Keck School Faculty

Rex A. Moats

Rex A. Moats

Associate Professor of Research Pathology and Radiology
Scientific Director of Small Animal Research
Pediatrics
CHL Mail Stop 81 Off Campus Los Angeles

Development of an ultrafast brain MR neuronavigation protocol for ventricular shunt placement J Neurosurg. 2022 Jun 10; 1-7. . View in PubMed

Imaging Pulmonary Blood Vessels and Ventilation-Perfusion Mismatch in COVID-19 Mol Imaging Biol. 2022 08; 24(4):526-536. . View in PubMed

Distribution of 14C-Latanoprost Following a Single Intracameral Administration Versus Repeated Topical Administration Ophthalmol Ther. 2020 Dec; 9(4):929-940. . View in PubMed

Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome Thorax. 2020 06; 75(6):486-493. . View in PubMed

MEASUREMENT OF THE HYDRAULIC CONDUCTIVITY OF THE VITREOUS HUMOR J Porous Media. 2020; 23(2):195-206. . View in PubMed

Diffusive Transport in the Vitreous Humor: Experimental and Analytical Studies J Heat Transfer. 2019 May; 141(5):050801. . View in PubMed

Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma PLoS One. 2019; 14(1):e0206394. . View in PubMed

Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation Sci Rep. 2019 03 28; 9(1):5296. . View in PubMed

Discs large 1 controls daughter-cell polarity after cytokinesis in vertebrate morphogenesis Proc Natl Acad Sci U S A. 2018 11 13; 115(46):E10859-E10868. . View in PubMed

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development Sci Rep. 2018 05 29; 8(1):8334. . View in PubMed

Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma Mol Ther Oncolytics. 2017 Mar 17; 4:67-76. . View in PubMed

Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model Stem Cells Transl Med. 2017 06; 6(6):1522-1532. . View in PubMed

Intestinal adaptation in proximal and distal segments: Two epithelial responses diverge after intestinal separation Surgery. 2017 04; 161(4):1016-1027. . View in PubMed

Structural and Functional Characterization of Human Stem-Cell-Derived Retinal Organoids by Live Imaging Invest Ophthalmol Vis Sci. 2017 07 01; 58(9):3311-3318. . View in PubMed

PID1 increases chemotherapy-induced apoptosis in medulloblastoma and glioblastoma cells in a manner that involves NF? B. Sci Rep. 2017 04 11; 7(1):835.. View in PubMed

An allograft mouse model for the study of hearing loss secondary to vestibular schwannoma growth J Neurooncol. 2016 08; 129(1):47-56. . View in PubMed

BarTeL, a Genetically Versatile, Bioluminescent and Granule Neuron Precursor-Targeted Mouse Model for Medulloblastoma PLoS One. 2016; 11(6):e0156907. . View in PubMed

A corrole nanobiologic elicits tissue-activated MRI contrast enhancement and tumor-targeted toxicity J Control Release. 2015 Nov 10; 217:92-101. . View in PubMed

Increased alveolar soluble annexin V promotes lung inflammation and fibrosis Eur Respir J. 2015 Nov; 46(5):1417-29. . View in PubMed

Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration Am J Physiol Gastrointest Liver Physiol. 2015 Aug 01; 309(3):G135-45. . View in PubMed

Dynamic imaging of the growth plate cartilage reveals multiple contributors to skeletal morphogenesis Nat Commun. 2015 Apr 13; 6:6798. . View in PubMed

Juvenile skeletogenesis in anciently diverged sea urchin clades Dev Biol. 2015 Apr 01; 400(1):148-58. . View in PubMed

Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction Cancer Gene Ther. 2015 Jan; 22(1):55-61. . View in PubMed

Cellular uptake and cytotoxicity of a near-IR fluorescent corrole-TiO2 nanoconjugate J Inorg Biochem. 2014 Nov; 140:39-44. . View in PubMed

Integrin a2ß1 targeted GdVO4:Eu ultrathin nanosheet for multimodal PET/MR imaging Biomaterials. 2014 Oct; 35(30):8649-58. . View in PubMed

The synthesis of lanthanide-doped GdVO4 ultrathin nanosheets with great optical and paramagnetic properties for FRET biodetection and in vivo MR imaging J Mater Chem B. 2014 Jul 07; 2(25):3998-4007. . View in PubMed

Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use Stem Cells Transl Med. 2013 Oct; 2(10):766-75. . View in PubMed

Functionalized magnetonanoparticles in visualization of intracranial tumors on MRI Mol Imaging Biol. 2013 Jun; 15(3):299-306. . View in PubMed

Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies Sci Transl Med. 2013 May 08; 5(184):184ra59. . View in PubMed

Decorating metal oxide surfaces with fluorescent chlorosulfonated corroles Inorg Chem. 2013 May 06; 52(9):4774-6. . View in PubMed

Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma Gene Ther. 2013 Feb; 20(2):143-50. . View in PubMed

Imaging brain neuronal activity using functionalized magnetonanoparticles and MRI Brain Topogr. 2012 Oct; 25(4):374-88. . View in PubMed

Novel cell lines established from pediatric brain tumors J Neurooncol. 2012 Apr; 107(2):269-80. . View in PubMed

Automatic abdominal fat assessment in obese mice using a segmental shape model J Magn Reson Imaging. 2011 Oct; 34(4):866-73. . View in PubMed

Adipose segmentation in small animals at 7T: a preliminary study BMC Genomics. 2010 Dec 01; 11 Suppl 3:S9. . View in PubMed

Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model PLoS One. 2009 Sep 29; 4(9):e7218. . View in PubMed

S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model Hepatology. 2009 Aug; 50(2):462-71. . View in PubMed

Shape-aided kidney extraction in MR urography Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:5781-4. . View in PubMed

Biglycan overexpression on tooth enamel formation in transgenic mice Anat Rec (Hoboken). 2008 Oct; 291(10):1246-53. . View in PubMed

Corticotomy-/osteotomy-assisted tooth movement microCTs differ J Dent Res. 2008 Sep; 87(9):861-7. . View in PubMed

Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy Epilepsia. 2008 Aug; 49(8):1419-30. . View in PubMed

Influence of iron chelation on R1 and R2 calibration curves in gerbil liver and heart Magn Reson Med. 2008 Jul; 60(1):82-9. . View in PubMed

The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation Cancer Res. 2007 Oct 01; 67(19):9346-55. . View in PubMed

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence Cancer Res. 2007 Aug 01; 67(15):7525-33. . View in PubMed

Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy Exp Hematol. 2007 Jul; 35(7):1069-73. . View in PubMed

Antioxidant-mediated effects in a gerbil model of iron overload Acta Haematol. 2007; 118(4):193-9. . View in PubMed

Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil Transl Res. 2006 Nov; 148(5):272-80. . View in PubMed

Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice Cancer Res. 2006 Sep 01; 66(17):8430-8. . View in PubMed

Multimodal imaging analysis of tumor progression and bone resorption in a murine cancer model J Comput Assist Tomogr. 2006 May-Jun; 30(3):525-34. . View in PubMed

Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide Mol Imaging Biol. 2006 Jan-Feb; 8(1):9-15. . View in PubMed

Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging Phys Med Biol. 2005 Dec 07; 50(23):5421-41. . View in PubMed

Inter-individual variation in brain phenylalanine concentration in patients with PKU is not caused by genetic variation in the 4F2hc/LAT1 complex Mol Genet Metab. 2005 Dec; 86 Suppl 1:S119-23. . View in PubMed

Cardiac iron determines cardiac T2*, T2, and T1 in the gerbil model of iron cardiomyopathy Circulation. 2005 Jul 26; 112(4):535-43. . View in PubMed

Neonatal gene therapy of MPS I mice by intravenous injection of a lentiviral vector Mol Ther. 2005 May; 11(5):776-89. . View in PubMed

Physiology and pathophysiology of iron cardiomyopathy in thalassemia Ann N Y Acad Sci. 2005; 1054:386-95. . View in PubMed

Assessing growth and response to therapy in murine tumor models Methods Mol Med. 2005; 111:335-50. . View in PubMed

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts Cancer Res. 2004 Nov 01; 64(21):8009-14. . View in PubMed

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis Nucl Med Biol. 2004 Feb; 31(2):179-89. . View in PubMed

Neuropsychological outcome of subjects participating in the PKU adult collaborative study: a preliminary review J Inherit Metab Dis. 2004; 27(5):549-66. . View in PubMed

Brain phenylalanine concentrations in phenylketonuria: research and treatment of adults Pediatrics. 2003 Dec; 112(6 Pt 2):1575-9. . View in PubMed

Micro-MRI at 117 T of a murine brain tumor model using delayed contrast enhancement. Mol Imaging. 2003 Jul; 2(3):150-8. . View in PubMed

Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice Biotechniques. 2003 Jun; 34(6):1184-8. . View in PubMed

Large neutral amino acid therapy and phenylketonuria: a promising approach to treatment Mol Genet Metab. 2003 Jun; 79(2):110-3. . View in PubMed

Danger of high-protein dietary supplements to persons with hyperphenylalaninaemia J Inherit Metab Dis. 2003; 26(4):339-42. . View in PubMed

Craniosynostosis in transgenic mice overexpressing Nell-1 J Clin Invest. 2002 Sep; 110(6):861-70. . View in PubMed

Blood-brain phenylalanine relationships in persons with phenylketonuria Pediatrics. 2000 Nov; 106(5):1093-6. . View in PubMed

High resolution magnetic resonance imaging of the brain in the dy/dy mouse with merosin-deficient congenital muscular dystrophy Neuromuscul Disord. 2000 Jun; 10(4-5):292-8. . View in PubMed

In vivo visualization of gene expression using magnetic resonance imaging Nat Biotechnol. 2000 Mar; 18(3):321-5. . View in PubMed

Brain phenylalanine concentration in the management of adults with phenylketonuria J Inherit Metab Dis. 2000 Feb; 23(1):7-14. . View in PubMed

Magnetic resonance imaging for the evaluation of a novel metastatic orthotopic model of human neuroblastoma in immunodeficient mice Clin Exp Metastasis. 2000; 18(6):455-61. . View in PubMed

Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases Neurology. 1998 Apr; 50(4):1033-40. . View in PubMed

Evaluation of automated MR spectroscopy: application in Alzheimer disease AJNR Am J Neuroradiol. 1995 Oct; 16(9):1779-82. . View in PubMed

Added value of automated clinical proton MR spectroscopy of the brain J Comput Assist Tomogr. 1995 May-Jun; 19(3):480-91. . View in PubMed

Probable Alzheimer disease: diagnosis with proton MR spectroscopy Radiology. 1995 Apr; 195(1):65-72. . View in PubMed

Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities Radiology. 1994 Nov; 193(2):457-63. . View in PubMed

Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease Magn Reson Med. 1994 Jul; 32(1):110-5. . View in PubMed

Automated single-voxel proton MRS: technical development and multisite verification Magn Reson Med. 1994 Apr; 31(4):365-73. . View in PubMed

Scyllo-inositol depletion in hepatic encephalopathy Life Sci. 1994; 54(20):1507-12. . View in PubMed

Decrease in cerebral inositols in rats and humans Biochem J. 1993 Oct 01; 295 ( Pt 1):15-8. . View in PubMed

Alzheimer disease: depiction of increased cerebral myo-inositol with proton MR spectroscopy Radiology. 1993 May; 187(2):433-7. . View in PubMed

Ester and ketone components of aggregation pheromone ofDrosophila hydei (Diptera: Drosophilidae) J Chem Ecol. 1987 Mar; 13(3):451-62. . View in PubMed

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