Sargis Sedrakyan

Assistant Professor Of Research Urology

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Education and Training

  • Brooklyn College, CUNY, New York — BS — 06/2003 — Biological Sciences
  • University of Padova & USC, Italy/USA — PhD — 04/2012 — Tissue Engineering and Regenerative Medicine

Research Funding

  • Glomerular endothelial damage: a new role of the lipids in Alport syndrome
    NIH NIDDK · Dec 16, 2023 – Nov 30, 2027 · Role: Principle Investigator

Research Keywords

  • Chronic kidney disease
  • Alport syndrome
  • Focal Segmental Glomerulosclerosis
  • Diabetic Nephropathy
  • Glomerular filtration barrier
  • Proteinuria
  • Lipid metabolism
  • Amniotic fluid stem cells
  • Extracellular vesicles and nanoparticles
  • Endothelium

Publications

  • Extracellular vesicle miR-93-5p cargo regulates glomerular endothelial cell damage in Alport syndrome. JCI Insight. 2026 Mar 23; 11(6).. View in PubMed
  • Kidney Endothelial Cell Biology in Health and Disease. J Am Soc Nephrol. 2024 05 01; 35(5):522-524.. View in PubMed
  • The spatially resolved transcriptome signatures of glomeruli in chronic kidney disease. JCI Insight. 2024 03 22; 9(6).. View in PubMed
  • C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy. JCI Insight. 2024 01 16; 9(4).. View in PubMed
  • Extracellular vesicles in kidney development and pediatric kidney diseases. Pediatr Nephrol. 2024 Jul; 39(7):1967-1975.. View in PubMed
  • Mitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation. Ann Surg. 2023 12 01; 278(6):e1313-e1326.. View in PubMed
  • Identification and Characterization of the Wilms Tumor Cancer Stem Cell. Adv Sci (Weinh). 2023 07; 10(20):e2206787.. View in PubMed
  • Intravital imaging reveals glomerular capillary distension and endothelial and immune cell activation early in Alport syndrome. JCI Insight. 2022 01 11; 7(1).. View in PubMed
  • Emerging Technologies to Study the Glomerular Filtration Barrier. Front Med (Lausanne). 2021; 8:772883.. View in PubMed
  • The spatially resolved transcriptional profile of acute T cell-mediated rejection in a kidney allograft. Kidney Int. 2022 01; 101(1):131-136.. View in PubMed