Rong Lu, PhD

Rong Lu Lab Website

• Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Glioblastoma Tumor Growth by Regulating Mitochondrial Function. bioRxiv. 2025 Oct 22.. View in PubMed
• Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review. J Immunother Cancer. 2025 Jan 16; 13(1).. View in PubMed
• Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. Cell Mol Immunol. 2024 Dec; 21(12):1459-1473.. View in PubMed
• A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm. Mol Oncol. 2024 Oct; 18(10):2333-2337.. View in PubMed
• Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation. J Biol Chem. 2024 05; 300(5):107257.. View in PubMed
• Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation. bioRxiv. 2023 Oct 10.. View in PubMed
• PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma. Cancer Res. 2023 08 01; 83(15):2527-2542.. View in PubMed
• PP2Ac/STRN4 negatively regulates STING-type I IFN signaling in tumor-associated macrophages. J Clin Invest. 2023 03 15; 133(6).. View in PubMed
• Acoustofluidic assembly of primary tumor-derived organotypic cell clusters for rapid evaluation of cancer immunotherapy. J Nanobiotechnology. 2023 Feb 04; 21(1):40.. View in PubMed
• Lineage tracking to reveal the fate of hematopoietic stem cells influenced by Flk2- multipotent progenitors after transplantation. Exp Mol Med. 2023 01; 55(1):205-214.. View in PubMed
• Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism. Nat Commun. 2022 05 03; 13(1):2412.. View in PubMed
• Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. Nat Commun. 2021 11 11; 12(1):6522.. View in PubMed
• Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma. J Neurooncol. 2020 Jun; 148(2):231-244.. View in PubMed
• Clonal tracking using embedded viral barcoding and high-throughput sequencing. Nat Protoc. 2020 04; 15(4):1436-1458.. View in PubMed
• Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1447-1456.. View in PubMed
• Functional compensation between hematopoietic stem cell clones in vivo. EMBO Rep. 2018 08; 19(8).. View in PubMed
• Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants. Blood. 2017 03 16; 129(11):1448-1457.. View in PubMed
• Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate. Nat Commun. 2017 02 22; 8:14533.. View in PubMed
• Transplantation Dose Alters the Differentiation Program of Hematopoietic Stem Cells. Cell Rep. 2016 05 24; 15(8):1848-57.. View in PubMed
• Sleeping beauty wakes up the clonal succession model for homeostatic hematopoiesis. Cell Stem Cell. 2014 Dec 04; 15(6):677-8.. View in PubMed
• Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell. 2014 Apr 03; 14(4):486-499.. View in PubMed
• Discriminating cellular heterogeneity using microwell-based RNA cytometry. Nat Commun. 2014 Mar 25; 5:3451.. View in PubMed
• Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol. 2011 Oct 02; 29(10):928-33.. View in PubMed
• Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature. 2009 Nov 19; 462(7271):358-62.. View in PubMed
• Automated microfluidic chromatin immunoprecipitation from 2,000 cells. Lab Chip. 2009 May 21; 9(10):1365-70.. View in PubMed
• A genomewide functional network for the laboratory mouse. PLoS Comput Biol. 2008 Sep 26; 4(9):e1000165.. View in PubMed
• Dissecting self-renewal in stem cells with RNA interference. Nature. 2006 Aug 03; 442(7102):533-8.. View in PubMed

• McMahon, Andrew
• Murry, Charles