Steven Gazal

Assistant Professor of Population and Public Health Sciences, Clinical Pharmacy and Quantitative and Computational Biology

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Overview

Steven Gazal is an assistant professor at the Center for Genetic Epidemiology, in the Department of Population and Public Health Sciences at USC Keck School of Medicine. His research focuses on developing and applying statistical methods to understand the genetic basis of human diseases, with expertise in combining population genetics, genetic epidemiology and functional genomics approaches. Prior to his position at Center for Genetic Epidemiology, Steven was a postdoc and a research associate at the Harvard School of Public Health and in the Program in Medical and Population Genetics at the Broad Institute in the group of Alkes Price. Steven obtained his Ph.D. at the Fondation Jean Dausset CEPH, under the guidance of Anne-Louise Leutenegger and Emmanuelle Génin, while working as a statistical geneticist in Paris Hospitals. His current lab website can be found at https://gazal-lab.org.

Research Funding

  • Characterizing genetic signatures of natural selection to understand human diseases
    NIH · R35GM147789 · Aug 1, 2022 – Jul 31, 2027 · Role: Principal Investigator
  • From common to rare variant functional architectures of human diseases
    NIH · R00HG010160 · Aug 12, 2020 – May 31, 2023 · Role: Principal Investigator
  • From common to rare variant functional architectures of human diseases
    NIH · K99HG010160 · Sep 7, 2018 – Jun 30, 2020 · Role: Principal Investigator

Publications

  • Genome-wide association study and predictors of neonatal blood cell traits in Hispanic newborns. Am J Hum Genet. 2026 Jul 01.. View in PubMed
  • Annotation-Based Gene-Peak Links Improve Regulatory Network Prediction of Gene Expression in Human Kidney Multi-Omics. bioRxiv. 2026 Jun 17.. View in PubMed
  • Pleiotropic shared heritability quantifies the shared genetic variance of common diseases. Nat Genet. 2026 Jun; 58(6):1248-1257.. View in PubMed
  • Publisher Correction: Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting. Nat Genet. 2026 May; 58(5):1186.. View in PubMed
  • Ancient DNA reveals pervasive directional selection across West Eurasia. Nature. 2026 Jun; 654(8118):419-428.. View in PubMed
  • Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting. Nat Genet. 2026 Apr; 58(4):810-820.. View in PubMed
  • Late-Onset Rheumatoid Arthritis and Air Pollution in a Multiethnic Cohort. Arthritis Rheumatol. 2026 Jul; 78(7):1425-1436.. View in PubMed
  • Single-cell full-length transcriptome of human lung reveals genetic effects on isoform regulation beyond gene-level expression. bioRxiv. 2026 Mar 30.. View in PubMed
  • SCN2A variants are associated with familial and sporadic hemiplegic migraine. Brain. 2026 Mar 26.. View in PubMed
  • Evaluating genetic ancestry inference from single-cell transcriptomic datasets. HGG Adv. 2026 Apr 09; 7(2):100564.. View in PubMed