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Steven Yong Cen, PhD

Professor of Research Radiology, Neurology and Radiation Oncology

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Phone +1 323 442 1570
Email [email protected]
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Publications

  • Traumatic brain injury and post-traumatic stress disorder on brain imaging markers and cognition in a war veterans population. J Alzheimers Dis. 2026 Jul; 112(1):440-451.. View in PubMed
  • Radiogenomic analysis of muscle-invasive bladder cancer using CT-based texture analysis. Bladder Cancer. 2026 Apr-Jun; 12(2):23523735261455396.. View in PubMed
  • Metabolic and Molecular Correlates of Medulloblastoma: Identification of Molecular Groups Using In Vivo 1H-MR Spectroscopy. Neuro Oncol. 2026 May 14.. View in PubMed
  • MRI-based machine learning model to distinguish hippocampal sclerosis (HS) ILAE type 1 and no HS gliosis only in medial temporal lobe epilepsy. Epilepsy Res. 2026 Jun; 224:107801.. View in PubMed
  • Training Feedback Tailored to Technical Skills Expedites Proficiency in Performing Watertight Vesicourethral Anastomoses: A Randomized Controlled Trial. J Surg Educ. 2026 May; 83(5):103937.. View in PubMed
  • Machine learning based classification of aggressive and malignant renal tumors from multimodal data. PLOS Digit Health. 2026 Feb; 5(2):e0001225.. View in PubMed
  • Gene-body DNA methylation of ONECUT2 predicts its expression and prostate cancer aggressiveness in needle biopsies. Biomark Res. 2026 Jan 16; 14(1):18.. View in PubMed
  • Multiphase CT-Based Tumor and Peritumoral Radiomics for Characterization of Clear Cell Renal Cell Carcinoma. J Imaging Inform Med. 2026 Jan 05.. View in PubMed
  • Influence of scan mode, tilt, and radiation dose on CT radiomic metrics. J Appl Clin Med Phys. 2026 Jan; 27(1):e70462.. View in PubMed
  • Elucidating Distinct and Common fMRI-Complexity Patterns in Preadolescent Children With Attention-Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Obsessive-Compulsive Disorder. JAACAP Open. 2026 Apr; 4(2):254-267.. View in PubMed
  • Generative diffusion model enables quantification of calibration-free arterial spin labeling perfusion magnetic resonance imaging data in an Alzheimer’s disease cohort. Alzheimers Dement (Amst). 2025 Oct-Dec; 17(4):e70214.. View in PubMed
  • Multiparametric Dynamic Contrast Imaging for Voxelwise Quantitative Assessment of Brain Tumors. Radiol Imaging Cancer. 2025 09; 7(5):e250049.. View in PubMed
  • Advancing 1.5T MR imaging: toward achieving 3T quality through deep learning super-resolution techniques. Front Hum Neurosci. 2025; 19:1532395.. View in PubMed
  • Prediction of PD-L1 and CD68 in Clear Cell Renal Cell Carcinoma with Green Learning. J Imaging. 2025 Jun 10; 11(6).. View in PubMed
  • Integrated Hyperparameter Optimization with Dimensionality Reduction and Clustering for Radiomics: A Bootstrapped Approach. Multimodal Technol Interact. 2025 May; 9(5).. View in PubMed
  • Deep learning-based detection and segmentation of osseous metastatic prostate cancer lesions on computed tomography. Eur J Radiol Artif Intell. 2025 Jun; 2.. View in PubMed
  • Idiopathic Granulomatous Mastitis: Imaging Findings and Outcomes with Nonsteroidal Treatment in a Predominantly Hispanic Population. J Breast Imaging. 2025 Jan 25; 7(1):63-74.. View in PubMed
  • Elucidating distinct and common fMRI-complexity patterns in pre-adolescent children with Attention-Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Obsessive-Compulsive Disorder diagnoses. medRxiv. 2025 Jan 18.. View in PubMed
  • MRI free water mediates the association between diffusion tensor image analysis along the perivascular space and executive function in four independent middle to aged cohorts. Alzheimers Dement. 2025 02; 21(2):e14453.. View in PubMed
  • Human AI collaboration for unsupervised categorization of live surgical feedback. NPJ Digit Med. 2024 Dec 20; 7(1):372.. View in PubMed
  • Interleaved flow-sensitive dephasing (iFSD): Toward enhanced blood flow suppression and preserved T1 weighting and overall signals in 3D TSE-based neuroimaging. Magn Reson Med. 2025 May; 93(5):1911-1923.. View in PubMed
  • The QIBA Profile for Dynamic Susceptibility Contrast MRI Quantitative Imaging Biomarkers for Assessing Gliomas. Radiology. 2024 12; 313(3):e232555.. View in PubMed
  • Randomized Control Trial Evaluating Different Modalities of Real-Time Surgical Feedback. Curr Probl Surg. 2025 Jan; 62:101666.. View in PubMed
  • Simultaneous multi-slice cardiac real-time MRI at 0.55T. Magn Reson Med. 2025 Apr; 93(4):1723-1732.. View in PubMed
  • Age-related decline in blood-brain barrier function is more pronounced in males than females in parietal and temporal regions. Elife. 2024 Nov 04; 13.. View in PubMed
  • Deep Learning Denoising Improves CT Perfusion Image Quality in the Setting of Lower Contrast Dosing: A Feasibility Study. AJNR Am J Neuroradiol. 2024 10 03; 45(10):1468-1474.. View in PubMed
  • Diffusion model enables quantitative CBF analysis of Alzheimer’s Disease. medRxiv. 2024 Jul 03.. View in PubMed
  • Immunonutrition with Omega-3 Fatty Acid Supplementation in Severe TBI: Retrospective Analysis of Patient Characteristics and Outcomes. Neurotrauma Rep. 2024; 5(1):574-583.. View in PubMed
  • Age-Related Decline in Blood-Brain Barrier Function is More Pronounced in Males than Females in Parietal and Temporal Regions. bioRxiv. 2024 Jun 11.. View in PubMed
  • Persistent Inequities in Intravenous Thrombolysis for Acute Ischemic Stroke in the United States: Results From the Nationwide Inpatient Sample. J Am Heart Assoc. 2024 05 07; 13(9):e033316.. View in PubMed
  • Assessment of arterial pulsatility of cerebral perforating arteries using 7T high-resolution dual-VENC phase-contrast MRI. Magn Reson Med. 2024 08; 92(2):605-617.. View in PubMed
  • An Objective Computer-Assisted Measurement of Sonographic Renal Cortical Echogenicity: The Splenorenal Index. Ultrasound Q. 2024 Mar 01; 40(1):56-60.. View in PubMed
  • Technical and clinical considerations of a physical liver phantom for CT radiomics analysis. J Appl Clin Med Phys. 2024 Apr; 25(4):e14309.. View in PubMed
  • Competency in Robotic Surgery: Standard Setting for Robotic Suturing Using Objective Assessment and Expert Evaluation. J Surg Educ. 2024 03; 81(3):422-430.. View in PubMed
  • Artificial Intelligence-Based Video Feedback to Improve Novice Performance on Robotic Suturing Skills: A Pilot Study. J Endourol. 2024 Aug; 38(8):884-891.. View in PubMed
  • Pseudocirrhosis: A Case Series with Clinical and Radiographic Correlation and Review of the Literature. Dig Dis Sci. 2024 Mar; 69(3):1004-1014.. View in PubMed
  • Effect of Genetic Risk on the Relationship Between rs-fMRI Complexity and Tau and Amyloid PET in Alzheimer’s Disease. J Alzheimers Dis. 2024; 101(2):429-435.. View in PubMed
  • Author Correction: Toward precision medicine using a “digital twin” approach: modeling the onset of disease-specific brain atrophy in individuals with multiple sclerosis. Sci Rep. 2023 Dec 15; 13(1):22334.. View in PubMed
  • Investigating the role of imaging factors in the variability of CT-based texture analysis metrics. J Appl Clin Med Phys. 2024 Apr; 25(4):e14192.. View in PubMed
  • Immunonutrition with Omega-3 Fatty Acid Supplementation in Severe TBI: Retrospective Analysis of Patient Characteristics and Outcomes. Res Sq. 2023 Nov 07.. View in PubMed
  • Persistent Inequities in Intravenous Thrombolysis for Acute Ischemic Stroke in the United States: Results from the Nationwide Inpatient Sample. medRxiv. 2023 Oct 10.. View in PubMed
  • Toward precision medicine using a “digital twin” approach: modeling the onset of disease-specific brain atrophy in individuals with multiple sclerosis. Sci Rep. 2023 09 28; 13(1):16279.. View in PubMed
  • A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength. Front Oncol. 2023; 13:1156843.. View in PubMed
  • Radiomics Correlation to CD68+ Tumor-Associated Macrophages in Clear Cell Renal Cell Carcinoma. Oncology. 2024; 102(3):260-270.. View in PubMed
  • Spatial assessments in texture analysis: what the radiologist needs to know. Front Radiol. 2023; 3:1240544.. View in PubMed
  • Technical surgical skill assessment of neurovascular bundle dissection and urinary continence recovery after robotic-assisted radical prostatectomy. JU Open Plus. 2023 Aug; 1(8).. View in PubMed
  • A Multi-institution Study on the Association of Virtual Reality Skills with Continence Recovery after Robot-assisted Radical Prostatectomy. Eur Urol Focus. 2023 11; 9(6):1044-1051.. View in PubMed
  • Development of a Classification System for Live Surgical Feedback. JAMA Netw Open. 2023 06 01; 6(6):e2320702.. View in PubMed
  • Sarcopenia and body fat change as risk factors for radiologic incisional hernia following robotic nephrectomy. Skeletal Radiol. 2023 Dec; 52(12):2469-2477.. View in PubMed
  • Toward AI-supported US Triage of Women with Palpable Breast Lumps in a Low-Resource Setting. Radiology. 2023 05; 307(4):e223351.. View in PubMed
  • Toward Precision Medicine Using a “Digital Twin” Approach: Modeling the Onset of Disease-Specific Brain Atrophy in Individuals with Multiple Sclerosis. Res Sq. 2023 May 02.. View in PubMed
  • Radiogenomic Associations Clear Cell Renal Cell Carcinoma: An Exploratory Study. Oncology. 2023; 101(6):375-388.. View in PubMed
  • Cell-free DNA Methylation as a Predictive Biomarker of Response to Neoadjuvant Chemotherapy for Patients with Muscle-invasive Bladder Cancer in SWOG S1314. Eur Urol Oncol. 2023 10; 6(5):516-524.. View in PubMed
  • More extensive white matter disruptions present in untreated obstructive sleep apnea than we thought: A large sample diffusion imaging study. Hum Brain Mapp. 2023 06 01; 44(8):3045-3056.. View in PubMed
  • Work-Life Experience of Academic Radiologists: Food for Thought. Acad Radiol. 2023 04; 30(4):579-584.. View in PubMed
  • Predicting Soft Tissue Sarcoma Response to Neoadjuvant Chemotherapy Using an MRI-Based Delta-Radiomics Approach. Mol Imaging Biol. 2023 08; 25(4):776-787.. View in PubMed
  • FMRI Complexity Correlates with Tau-PET and Cognitive Decline in Late-Onset and Autosomal Dominant Alzheimer’s Disease. J Alzheimers Dis. 2023; 95(2):437-451.. View in PubMed
  • An Assessment Tool to Provide Targeted Feedback to Robotic Surgical Trainees: Development and Validation of the End-To-End Assessment of Suturing Expertise (EASE). Urol Pract. 2022 Nov; 9(6):532-539.. View in PubMed
  • Reply by Authors. Urol Pract. 2022 11; 9(6):541.. View in PubMed
  • Feasibility of using CT radiomic signatures for predicting CD8-T cell infiltration and PD-L1 expression in renal cell carcinoma. Eur J Radiol Open. 2022; 9:100440.. View in PubMed
  • Machine Learning to Delineate Surgeon and Clinical Factors That Anticipate Positive Surgical Margins After Robot-Assisted Radical Prostatectomy. J Endourol. 2022 09; 36(9):1192-1198.. View in PubMed
  • Radiomics quality score in renal masses: a systematic assessment on current literature. Br J Radiol. 2022 Sep 01; 95(1137):20211211.. View in PubMed
  • Educational, psychosocial, and clinical impact of SARS-CoV-2 (COVID-19) pandemic on medical students in the United States. World J Virol. 2022 May 25; 11(3):150-169.. View in PubMed
  • Sex Differences in Intracranial Atherosclerosis in Patients With Hypertension With Acute Ischemic Stroke. J Am Heart Assoc. 2022 05 17; 11(10):e025579.. View in PubMed
  • Reply by Authors. J Urol. 2022 08; 208(2):423-424.. View in PubMed
  • The Relationship Between Technical Skills, Cognitive Workload, and Errors During Robotic Surgical Exercises. J Endourol. 2022 05; 36(5):712-720.. View in PubMed
  • Tailored Feedback Based on Clinically Relevant Performance Metrics Expedites the Acquisition of Robotic Suturing Skills-An Unblinded Pilot Randomized Controlled Trial. J Urol. 2022 08; 208(2):414-424.. View in PubMed
  • Non-Invasive Profiling of Advanced Prostate Cancer via Multi-Parametric Liquid Biopsy and Radiomic Analysis. Int J Mol Sci. 2022 Feb 25; 23(5).. View in PubMed
  • [Hyperactivation of PI3K/AKT/mTOR signal pathway impairs TNF-α-induced autophagy in mesenchymal stem cells from patients with ankylosing spondylitis]. Nan Fang Yi Ke Da Xue Xue Bao. 2022 Feb 20; 42(2):272-277.. View in PubMed
  • Technical Skill Impacts the Success of Sequential Robotic Suturing Substeps. J Endourol. 2022 02; 36(2):273-278.. View in PubMed
  • Characterizing breast masses using an integrative framework of machine learning and CEUS-based radiomics. J Ultrasound. 2022 Sep; 25(3):699-708.. View in PubMed
  • Utility of Contrast-Enhanced Ultrasound and 4-Dimensional Computed Tomography for Preoperative Detection and Localization of Parathyroid Adenomas Compared With Surgical Results. J Ultrasound Med. 2022 Sep; 41(9):2295-2306.. View in PubMed
  • Association Between Glycemic Gap and In-hospital Outcomes in Aneurysmal Subarachnoid Hemorrhage. Front Neurol. 2021; 12:714341.. View in PubMed
  • CT-based radiomics stratification of tumor grade and TNM stage of clear cell renal cell carcinoma. Eur Radiol. 2022 Apr; 32(4):2552-2563.. View in PubMed
  • Minocycline decreases blood-brain barrier permeability following aneurysmal subarachnoid hemorrhage: a randomized, double-blind, controlled trial. J Neurosurg. 2022 May 01; 136(5):1251-1259.. View in PubMed
  • Benchmarking Various Radiomic Toolkit Features While Applying the Image Biomarker Standardization Initiative toward Clinical Translation of Radiomic Analysis. J Digit Imaging. 2021 10; 34(5):1156-1170.. View in PubMed
  • A Radiomic-based Machine Learning Algorithm to Reliably Differentiate Benign Renal Masses from Renal Cell Carcinoma. Eur Urol Focus. 2022 07; 8(4):988-994.. View in PubMed
  • Predicting clinical outcomes in COVID-19 using radiomics on chest radiographs. Br J Radiol. 2021 Oct 01; 94(1126):20210221.. View in PubMed
  • Development and validation of an objective scoring tool to evaluate surgical dissection: Dissection Assessment for Robotic Technique (DART). Urol Pract. 2021 Sep; 8(5):596-604.. View in PubMed
  • Accuracy of contrast-enhanced spectral mammography compared with MRI for invasive breast cancers: Prospective study in population of predominantly underrepresented minorities. Clin Imaging. 2021 Dec; 80:364-370.. View in PubMed
  • Reply by Authors. Urol Pract. 2021 Sep; 8(5):604.. View in PubMed
  • Addressing ethnic disparities in imaging utilization and clinical outcomes for COVID-19. Clin Imaging. 2021 Sep; 77:276-282.. View in PubMed
  • Whole-tumor 3D volumetric MRI-based radiomics approach for distinguishing between benign and malignant soft tissue tumors. Eur Radiol. 2021 Nov; 31(11):8522-8535.. View in PubMed
  • Reply to “Impact of COVID-19 on the mental health of radiologists”. Clin Imaging. 2021 11; 79:102-103.. View in PubMed
  • Surgeon Automated Performance Metrics as Predictors of Early Urinary Continence Recovery After Robotic Radical Prostatectomy-A Prospective Bi-institutional Study. Eur Urol Open Sci. 2021 May; 27:65-72.. View in PubMed
  • Machine learning based predictors for COVID-19 disease severity. Sci Rep. 2021 02 25; 11(1):4673.. View in PubMed
  • Assessment of carotid stiffness by measuring carotid pulse wave velocity using a single-slice oblique-sagittal phase-contrast MRI. Magn Reson Med. 2021 07; 86(1):442-455.. View in PubMed
  • Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease. Front Neurosci. 2021; 15:627627.. View in PubMed
  • Identification of robust and reproducible CT-texture metrics using a customized 3D-printed texture phantom. J Appl Clin Med Phys. 2021 Feb; 22(2):98-107.. View in PubMed
  • Transoral Robotic Surgery (TORS) Versus Non-TORS Tongue Resection for Obstructive Sleep Apnea. Laryngoscope. 2021 05; 131(5):E1735-E1740.. View in PubMed
  • The Children’s Health and Maintenance Program (CHAMP): An innovative community outreach oral health promotion program: A randomized trial. Community Dent Oral Epidemiol. 2021 04; 49(2):192-200.. View in PubMed
  • Daily Ultrasound Imaging for Patients Undergoing Postprostatectomy Radiation Therapy Predicts and Ensures Dosimetric Endpoints. Adv Radiat Oncol. 2020 Nov-Dec; 5(6):1206-1212.. View in PubMed
  • Impacts of the Coronavirus Disease 2019 (COVID-19) pandemic on healthcare workers: A nationwide survey of United States radiologists. Clin Imaging. 2020 Dec; 68:218-225.. View in PubMed
  • Shape and texture-based radiomics signature on CT effectively discriminates benign from malignant renal masses. Eur Radiol. 2021 Feb; 31(2):1011-1021.. View in PubMed
  • Natural History of Radiologic Incisional Hernia Following Robotic Nephrectomy. J Endourol. 2020 09; 34(9):974-980.. View in PubMed
  • Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis. J Neuroinflammation. 2020 Jun 15; 17(1):189.. View in PubMed
  • Deep learning based classification of solid lipid-poor contrast enhancing renal masses using contrast enhanced CT. Br J Radiol. 2020 Jul; 93(1111):20200002.. View in PubMed
  • Quantitative magnetic resonance imaging (q-MRI) for the assessment of soft-tissue sarcoma treatment response: a narrative case review of technique development. Clin Imaging. 2020 Jul; 63:83-93.. View in PubMed
  • Feasibility of coronary endothelial function assessment using arterial spin labeled CMR. NMR Biomed. 2020 02; 33(2):e4183.. View in PubMed
  • Tricuspid Annular Diameter Measurement on Routine Chest CT Can Detect Significant Tricuspid Regurgitation. AJR Am J Roentgenol. 2019 12; 213(6):W257-W263.. View in PubMed

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