Keck School Faculty

Toby Maher

Toby Maher

Professor of Clinical Medicine
Medicine
IRD 720 2020 Zonal Avenue Health Sciences Campus los angeles

Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis Thorax. 2022 Aug; 77(8):829-833. . View in PubMed

Biomarkers for Interstitial Lung Abnormalities: A Stepping-stone Toward Idiopathic Pulmonary Fibrosis Prevention? Am J Respir Crit Care Med. 2022 Aug 01; 206(3):244-246.. View in PubMed

ACR Open Rheumatol. 2022 Jul 19. . View in PubMed

Decline in forced vital capacity in subjects with systemic sclerosis-associated interstitial lung disease in the SENSCIS trial compared with healthy reference subjects Respir Res. 2022 Jul 05; 23(1):178. . View in PubMed

Meta-Analysis of Effect of Nintedanib on Reducing FVC Decline Across Interstitial Lung Diseases Adv Ther. 2022 Jul; 39(7):3392-3402. . View in PubMed

Genome-wide Enrichment of TERT Rare Variants in IPF Patients of Latino Ancestry Am J Respir Crit Care Med. 2022 Jun 06. . View in PubMed

Lung function trajectory in progressive fibrosing interstitial lung disease Eur Respir J. 2022 Jun; 59(6). . View in PubMed

Impact of lung function and baseline clinical characteristics on patient-reported outcome measures in systemic sclerosis-associated interstitial lung disease Rheumatology (Oxford). 2022 May 31. . View in PubMed

Reply to: The Need for a CYFRA 21-1 Cut-off Value to Predict Clinical Progression of IPF in Clinical Practice Am J Respir Crit Care Med. 2022 May 18. . View in PubMed

Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis Thorax. 2022 May 09. . View in PubMed

Thoracic Involvement in Systemic Autoimmune Rheumatic Diseases: Pathogenesis and Management Clin Rev Allergy Immunol. 2022 Mar 18. . View in PubMed

PAciFy Cough-a multicentre, double-blind, placebo-controlled, crossover trial of morphine sulphate for the treatment of pulmonary Fibrosis Cough Trials. 2022 Mar 02; 23(1):184. . View in PubMed

The role of precision medicine in interstitial lung disease Eur Respir J. 2022 Feb 03. . View in PubMed

Short-term lung function changes predict mortality in patients with fibrotic hypersensitivity pneumonitis Respirology. 2022 03; 27(3):202-208. . View in PubMed

Clinical Utility of Home versus Hospital Spirometry in Fibrotic Interstitial Lung Disease: Evaluation after INJUSTIS Interim Analysis Ann Am Thorac Soc. 2022 03; 19(3):506-509. . View in PubMed

Biomarker signatures for progressive idiopathic pulmonary fibrosis Eur Respir J. 2022 03; 59(3). . View in PubMed

Pulmonary Rehabilitation in Idiopathic Pulmonary Fibrosis and COPD: A Propensity-Matched Real-World Study Chest. 2022 03; 161(3):728-737. . View in PubMed

Using Data on Survival with Idiopathic Pulmonary Fibrosis to Estimate Survival with Other Types of Progressive Fibrosis Interstitial Lung Disease: A Bayesian Framework Adv Ther. 2022 02; 39(2):1045-1054. . View in PubMed

Effects of nintedanib by inclusion criteria for progression of interstitial lung disease Eur Respir J. 2022 02; 59(2). . View in PubMed

Pirfenidone in Unclassifiable Interstitial Lung Disease: A Subgroup Analysis by Concomitant Mycophenolate Mofetil and/or Previous Corticosteroid Use Adv Ther. 2022 02; 39(2):1081-1095. . View in PubMed

Integrating Clinical Probability into the Diagnostic Approach to Idiopathic Pulmonary Fibrosis: An International Working Group Perspective Am J Respir Crit Care Med. 2022 08 01; 206(3):247-259. . View in PubMed

CYFRA 21-1 Predicts Progression in Idiopathic Pulmonary Fibrosis: A Prospective Longitudinal Analysis of the PROFILE Cohort Am J Respir Crit Care Med. 2022 06 15; 205(12):1440-1448. . View in PubMed

Phase 2B Study of Inhaled RVT-1601 for Chronic Cough in Idiopathic Pulmonary Fibrosis: A Multicenter, Randomized, Placebo-controlled Study (SCENIC Trial) Am J Respir Crit Care Med. 2022 05 01; 205(9):1084-1092. . View in PubMed

Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis N Engl J Med. 2022 06 09; 386(23):2178-2187. . View in PubMed

Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline Am J Respir Crit Care Med. 2022 05 01; 205(9):e18-e47. . View in PubMed

Efficacy of Pirfenidone vsPlacebo in Unclassifiable Interstitial Lung Disease, by Surgical Lung Biopsy Status: Data From a post-hoc Analysis. Front Med (Lausanne). 2022; 9:897102. . View in PubMed

Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2022 03 01; 205(5):550-562. . View in PubMed

Fatum Inexorabile: Do Monocytes Predict the Fate of Interstitial Lung Abnormalities? Am J Respir Crit Care Med. 2022 04 01; 205(7):743-744.. View in PubMed

Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2022 07 01; 206(1):56-69. . View in PubMed

Autoantibodies are present in the bronchoalveolar lavage but not circulation in patients with fibrotic interstitial lung disease ERJ Open Res. 2022 Jan; 8(1). . View in PubMed

Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD) BMJ Open Respir Res. 2021 Dec; 8(1). . View in PubMed

Global incidence and prevalence of idiopathic pulmonary fibrosis Respir Res. 2021 Jul 07; 22(1):197. . View in PubMed

Worldwide experiences and opinions of healthcare providers on eHealth for patients with interstitial lung diseases in the COVID-19 era ERJ Open Res. 2021 Jul; 7(3). . View in PubMed

50-gene risk profiles in peripheral blood predict COVID-19 outcomes: A retrospective, multicenter cohort study EBioMedicine. 2021 Jul; 69:103439. . View in PubMed

Respir Res. 2021 Feb 05; 22(1):38. . View in PubMed

Reply Arthritis Rheumatol. 2021 12; 73(12):2354-2355. . View in PubMed

Measurement of hypoxia in the lung in idiopathic pulmonary fibrosis: an F-MISO PET/CT study Eur Respir J. 2021 10; 58(4). . View in PubMed

Targeting Human Herpesviruses: An Effective Strategy for Treating Idiopathic Pulmonary Fibrosis? Ann Am Thorac Soc. 2021 08; 18(8):1285-1286.. View in PubMed

Home spirometry in patients with idiopathic pulmonary fibrosis: data from the INMARK trial Eur Respir J. 2021 07; 58(1). . View in PubMed

Circulating fibrocytes are not disease-specific prognosticators in idiopathic pulmonary fibrosis Eur Respir J. 2021 07; 58(1). . View in PubMed

Idiopathic pulmonary fibrosis: Disease mechanisms and drug development Pharmacol Ther. 2021 06; 222:107798. . View in PubMed

Serum markers of pulmonary epithelial damage in systemic sclerosis-associated interstitial lung disease and disease progression Respirology. 2021 05; 26(5):461-468. . View in PubMed

Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis Eur Respir J. 2021 05; 57(5). . View in PubMed

Effect of Nintedanib on Lung Function in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease: Further Analyses of a Randomized, Double-Blind, Placebo-Controlled Trial Arthritis Rheumatol. 2021 04; 73(4):671-676. . View in PubMed

Phase 2 trial to assess lebrikizumab in patients with idiopathic pulmonary fibrosis Eur Respir J. 2021 02; 57(2). . View in PubMed

Efficacy and safety of nintedanib in patients with systemic sclerosis-associated interstitial lung disease treated with mycophenolate: a subgroup analysis of the SENSCIS trial Lancet Respir Med. 2021 01; 9(1):96-106. . View in PubMed

Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis Thorax. 2021 01; 76(1):73-82. . View in PubMed

Small Airways in Idiopathic Pulmonary Fibrosis: Quiet but Not Forgotten Am J Respir Crit Care Med. 2021 11 01; 204(9):1010-1011. . View in PubMed

Patient-centered Outcomes Research in Interstitial Lung Disease: An Official American Thoracic Society Research Statement Am J Respir Crit Care Med. 2021 07 15; 204(2):e3-e23. . View in PubMed

Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells Am J Respir Crit Care Med. 2021 07 15; 204(2):197-208. . View in PubMed

Monocyte Count as a Prognostic Biomarker in Patients with Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2021 07 01; 204(1):74-81. . View in PubMed

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations Am J Respir Crit Care Med. 2021 03 15; 203(6):775-778. . View in PubMed

The Respiratory Microbiome in Chronic Hypersensitivity Pneumonitis Is Distinct from That of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2021 02 01; 203(3):339-347. . View in PubMed

Management of Acute Exacerbation of Idiopathic Pulmonary Fibrosis in Specialised and Non-specialised ILD Centres Around the World Front Med (Lausanne). 2021; 8:699644. . View in PubMed

DNA Methylome Alterations Are Associated with Airway Macrophage Differentiation and Phenotype during Lung Fibrosis Am J Respir Crit Care Med. 2021 10 15; 204(8):954-966. . View in PubMed

Enhanced IL-1ß Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis Front Immunol. 2021; 12:661811. . View in PubMed

Muscle stimulation in advanced idiopathic pulmonary fibrosis: a randomised placebo-controlled feasibility study BMJ Open. 2021 06 02; 11(6):e048808. . View in PubMed

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis Commun Biol. 2021 03 23; 4(1):392. . View in PubMed

Assessment of recent evidence for the management of patients with systemic sclerosis-associated interstitial lung disease: a systematic review ERJ Open Res. 2021 Jan; 7(1). . View in PubMed

BAL Is Safe and Well Tolerated in Individuals with Idiopathic Pulmonary Fibrosis: An Analysis of the PROFILE Study Am J Respir Crit Care Med. 2021 01 01; 203(1):136-139. . View in PubMed

Itaconate controls the severity of pulmonary fibrosis Sci Immunol. 2020 Oct 23; 5(52). . View in PubMed

Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis Nat Commun. 2020 Sep 11; 11(1):4680. . View in PubMed

Shedding light on developmental drugs for idiopathic pulmonary fibrosis Expert Opin Investig Drugs. 2020 Aug; 29(8):797-808. . View in PubMed

The need for a holistic approach for SSc-ILD - achievements and ambiguity in a devastating disease Respir Res. 2020 Jul 23; 21(1):197. . View in PubMed

Chronic hypersensitivity pneumonitis; an enigmatic and frequently fatal disease Eur Respir Rev. 2020 Jun 30; 29(156). . View in PubMed

Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease Clin Rheumatol. 2020 Apr; 39(4):1173-1179. . View in PubMed

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled avß6 integrin inhibitor Respir Res. 2020 Mar 26; 21(1):75. . View in PubMed

Health-related quality of life and symptoms in patients with IPF treated with nintedanib: analyses of patient-reported outcomes from the INPULSIS® trials Respir Res. 2020 Jan 30; 21(1):36. . View in PubMed

Opportunities to diagnose fibrotic lung diseases in routine care: A primary care cohort study Respirology. 2020 12; 25(12):1274-1282. . View in PubMed

Safety and tolerability of nintedanib in patients with systemic sclerosis-associated interstitial lung disease: data from the SENSCIS trial Ann Rheum Dis. 2020 11; 79(11):1478-1484. . View in PubMed

Mixed Ventilatory Defects in Pulmonary Sarcoidosis: Prevalence and Clinical Features Chest. 2020 11; 158(5):2007-2014. . View in PubMed

Interaction between the promoter MUC5B polymorphism and mucin expression: is there a difference according to ILD subtype? Thorax. 2020 10; 75(10):901-903.. View in PubMed

Pulmonary fibrosis secondary to COVID-19: a call to arms? Lancet Respir Med. 2020 08; 8(8):750-752.. View in PubMed

Diagnostic and Prognostic Biomarkers for Chronic Fibrosing Interstitial Lung Diseases With a Progressive Phenotype Chest. 2020 08; 158(2):646-659. . View in PubMed

Pleuroparenchymal fibroelastosis in systemic sclerosis: prevalence and prognostic impact Eur Respir J. 2020 07; 56(1). . View in PubMed

Healthcare Resources Utilization and Costs of Patients with Non-IPF Progressive Fibrosing Interstitial Lung Disease Based on Insurance Claims in the USA Adv Ther. 2020 07; 37(7):3292-3298. . View in PubMed

Healthcare Resource Utilization Among Patients in England with Systemic Sclerosis-Associated Interstitial Lung Disease: A Retrospective Database Analysis Adv Ther. 2020 05; 37(5):2460-2476. . View in PubMed

Predictors of progression in systemic sclerosis patients with interstitial lung disease Eur Respir J. 2020 05; 55(5). . View in PubMed

Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent Eur Respir J. 2020 04; 55(4). . View in PubMed

Clinical quantification of the integrin avß6 by [18F]FB-A20FMDV2 positron emission tomography in healthy and fibrotic human lung (PETAL Study) Eur J Nucl Med Mol Imaging. 2020 04; 47(4):967-979. . View in PubMed

Acute exacerbation of idiopathic pulmonary fibrosis: international survey and call for harmonisation Eur Respir J. 2020 04; 55(4). . View in PubMed

Physiological predictors of exertional oxygen desaturation in patients with fibrotic interstitial lung disease Eur Respir J. 2020 02; 55(2). . View in PubMed

Cost-effectiveness of ambulatory oxygen in improving quality of life in fibrotic lung disease: preliminary evidence from the AmbOx Trial Eur Respir J. 2020 02; 55(2). . View in PubMed

Pirfenidone in patients with unclassifiable progressive fibrosing interstitial lung disease: a double-blind, randomised, placebo-controlled, phase 2 trial Lancet Respir Med. 2020 02; 8(2):147-157. . View in PubMed

Treatment of Acute Exacerbation of Idiopathic Pulmonary FibrosisA Call to Arms. Am J Respir Crit Care Med. 2020 05 01; 201(9):1030-1032. . View in PubMed

Effect of Co-trimoxazole (Trimethoprim-Sulfamethoxazole) vs Placebo on Death, Lung Transplant, or Hospital Admission in Patients With Moderate and Severe Idiopathic Pulmonary Fibrosis: The EME-TIPAC Randomized Clinical Trial JAMA. 2020 12 08; 324(22):2282-2291. . View in PubMed

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2020 03 01; 201(5):564-574. . View in PubMed

Translational pharmacology of an inhaled small molecule avß6 integrin inhibitor for idiopathic pulmonary fibrosis Nat Commun. 2020 09 16; 11(1):4659. . View in PubMed

Dynamics of human monocytes and airway macrophages during healthy aging and after transplant J Exp Med. 2020 03 02; 217(3). . View in PubMed

The Role of the Lung's Microbiome in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis Int J Mol Sci. 2019 Nov 10; 20(22). . View in PubMed

Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat Respir Res. 2019 Sep 06; 20(1):205. . View in PubMed

Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort Respir Res. 2019 Jul 12; 20(1):148. . View in PubMed

Influence of Idiopathic Pulmonary Fibrosis Progression on Healthcare Resource Use Pharmacoecon Open. 2019 Mar; 3(1):81-91. . View in PubMed

Modelling Forced Vital Capacity in Idiopathic Pulmonary Fibrosis: Optimising Trial Design Adv Ther. 2019 11; 36(11):3059-3070. . View in PubMed

Current and future perspectives on management of systemic sclerosis-associated interstitial lung disease Expert Rev Clin Immunol. 2019 10; 15(10):1009-1017. . View in PubMed

King's Brief Interstitial Lung Disease questionnaire: responsiveness and minimum clinically important difference Eur Respir J. 2019 09; 54(3). . View in PubMed

Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis Eur Respir J. 2019 09; 54(3). . View in PubMed

Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study Lancet Respir Med. 2019 09; 7(9):771-779. . View in PubMed

Potential of nintedanib in treatment of progressive fibrosing interstitial lung diseases Eur Respir J. 2019 09; 54(3). . View in PubMed

Variable utility of mosaic attenuation to distinguish fibrotic hypersensitivity pneumonitis from idiopathic pulmonary fibrosis Eur Respir J. 2019 07; 54(1). . View in PubMed

Pirfenidone Treatment in Individuals with Idiopathic Pulmonary Fibrosis: Impact of Timing of Treatment Initiation Ann Am Thorac Soc. 2019 07; 16(7):927-930. . View in PubMed

Management of Fibrosing Interstitial Lung Diseases Adv Ther. 2019 07; 36(7):1518-1531. . View in PubMed

Idiopathic Pulmonary Fibrosis: New and Emerging Treatment Options Drugs Aging. 2019 06; 36(6):485-492. . View in PubMed

Can monocytes predict prognosis of idiopathic pulmonary fibrosis? Lancet Respir Med. 2019 06; 7(6):467-469.. View in PubMed

Patient-reported distress can aid clinical decision-making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort Eur Respir J. 2019 05; 53(5). . View in PubMed

In patients with idiopathic pulmonary fibrosis the presence of hiatus hernia is associated with disease progression and mortality Eur Respir J. 2019 05; 53(5). . View in PubMed

Regularized Latent Class Model for Joint Analysis of High-Dimensional Longitudinal Biomarkers and a Time-to-Event Outcome Biometrics. 2019 03; 75(1):69-77. . View in PubMed

A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis Eur Respir J. 2019 03; 53(3). . View in PubMed

Gait speed and prognosis in patients with idiopathic pulmonary fibrosis: a prospective cohort study Eur Respir J. 2019 02; 53(2). . View in PubMed

The potential impact of azithromycin in idiopathic pulmonary fibrosis Eur Respir J. 2019 02; 53(2). . View in PubMed

Proceedings of the American College of Rheumatology/Association of Physicians of Great Britain and Ireland Connective Tissue Disease-Associated Interstitial Lung Disease Summit: A Multidisciplinary Approach to Address Challenges and Opportunities Arthritis Rheumatol. 2019 02; 71(2):182-195. . View in PubMed

Lung function outcomes in the INPULSIS® trials of nintedanib in idiopathic pulmonary fibrosis Respir Med. 2019 01; 146:42-48. . View in PubMed

Predicting outcomes in rheumatoid arthritis related interstitial lung disease Eur Respir J. 2019 01; 53(1). . View in PubMed

No relevant pharmacokinetic drug-drug interaction between nintedanib and pirfenidone Eur Respir J. 2019 01; 53(1). . View in PubMed

Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 12 01; 200(11):1402-1413. . View in PubMed

Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 07 15; 200(2):199-208. . View in PubMed

The King's Brief Interstitial Lung Disease (KBILD) questionnaire: an updated minimal clinically important difference BMJ Open Respir Res. 2019; 6(1):e000363. . View in PubMed

Sarcoidosis in the UK: insights from British Thoracic Society registry data BMJ Open Respir Res. 2019; 6(1):e000357. . View in PubMed

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease N Engl J Med. 2019 06 27; 380(26):2518-2528. . View in PubMed

The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 07 15; 200(2):209-219. . View in PubMed

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung DiseaseReply. N Engl J Med. 2019 10 17; 381(16):1596-1597. . View in PubMed

Rationale, design and objectives of two phase III, randomised, placebo-controlled studies of GLPG1690, a novel autotaxin inhibitor, in idiopathic pulmonary fibrosis (ISABELA 1 and 2) BMJ Open Respir Res. 2019; 6(1):e000422. . View in PubMed

Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis Sci Transl Med. 2019 09 25; 11(511). . View in PubMed

Proceedings of the American College of Rheumatology/Association of Physicians of Great Britain and Ireland Connective Tissue Disease-Associated Interstitial Lung Disease Summit: A Multidisciplinary Approach to Address Challenges and Opportunities QJM. 2019 02 01; 112(2):81-93. . View in PubMed

Computed Tomographic Biomarkers in Idiopathic Pulmonary FibrosisThe Future of Quantitative Analysis. Am J Respir Crit Care Med. 2019 01 01; 199(1):12-21. . View in PubMed

Diagnostic Likelihood Thresholds That Define a Working Diagnosis of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 11 01; 200(9):1146-1153. . View in PubMed

The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis Nat Commun. 2019 01 02; 10(1):6. . View in PubMed

Long-term safety of pirfenidone: results of the prospective, observational PASSPORT study ERJ Open Res. 2018 Oct; 4(4). . View in PubMed

Safety and tolerability of nintedanib for the treatment of idiopathic pulmonary fibrosis in routine UK clinical practice ERJ Open Res. 2018 Oct; 4(4). . View in PubMed

Could quality be the key in connective tissue disease-associated interstitial lung disease? Respirology. 2018 Jun 13.. View in PubMed

Improved quantitation and reproducibility in multi-PET/CT lung studies by combining CT information EJNMMI Phys. 2018 Jun 05; 5(1):14. . View in PubMed

Incidence, Prevalence, and Survival of Patients with Idiopathic Pulmonary Fibrosis in the UK Adv Ther. 2018 May; 35(5):724-736. . View in PubMed

The Efficacy and Mechanism Evaluation of Treating Idiopathic Pulmonary fibrosis with the Addition of Co-trimoxazole (EME-TIPAC): study protocol for a randomised controlled trial Trials. 2018 Feb 05; 19(1):89. . View in PubMed

Prevalence and Effects of Emphysema in Never-Smokers with Rheumatoid Arthritis Interstitial Lung Disease EBioMedicine. 2018 Feb; 28:303-310. . View in PubMed

Effect of ambulatory oxygen on quality of life for patients with fibrotic lung disease (AmbOx): a prospective, open-label, mixed-method, crossover randomised controlled trial Lancet Respir Med. 2018 10; 6(10):759-770. . View in PubMed

Safety, tolerability, pharmacokinetics, and pharmacodynamics of GLPG1690, a novel autotaxin inhibitor, to treat idiopathic pulmonary fibrosis (FLORA): a phase 2a randomised placebo-controlled trial Lancet Respir Med. 2018 08; 6(8):627-635. . View in PubMed

Gazing into the crystal ball: can treatment response be predicted in IPF? Lancet Respir Med. 2018 08; 6(8):570-572.. View in PubMed

The Burden of Illness of Idiopathic Pulmonary Fibrosis: A Comprehensive Evidence Review Pharmacoeconomics. 2018 07; 36(7):779-807. . View in PubMed

Pulmonary hypertension in interstitial lung disease: Limitations of echocardiography compared to cardiac catheterization Respirology. 2018 07; 23(7):687-694. . View in PubMed

Likelihood of pulmonary hypertension in patients with idiopathic pulmonary fibrosis and emphysema Respirology. 2018 06; 23(6):593-599. . View in PubMed

Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF) Eur J Nucl Med Mol Imaging. 2018 05; 45(5):806-815. . View in PubMed

Phenotypic characteristics associated with slow gait speed in idiopathic pulmonary fibrosis Respirology. 2018 05; 23(5):498-506. . View in PubMed

Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? Lancet Respir Med. 2018 02; 6(2):154-160.. View in PubMed

Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis Sci Rep. 2018 01 30; 8(1):1906. . View in PubMed

Combination Therapy and the Start of a New Epoch for Idiopathic Pulmonary Fibrosis? Am J Respir Crit Care Med. 2018 02 01; 197(3):283-284.. View in PubMed

Identifying Barriers to Idiopathic Pulmonary Fibrosis Treatment: A Survey of Patient and Physician Views Respiration. 2018; 96(6):514-524. . View in PubMed

The topical study of inhaled drug (salbutamol) delivery in idiopathic pulmonary fibrosis Respir Res. 2018 02 06; 19(1):25. . View in PubMed

Statin Therapy and Outcomes in Trials of Nintedanib in Idiopathic Pulmonary Fibrosis Respiration. 2018; 95(5):317-326. . View in PubMed

Metformin Does Not Affect Clinically Relevant Outcomes in Patients with Idiopathic Pulmonary Fibrosis Respiration. 2018; 96(4):314-322. . View in PubMed

Rapidly Progressive Cystic Lung Disease Am J Respir Crit Care Med. 2018 07 15; 198(2):264. . View in PubMed

Predicting Outcomes in Idiopathic Pulmonary Fibrosis Using Automated Computed Tomographic Analysis Am J Respir Crit Care Med. 2018 09 15; 198(6):767-776. . View in PubMed

Investigating the effects of nintedanib on biomarkers of extracellular matrix turnover in patients with IPF: design of the randomised placebo-controlled INMARK®trial BMJ Open Respir Res. 2018; 5(1):e000325. . View in PubMed

Pirfenidone in patients with unclassifiable progressive fibrosing interstitial lung disease: design of a double-blind, randomised, placebo-controlled phase II trial BMJ Open Respir Res. 2018; 5(1):e000289. . View in PubMed

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-ß1 production Sci Transl Med. 2018 09 26; 10(460). . View in PubMed

Pleuroparenchymal Fibroelastosis: A Review of Histopathologic Features and the Relationship Between Histologic Parameters and Survival Am J Surg Pathol. 2017 Dec; 41(12):1683-1689. . View in PubMed

Towards a global initiative for fibrosis treatment (GIFT) ERJ Open Res. 2017 Oct; 3(4). . View in PubMed

Coconut oil has less satiating properties than medium chain triglyceride oil Physiol Behav. 2017 Oct 01; 179:422-426. . View in PubMed

Unmet needs in the treatment of idiopathic pulmonary fibrosis-insights from patient chart review in five European countries BMC Pulm Med. 2017 Sep 15; 17(1):124. . View in PubMed

Validity, responsiveness and minimum clinically important difference of the incremental shuttle walk in idiopathic pulmonary fibrosis: a prospective study Thorax. 2017 Sep 07. . View in PubMed

Design of a randomised, placebo-controlled clinical trial of nintedanib in patients with systemic sclerosis-associated interstitial lung disease (SENSCIS™) Clin Exp Rheumatol. 2017 Sep-Oct; 35 Suppl 106(4):75-81. . View in PubMed

The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis Oncotarget. 2017 Jul 25; 8(30):48737-48754. . View in PubMed

Nintedanib in patients with idiopathic pulmonary fibrosis and preserved lung volume Thorax. 2017 Apr; 72(4):340-346. . View in PubMed

Survival in Idiopathic Pulmonary Fibrosis: Perspectives from Pulmonary Arterial Hypertension J Manag Care Spec Pharm. 2017 Mar; 23(3-b Suppl):S3-S4. . View in PubMed

Predicting Life Expectancy for Pirfenidone in Idiopathic Pulmonary Fibrosis J Manag Care Spec Pharm. 2017 Mar; 23(3-b Suppl):S17-S24. . View in PubMed

An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study Lancet Respir Med. 2017 12; 5(12):946-955. . View in PubMed

Cough in fibrotic lung disease: An unresolved challenge Respirology. 2017 11; 22(8):1491-1492. . View in PubMed

A lesson in plasticity: a 74-year-old man with plastic bronchitis Thorax. 2017 11; 72(11):1055-1057. . View in PubMed

Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study Lancet Respir Med. 2017 11; 5(11):857-868. . View in PubMed

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study Lancet Respir Med. 2017 11; 5(11):869-880. . View in PubMed

A novel formulation of inhaled sodium cromoglicate (PA101) in idiopathic pulmonary fibrosis and chronic cough: a randomised, double-blind, proof-of-concept, phase 2 trial Lancet Respir Med. 2017 10; 5(10):806-815. . View in PubMed

Short-Term Pulmonary Function Trends Are Predictive of Mortality in Interstitial Lung Disease Associated With Systemic Sclerosis Arthritis Rheumatol. 2017 08; 69(8):1670-1678. . View in PubMed

Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: an international case-cohort study Eur Respir J. 2017 08; 50(2). . View in PubMed

Functional and prognostic effects when emphysema complicates idiopathic pulmonary fibrosis Eur Respir J. 2017 07; 50(1). . View in PubMed

Home spirometry for idiopathic pulmonary fibrosis: ready for prime time? Eur Respir J. 2017 07; 50(1).. View in PubMed

Clinical trial research in focus: why do so many clinical trials fail in IPF? Lancet Respir Med. 2017 05; 5(5):372-374.. View in PubMed

A Cost-Effectiveness Analysis of Nintedanib in Idiopathic Pulmonary Fibrosis in the UK Pharmacoeconomics. 2017 04; 35(4):479-491. . View in PubMed

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis Thorax. 2017 02; 72(2):137-147. . View in PubMed

Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis Thorax. 2017 02; 72(2):148-153. . View in PubMed

Differential Expression of VEGF-Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis Am J Respir Crit Care Med. 2017 08 15; 196(4):479-493. . View in PubMed

Changes in the respiratory microbiome during acute exacerbations of idiopathic pulmonary fibrosis Respir Res. 2017 02 01; 18(1):29. . View in PubMed

Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone Respiration. 2017; 93(6):415-423. . View in PubMed

Host-Microbial Interactions in Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2017 06 15; 195(12):1640-1650. . View in PubMed

Rituximab versus cyclophosphamide for the treatment of connective tissue disease-associated interstitial lung disease (RECITAL): study protocol for a randomised controlled trial Trials. 2017 06 15; 18(1):275. . View in PubMed

Time for an International Consensus on Hypersensitivity PneumonitisA Call to Arms. Am J Respir Crit Care Med. 2017 09 15; 196(6):665-666. . View in PubMed

Update in Interstitial Lung Disease 2016 Am J Respir Crit Care Med. 2017 07 15; 196(2):132-138. . View in PubMed

Ambulatory oxygen in fibrotic lung disease (AmbOx): study protocol for a randomised controlled trial Trials. 2017 04 28; 18(1):201. . View in PubMed

Precision medicine in idiopathic pulmonary fibrosis QJM. 2016 Sep; 109(9):585-587. . View in PubMed

Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis Clin Sci (Lond). 2016 Apr; 130(8):575-86. . View in PubMed

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