Keck School Faculty

Toby Maher
Toby Maher
Professor of Clinical Medicine
Medicine
1520 San Pablo Street Health Sciences Campus Los Angeles

Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease Clin Rheumatol. 2020 Jan 08. . View in PubMed

Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 Dec 01; 200(11):1402-1413. . View in PubMed

Physiological predictors of exertional oxygen desaturation in patients with fibrotic interstitial lung disease Eur Respir J. 2019 Nov 14. . View in PubMed

Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 Nov 11. . View in PubMed

Cost-effectiveness of Ambulatory Oxygen in improving quality of life in fibrotic lung disease: Preliminary evidence from the AmbOx Trial Eur Respir J. 2019 Nov 07. . View in PubMed

Modelling Forced Vital Capacity in Idiopathic Pulmonary Fibrosis: Optimising Trial Design Adv Ther. 2019 Nov; 36(11):3059-3070. . View in PubMed

Diagnostic Likelihood Thresholds That Define a Working Diagnosis of Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 Nov 01; 200(9):1146-1153. . View in PubMed

Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis Sci Transl Med. 2019 Sep 25; 11(511). . View in PubMed

Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat Respir Res. 2019 Sep 06; 20(1):205. . View in PubMed

King's Brief Interstitial Lung Disease questionnaire: responsiveness and minimum clinically important difference Eur Respir J. 2019 Sep; 54(3). . View in PubMed

Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study Lancet Respir Med. 2019 Sep; 7(9):771-779. . View in PubMed

Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis Eur Respir J. 2019 Sep; 54(3). . View in PubMed

Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort Respir Res. 2019 Jul 12; 20(1):148. . View in PubMed

Management of Fibrosing Interstitial Lung Diseases Adv Ther. 2019 Jul; 36(7):1518-1531. . View in PubMed

Can monocytes predict prognosis of idiopathic pulmonary fibrosis? Lancet Respir Med. 2019 Jun; 7(6):467-469.. View in PubMed

Patient-reported distress can aid clinical decision-making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort Eur Respir J. 2019 May; 53(5). . View in PubMed

In patients with idiopathic pulmonary fibrosis the presence of hiatus hernia is associated with disease progression and mortality Eur Respir J. 2019 May; 53(5). . View in PubMed

Influence of Idiopathic Pulmonary Fibrosis Progression on Healthcare Resource Use Pharmacoecon Open. 2019 Mar; 3(1):81-91. . View in PubMed

A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis Eur Respir J. 2019 Mar; 53(3). . View in PubMed

Gait speed and prognosis in patients with idiopathic pulmonary fibrosis: a prospective cohort study Eur Respir J. 2019 Feb; 53(2). . View in PubMed

Idiopathic Pulmonary Fibrosis: New and Emerging Treatment Options Drugs Aging. 2019 06; 36(6):485-492. . View in PubMed

Lung function outcomes in the INPULSIS® trials of nintedanib in idiopathic pulmonary fibrosis Respir Med. 2019 01; 146:42-48. . View in PubMed

Computed Tomographic Biomarkers in Idiopathic Pulmonary FibrosisThe Future of Quantitative Analysis. Am J Respir Crit Care Med. 2019 01 01; 199(1):12-21. . View in PubMed

Nintedanib for Systemic Sclerosis-Associated Interstitial Lung Disease N Engl J Med. 2019 06 27; 380(26):2518-2528. . View in PubMed

No relevant pharmacokinetic drug-drug interaction between nintedanib and pirfenidone Eur Respir J. 2019 Jan; 53(1). . View in PubMed

Could quality be the key in connective tissue disease-associated interstitial lung disease? Respirology. 2018 Jun 13.. View in PubMed

Incidence, Prevalence, and Survival of Patients with Idiopathic Pulmonary Fibrosis in the UK Adv Ther. 2018 May; 35(5):724-736. . View in PubMed

Effect of ambulatory oxygen on quality of life for patients with fibrotic lung disease (AmbOx): a prospective, open-label, mixed-method, crossover randomised controlled trial Lancet Respir Med. 2018 10; 6(10):759-770. . View in PubMed

Likelihood of pulmonary hypertension in patients with idiopathic pulmonary fibrosis and emphysema Respirology. 2018 06; 23(6):593-599. . View in PubMed

Phenotypic characteristics associated with slow gait speed in idiopathic pulmonary fibrosis Respirology. 2018 05; 23(5):498-506. . View in PubMed

Metformin Does Not Affect Clinically Relevant Outcomes in Patients with Idiopathic Pulmonary Fibrosis Respiration. 2018; 96(4):314-322. . View in PubMed

Investigating the effects of nintedanib on biomarkers of extracellular matrix turnover in patients with IPF: design of the randomised placebo-controlled INMARK®trial BMJ Open Respir Res. 2018; 5(1):e000325. . View in PubMed

Combination Therapy and the Start of a New Epoch for Idiopathic Pulmonary Fibrosis? Am J Respir Crit Care Med. 2018 02 01; 197(3):283-284.. View in PubMed

Identifying Barriers to Idiopathic Pulmonary Fibrosis Treatment: A Survey of Patient and Physician Views Respiration. 2018; 96(6):514-524. . View in PubMed

Nintedanib in patients with idiopathic pulmonary fibrosis and preserved lung volume Thorax. 2017 Apr; 72(4):340-346. . View in PubMed

An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study Lancet Respir Med. 2017 12; 5(12):946-955. . View in PubMed

A lesson in plasticity: a 74-year-old man with plastic bronchitis Thorax. 2017 11; 72(11):1055-1057. . View in PubMed

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study Lancet Respir Med. 2017 11; 5(11):869-880. . View in PubMed

Cough in fibrotic lung disease: An unresolved challenge Respirology. 2017 11; 22(8):1491-1492. . View in PubMed

A novel formulation of inhaled sodium cromoglicate (PA101) in idiopathic pulmonary fibrosis and chronic cough: a randomised, double-blind, proof-of-concept, phase 2 trial Lancet Respir Med. 2017 10; 5(10):806-815. . View in PubMed

Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: an international case-cohort study Eur Respir J. 2017 08; 50(2). . View in PubMed

Functional and prognostic effects when emphysema complicates idiopathic pulmonary fibrosis Eur Respir J. 2017 07; 50(1). . View in PubMed

Home spirometry for idiopathic pulmonary fibrosis: ready for prime time? Eur Respir J. 2017 07; 50(1).. View in PubMed

A Cost-Effectiveness Analysis of Nintedanib in Idiopathic Pulmonary Fibrosis in the UK Pharmacoeconomics. 2017 04; 35(4):479-491. . View in PubMed

Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis Thorax. 2017 02; 72(2):148-153. . View in PubMed

Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone Respiration. 2017; 93(6):415-423. . View in PubMed

Host-Microbial Interactions in Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2017 06 15; 195(12):1640-1650. . View in PubMed

Changes in the respiratory microbiome during acute exacerbations of idiopathic pulmonary fibrosis Respir Res. 2017 02 01; 18(1):29. . View in PubMed

Ambulatory oxygen in fibrotic lung disease (AmbOx): study protocol for a randomised controlled trial Trials. 2017 04 28; 18(1):201. . View in PubMed

Patient eligibility for anti-fibrotic therapy in idiopathic pulmonary fibrosis can be altered by use of different sets of reference values for calculation of FVC percent predicted Respir Med. 2016 11; 120:131-133. . View in PubMed

Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF Thorax. 2016 08; 71(8):701-11. . View in PubMed

Medicine and Me: a breath of fresh air for IPF Lancet Respir Med. 2016 08; 4(8):615-616. . View in PubMed

Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis Lancet Respir Med. 2016 05; 4(5):381-9. . View in PubMed

Daily Home Spirometry: An Effective Tool for Detecting Progression in Idiopathic Pulmonary Fibrosis Am J Respir Crit Care Med. 2016 10 15; 194(8):989-997. . View in PubMed

Fantasy or Reality? Am J Respir Crit Care Med. 2016 11 15; 194(10):1182-1184.. View in PubMed

Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia BMC Genet. 2016 06 07; 17(1):74. . View in PubMed

Acute Exacerbation of Idiopathic Pulmonary FibrosisAn International Working Group Report. Am J Respir Crit Care Med. 2016 08 01; 194(3):265-75. . View in PubMed

An Unexplored Realm in the Search for Fibrosis Therapies? Am J Respir Crit Care Med. 2015 Dec 15; 192(12):1407-9.. View in PubMed

Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique Adv Ther. 2015 Oct; 32(10):929-43. . View in PubMed

New guideline on treatment of idiopathic pulmonary fibrosis Lancet Respir Med. 2015 Sep; 3(9):e31-e32. . View in PubMed

Personalized medicine in idiopathic pulmonary fibrosis: facts and promises Curr Opin Pulm Med. 2015 Sep; 21(5):470-8. . View in PubMed

Nintedanib in idiopathic pulmonary fibrosis Drugs Today (Barc). 2015 Jun; 51(6):345-56. . View in PubMed

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study Lancet Respir Med. 2015 Jun; 3(6):462-72. . View in PubMed

Long-term clinical and real-world experience with pirfenidone in the treatment of idiopathic pulmonary fibrosis Eur Respir Rev. 2015 Mar; 24(135):58-64. . View in PubMed

Pharmacological Treatment of Idiopathic Pulmonary Fibrosis: Current Approaches, Unsolved Issues, and Future Perspectives Biomed Res Int. 2015; 2015:329481. . View in PubMed

Combination therapy: the future of management for idiopathic pulmonary fibrosis? Lancet Respir Med. 2014 Nov; 2(11):933-942.. View in PubMed

Can we do better? Respirology. 2014 Nov; 19(8):1095-6.. View in PubMed

Case-based discussion from the Royal Devon and Exeter NHS Foundation Trust: a painful paradox Thorax. 2014 Aug; 69(8):779-81. . View in PubMed

Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia Am J Respir Crit Care Med. 2014 Jul 15; 190(2):208-17. . View in PubMed

Disease stratification in idiopathic pulmonary fibrosis: the dawn of a new era? Eur Respir J. 2014 May; 43(5):1233-6.. View in PubMed

Pirfenidone in idiopathic pulmonary fibrosis: expert panel discussion on the management of drug-related adverse events Adv Ther. 2014 Apr; 31(4):375-91. . View in PubMed

Immunosuppression for connective tissue disease-related pulmonary disease Semin Respir Crit Care Med. 2014 Apr; 35(2):265-73. . View in PubMed

Cyclical caspofungin for chronic pulmonary aspergillosis in sarcoidosis Thorax. 2014 Mar; 69(3):287-8. . View in PubMed

Areas of normal pulmonary parenchyma on HRCT exhibit increased FDG PET signal in IPF patients Eur J Nucl Med Mol Imaging. 2014 Feb; 41(2):337-42. . View in PubMed

An integrated clinicoradiological staging system for pulmonary sarcoidosis: a case-cohort study Lancet Respir Med. 2014 Feb; 2(2):123-30. . View in PubMed

Beyond the diagnosis of idiopathic pulmonary fibrosis; the growing role of systems biology and stratified medicine Curr Opin Pulm Med. 2013 Sep; 19(5):460-5. . View in PubMed

Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease Respir Res. 2013 Aug 02; 14:80. . View in PubMed

Novel use of rituximab in hypersensitivity pneumonitis refractory to conventional treatment Thorax. 2013 Aug; 68(8):780-1. . View in PubMed

Mapping the future for pulmonary fibrosis: report from the 17th International Colloquium on Lung and Airway Fibrosis Eur Respir J. 2013 Jul; 42(1):230-8. . View in PubMed

Exercise-induced haemoptysis: a thoroughbred cause? Thorax. 2013 Jun; 68(6):599-600.. View in PubMed

Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis Thorax. 2013 May; 68(5):436-41. . View in PubMed

Obliterative bronchiolitis in fibreglass workers: a new occupational disease? Occup Environ Med. 2013 May; 70(5):357-9.. View in PubMed

A clinical approach to diffuse parenchymal lung disease Immunol Allergy Clin North Am. 2012 Nov; 32(4):453-72. . View in PubMed

Drug-/radiation-induced interstitial lung disease in the United Kingdom general population: incidence, all-cause mortality and characteristics at diagnosis Respirology. 2012 Jul; 17(5):861-8. . View in PubMed

Elevated nocturnal desaturation index predicts mortality in interstitial lung disease Sarcoidosis Vasc Diffuse Lung Dis. 2012 Mar; 29(1):41-50. . View in PubMed

18F-Fluorodeoxyglucose positron emission tomography pulmonary imaging in idiopathic pulmonary fibrosis is reproducible: implications for future clinical trials Eur J Nucl Med Mol Imaging. 2012 Mar; 39(3):521-8. . View in PubMed

Idiopathic pulmonary fibrosis: pathobiology of novel approaches to treatment Clin Chest Med. 2012 Mar; 33(1):69-83. . View in PubMed

In search of the fibrotic epithelial cell: opportunities for a collaborative network Thorax. 2012 Feb; 67(2):179-82. . View in PubMed

Diffuse cystic lung disease of unexplained cause with coexistent small airway disease: a possible causal relationship? Am J Surg Pathol. 2012 Feb; 36(2):228-34.. View in PubMed

Current and novel drug therapies for idiopathic pulmonary fibrosis Drug Des Devel Ther. 2012; 6:261-72. . View in PubMed

Ambulatory oxygen in interstitial lung disease Eur Respir J. 2011 Oct; 38(4):987-90. . View in PubMed

Idiopathic pulmonary fibrosis-related pulmonary hypertension; an exercising diagnosis? Respirology. 2011 Apr; 16(3):381-3.. View in PubMed

If it was good enough for Aristotle. . . . . Thorax. 2011 Mar; 66(3):183-84. . View in PubMed

Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis Am J Respir Crit Care Med. 2010 Jul 01; 182(1):73-82. . View in PubMed

Pirfenidone in idiopathic pulmonary fibrosis Drugs Today (Barc). 2010 Jul; 46(7):473-82. . View in PubMed

Lost in translation; from animal models of pulmonary fibrosis to human disease Respirology. 2009 Sep; 14(7):915-6. . View in PubMed

Optimal treatment for idiopathic pulmonary fibrosis Thorax. 2008 Dec; 63(12):1120-1; author reply 1121. . View in PubMed

Interstitial lung disease in systemic sclerosis: a simple staging system Am J Respir Crit Care Med. 2008 Jun 01; 177(11):1248-54. . View in PubMed

Idiopathic pulmonary fibrosis: multiple causes and multiple mechanisms? Eur Respir J. 2007 Nov; 30(5):835-9.. View in PubMed

CT findings of varicella pneumonia after lung transplantation AJR Am J Roentgenol. 2007 Jun; 188(6):W557-9. . View in PubMed

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