alzheimer’s disease clinical trials Alzheimers Res Ther. 2015; 7(1):39. . View in PubMed
  • Estimating long-term multivariate progression from short-term data Alzheimers Dement. 2014 Oct; 10(5 Suppl):S400-10. . View in PubMed
  • Dramatic decline of respiratory illness among US military recruits after the renewed use of adenovirus vaccines Clin Infect Dis. 2014 Oct; 59(7):962-8. . View in PubMed
  • The Alzheimer’s disease cooperative study prevention instrument project: longitudinal outcome of behavioral measures as predictors of cognitive decline Dement Geriatr Cogn Dis Extra. 2014 Sep-Dec; 4(3):509-16. . View in PubMed
  • The preclinical Alzheimer cognitive composite: measuring amyloid-related decline JAMA Neurol. 2014 Aug; 71(8):961-70. . View in PubMed
  • Individuals with chronic traumatic brain injury improve walking speed and mobility with intensive mobility training Arch Phys Med Rehabil. 2014 Aug; 95(8):1454-60. . View in PubMed
  • Self-reported smoking and musculoskeletal overuse injury among male and female US. Marine Corps recruits. Mil Med. 2014 Jul; 179(7):735-43. . View in PubMed
  • A two-site pilot randomized 3 day trial of high dose left prefrontal repetitive transcranial magnetic stimulation (rTMS) for suicidal inpatients Brain Stimul. 2014 May-Jun; 7(3):421-31. . View in PubMed
  • Imaging negative stroke: diagnoses and outcomes in intravenous tissue plasminogen activator-treated patients J Stroke Cerebrovasc Dis. 2014 May-Jun; 23(5):1046-50. . View in PubMed
  • Does symptom onset to primary stroke center time goals affect stroke outcome? J Stroke Cerebrovasc Dis. 2014 May-Jun; 23(5):993-1000.. View in PubMed
  • Accounting for functional loss in Alzheimer’s disease and dementia with Lewy bodies: beyond cognition Alzheimers Dement. 2014 Mar; 10(2):171-8. . View in PubMed
  • Pooled assessment of computed tomography interpretation by vascular neurologists in the STRokE DOC telestroke network J Stroke Cerebrovasc Dis. 2014 Mar; 23(3):511-5. . View in PubMed
  • Phase 3 trials of solanezumab for mild-to-moderate Alzheimer’s disease N Engl J Med. 2014 Jan 23; 370(4):311-21. . View in PubMed
  • Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes Neurology. 2014 Jan 07; 82(1):63-9. . View in PubMed
  • Parametric comparisons of intracranial mechanical responses from three validated finite element models of the human head Ann Biomed Eng. 2014 Jan; 42(1):11-24. . View in PubMed
  • Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol Int J Stroke. 2014 Jan; 9(1):117-25. . View in PubMed
  • Epidemiology of pathogen-specific respiratory infections among three US populations PLoS One. 2014; 9(12):e114871. . View in PubMed
  • Weight patterns before and after total joint arthroplasty and characteristics associated with weight change Perm J. 2014; 18(1):25-31. . View in PubMed
  • Trends in antihypertensive drug prescription patterns among ambulatory stroke patients in the United States, 2000-2009 J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):e568-75. . View in PubMed
  • Diffusion-weighted imaging-fluid attenuated inversion recovery mismatch in nocturnal stroke patients with unknown time of onset J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):972-7. . View in PubMed
  • A phase 3 trial of semagacestat for treatment of Alzheimer’s disease N Engl J Med. 2013 Jul 25; 369(4):341-50. . View in PubMed
  • Determinants of Pneumonia Risk During Endovascular Hypothermia Ther Hypothermia Temp Manag. 2013 Mar; 3(1):24-27. . View in PubMed
  • Effect of study partner on the conduct of Alzheimer disease clinical trials Neurology. 2013 Jan 15; 80(3):282-8. . View in PubMed
  • The association of self-reported measures with poor training outcomes among male and female US. Navy recruits. Mil Med. 2013 Jan; 178(1):43-9. . View in PubMed
  • Effects of varying duty cycle and pulse width on high-intensity focused ultrasound (HIFU)-induced transcranial thrombolysis J Ther Ultrasound. 2013; 1:18. . View in PubMed
  • CT interpretation in a telestroke network: agreement among a spoke radiologist, hub vascular neurologist, and hub neuroradiologist Stroke. 2012 Nov; 43(11):3095-7. . View in PubMed
  • Intravenous tissue plasminogen activator for patients with minor ischemic stroke J Stroke Cerebrovasc Dis. 2012 Nov; 21(8):732-6. . View in PubMed
  • Late night activity regarding stroke codes: LuNAR strokes Int J Stroke. 2012 Aug; 7(6):473-6. . View in PubMed
  • Age and rate of cognitive decline in Alzheimer disease: implications for clinical trials Arch Neurol. 2012 Jul; 69(7):901-5. . View in PubMed
  • Determinants of effective cooling during endovascular hypothermia Neurocrit Care. 2012 Jun; 16(3):413-20. . View in PubMed
  • Assessment of long-term outcomes for the STRokE DOC telemedicine trial J Stroke Cerebrovasc Dis. 2012 May; 21(4):259-64. . View in PubMed
  • Efficacy of telemedicine for stroke: pooled analysis of the Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) and STRokE DOC Arizona telestroke trials Telemed J E Health. 2012 Apr; 18(3):230-7. . View in PubMed
  • Incidence of new-onset seizures in mild to moderate Alzheimer disease Arch Neurol. 2012 Mar; 69(3):368-72. . View in PubMed
  • Evaluating transdiagnostic treatment for distress and impairment in veterans: a multi-site randomized controlled trial of Acceptance and Commitment Therapy Contemp Clin Trials. 2012 Jan; 33(1):116-23. . View in PubMed
  • Comprehensive stroke centers and the ‘weekend effect’: the SPOTRIAS experience Cerebrovasc Dis. 2012; 34(5-6):424-9. . View in PubMed
  • Two-hour improvement of patients in the National Institute of Neurological Disorders and Stroke trials and prediction of final outcome Stroke. 2011 Nov; 42(11):3163-7. . View in PubMed
  • Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease Arch Gen Psychiatry. 2011 Aug; 68(8):853-61. . View in PubMed
  • Adding delayed recall to the Alzheimer Disease Assessment Scale is useful in studies of mild cognitive impairment but not Alzheimer disease Alzheimer Dis Assoc Disord. 2011 Apr-Jun; 25(2):122-7. . View in PubMed
  • Therapeutic hypothermia is associated with a decrease in urine output in acute stroke patients Resuscitation. 2010 Dec; 81(12):1642-7. . View in PubMed
  • Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial JAMA. 2010 Nov 03; 304(17):1903-11. . View in PubMed
  • Alberta Stroke Program Early CT Score (ASPECTS) in patients with wake-up stroke J Stroke Cerebrovasc Dis. 2010 Nov-Dec; 19(6):475-9. . View in PubMed
  • Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results Stroke. 2010 Oct; 41(10):2265-70. . View in PubMed
  • Influence of apolipoprotein E varepsilon4 on rates of cognitive and functional decline in mild cognitive impairment Alzheimers Dement. 2010 Sep; 6(5):412-9. . View in PubMed
  • Gender differences in acute stroke treatment: the University of California San Diego experience Stroke. 2010 Aug; 41(8):1755-7. . View in PubMed
  • Analysis of the National Institute of Neurological Disorders and Stroke tissue plasminogen activator studies following European Cooperative Acute Stroke Study III patient selection criteria J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):290-3. . View in PubMed
  • Stroke team remote evaluation using a digital observation camera in Arizona: the initial mayo clinic experience trial Stroke. 2010 Jun; 41(6):1251-8. . View in PubMed
  • Clinical Core of the Alzheimer’s Disease Neuroimaging Initiative: progress and plans Alzheimers Dement. 2010 May; 6(3):239-46. . View in PubMed
  • Prevalence and psychological correlates of traumatic brain injury in operation iraqi freedom J Head Trauma Rehabil. 2010 Jan-Feb; 25(1):1-8. . View in PubMed
  • MRI substudy participation in Alzheimer disease (AD) clinical trials: baseline comparability of a substudy sample to entire study population Alzheimer Dis Assoc Disord. 2009 Oct-Dec; 23(4):333-6. . View in PubMed
  • Injury-specific predictors of posttraumatic stress disorder Injury. 2009 Sep; 40(9):1004-10. . View in PubMed
  • Characteristics and performance of a modified version of the ADCS-CGIC CIBIC+ for mild cognitive impairment clinical trials Alzheimer Dis Assoc Disord. 2009 Jul-Sep; 23(3):260-7. . View in PubMed
  • National Institutes of Health Stroke Scale certification is reliable across multiple venues Stroke. 2009 Jul; 40(7):2507-11. . View in PubMed
  • Clinical interview assessment of financial capacity in older adults with mild cognitive impairment and Alzheimer’s disease J Am Geriatr Soc. 2009 May; 57(5):806-14. . View in PubMed
  • Psychological correlates of battle and nonbattle injury among Operation Iraqi Freedom veterans Mil Med. 2009 Mar; 174(3):224-31. . View in PubMed
  • Plasma urate and progression of mild cognitive impairment Neurodegener Dis. 2009; 6(1-2):23-8. . View in PubMed
  • Can comprehensive stroke centers erase the ‘weekend effect’? Cerebrovasc Dis. 2009; 27(2):107-13.. View in PubMed
  • In vitro sonothrombolysis with duplex ultrasound: first results using a simplified model Cerebrovasc Dis. 2009; 28(4):365-70. . View in PubMed
  • Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study Lancet Neurol. 2008 Sep; 7(9):787-95. . View in PubMed
  • Awareness of deficits in financial abilities in patients with mild cognitive impairment: going beyond self-informant discrepancy Am J Geriatr Psychiatry. 2008 Aug; 16(8):650-9. . View in PubMed
  • Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease Arch Neurol. 2008 Aug; 65(8):1031-8. . View in PubMed
  • Reliability of site-independent telemedicine when assessed by telemedicine-naive stroke practitioners J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):181-6. . View in PubMed
  • The first puff: forces in smoking initiation among Californians of Korean descent Nicotine Tob Res. 2007 Dec; 9(12):1277-86. . View in PubMed
  • Diffusion of cancer education information through a Latino community health advisor program Prev Med. 2007 Aug-Sep; 45(2-3):135-8. . View in PubMed
  • Quetiapine for agitation or psychosis in patients with dementia and parkinsonism Neurology. 2007 Apr 24; 68(17):1356-63. . View in PubMed
  • An expedited code stroke protocol is feasible and safe Stroke. 2006 Dec; 37(12):2935-9. . View in PubMed
  • ADCS Prevention Instrument Project: ADCS-clinicians’ global impression of change scales (ADCS-CGIC), self-rated and study partner-rated versions Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S124-38. . View in PubMed
  • ADCS Prevention Instrument Project: the Mail-In Cognitive Function Screening Instrument (MCFSI) Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S170-8. . View in PubMed
  • ADCS Prevention Instrument Project: behavioral measures in primary prevention trials Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S147-51. . View in PubMed
  • A mixed-effects regression model for three-level ordinal response data Stat Med. 2005 Nov 15; 24(21):3331-45. . View in PubMed
  • Divalproex sodium in nursing home residents with possible or probable Alzheimer Disease complicated by agitation: a randomized, controlled trial Am J Geriatr Psychiatry. 2005 Nov; 13(11):942-9. . View in PubMed
  • NIHSS training and certification using a new digital video disk is reliable Stroke. 2005 Nov; 36(11):2446-9. . View in PubMed
  • Axonopathy and transport deficits early in the pathogenesis of Alzheimer’s disease Science. 2005 Feb 25; 307(5713):1282-8. . View in PubMed
  • J Natl Med Assoc. 2003 Jun; 95(6):423-32. . View in PubMed
  • Heterotopia of the tonsil J Laryngol Otol. 1996 Jun; 110(6):611-2. . View in PubMed

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