Keck School Faculty

Rob Scot McConnell

Rob Scot McConnell

Professor of Population and Public Health Sciences
Medicine
SSB 230D 2001 N. Soto Street Health Sciences Campus Los Angeles

Secondhand nicotine vaping at home and respiratory symptoms in young adults Thorax. 2022 Jul; 77(7):663-668. . View in PubMed

The Effects of Co-Exposure to Extremes of Heat and Particulate Air Pollution on Mortality in California: Implications for Climate Change Am J Respir Crit Care Med. 2022 Jun 21. . View in PubMed

Exposure models for particulate matter elemental concentrations in Southern California Environ Int. 2022 07; 165:107247. . View in PubMed

Temperature variability associations with cardiovascular and respiratory emergency department visits in Dhaka, Bangladesh Environ Int. 2022 06; 164:107267. . View in PubMed

Exposure to per- and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis Environ Health Perspect. 2022 04; 130(4):46001. . View in PubMed

Prenatal Exposure to Air Pollution and Autism Spectrum Disorder: Sensitive Windows of Exposure and Sex Differences Environ Health Perspect. 2022 01; 130(1):17008. . View in PubMed

Prenatal exposure to persistent organic pollutants and childhood obesity: A systematic review and meta-analysis of human studies Obes Rev. 2022 01; 23 Suppl 1:e13383. . View in PubMed

Evidence of susceptibility to autism risks associated with early life ambient air pollution: A systematic review Environ Res. 2022 05 15; 208:112590. . View in PubMed

Near-roadway air pollution, immune cells and adipokines among obese young adults Environ Health. 2022 03 19; 21(1):36. . View in PubMed

Tobacco-free Nicotine - New Name, Same Scheme? N Engl J Med. 2021 Dec 23; 385(26):2406-2408.. View in PubMed

Prenatal and childhood exposure to air pollution and traffic and the risk of liver injury in European children Environ Epidemiol. 2021 Jun; 5(3):e153. . View in PubMed

In Utero Exposure to Mercury Is Associated With Increased Susceptibility to Liver Injury and Inflammation in Childhood Hepatology. 2021 09; 74(3):1546-1559. . View in PubMed

E-cigarette and cigarette purchasing among young adults before and after implementation of California's tobacco 21 policy Tob Control. 2021 03; 30(2):206-211. . View in PubMed

Contribution of tailpipe and non-tailpipe traffic sources to quasi-ultrafine, fine and coarse particulate matter in southern California J Air Waste Manag Assoc. 2021 02; 71(2):209-230. . View in PubMed

Risk of lead exposure, subcortical brain structure, and cognition in a large cohort of 9- to 10-year-old children PLoS One. 2021; 16(10):e0258469. . View in PubMed

Association of Political Party Affiliation With Physical Distancing Among Young Adults During the COVID-19 Pandemic JAMA Intern Med. 2021 03 01; 181(3):399-403. . View in PubMed

Association of Local Variation in Neighborhood Disadvantage in Metropolitan Areas With Youth Neurocognition and Brain Structure JAMA Pediatr. 2021 08 01; 175(8):e210426. . View in PubMed

Prevalence of Young Adult Vaping, Substance Vaped, and Purchase Location Across Five Categories of Vaping Devices Nicotine Tob Res. 2021 05 04; 23(5):829-835. . View in PubMed

Young adult perspectives on their respiratory health symptoms since vaping Subst Abus. 2021; 42(4):428-432. . View in PubMed

Association of Outdoor Ambient Fine Particulate Matter With Intracellular White Matter Microstructural Properties Among Children JAMA Netw Open. 2021 12 01; 4(12):e2138300. . View in PubMed

Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children Hepatology. 2020 11; 72(5):1758-1770. . View in PubMed

Fine particulate matter exposure during childhood relates to hemispheric-specific differences in brain structure Environ Int. 2020 10; 143:105933. . View in PubMed

E-cigarette Product Characteristics and Subsequent Frequency of Cigarette Smoking Pediatrics. 2020 05; 145(5). . View in PubMed

Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach Environ Int. 2020 01; 134:105220. . View in PubMed

Association of lead-exposure risk and family income with childhood brain outcomes Nat Med. 2020 01; 26(1):91-97. . View in PubMed

Risk factors associated with subsequent initiation of cigarettes and e-cigarettes in adolescence: A structural equation modeling approach Drug Alcohol Depend. 2020 02 01; 207:107676. . View in PubMed

Assessment of Nicotine and Cannabis Vaping and Respiratory Symptoms in Young Adults JAMA Netw Open. 2020 12 01; 3(12):e2030189. . View in PubMed

Prevalence of Electronic Cigarette Dependence Among Youth and Its Association With Future Use JAMA Netw Open. 2020 02 05; 3(2):e1921513. . View in PubMed

Sexual minority tobacco use disparities across adolescence and the transition to young adulthood Drug Alcohol Depend. 2020 12 01; 217:108298. . View in PubMed

Trends in the Age of Cigarette Smoking Initiation Among Young Adults in the US From 2002 to 2018 JAMA Netw Open. 2020 10 01; 3(10):e2019022. . View in PubMed

The Potential Effects of Policy-driven Air Pollution Interventions on Childhood Lung Development Am J Respir Crit Care Med. 2020 02 15; 201(4):438-444. . View in PubMed

Association of Fish Consumption and Mercury Exposure During Pregnancy With Metabolic Health and Inflammatory Biomarkers in Children JAMA Netw Open. 2020 03 02; 3(3):e201007. . View in PubMed

Association of the Built Environment With Childhood Psychosocial Stress JAMA Netw Open. 2020 10 01; 3(10):e2017634. . View in PubMed

Predicting Fine Spatial Scale Traffic Noise Using Mobile Measurements and Machine Learning Environ Sci Technol. 2020 10 20; 54(20):12860-12869. . View in PubMed

Digital media use and subsequent cannabis and tobacco product use initiation among adolescents Drug Alcohol Depend. 2020 07 01; 212:108017. . View in PubMed

Sex-specific associations of autism spectrum disorder with residential air pollution exposure in a large Southern California pregnancy cohort Environ Pollut. 2019 Nov; 254(Pt A):113010. . View in PubMed

Gestational diabetes mellitus, prenatal air pollution exposure, and autism spectrum disorder Environ Int. 2019 12; 133(Pt A):105110. . View in PubMed

Flavored E-cigarette Use and Progression of Vaping in Adolescents Pediatrics. 2019 11; 144(5). . View in PubMed

Associations of gestational diabetes mellitus with residential air pollution exposure in a large Southern California pregnancy cohort Environ Int. 2019 09; 130:104933. . View in PubMed

Evaluating the predictive value of measures of susceptibility to tobacco and alternative tobacco products Addict Behav. 2019 09; 96:50-55. . View in PubMed

Ethnic Differences in Patterns of Cigarette and E-Cigarette Use Over Time Among Adolescents J Adolesc Health. 2019 09; 65(3):359-365. . View in PubMed

Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity Environ Int. 2019 09; 130:104935. . View in PubMed

Tobacco Retail Licensing and Youth Product Use Pediatrics. 2019 02; 143(2). . View in PubMed

Electronic Cigarette and Cigarette Social Environments and Ever Use of Each Product: A Prospective Study of Young Adults in Southern California Nicotine Tob Res. 2019 09 19; 21(10):1347-1354. . View in PubMed

Effects of policy-driven hypothetical air pollutant interventions on childhood asthma incidence in southern California Proc Natl Acad Sci U S A. 2019 08 06; 116(32):15883-15888. . View in PubMed

Association of Changes in Air Quality With Incident Asthma in Children in California, 1993-2014 JAMA. 2019 05 21; 321(19):1906-1915. . View in PubMed

Tobacco Marketing and Subsequent Use of Cigarettes, E-Cigarettes, and Hookah in Adolescents Nicotine Tob Res. 2019 06 21; 21(7):926-932. . View in PubMed

RISK EFFECTS OF NEAR-ROADWAY POLLUTANTS AND ASTHMA STATUS ON BRONCHITIC SYMPTOMS IN CHILDREN Environ Epidemiol. 2018 Jun; 2(2). . View in PubMed

E-cigarette Use and Subsequent Smoking Frequency Among Adolescents Pediatrics. 2018 12; 142(6). . View in PubMed

Talking about tobacco on Twitter is associated with tobacco product use Prev Med. 2018 09; 114:54-56. . View in PubMed

Traffic-related air pollution associations with cytokeratin-18, a marker of hepatocellular apoptosis, in an overweight and obese paediatric population Pediatr Obes. 2018 06; 13(6):342-347. . View in PubMed

Air pollution, weight loss and metabolic benefits of bariatric surgery: a potential model for study of metabolic effects of environmental exposures Pediatr Obes. 2018 05; 13(5):312-320. . View in PubMed

Effect of inhaled allergens and air pollutants on childhood rhinitis development Ann Allergy Asthma Immunol. 2018 02; 120(2):212-214. . View in PubMed

Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder J Autism Dev Disord. 2018 01; 48(1):137-150. . View in PubMed

Joint effects of prenatal air pollutant exposure and maternal folic acid supplementation on risk of autism spectrum disorder Autism Res. 2018 01; 11(1):69-80. . View in PubMed

Performance of cigarette susceptibility index among e-cigarette and hookah users Drug Alcohol Depend. 2018 02 01; 183:43-50. . View in PubMed

Characterizing Polytobacco Use Trajectories and Their Associations With Substance Use and Mental Health Across Mid-Adolescence Nicotine Tob Res. 2018 08 14; 20(suppl_1):S31-S38. . View in PubMed

Long-Term Ambient Temperature and Externalizing Behaviors in Adolescents Am J Epidemiol. 2018 09 01; 187(9):1931-1941. . View in PubMed

Type of E-Cigarette Device Used Among Adolescents and Young Adults: Findings From a Pooled Analysis of Eight Studies of 2166 Vapers Nicotine Tob Res. 2018 01 05; 20(2):271-274. . View in PubMed

Emerging exposures of developmental toxicants Curr Opin Pediatr. 2017 Apr; 29(2):218-224. . View in PubMed

Perceived stress and poly-tobacco product use across adolescence: Patterns of association and gender differences J Psychiatr Res. 2017 11; 94:172-179. . View in PubMed

The Effects of Policy-Driven Air Quality Improvements on Children's Respiratory Health Res Rep Health Eff Inst. 2017 Jan; (190):1-75. . View in PubMed

Electronic Cigarette Use and Respiratory Symptoms in Adolescents Am J Respir Crit Care Med. 2017 04 15; 195(8):1043-1049. . View in PubMed

Associations of Electronic Cigarette Nicotine Concentration With Subsequent Cigarette Smoking and Vaping Levels in Adolescents JAMA Pediatr. 2017 12 01; 171(12):1192-1199. . View in PubMed

Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012 JAMA. 2016 Apr 12; 315(14):1491-501. . View in PubMed

Patterns of Alternative Tobacco Product Use: Emergence of Hookah and E-cigarettes as Preferred Products Amongst Youth J Adolesc Health. 2016 Feb; 58(2):181-5. . View in PubMed

Near-Roadway Air Pollution and Coronary Heart Disease: Burden of Disease and Potential Impact of a Greenhouse Gas Reduction Strategy in Southern California Environ Health Perspect. 2016 Feb; 124(2):193-200. . View in PubMed

Does near-roadway air pollution contribute to childhood obesity? Pediatr Obes. 2016 Feb; 11(1):1-3.. View in PubMed

E-cigarettes, Cigarettes, and the Prevalence of Adolescent Tobacco Use Pediatrics. 2016 08; 138(2). . View in PubMed

The E-cigarette Social Environment, E-cigarette Use, and Susceptibility to Cigarette Smoking J Adolesc Health. 2016 07; 59(1):75-80. . View in PubMed

E-Cigarettes and Future Cigarette Use Pediatrics. 2016 07; 138(1). . View in PubMed

Environmental Determinants of Aggression in Adolescents: Role of Urban Neighborhood Greenspace J Am Acad Child Adolesc Psychiatry. 2016 07; 55(7):591-601. . View in PubMed

Momentary Assessment of Psychosocial Stressors, Context, and Asthma Symptoms in Hispanic Adolescents Behav Modif. 2016 Jan; 40(1-2):257-80. . View in PubMed

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults PLoS One. 2016; 11(3):e0150825. . View in PubMed

Psychosocial Factors Associated With Adolescent Electronic Cigarette and Cigarette Use Pediatrics. 2015 Aug; 136(2):308-17. . View in PubMed

Design of a smartphone application to monitor stress, asthma symptoms, and asthma inhaler useAnn Allergy Asthma Immunol. 2015 Apr; 114(4):341-342. e2. . View in PubMed

A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study Environ Health Perspect. 2015 Apr; 123(4):360-6. . View in PubMed

Association of improved air quality with lung development in children N Engl J Med. 2015 Mar 05; 372(10):905-13. . View in PubMed

Flavorings in electronic cigarettes: an unrecognized respiratory health hazard? JAMA. 2014 Dec 17; 312(23):2493-4.. View in PubMed

Associations of children's lung function with ambient air pollution: joint effects of regional and near-roadway pollutants Thorax. 2014 Jun; 69(6):540-7. . View in PubMed

Evaluating children's location using a personal GPS logging instrument: limitations and lessons learned J Expo Sci Environ Epidemiol. 2014 May-Jun; 24(3):244-52. . View in PubMed

Hair Cortisol, Perceived Stress and Dispositional Optimism: A Pilot Study among Adolescents J Trauma Stress Disord Treat. 2014 Mar 18; 3(3):1000126. . View in PubMed

Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene Epidemiology. 2014 Jan; 25(1):44-7. . View in PubMed

Inflammatory cytokine response to ambient particles varies due to field collection procedures Am J Respir Cell Mol Biol. 2013 Apr; 48(4):497-502. . View in PubMed

Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses PLoS One. 2013; 8(5):e64128. . View in PubMed

Traffic-related air pollution, particulate matter, and autism JAMA Psychiatry. 2013 Jan; 70(1):71-7. . View in PubMed

Accuracy of a new time-resolved step counter in children Pediatr Exerc Sci. 2012 Nov; 24(4):622-33. . View in PubMed

Childhood air pollutant exposure and carotid artery intima-media thickness in young adults Circulation. 2012 Sep 25; 126(13):1614-20. . View in PubMed

Organized physical activity in young school children and subsequent 4-year change in body mass index Arch Pediatr Adolesc Med. 2012 Aug; 166(8):713-8. . View in PubMed

Predictors of intra-community variation in air quality J Expo Sci Environ Epidemiol. 2012 Mar-Apr; 22(2):135-47. . View in PubMed

Parental stress increases the detrimental effect of traffic exposure on children's lung function Am J Respir Crit Care Med. 2011 Oct 01; 184(7):822-7. . View in PubMed

Residential proximity to freeways and autism in the CHARGE study Environ Health Perspect. 2011 Jun; 119(6):873-7. . View in PubMed

Ethnic differences in the effect of asthma on pulmonary function in children Am J Respir Crit Care Med. 2011 Mar 01; 183(5):596-603. . View in PubMed

Exhaled nitric oxide, susceptibility and new-onset asthma in the Children's Health Study Eur Respir J. 2011 Mar; 37(3):523-31. . View in PubMed

Asthma and school commuting time J Occup Environ Med. 2010 Aug; 52(8):827-8. . View in PubMed

Childhood incident asthma and traffic-related air pollution at home and school Environ Health Perspect. 2010 Jul; 118(7):1021-6. . View in PubMed

Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence Thorax. 2010 Feb; 65(2):139-45. . View in PubMed

Long-term outcome of subcutaneously preserved autologous cranioplasty Neurosurgery. 2009 Sep; 65(3):505-10; discussion 510. . View in PubMed

Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children Thorax. 2009 Mar; 64(3):197-202. . View in PubMed

Parental stress and childhood wheeze in a prospective cohort study J Asthma. 2008 May; 45(4):319-23. . View in PubMed

Use of an electrostatic dust cloth for self-administered home allergen collection Twin Res Hum Genet. 2008 Apr; 11(2):150-5. . View in PubMed

Ozone, oxidant defense genes, and risk of asthma during adolescence Am J Respir Crit Care Med. 2008 Feb 15; 177(4):388-95. . View in PubMed

Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma Am J Respir Crit Care Med. 2007 Dec 15; 176(12):1192-9. . View in PubMed

Relationship between air pollution, lung function and asthma in adolescents Thorax. 2007 Nov; 62(11):957-63. . View in PubMed

The association between contextual socioeconomic factors and prevalent asthma in a cohort of Southern California school children Soc Sci Med. 2007 Oct; 65(8):1792-806. . View in PubMed

Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study Lancet. 2007 Feb 17; 369(9561):571-7. . View in PubMed

Competing definitions of contextual environments Int J Health Geogr. 2006 Dec 07; 5:55. . View in PubMed

Dog ownership enhances symptomatic responses to air pollution in children with asthma Environ Health Perspect. 2006 Dec; 114(12):1910-5. . View in PubMed

Health effects of the 2003 Southern California wildfires on children Am J Respir Crit Care Med. 2006 Dec 01; 174(11):1221-8. . View in PubMed

Regular smoking and asthma incidence in adolescents Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1094-100. . View in PubMed

Bayesian modeling of air pollution health effects with missing exposure data Am J Epidemiol. 2006 Jul 01; 164(1):69-76. . View in PubMed

Predicting residential ozone deficits from nearby traffic Sci Total Environ. 2006 Jun 15; 363(1-3):166-74. . View in PubMed

Mode of delivery is associated with asthma and allergy occurrences in children Ann Epidemiol. 2006 May; 16(5):341-6. . View in PubMed

Traffic, susceptibility, and childhood asthma Environ Health Perspect. 2006 May; 114(5):766-72. . View in PubMed

TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences Am J Respir Crit Care Med. 2005 Dec 15; 172(12):1563-8. . View in PubMed

Childhood asthma and exposure to traffic and nitrogen dioxide Epidemiology. 2005 Nov; 16(6):737-43. . View in PubMed

Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research Environ Health Perspect. 2005 Oct; 113(10):1447-54. . View in PubMed

Surface sampling for endotoxin assessment using electrostatic wiping cloths Ann Occup Hyg. 2005 Jul; 49(5):401-6. . View in PubMed

Educational intervention to control cockroach allergen exposure in the homes of hispanic children in Los Angeles: results of the La Casa study Clin Exp Allergy. 2005 Apr; 35(4):426-33. . View in PubMed

Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study Arch Environ Health. 2004 Oct; 59(10):505-14. . View in PubMed

The effect of air pollution on lung development from 10 to 18 years of age N Engl J Med. 2004 Sep 09; 351(11):1057-67. . View in PubMed

Knowledge of skin test results among parents of asthmatic children J Asthma. 2004 Apr; 41(2):199-204. . View in PubMed

Cockroach counts and house dust allergen concentrations after professional cockroach control and cleaning Ann Allergy Asthma Immunol. 2003 Dec; 91(6):546-52. . View in PubMed

Prospective study of air pollution and bronchitic symptoms in children with asthma Am J Respir Crit Care Med. 2003 Oct 01; 168(7):790-7. . View in PubMed

Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake Am J Epidemiol. 2003 Sep 15; 158(6):576-84. . View in PubMed

Obesity and the risk of newly diagnosed asthma in school-age children Am J Epidemiol. 2003 Sep 01; 158(5):406-15. . View in PubMed

Breathless in Los Angeles: the exhausting search for clean air Am J Public Health. 2003 Sep; 93(9):1494-9. . View in PubMed

Environmental tobacco smoke and absenteeism related to respiratory illness in schoolchildren Am J Epidemiol. 2003 May 15; 157(10):861-9. . View in PubMed

Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children Am J Respir Crit Care Med. 2002 Aug 15; 166(4):457-63. . View in PubMed

Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children Am J Respir Crit Care Med. 2002 Aug 01; 166(3):346-51. . View in PubMed

Association between air pollution and lung function growth in southern California children: results from a second cohort Am J Respir Crit Care Med. 2002 Jul 01; 166(1):76-84. . View in PubMed

Indoor risk factors for asthma in a prospective study of adolescents Epidemiology. 2002 May; 13(3):288-95. . View in PubMed

Asthma in exercising children exposed to ozone: a cohort study Lancet. 2002 Feb 02; 359(9304):386-91. . View in PubMed

The effects of ambient air pollution on school absenteeism due to respiratory illnesses Epidemiology. 2001 Jan; 12(1):43-54. . View in PubMed

Effects of in utero and environmental tobacco smoke exposure on lung function in boys and girls with and without asthma Am J Respir Crit Care Med. 2000 Dec; 162(6):2097-104. . View in PubMed

Sex-specific effects of asthma on pulmonary function in children Am J Respir Crit Care Med. 2000 Nov; 162(5):1723-30. . View in PubMed

Association between air pollution and lung function growth in southern California children Am J Respir Crit Care Med. 2000 Oct; 162(4 Pt 1):1383-90. . View in PubMed

The ACE I allele is associated with increased risk for ruptured intracranial aneurysms J Med Genet. 2000 Jul; 37(7):498-500. . View in PubMed

Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function Thorax. 2000 Apr; 55(4):271-6. . View in PubMed

Air pollution and bronchitic symptoms in Southern California children with asthma Environ Health Perspect. 1999 Sep; 107(9):757-60. . View in PubMed

Organophosphate neuropathy due to methamidophos: biochemical and neurophysiological markers Arch Toxicol. 1999 Aug; 73(6):296-300. . View in PubMed

Subclinical health effects of environmental pesticide contamination in a developing country: cholinesterase depression in children Environ Res. 1999 Aug; 81(2):87-91. . View in PubMed

A theoretical basis for investigating ambient air pollution and children's respiratory health Environ Health Perspect. 1999 Jun; 107 Suppl 3:403-7. . View in PubMed

Determinants of the Spatial Distributions of Elemental Carbon and Particulate Matter in Eight Southern Californian Communities Atmos Environ (1994). 2014 Apr 01; 86:84-92. . View in PubMed

Spatial Variation in Particulate Matter Components over a Large Urban Area Atmos Environ (1994). 2014 Feb 01; 83:211-219. . View in PubMed

Field measurement of plasma and erythrocyte cholinesterases Clin Chim Acta. 1988 Sep 15; 176(3):315-32. . View in PubMed

Measurement of acetylcholinesterase in erythrocytes in the field Clin Chem. 1987 Oct; 33(10):1731-5. . View in PubMed

Dr. Rob McConnell is a physician and environmental epidemiologist, and Professor of Preventive Medicine. He directs the NIH/Environmental Protection Agency-supported Southern California Children’s Environmental Health Center. He has studied the effects of air pollution on children’s health, including the development of asthma and lung function deficits, and early markers for cardiovascular disease. Dr. McConnell has investigated susceptibility to the effects of environmental exposures conferred by psychosocial stress and social factors, exercise, genetics and co-exposures associated with housing conditions. He has interest, in addition, in the development of methods for estimating the burden of disease associated with near-roadway air pollution and for assessing exposure in environmental epidemiology. Currently funded research is focused on environmental determinants of autism and of obesity and its metabolic consequences in children; on respiratory hazards of e-cigarette use; and on the determinants of tobacco product use as a project director in the USC Tobacco Center for Regulatory Science. He co-directs the NIEHS T32 training program in environmental genomics and the Career Development Program of the NIEHS-supported Southern California Environmental Health Sciences Center. Prior to coming to USC, he directed a World Health Organization regional environmental health center for Latin America and the Caribbean. Dr. McConnell is a member of EPA’s Clean Air Scientific Advisory Committee (CASAC) Particulate Matter Panel. He is a fellow of the American Association for the Advancement of Science.

Selected peer-reviewed publications (from over 140):

1. Impact of air pollution on childhood respiratory disease and lung function and asthma.

a. McConnell R, Berhane K, Gilliland F, London SJ, Islam T, Gauderman WJ, Avol E, Margolis HG, Peters JM. Asthma in exercising children exposed to ozone: a cohort study. Lancet. 2002 Feb 2;359(9304):386-91. PubMed PMID: 11844508
b. Gauderman WJ, Vora H, McConnell R, Berhane K, Gilliland F, Thomas D, Lurmann F, Avol E, Kunzli N, Jerrett M, Peters J. Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study. Lancet. 2007 Feb 17;369(9561):571-7. PubMed PMID: 17307103.
c. McConnell R, Islam T, Shankardass K, Jerrett M, Lurmann F, Gilliland F, Gauderman J, Avol E, Künzli N, Yao L, Peters J, Berhane K. Childhood incident asthma and traffic-related air pollution at home and school. Environ Health Perspect. 2010 Jul;118(7):1021-6. PubMed PMID: 20371422; PubMed Central PMCID: PMC2920902.
d. *Urman R, McConnell R, Islam T, Avol EL, Lurmann FW, Vora H, Linn WS, Rappaport EB, Gilliland FD, Gauderman WJ. Associations of children's lung function with ambient air pollution: joint effects of regional and near-roadway pollutants. Thorax. 2014 Jun;69(6):540-7. PubMed PMID: 24253832; PubMed Central PMCID: PMC4191894.
e. Gauderman WJ, Urman R, Avol E, Berhane K, McConnell R, Rappaport E, Chang R, Lurmann F, Gilliland F. Association of improved air quality with lung development in children. N Engl J Med. 2015 Mar 5;372(10):905-13. PubMed PMID: 25738666; PubMed Central PMCID: PMC4430551.

2. Novel risk factors for respiratory disease and their interactions with air pollution that may provide clues to relevant biological pathways.

a. McConnell R, Berhane K, Molitor J, Gilliland F, Künzli N, Thorne PS, Thomas D, Gauderman WJ, Avol E, Lurmann F, Rappaport E, Jerrett M, Peters JM. Dog ownership enhances symptomatic responses to air pollution in children with asthma. Environ Health Perspect. 2006 Dec;114(12):1910-5. PubMed PMID: 17185284; PubMed Central PMCID: PMC1764158.
b. *Shankardass K, McConnell R, Jerrett M, Milam J, Richardson J, Berhane K. Parental stress increases the effect of traffic-related air pollution on childhood asthma incidence. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12406-11. PubMed PMID: 19620729; PubMed Central PMCID: PMC2718368.
c. *Islam T, McConnell R, Gauderman WJ, Berhane K, Avol E, Peters JM,Gilliland FD. Glutathione-S-Transferase (GST) P1, exercise, ozone and asthma incidence in school children. Thorax. 2009 Mar; 64(3):197-202. PubMed PMID: 18988661; PubMed Central PMCID: PMC2738935.
d. *Islam T, Urman R, Gauderman WJ, Milam J, Lurmann F, Shankardass K, Avol E, Gilliland F, McConnell R. Parental Stress Increases the Detrimental Effect of Traffic Exposure on Children's Lung Function. Am J Respir Crit Care Med. 2011 Oct 1;184(7):822-7. PubMed PMID: 21700914; PMCID: PMC3208647.
3. Neurological effects of diverse environmental exposures in studies of children and workers.
a. Rosenstock L, Keifer M, Daniell WE, McConnell R, Claypoole K. Chronic central nervous system effects of acute organophosphate pesticide intoxication. The Pesticide Health Effects Study Group. Lancet. 1991 Jul 27;338(8761):223-7. PubMed PMID: 1676786.
b. *Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R. Residential proximity to freeways and autism in the CHARGE study. Environ Health Perspect. 2011 Jun;119(6):873-7. PubMed PMID: 21156395; PubMed Central PMCID: PMC3114825.
c. *Volk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R. Traffic-related air pollution, particulate matter, and autism. JAMA Psychiatry. 2013 Jan;70(1):71-7. PubMed PMID: 23404082; PubMed Central PMCID: PMC4019010.
d. *Volk HE, Kerin T, Lurmann F, Hertz-Picciotto I, McConnell R, Campbell DB. Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene. Epidemiology. 2014 Jan;25(1):44-7. PubMed PMID: 24240654; PubMed Central PMCID: PMC4019012.

4. Associations of air pollution in children with obesogenic and cardiometabolic outcomes.

a. Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25;126(13):1614-20. PubMed PMID: 22896588; PubMed Central PMCID: PMC3474843.
b. Jerrett M, McConnell R, Wolch J, Chang R, Lam C, Dunton G, Gilliland F, Lurmann F, Islam T, Berhane K. Traffic-related air pollution and obesity formation in children: a longitudinal, multilevel analysis. Environ Health. 2014 Jun 9;13:49. PubMed PMID: 24913018; PubMed Central PMCID: PMC4106205.
c. McConnell R, Shen E, Gilliland FD, Jerrett M, Wolch J, Chang CC, Lurmann F, Berhane K. A longitudinal cohort study of body mass index and childhood exposure to secondhand tobacco smoke and air pollution: the Southern California Children's Health Study. Environ Health Perspect. 2015 Apr;123(4):360-6. PubMed PMID: 25389275; PubMed Central PMCID: PMC4384197.
d. *Ghosh R, Gauderman W, Minor H, Youn H, Lurman F, Cromar K, Chatzi L, Belcher B, Ren Fielding C, McConnell R. Air pollution, weight loss and metabolic benefits of bariatric surgery: A potential model for study of metabolic effects of environmental exposures. International Journal of Pediatric Obesity in press.

5. Emerging risks of e-cigarettes, cigarettes, and other alternative tobacco products

a. *Barrington-Trimis, JL, Samet, JM, McConnell, R. Flavorings in Electronic Cigarettes: An Unrecognized Respiratory Health Hazard? JAMA. 2014 Dec 17;312(23):2493-4.doi:10.1001/jama.2014.14830.
b. *Barrington-Trimis JL, Urman R, Berhane K, Unger JB, Cruz TB, Pentz MA, Samet JM, Leventhal AM, McConnell R. E-Cigarettes and Future Cigarette Use. Pediatrics. 2016;138(1). PubMed PMID: 27296866; PMCID: PMC4925085.
c. *Barrington-Trimis JL, Urman R, Leventhal AM, Gauderman WJ, Cruz TB, Gilreath TD, Howland S, Unger JB, Berhane K, Samet JM, McConnell R. E-cigarettes, Cigarettes, and the Prevalence of Adolescent Tobacco Use. Pediatrics. 2016; 138(2). PubMed PMID: 27401102; PMCID: PNC4960723.
d. McConnell R, Barrington-Trimis JL, Wang K, Urman R, Hong H, Unger J, Samet J, Leventhal A, Berhane K. Electronic-cigarette Use and Respiratory Symptoms in Adolescents. Am J Respir Crit Care Med. 2017;195(8):1043-1049. PubMed PMID: 27806211.

6. Novel methods for assessing burden and cost of disease associated with near-roadway air pollution and applications to engagement of Southern California stakeholders

a. Künzli N, Perez L, Lurmann F, Hricko A, Penfold B, McConnell R. An attributable risk model for exposures assumed to cause both chronic disease and its exacerbations. Epidemiology. 2008;19(2):179-85. PubMed PMID: 18300703
b. *Brandt S, Perez L, Künzli N, Lurmann F, McConnell R. Costs of childhood asthma due to traffic-related pollution in two California communities. European Respiratory Journal. 2012 Aug;40(2):363-70. PubMed PMID: 22267764; PMCID: PMC4396740.
c. *Perez L, Lurman F, Wilson J, Pastor M, Brandt S, Kunzli N, McConnell R. Near-Roadway Pollution and Childhood Asthma: Implications for Developing “Win-Win” Compact Urban Development and Clean Vehicle Strategies. Environ Health Perspect. 2012; 120(11):1619-26. PubMed PMID: 23008270; PMCID: PMC3556611.
d. Brandt, S, Perez, L, Kunzil, N, Lurman, F, Wilson, J, Pastor, McConnell, R. Cost of near-roadway and regional air pollution–attributable childhood asthma in Los Angeles County.Journal of Allergy and Clinical Immunology. 2014,134:5;1028-1035. PubMed PMID: 25439228; PMCID: PMC4257136.
e. *Ghosh R, Lurmann F, Perez L, Penfold B, Brandt S, Wilson J, Milet M, Künzli N, McConnell R. Near-Roadway Air Pollution and Coronary Heart Disease: Burden of Disease and Potential Impact of a Greenhouse Gas Reduction Strategy in Southern California. Environ Health Perspect. 2016 Aug;124(2):193-200. PubMed PMID: 26149207; PMCID: PMC4749075.


*Student or junior faculty mentored by McConnell

A complete list of peer reviewed publications is available at:

http://www.ncbi.nlm.nih.gov/sites/myncbi/rob.mcconnell.1/bibliography/40704438/public/?sort=date&direction= descending
sc ctsi logoPowered by SC CTSI