Sonia Pawluczyk, MD

Clinical Assistant Professor of Psychiatry & the Behavioral Sciences (Part-Time)

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Overview

Dr. Pawluczyk was born in Buenos Aires, Argentina. After receiving her MD diploma at the Medical School of the University of Buenos Aires, she completed the “Curso Superior de Psiquiatria” at Hospital Borda. She moved to Los Angeles and entered the residency training in Psychiatry at LAC+USC. She did a fellowship in Psychiatry and the Law and in Geriatric Psychiatry. She then joined the Department of Psychiatry and has been part of the Geriatric Studies Center since 1991. Dr. Pawluczyk practices at the Memory and Aging Center at USC and she is also a consultant at Rancho Los Amigos Hospital. Dr. Pawluczyk is fluent in Spanish.

Publications

  • A Machine Learning Approach to Predict Cognitive Decline in Alzheimer Disease Clinical Trials. Neurology. 2025 Apr 22; 104(8):e213490.. View in PubMed
  • Deep learning to quantify the pace of brain aging in relation to neurocognitive changes. Proc Natl Acad Sci U S A. 2025 Mar 11; 122(10):e2413442122.. View in PubMed
  • Learning-based inference of longitudinal image changes: Applications in embryo development, wound healing, and aging brain. Proc Natl Acad Sci U S A. 2025 Feb 25; 122(8):e2411492122.. View in PubMed
  • Dynamic proportional loss of functional connectivity revealed change of left superior frontal gyrus in subjective cognitive decline: an explanatory study based on Chinese and Western cohorts. Geroscience. 2025 08; 47(4):5619-5634.. View in PubMed
  • MRI Signature of α-Synuclein Pathology in Asymptomatic Stages and a Memory Clinic Population. JAMA Neurol. 2024 Oct 01; 81(10):1051-1059.. View in PubMed
  • Safety, tolerability, and pharmacokinetics of allopregnanolone as a regenerative therapeutic for Alzheimer’s disease: A single and multiple ascending dose phase 1b/2a clinical trial. Alzheimers Dement (N Y). 2020; 6(1):e12107.. View in PubMed
  • Safety and feasibility of estrogen receptor-β targeted phytoSERM formulation for menopausal symptoms: phase 1b/2a randomized clinical trial. Menopause. 2019 08; 26(8):874-884.. View in PubMed
  • Evaluation of Medicare Claims Data as a Tool to Identify Dementia. J Alzheimers Dis. 2019; 67(2):769-778.. View in PubMed
  • Heterogeneity of Treatment Response to Citalopram for Patients With Alzheimer’s Disease With Aggression or Agitation: The CitAD Randomized Clinical Trial. Am J Psychiatry. 2016 May 01; 173(5):465-72.. View in PubMed
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90.. View in PubMed