Siamak Daneshmand, MD

Professor of Urology (Clinical Scholar)

Director of Clinical Research

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Overview

BIOGRAPHY
Dr. Sia Daneshmand is currently Professor of Urology and Medicine (Oncology) with Clinical Scholar designation and serves as director of urologic oncology, as well as the urologic oncology (SUO) fellowship director at the University of Southern California (USC) in Los Angeles. His main clinical interests include bladder cancer, testicular cancer, and advanced kidney cancer. He is a leading authority in the management of complex germ cell tumors and nerve-sparing retroperitoneal lymph node dissection (RPLND) following chemotherapy for advanced testicular cancer and is one of the highest volume surgeons for this disease in the country. His main research interests focus on the use of pathways to improve peri-operative outcomes following radical cystectomy and post-chemo RPLND, use of serum and molecular markers and new technologies in diagnosis and management of bladder and testicular cancers, as well as functional outcomes following orthotopic urinary diversion. He serves on the AUA Guidelines panel for non-muscle invasive bladder cancer, as well as the AUA Guidelines panel for Testicular cancer. He currently serves as the chair of bladder section of the SUO Clinical Trials Consortium (SUO-CTC), is on the scientific steering committee of several bladder cancer clinical trials and has led over a dozen clinical trials in bladder cancer and a pivotal investigator initiated mutli-institutional trial in testicular cancer (SEMS). He is current secretary of the Western Section of the AUA. He is a member of Alpha Omega Alpha medical honor society and has been designated one of the “America’s Top Cancer Doctors” for the past 13 consecutive years. He has been a career leader in academic investigations in bladder cancer and germ cell tumors and was recently appointed as the chair of the SWOG local bladder committee. He has been a visiting professor at more than 25 institutions around the world. He has presented over 500 abstracts at scientific meetings and has authored or co-authored over 400 peer-reviewed articles, reviews, and book chapters.

Publications

Molecular Subtyping for Predicting Pathological Upstaging and Survival Outcomes in Clinically Organ-confined Bladder Cancer Patients Undergoing Radical Cystectomy Eur Urol Open Sci. 2025 Mar; 73:24-30. . View in PubMed
Bladder Preservation: An Overview of Novel Prospects and Limitations Int J Urol. 2025 Feb 27. . View in PubMed
Identification of genes associated with testicular germ cell tumor susceptibility through a transcriptome-wide association study Am J Hum Genet. 2025 Feb 18. . View in PubMed
Infigratinib Versus Placebo for Patients with High-risk Resected Urothelial Cancer Bearing an FGFR3 Genomic Alteration: Results from the PROOF302 Phase 3 Trial Eur Urol. 2025 Feb; 87(2):271-274. . View in PubMed
FGFR Inhibition in Urothelial Carcinoma Eur Urol. 2025 Feb; 87(2):110-122. . View in PubMed
Development of TAR-200: A novel targeted releasing system designed to provide sustained delivery of gemcitabine for patients with bladder cancer Urol Oncol. 2025 Jan 15. . View in PubMed
Eleven-Year Experience With Midline Extraperitoneal Retroperitoneal Lymph Node Dissection for Germ Cell Tumors J Urol. 2025 Jan; 213(1):60-70. . View in PubMed
Reply by Authors J Urol. 2025 Jan; 213(1):70. . View in PubMed
Residual cancer at radical cystectomy with or without neoadjuvant chemotherapy: a pathological stage-matched comparison BJU Int. 2025 Jan; 135(1):59-62. . View in PubMed
Technical Considerations to Minimize False-Positive Findings in Blue Light Cystoscopy for Nonmuscle-Invasive Bladder Cancer J Urol. 2025 Jan; 213(1):5-7. . View in PubMed
Primary retroperitoneal lymph node dissection in clinical stage 2a/b non-seminomatous germ cell tumour BJU Int. 2024 Dec 11. . View in PubMed
Novel Delivery Systems and Pharmacotherapeutic Approaches for the Treatment of Non-muscle-invasive Bladder Cancer Eur Urol Oncol. 2024 Dec; 7(6):1267-1279. . View in PubMed
Moving the Needle in Early-Stage Testicular Germ Cell Tumor Management: The MAGESTIC Trial J Urol. 2024 Dec; 212(6):907-909. . View in PubMed
Epidemiology and Risk Factors for Testicular Cancer: A Systematic Review Eur Urol. 2024 Nov 13. . View in PubMed
Driver mutations associated with signatures of platinum sensitivity in germ cell tumors NPJ Precis Oncol. 2024 Nov 02; 8(1):249. . View in PubMed
Clinical Significance of Tumor Location for Ureteroscopic Tumor Grading in Upper Tract Urothelial Carcinoma J Endourol. 2024 Nov; 38(11):1156-1163. . View in PubMed
Opioid prescription following radical orchiectomy associated with new persistent opioid useUrol Oncol. 2024 Nov; 42(11):375. e15-375. e21. . View in PubMed
Does radical cystectomy still have a role in BCG-unresponsive nonmuscle invasive bladder cancer? Curr Opin Urol. 2024 Nov 01; 34(6):489-494.. View in PubMed
A luminal non-coding RNA-based genomic classifier confirms favourable outcomes in patients with clinically organ-confined bladder cancer treated with radical cystectomy BJU Int. 2024 Nov 01. . View in PubMed
Disparities in Testicular Cancer: A Review of the Literature Cancers (Basel). 2024 Oct 10; 16(20). . View in PubMed
Standard or Extended Lymphadenectomy for Muscle-Invasive Bladder Cancer N Engl J Med. 2024 Oct 03; 391(13):1206-1216. . View in PubMed
Pathologic and survival outcomes following radical cystectomy for “progressive” and “de novo” muscle-invasive bladder cancer: A meta-analysis stratified by neoadjuvant chemotherapy statusUrol Oncol. 2024 Oct; 42(10):333. e1-333. e13. . View in PubMed
Surveillance of non-muscle-invasive bladder cancer with blue-light cystoscopy: a meta-analysis BJU Int. 2024 Oct; 134(4):526-533. . View in PubMed
Correlative Analysis of ATM, RB1, ERCC2, and FANCC Mutations and Pathologic Complete Response After Neoadjuvant Chemotherapy in Patients with Muscle-invasive Bladder Cancer: Results from the SWOG S1314 Trial Eur Urol. 2024 Oct; 86(4):297-300. . View in PubMed
Perioperative and extended outcomes of patients undergoing parastomal hernia repair following cystectomy and ileal conduit World J Urol. 2024 Aug 12; 42(1):482. . View in PubMed
Update on the Management of Low-stage Seminoma Urol Clin North Am. 2024 Aug; 51(3):377-385. . View in PubMed
A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy in Patients With Microhematuria: The Safe Testing of Risk for Asymptomatic Microhematuria Trial J Urol. 2024 Jul; 212(1):41-51. . View in PubMed
Reply by Authors J Urol. 2024 Jul; 212(1):50-51. . View in PubMed
Reply by Authors J Urol. 2024 Jun; 211(6):752-753. . View in PubMed
The effect of enhanced recovery after surgery on oncologic outcome following radical cystectomy for urothelial bladder carcinoma Surg Oncol. 2024 Jun; 54:102061. . View in PubMed
Reply by Authors J Urol. 2024 Jun; 211(6):751. . View in PubMed
Prophylactic Use of Biologic Mesh in Ileal Conduit (PUBMIC): A Randomized Clinical Trial J Urol. 2024 Jun; 211(6):743-753. . View in PubMed
Author Correction: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial Nat Med. 2024 Apr; 30(4):1211. . View in PubMed
Blood-based liquid biopsy: A promising noninvasive test in diagnosis, surveillance, and prognosis of patients with upper tract urothelial carcinomaUrol Oncol. 2024 04; 42(4):118. e9-118. e17. . View in PubMed
Interruptions in bladder cancer care during the COVID-19 public health emergencyUrol Oncol. 2024 04; 42(4):116. e17-116. e21. . View in PubMed
Racial Differences in the Detection Rate of Bladder Cancer Using Blue Light Cystoscopy: Insights from a Multicenter Registry Cancers (Basel). 2024 Mar 24; 16(7). . View in PubMed
Comparative cost-effectiveness of contemporary treatment strategies for stage IIA seminoma J Natl Cancer Inst. 2024 Mar 07; 116(3):468-475. . View in PubMed
Updated Overall Survival by Circulating Tumor DNA Status from the Phase 3 IMvigor010 Trial: Adjuvant Atezolizumab Versus Observation in Muscle-invasive Urothelial Carcinoma Eur Urol. 2024 Feb; 85(2):114-122. . View in PubMed
Association of Molecular Subtypes with Pathologic Response, PFS, and OS in a Phase II Study of COXEN with Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer Clin Cancer Res. 2024 01 17; 30(2):444-449. . View in PubMed
Diagnosis and Treatment of Early-Stage Testicular Cancer: AUA Guideline Amendment 2023 J Urol. 2024 01; 211(1):20-25. . View in PubMed
Survival of Patients with Chronic Kidney Disease Treated with Radical Cystectomy and Risk Factors of Glomerular Filtration Rate Loss Following Radical Cystectomy: Two Systematic Reviews and Meta-analyses of Interplay Between Radical Cystectomy and Renal Function Eur Urol Focus. 2024 Jan; 10(1):169-181. . View in PubMed
Risk Factors for Relapse in Nonseminomatous Testicular Cancer After Postchemotherapy Retroperitoneal Lymph Node Dissection With Viable Residual Cancer J Clin Oncol. 2023 Dec 01; 41(34):5296-5305. . View in PubMed
So, what now? Ann Oncol. 2023 12; 34(12):1077-1079.. View in PubMed
Reply to ARumyantsev et al. J Clin Oncol. 2023 11 20; 41(33):5203-5204. . View in PubMed
Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial Nat Med. 2023 Nov; 29(11):2825-2834. . View in PubMed
Cell-free DNA Methylation as a Predictive Biomarker of Response to Neoadjuvant Chemotherapy for Patients with Muscle-invasive Bladder Cancer in SWOG S1314 Eur Urol Oncol. 2023 10; 6(5):516-524. . View in PubMed
Metastatic Testicular Cancer Patterns and Predictors: A Contemporary Population-based SEER Analysis Urology. 2023 Oct; 180:182-189. . View in PubMed
The effect of cisplatin-based neoadjuvant chemotherapy on the renal function of patients undergoing radical cystectomy Can Urol Assoc J. 2023 Oct; 17(10):301-309. . View in PubMed
Long-term Outcomes from a Phase 2 Study of Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer (SWOG S1314; NCT02177695) Eur Urol. 2023 09; 84(3):341-347. . View in PubMed
Association between early postradical cystectomy kidney injury and perioperative outcome in enhanced recovery eraUrol Oncol. 2023 09; 41(9):389. e15-389. e20. . View in PubMed
Association Between Antibiotic Prophylaxis Before Cystectomy or Stent Removal and Infection Complications: A Systematic Review Eur Urol Focus. 2023 07; 9(4):631-636. . View in PubMed
Background and Update for ECOG-ACRIN EA8212: A Randomized Phase 3 Trial of Intravesical Bacillus Calmette-Guérin (BCG) Versus Intravesical Docetaxel and Gemcitabine Treatment in BCG-naïve High-grade Non-muscle-invasive Bladder Cancer (BRIDGE) Eur Urol Focus. 2023 07; 9(4):561-563. . View in PubMed
Radical cystectomy versus trimodality therapy for muscle-invasive bladder cancer: a multi-institutional propensity score matched and weighted analysis Lancet Oncol. 2023 06; 24(6):669-681. . View in PubMed
Surgery in Early Metastatic Seminoma: A Phase II Trial of Retroperitoneal Lymph Node Dissection for Testicular Seminoma With Limited Retroperitoneal Lymphadenopathy J Clin Oncol. 2023 06 01; 41(16):3009-3018. . View in PubMed
Plasma Micro-RNA 371 Expression in Early-Stage Germ Cell Tumors: Are We Ready to Move Toward Biology-Based Decision Making? J Clin Oncol. 2023 05 10; 41(14):2478-2482.. View in PubMed
Reply by Authors J Urol. 2023 05; 209(5):862. . View in PubMed
A Urine-based DNA Methylation Marker Test to Detect Upper Tract Urothelial Carcinoma: A Prospective Cohort Study J Urol. 2023 05; 209(5):854-862. . View in PubMed
Carboplatin Induction Chemotherapy in Clinically Lymph Node-positive Bladder Cancer Eur Urol Open Sci. 2023 May; 51:39-46. . View in PubMed
Perioperative mortality for radical cystectomy in the modern Era: experience from a tertiary referral center Int Braz J Urol. 2023 May-Jun; 49(3):351-358. . View in PubMed
Impact of Maximal Transurethral Resection on Pathological Outcomes at Cystectomy in a Large, Multi-institutional Cohort J Urol. 2023 05; 209(5):882-889. . View in PubMed
Urinary Analysis of FGFR3 and TERT Gene Mutations Enhances Performance of Cxbladder Tests and Improves Patient Risk Stratification J Urol. 2023 04; 209(4):762-772. . View in PubMed
Radical cystectomy and urinary diversion outcomes in patients with single vsdouble renal unit: A 2:1 matched-pair analysis. Urol Oncol. 2023 04; 41(4):207. e17-207. e22. . View in PubMed
Retroperitoneal Lymph Node Dissection Should Be a Standard-of-Care Treatment Option For Stage II Seminoma Eur Urol Open Sci. 2023 Mar; 49:67-68. . View in PubMed
Risk of residual cancer after complete response following first-line chemotherapy in men with metastatic non-seminomatous germ cell tumour and International Germ Cell Cancer Cooperative Group intermediate/poor prognosis: A multi-institutional retrospective cohort study Eur J Cancer. 2023 03; 182:144-154. . View in PubMed
Primary Retroperitoneal Lymph Node Dissection in Stage I and Low-volume Metastatic Germ Cell Tumors Eur Urol Focus. 2023 03; 9(2):248-250. . View in PubMed
Diagnostic Accuracy of Clinical Lymph Node Staging for Upper Tract Urothelial Cancer Patients: A Multicenter, Retrospective, Observational Study J Urol. 2023 03; 209(3):515-524. . View in PubMed
Comparing Oncological and Perioperative Outcomes of Open versus Laparoscopic versus Robotic Radical Nephroureterectomy for the Treatment of Upper Tract Urothelial Carcinoma: A Multicenter, Multinational, Propensity Score-Matched Analysis Cancers (Basel). 2023 Feb 23; 15(5). . View in PubMed
Is a restaging TURBT necessary in high-risk NMIBC if the initial TURBT was performed with blue light? Urol Oncol. 2023 02; 41(2):109.e9-109.e14.. View in PubMed
Late Complication of Orthotopic T-Pouch Ileal Neobladder Diversion Urology. 2023 02; 172:e1-e2. . View in PubMed
Development of a Pocket Nomogram to Predict Cancer and Disease Specific Survival After Radical Cystectomy For Bladder Cancer: The CRAB Nomogram Clin Genitourin Cancer. 2023 02; 21(1):108-114. . View in PubMed
Recurrence patterns in bladder cancer patients with no residual disease (pT0N0) at radical cystectomy: A 20-year experienceUrol Oncol. 2023 02; 41(2):107. e9-107. e14. . View in PubMed
Feminizing Adrenocortical Tumor with Multiple Recurrences: A Case Report Case Rep Oncol. 2023 Jan-Dec; 16(1):1033-1040. . View in PubMed
Commentary on Novitas LCD Bladder Cancer. 2023; 9(4):305-312. . View in PubMed
The Impact of Dose Reduction of Bacillus Calmette-Guerin on Oncological Outcomes and Toxicity in Non-Muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis Bladder Cancer. 2023; 9(3):227-236. . View in PubMed
Reply by Authors Urol Pract. 2022 11; 9(6):541. . View in PubMed
Multicenter evaluation of neoadjuvant and induction gemcitabine-carboplatin versus gemcitabine-cisplatin followed by radical cystectomy for muscle-invasive bladder cancer World J Urol. 2022 Nov; 40(11):2707-2715. . View in PubMed
5-Aminolevulinic acid-enhanced fluorescence-guided treatment of high-grade glioma using angled endoscopic blue light visualization: technical case series with preliminary follow-up J Neurosurg. 2022 Nov 01; 137(5):1378-1386. . View in PubMed
An Assessment Tool to Provide Targeted Feedback to Robotic Surgical Trainees: Development and Validation of the End-To-End Assessment of Suturing Expertise (EASE) Urol Pract. 2022 Nov; 9(6):532-539. . View in PubMed
Impact of Patient, Surgical, and Perioperative Factors on Discharge Disposition after Radical Cystectomy Cancers (Basel). 2022 Oct 27; 14(21). . View in PubMed
Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk Cancer Epidemiol Biomarkers Prev. 2022 09 02; 31(9):1769-1779. . View in PubMed
Machine Learning to Delineate Surgeon and Clinical Factors That Anticipate Positive Surgical Margins After Robot-Assisted Radical Prostatectomy J Endourol. 2022 09; 36(9):1192-1198. . View in PubMed
Risk factors and natural history of parastomal hernia after radical cystectomy and ileal conduit BJU Int. 2022 09; 130(3):381-388. . View in PubMed
Long-term renal function in patients with chronic kidney disease following radical cystectomy and orthotopic neobladder BJU Int. 2022 08; 130(2):200-207. . View in PubMed
Race reporting and disparities regarding clinical trials in bladder cancer: a systematic review Cancer Causes Control. 2022 Aug; 33(8):1071-1081. . View in PubMed
Safety of repeat blue light cystoscopy with hexaminolevulinate (HAL) in the management of bladder cancer: Results from a phase III, comparative, multi-center studyUrol Oncol. 2022 08; 40(8):382. e1-382. e6. . View in PubMed
Chronic kidney disease and radical cystectomy for bladder cancer: perioperative and oncologic outcomes in 1,214 patientsUrol Oncol. 2022 08; 40(8):381. e9-381. e16. . View in PubMed
Targeting FGFR3 alterations with adjuvant infigratinib in invasive urothelial carcinoma: the phase III PROOF 302 trial Future Oncol. 2022 Jul; 18(21):2599-2614. . View in PubMed
Role of blue-light cystoscopy in detecting invasive bladder tumours: data from a multi-institutional registry BJU Int. 2022 07; 130(1):62-67. . View in PubMed
Re: Detection Rate of CIS During TURBT Following Shift From PDD to NBI in a Single University Hospital Urology. 2022 07; 165:e47. . View in PubMed
The safety, tolerability, and efficacy of a neoadjuvant gemcitabine intravesical drug delivery system (TAR-200) in muscle-invasive bladder cancer patients: a phase I trialUrol Oncol. 2022 07; 40(7):344. e1-344. e9. . View in PubMed
Pediatric genitourinary tumors: Distribution, demographics, and outcomes Pediatr Investig. 2022 Jun; 6(2):85-92. . View in PubMed
Association between use of ERAS protocols and complications after radical cystectomy World J Urol. 2022 Jun; 40(6):1311-1316. . View in PubMed
Critical analysis of quality of life and cost-effectiveness of enhanced recovery after surgery (ERAS) for patient’s undergoing urologic oncology surgery: a systematic review World J Urol. 2022 Jun; 40(6):1325-1342. . View in PubMed
Pentafecta for Radical Nephroureterectomy in Patients with High-Risk Upper Tract Urothelial Carcinoma: A Proposal for Standardization of Quality Care Metrics Cancers (Basel). 2022 Mar 31; 14(7). . View in PubMed
Utility of Blue Light Cystoscopy for Post-bacillus Calmette-Guérin Bladder Cancer Recurrence Detection: Implications for Clinical Trial Recruitment and Study Comparisons J Urol. 2022 Mar; 207(3):534-540. . View in PubMed
Reply by Authors J Urol. 2022 02; 207(2):313. . View in PubMed
Infigratinib in Early-Line and Salvage Therapy for FGFR3-Altered Metastatic Urothelial Carcinoma Clin Genitourin Cancer. 2022 02; 20(1):35-42. . View in PubMed
Management Trends and Outcomes of Patients Undergoing Radical Cystectomy for Urothelial Carcinoma of the Bladder: Evolution of the University of Southern California Experience over 3,347 Cases J Urol. 2022 Feb; 207(2):302-313. . View in PubMed
Clinical stage II seminoma: management options World J Urol. 2022 Feb; 40(2):343-348. . View in PubMed
Bladder Recurrence Following Diagnostic Ureteroscopy in Patients Undergoing Nephroureterectomy for Upper Tract Urothelial Cancer: Is Ureteral Access Sheath Protective? Urology. 2022 02; 160:142-146.. View in PubMed
Identifying the Optimal Number of Neoadjuvant Chemotherapy Cycles in Patients with Muscle Invasive Bladder Cancer J Urol. 2022 01; 207(1):70-76. . View in PubMed
Macro and microeconomics of blue light cystoscopy with CYSVIEW® in non-muscle invasive bladder cancerUrol Oncol. 2022 01; 40(1):10. e7-10. e12. . View in PubMed
Clinical Utility of Rigid Blue Light Cystoscopy: Results from a Post Procedure User Survey in a Prospective Multicenter Registry Urol Pract. 2022 01; 9(1):94-100. . View in PubMed
Safety and feasibility of urological procedures in Jehovah’s Witness patients Int J Urol. 2022 Jan; 29(1):83-88. . View in PubMed
An emerging role for immuno-nutrition in patients undergoing radical cystectomy Nat Rev Urol. 2022 01; 19(1):1-2. . View in PubMed
Intricacies of retroperitoneal lymph node dissection for testis cancer Curr Opin Urol. 2022 Jan 01; 32(1):24-30. . View in PubMed
Association of age with response to preoperative chemotherapy in patients with muscle-invasive bladder cancer World J Urol. 2021 Dec; 39(12):4345-4354. . View in PubMed
The Diagnostic Performance of Cxbladder Resolve, Alone and in Combination with Other Cxbladder Tests, in the Identification and Priority Evaluation of Patients at Risk for Urothelial Carcinoma J Urol. 2021 12; 206(6):1380-1389. . View in PubMed
Patient Reported Sexual Function Outcomes in Male Patients Following Open Radical Cystoprostatectomy and Urinary Diversion Urology. 2021 11; 157:161-167. . View in PubMed
Evaluation of Bowel Function Following Radical Cystectomy and Urinary Diversion Using Two Validated Questionnaires: What Are the Effects on Quality of Life? Urology. 2021 10; 156:279-284.. View in PubMed
Enhanced recovery after cystectomy in patients with preoperative narcotic use Can Urol Assoc J. 2021 Oct; 15(10):E563-E568. . View in PubMed
Vena Cava Tumor Thrombus Associated With Renal Angiomyolipoma in a Jehovah’s Witness Patient Urology. 2021 Oct; 156:e86-e87. . View in PubMed
Validation of the COBRA nomogram for the prediction of cancer specific survival in patients treated with radical cystectomy for bladder cancer: An international wide cohort study Eur J Surg Oncol. 2021 10; 47(10):2646-2650. . View in PubMed
Editorial by Bendu KKonneh, John T. Lafin and Aditya Bagrodia on pp. 341-342 of this issue: MicroRNA-371a-3p as a blood-based biomarker in testis cancer. Asian J Urol. 2021 Oct; 8(4):400-406. . View in PubMed
Reply by Authors Urol Pract. 2021 Sep; 8(5):604. . View in PubMed
Predictors of need for catheterisation and urinary retention after radical cystectomy and orthotopic neobladder in male patients BJU Int. 2021 09; 128(3):304-310. . View in PubMed
Impact of Non-guideline-directed Care on Quality of Life in Testicular Cancer Survivors Eur Urol Focus. 2021 Sep; 7(5):1137-1142. . View in PubMed
Perioperative outcomes of goal-directed versus conventional fluid therapy in radical cystectomy with enhanced recovery protocol Int Urol Nephrol. 2021 Sep; 53(9):1827-1833. . View in PubMed
Development and validation of an objective scoring tool to evaluate surgical dissection: Dissection Assessment for Robotic Technique (DART) Urol Pract. 2021 Sep; 8(5):596-604. . View in PubMed
Performance of Narrow Band Imaging (NBI) and Photodynamic Diagnosis (PDD) Fluorescence Imaging Compared to White Light Cystoscopy (WLC) in Detecting Non-Muscle Invasive Bladder Cancer: A Systematic Review and Lesion-Level Diagnostic Meta-Analysis Cancers (Basel). 2021 Aug 30; 13(17). . View in PubMed
A Massive Penile Tumor Urology. 2021 08; 154:e5-e6. . View in PubMed
Role of Ki-67, MRE11, and PD-L1 as Predictive Biomarkers for Recurrence Pattern in Muscle-invasive Bladder Cancer Anticancer Res. 2021 Aug; 41(8):3851-3857. . View in PubMed
ctDNA guiding adjuvant immunotherapy in urothelial carcinoma Nature. 2021 07; 595(7867):432-437. . View in PubMed
Neoadjuvant chemotherapy plus radical cystectomy versus radical cystectomy alone in clinical T2 bladder cancer without hydronephrosis BJU Int. 2021 07; 128(1):79-87. . View in PubMed
Diagnosis and Staging of Bladder Cancer Hematol Oncol Clin North Am. 2021 06; 35(3):531-541. . View in PubMed
Enhanced Endoscopy with IMAGE1 S CHROMA Improves Detection of Nonmuscle Invasive Bladder Cancer During Transurethral Resection J Endourol. 2021 05; 35(5):647-651. . View in PubMed
A Randomized Phase II Study of Coexpression Extrapolation (COXEN) with Neoadjuvant Chemotherapy for Bladder Cancer (SWOG S1314; NCT02177695) Clin Cancer Res. 2021 05 01; 27(9):2435-2441. . View in PubMed
Comparative effectiveness of neoadjuvant chemotherapy in bladder and upper urinary tract urothelial carcinoma BJU Int. 2021 05; 127(5):528-537. . View in PubMed
Disparities in male versus female oncologic outcomes following bladder preservation: A population-based cohort study Cancer Med. 2021 05; 10(9):3004-3012. . View in PubMed
Stoma complications and quality of life in patients with Indiana pouch versus appendico/neo-appendico-umbilicostomy urinary diversions World J Urol. 2021 May; 39(5):1521-1529. . View in PubMed
Clinical evaluation of Bladder CARE, a new epigenetic test for bladder cancer detection in urine samples Clin Epigenetics. 2021 04 21; 13(1):84. . View in PubMed
Adjuvant atezolizumab versus observation in muscle-invasive urothelial carcinoma (IMvigor010): a multicentre, open-label, randomised, phase 3 trial Lancet Oncol. 2021 04; 22(4):525-537. . View in PubMed
Genetic Differences Between Bladder and Upper Urinary Tract Carcinoma: Implications for Therapy Eur Urol Oncol. 2021 04; 4(2):170-179. . View in PubMed
Best Practices to Optimise Quality and Outcomes of Transurethral Resection of Bladder Tumours Eur Urol Oncol. 2021 02; 4(1):12-19. . View in PubMed
Feasibility and Outcomes of Orthotopic Ileal Neobladder Reconstruction Following Pelvic Irradiation Urology. 2021 02; 148:198-202. . View in PubMed
Preoperative chemotherapy in clinically node positive muscle invasive bladder cancer: Radiologic variables can predict responseUrol Oncol. 2021 02; 39(2):133. e1-133. e8. . View in PubMed
Discrepancies in the Recommended Management of Adrenal Incidentalomas by Various Guidelines J Urol. 2021 Jan; 205(1):52-59. . View in PubMed
A Novel DNA Methylation Signature as an Independent Prognostic Factor in Muscle-Invasive Bladder Cancer Front Oncol. 2021; 11:614927. . View in PubMed
Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and Active Germ Cell Malignancy Components in Malignant Germ Cell Tumors Eur Urol. 2021 01; 79(1):16-19. . View in PubMed
Prospective evaluation of blue-light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer BJU Int. 2021 01; 127(1):108-113. . View in PubMed
Multiparametric cystoscopy: is the future here yet? Transl Androl Urol. 2021 Jan; 10(1):1-6.. View in PubMed
Hyperphosphatemia Secondary to the Selective Fibroblast Growth Factor Receptor 1-3 Inhibitor Infigratinib (BGJ398) Is Associated with Antitumor Efficacy in Fibroblast Growth Factor Receptor 3-altered Advanced/Metastatic Urothelial Carcinoma Eur Urol. 2020 12; 78(6):916-924. . View in PubMed
Internal audit of an enhanced recovery after surgery protocol for radical cystectomy World J Urol. 2020 Dec; 38(12):3131-3137. . View in PubMed
Quality reporting in postchemotherapy retroperitoneal lymph node dissection Cancer. 2020 11 15; 126(22):4825. . View in PubMed
Reply to Gianluca Giannarini, Vincenzo Ficarra, and Claudio Valotto’s Letter to the Editor re: Stephen BWilliams, Marcus G. K. Cumberbatch, Ashish M. Kamat, et al. Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis. Eur Urol. In press. https://doi. org/10. 1016/j. eururo. 2020. 06. 039. Eur Urol. 2020 11; 78(5):e190-e191. . View in PubMed
Optimizing Outcomes in Urological Surgery: Postoperative Care Urol Pract. 2020 Nov; 7(6):521-529. . View in PubMed
Reporting Radical Cystectomy Outcomes Following Implementation of Enhanced Recovery After Surgery Protocols: A Systematic Review and Individual Patient Data Meta-analysis Eur Urol. 2020 11; 78(5):719-730. . View in PubMed
Perioperative complications and oncological outcomes following radical cystectomy among different racial groups: A long-term, single-center study Can Urol Assoc J. 2020 Oct; 14(10):E493-E498. . View in PubMed
Variability in adherence to guidelines based management of nonmuscle invasive bladder cancer among Society of Urologic Oncology (SUO) membersUrol Oncol. 2020 10; 38(10):796. e1-796. e6. . View in PubMed
Perioperative Outcome of Suprarenal Resection of Vena Cava Without Reconstruction in Urologic Malignancies: A Case Series and Review of the Literature Urology. 2020 08; 142:146-154. . View in PubMed
Chemoradiation for Management of Locally Recurrent or Residual Bladder Cancer: A Case Series and Review of the Literature Clin Genitourin Cancer. 2020 08; 18(4):e473-e477. . View in PubMed
AUTHOR REPLY Urology. 2020 08; 142:154. . View in PubMed
Occult Nodal Metastases in Patients Down-Staged to Nonmuscle Invasive Disease Following Neoadjuvant Chemotherapy Urology. 2020 08; 142:155-160. . View in PubMed
Neoadjuvant Chemotherapy in Variant Histology Bladder Cancer: Current Evidence Eur Urol Focus. 2020 07 15; 6(4):639-641. . View in PubMed
Bladder Cancer: Advances and Innovations Eur Urol Focus. 2020 07 15; 6(4):613-614. . View in PubMed
Impact of sex on response to neoadjuvant chemotherapy in patients with bladder cancerUrol Oncol. 2020 07; 38(7):639. e1-639. e9. . View in PubMed
Zero, Some Chemotherapy Game in Early-Stage Germ Cell Tumors J Clin Oncol. 2020 07 01; 38(19):2214-2215. . View in PubMed
Transurethral Resection of Bladder Tumour: The Neglected Procedure in the Technology Race in Bladder Cancer Eur Urol. 2020 06; 77(6):669-670. . View in PubMed
Infigratinib in upper tract urothelial carcinoma versus urothelial carcinoma of the bladder and its association with comprehensive genomic profiling and/or cell-free DNA results Cancer. 2020 06 01; 126(11):2597-2606. . View in PubMed
EDITORIAL COMMENT Urology. 2020 06; 140:120-121. . View in PubMed
National Practice Patterns and Overall Survival After Adjuvant Radiotherapy Following Radical Cystectomy for Urothelial Bladder Cancer in the USA, 2004-2013 Eur Urol Oncol. 2020 06; 3(3):343-350. . View in PubMed
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Surveillance guidelines based on recurrence patterns after radical cystectomy for bladder cancer: the Canadian Bladder Cancer Network experience BJU Int. 2012 Nov; 110(9):1324. . View in PubMed
Contemporary management of postchemotherapy testis cancer Eur Urol. 2012 Nov; 62(5):867-76. . View in PubMed
Critical evaluation of the American Joint Committee on Cancer TNM nodal staging system in patients with lymph node-positive disease after radical cystectomy Eur Urol. 2012 Oct; 62(4):671-6. . View in PubMed
Stage-specific impact of tumor location on oncologic outcomes in patients with upper and lower tract urothelial carcinoma following radical surgery Eur Urol. 2012 Oct; 62(4):677-84. . View in PubMed
Midline extraperitoneal approach for retroperitoneal lymph node dissection for testicular germ cell tumor Urology. 2012 Oct; 80(4):941-5. . View in PubMed
Editorial comment Urology. 2012 Sep; 80(3):639; author reply 639-40. . View in PubMed
A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer Eur Urol. 2012 Sep; 62(3):523-33. . View in PubMed
Adjuvant surgery in testicular cancer patients undergoing postchemotherapy retroperitoneal lymph node dissection Ann Surg Oncol. 2012 Jul; 19(7):2388-93. . View in PubMed
The value of extended transurethral resection of bladder tumour (TURBT) in the treatment of bladder cancer BJU Int. 2012 Jul; 110(2 Pt 2):E80. . View in PubMed
Long-term outcomes of open radical retropubic prostatectomy for clinically localized prostate cancer in the prostate-specific antigen era Urology. 2012 Mar; 79(3):626-31. . View in PubMed
Factors influencing post-recurrence survival in bladder cancer following radical cystectomy BJU Int. 2012 Mar; 109(6):846-54. . View in PubMed
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Clinical nodal staging scores for bladder cancer: a proposal for preoperative risk assessment Eur Urol. 2012 Feb; 61(2):237-42. . View in PubMed
Colocalycostomy for repair of ureterojejunal fistula Urology. 2012 Feb; 79(2):e12-4. . View in PubMed
Renal cell carcinoma with inferior vena cava tumor thrombus and metastatic caval wall invasion Urology. 2012 Feb; 79(2):e6-8. . View in PubMed
Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics Front Endocrinol (Lausanne). 2012; 3:182. . View in PubMed
Chemoresponsive liver hemangioma in a patient with a metastatic germ cell tumor J Clin Oncol. 2011 Dec 10; 29(35):e842-4. . View in PubMed
The management of subcentimeter residual mass in NSGCT: pcRPLND vsobservation. Urol Oncol. 2011 Nov-Dec; 29(6):842-7. . View in PubMed
Lymph node dissection technique is more important than lymph node count in identifying nodal metastases in radical cystectomy patients: a comparative mapping study Eur Urol. 2011 Nov; 60(5):946-52. . View in PubMed
Super extended versus extended pelvic lymph node dissection in patients undergoing radical cystectomy for bladder cancer: a comparative study J Urol. 2011 Oct; 186(4):1261-8. . View in PubMed
Management of residual mass in nonseminomatous germ cell tumors following chemotherapy Ther Adv Urol. 2011 Aug; 3(4):163-71. . View in PubMed
Androgen-producing testicular germ cell tumors J Clin Oncol. 2011 Jul 20; 29(21):e634-5. . View in PubMed
Improving selection of appropriate urinary diversion following radical cystectomy for bladder cancer Expert Rev Anticancer Ther. 2011 Jun; 11(6):941-8. . View in PubMed
Evaluation and Preservation of Fertility in Patients with Testicular Cancer J Adolesc Young Adult Oncol. 2011 Mar; 1(1):25-9. . View in PubMed
Editorial comment Urology. 2010 Oct; 76(4):1001. . View in PubMed
Distinctive morphology of renal cell carcinomas in tuberous sclerosis Int J Surg Pathol. 2010 Oct; 18(5):409-18. . View in PubMed
Factors influencing the choice of urinary diversion in patients undergoing radical cystectomy BJU Int. 2010 Sep; 106(5):654-7. . View in PubMed
Management of disseminated nonseminomatous germ cell tumors with risk-based chemotherapy followed by response-guided postchemotherapy surgery J Clin Oncol. 2010 Feb 01; 28(4):537-42. . View in PubMed
Resection of the inferior vena cava without reconstruction for urologic malignancies Urology. 2009 Dec; 74(6):1257-62. . View in PubMed
Open partial nephrectomy for pediatric renovascular hypertension ScientificWorldJournal. 2009 Apr 28; 9:287-90. . View in PubMed
Re: Appendiceal substitution following right proximal ureter injury Int Braz J Urol. 2009 Jan-Feb; 35(1):90-1. . View in PubMed
Venous resection in urological surgery J Urol. 2008 Dec; 180(6):2338-42; discussion 2342. . View in PubMed
Words of wisdomRe: use of androgen deprivation therapy for metastatic prostate cancer in older men. Eur Urol. 2008 Nov; 54(5):1201-2. . View in PubMed
Application of the Yang-Monti channel in adult continent cutaneous urinary diversion Urology. 2008 Oct; 72(4):828-31. . View in PubMed
Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival Hum Pathol. 2007 Oct; 38(10):1547-52. . View in PubMed
Re: Prediagnosis prostate specific antigen velocity is associated with risk of prostate cancer progression following brachytherapy and external beam radiation therapyS. E. Eggener, K. A. Roehl, O. Yossepowitch and W. J. Catalona, J Urol 2006; 176: 1399-1403. J Urol. 2007 Jun; 177(6):2396; author reply 2396-7. . View in PubMed
Bilateral segmental testicular infarction ScientificWorldJournal. 2007 Feb 19; 7:779-83. . View in PubMed
Evolving treatment paradigms for locally advanced and metastatic prostate cancer Expert Rev Anticancer Ther. 2006 Nov; 6(11):1639-51. . View in PubMed
Management of difficult germ-cell tumors Oncology (Williston Park). 2006 Nov; 20(12):1565-701575; discussion 1575-6. . View in PubMed
Prognostic significance of neuroendocrine expression in lymph node-positive prostate cancer Urology. 2006 Jun; 67(6):1247-52. . View in PubMed
A critical analysis of perioperative mortality from radical cystectomy J Urol. 2006 Mar; 175(3 Pt 1):886-9; discussion 889-90. . View in PubMed
Intraoperative renal cell carcinoma tumor embolization to the right atrium: incidental diagnosis by transesophageal echocardiography Anesth Analg. 2006 Feb; 102(2):378-9. . View in PubMed
Adrenal myelolipoma: diagnosis and management Urol J. 2006; 3(2):71-4. . View in PubMed
Radical cystectomy for primary neuroendocrine tumors of the bladder: the university of southern california experience J Urol. 2005 Jul; 174(1):93-6. . View in PubMed
Prognostic significance of lymphovascular invasion of bladder cancer treated with radical cystectomy J Urol. 2005 Jul; 174(1):103-6. . View in PubMed
Current clinical trials in renal cell carcinoma Urol Oncol. 2005 Jul-Aug; 23(4):289-92. . View in PubMed
EphB4 expression and biological significance in prostate cancer Cancer Res. 2005 Jun 01; 65(11):4623-32. . View in PubMed
Ethnic differences in neuroendocrine cell expression in normal human prostatic tissue Urology. 2005 May; 65(5):1008-12. . View in PubMed
Prognosis of patients with lymph node positive prostate cancer following radical prostatectomy: long-term results J Urol. 2004 Dec; 172(6 Pt 1):2252-5. . View in PubMed
The importance of an extended lymphadenectomy in the management of high-grade invasive bladder cancer Expert Rev Anticancer Ther. 2004 Dec; 4(6):1007-16. . View in PubMed
Angiomyolipoma of the kidney: expanding disease spectrum demonstrated by 3 cases Appl Immunohistochem Mol Morphol. 2004 Sep; 12(3):277-83. . View in PubMed
New molecular markers for bladder cancer detection Curr Opin Urol. 2004 Sep; 14(5):259-64. . View in PubMed
Renal angiomyolipoma with liposarcomatous transformation: a case report and review of the literature Urol Oncol. 2004 Sep-Oct; 22(5):425-7. . View in PubMed
Prognosis of seminal vesicle involvement by transitional cell carcinoma of the bladder J Urol. 2004 Jul; 172(1):81-4. . View in PubMed
Adenomatous polyp of the verumontanum causing bladder outlet obstruction ScientificWorldJournal. 2004 Jun 07; 4 Suppl 1:89-91. . View in PubMed
Primary renal carcinoid tumor ScientificWorldJournal. 2004 Jun 03; 4:378-80. . View in PubMed
Sonography of spermatic cord leiomyoma: case report and review of the literature J Ultrasound Med. 2004 Apr; 23(4):569-71. . View in PubMed
Continent right colon reservoir using a cutaneous appendicostomy Urology. 2004 Mar; 63(3):577-80; discussion 580-1. . View in PubMed
Microscopic and gross extravesical extension in pathological staging of bladder cancer J Urol. 2004 Feb; 171(2 Pt 1):640-5. . View in PubMed
Benign retroperitoneal schwannoma: a case series and review of the literature Urology. 2003 Dec; 62(6):993-7. . View in PubMed
Natural history of surgically treated bladder carcinoma with extravesical tumor extension Cancer. 2003 Sep 01; 98(5):955-61. . View in PubMed
Endoscopic management of upper urinary tract transitional cell carcinoma: long-term experience Cancer. 2003 Jul 01; 98(1):55-60. . View in PubMed
Molecular prognostication in bladder cancer–a current perspective Eur J Cancer. 2003 Jul; 39(11):1501-10. . View in PubMed
Colourachal fistula in an adult presenting with feculent umbilical drainage J Urol. 2003 Jul; 170(1):184. . View in PubMed
Sarcomatoid renal cell carcinoma with massive osteosarcomatous differentiation: an unusual image in clinical urology Urology. 2003 May; 61(5):1031-2. . View in PubMed
Puboprostatic sling repair for treatment of urethral incompetence in adult neurogenic incontinence J Urol. 2003 Jan; 169(1):199-202. . View in PubMed
Endoscopic management of renal hemangioma J Urol. 2002 Feb; 167(2 Pt 1):488-9. . View in PubMed
Review of techniques to remove a Foley catheter when the balloon does not deflate Urology. 2002 Jan; 59(1):127-9. . View in PubMed
Dramatic declines in implantation and pregnancy rates in patients who undergo repeated cycles of in vitro fertilization with blastocyst transfer after one or more failed attempts Fertil Steril. 2001 Sep; 76(3):538-42. . View in PubMed
Infertile women of advanced reproductive ageVariability of day 3 FSH and E2 levels. J Reprod Med. 1998 Dec; 43(12):1023-6. . View in PubMed

Siamak Daneshmand, MD

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