Stacey Deleria Finley, PhD

Professor of Biomedical Engineering and Quantitative and Computational Biology

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Overview

Dr. Stacey Finley joined the Biomedical Engineering Department at USC in 2013. Dr. Finley received her Bachelor’s degree in Chemical Engineering from Florida A & M University in 2004. She pursued graduate studies in Chemical Engineering and received her Ph.D. in 2009 from Northwestern University. While at Northwestern, Dr. Finley was a recipient of the NSF Graduate Research Fellowship and a participant in the NIH Biotechnology Predoctoral Training Program. Following her graduate work, Dr. Finley was a postdoctoral research fellow at Johns Hopkins University School of Medicine. She was awarded postdoctoral fellowships from the NIH National Research Service Award (NRSA) and the UNCF/Merck Science Initiative. She is a member of American Association of Cancer Research (AACR), American Institute of Chemical Engineers (AIChE), Biomedical Engineering Society (BMES), International Society for Computational Biology (ISCB), and the Society of Mathematical Biology (SMB).

Awards

  • Keystone Symposia Fellow, 2016
  • Diverse: Issues in Higher Education: Emerging Scholar Award, 2015
  • National Academy of Engineering: Frontiers in Engineering Education, 2014
  • University of Southern California: WiSE Gabilan Assistant Professorship, 2013
  • Journal Biotechnology and Bioengineering: Elmer Gaden Jr. Award, 2010
  • National Institutes of Health: Ruth L. Kirschstein NRSA Postdoctoral Fellowship, 2010
  • UNCF/Merck Science Initiative: Postdoctoral Science Research Fellowship, 2010
  • National Science Foundation: Graduate Research Fellowship, 2006

Research Funding

  • Exploring the dynamic tumor-immune ecosystem of breast cancer in heterogeneous tumor microenvironments
    NIH · U01CA293859 · Aug 4, 2025 – Jul 31, 2030 · Role: Principal Investigator
  • Modeling based design of chimeric antigen receptors for Natural Killer cell-based immunotherapy
    NIH · U01CA275808 · Sep 9, 2022 – Aug 31, 2027 · Role: Principal Investigator
  • Multiscale systems biology modeling to exploit tumor-stromal metabolic crosstalk in colorectal cancer
    NIH · U01CA232137 · Sep 13, 2018 – Aug 31, 2023 · Role: Principal Investigator
  • Predictive model of pro- and anti-angiogenic factors involved in breast cancer
    NIH · F32CA154213 · Sep 15, 2010 – Feb 14, 2013 · Role: Principal Investigator

Publications

  • Systems biology during 20 years of PLoS Computational Biology. PLoS Comput Biol. 2026 Jul; 22(7):e1014465.. View in PubMed
  • A multiscale, Bayesian inference approach to augment mechanistic models of cell signaling with machine-learning predictions of binding affinity. PLoS Comput Biol. 2026 06; 22(6):e1014321.. View in PubMed
  • Cancer-associated fibroblasts drive metabolic heterogeneity in colorectal cancer cells: predictions from metabolic modeling. NPJ Syst Biol Appl. 2026 Mar 04; 12(1).. View in PubMed
  • Clinical and molecular characterization of AXL in colorectal cancer, CALGB (Alliance)/SWOG 80405 and real-world data. J Immunother Cancer. 2025 Dec 21; 13(12).. View in PubMed
  • Multiscale Probabilistic Modeling: A Bayesian Approach to Augment Mechanistic Models of Cell Signaling with Machine-Learning Predictions of Binding Affinity. bioRxiv. 2025 Jul 09.. View in PubMed
  • Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer. NPJ Syst Biol Appl. 2025 Jan 28; 11(1):12.. View in PubMed
  • Jewel Plummer Cobb: A trailblazing life of impact. Curr Biol. 2024 12 16; 34(24):R1205-R1211.. View in PubMed
  • Merging Metabolic Modeling and Imaging for Screening Therapeutic Targets in Colorectal Cancer. bioRxiv. 2024 Dec 05.. View in PubMed
  • Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. Cell Mol Immunol. 2024 12; 21(12):1459-1473.. View in PubMed
  • Integrating mechanism-based T cell phenotypes into a model of tumor-immune cell interactions. APL Bioeng. 2024 Sep; 8(3):036111.. View in PubMed