Sita Reddy, PhD

Associate Professor of Cancer Biology

Co-Director of the Molecular Medicine PhD Program

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Research Funding

Small molecule therapeutics for myotonic dystrophy type 1
NIH · R01NS126219 · Jan 15, 2023 – Dec 31, 2027 · Role: Co-Principal Investigator
Mechanism of Small Molecule Mediated Rescue of Mytonic Dystrophy
NIH · R01NS080547 · Apr 1, 2013 – Mar 31, 2019 · Role: Principal Investigator
Identification of Therapeutic Small Molecules for Myotonic Dystrophy Type 1
NIH · R21NS077722 · Sep 30, 2011 – Aug 31, 2014 · Role: Principal Investigator
High Throughput Screen for Myotonic Dystrophy Type 1
NIH · R03MH095544 · Jul 22, 2011 – Jun 30, 2012 · Role: Principal Investigator
Biochemical analyses of muscleblind complexes in myotonic dystrophy
NIH · R01NS060839 · Feb 1, 2007 – Nov 30, 2014 · Role: Principal Investigator
Molecular Mechanisms Underlying DM1
NIH · R01NS050861 · Jul 8, 2006 – Jun 30, 2012 · Role: Principal Investigator
MOLECULAR MECHANISMS WHEREBY CTG EXPANSION RESULTS IN DM
NIH · R01NS041116 · Sep 1, 2000 – Aug 31, 2007 · Role: Principal Investigator

Mbnl1 and Mbnl2 regulate brain structural integrity in mice. Commun Biol. 2021 11 30; 4(1):1342.. View in PubMed
RNA splicing is responsive to MBNL1 dose. PLoS One. 2012; 7(11):e48825.. View in PubMed
Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins. Cell. 2012 Aug 17; 150(4):710-24.. View in PubMed
A filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction. Aging (Albany NY). 2012 Aug; 4(8):567-77.. View in PubMed
Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex. J Biol Chem. 2011 Nov 04; 286(44):38427-38438.. View in PubMed
Lamin A, farnesylation and aging. Exp Cell Res. 2012 Jan 01; 318(1):1-7.. View in PubMed
RNA steady-state defects in myotonic dystrophy are linked to nuclear exclusion of SHARP. EMBO Rep. 2011 Jul 01; 12(7):735-42.. View in PubMed
Cell cycle-regulated association between the Werner syndrome protein and its molecular partners. Cell Cycle. 2011 Jun 15; 10(12):2038-40.. View in PubMed
Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells. Aging (Albany NY). 2011 Apr; 3(4):395-406.. View in PubMed
Accumulation of distinct prelamin A variants in human diploid fibroblasts differentially affects cell homeostasis. Exp Cell Res. 2011 Feb 01; 317(3):319-29.. View in PubMed