Uri Elkayam, MD

Clinical Professor of Medicine (Part-Time)

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Overview

Dr. Uri Elkayam is a professor of Medicine and Obstetrics and Gynecology and director of the maternal cardiology program at the university of Southern California in Los Angeles. Dr. Elkayam has been a member of the faculty of the division of cardiology since 1981 and his previous positions included chief of cardiology USC university hospital and director of the heart failure program. He is a past member of the executive council of the Heart Failure Society of America.

Dr Elkayam research and clinical interests are congestive heart failure, heart disease and pregnancy, valvular heart disease, cardiomyopathies, and cardiovascular pharmacology. He has been involved in more than 100 self-initiated, NIH and industry funded research projects and has served in a leading position in numerous national and international multicenter studies.

He is an associate editor of the journal JACC Advances and an editorial consultant for the journal JACC heart failure. Dr. Elkayam is the author or co-author of over 250 publications and over 90 book chapters and the editor of 4 editions of the textbook “Cardiac Problems in Pregnancy”.

He has been the director of the annual Los Angeles heart failure symposium for the last 27 years, the founder and chairman of the International Congress on Cardiac Problems in Pregnancy and the director of an annual national symposium on Cardio Obstetrics.

Dr. Elkayam was the recipient of the 2021 American College of Cardiology Bernadine Healy Leadership in Women’s Cardiovascular Disease Distinguished Award.

Awards

  • American College of Cardiology: Bernadine Healy Leadership in Women’s Cardiovascular Disease Distinguished Award, 2021
  • International Academy of Cardiology: Distinguished Fellowship Award- Cardiology, 2007
  • 8th World Congress on Heart Failure : Melvin L. Marcus Memorial Award for Distinguished Contribution as a Gifted Teacher, 2002
  • Department of Maternal- Fetal Medicine, USC Women’s & Children’s Hospital : Award for Education of Residents and Fellows, 2002

Publications

  • Successful Pregnancy After Left Ventricular Assist Device Explantation for Myocardial Recovery ASAIO J. 2024 Feb 01. . View in PubMed
  • Peripartum HFpEF: Identification of a Novel Phenotype and the Need for Cardio-Obstetrics Management JACC Adv. 2024 Feb; 3(2):100799. . View in PubMed
  • An Updated Review on the Role of Non-dihydropyridine Calcium Channel Blockers and Beta-blockers in Atrial Fibrillation and Acute Decompensated Heart Failure: Evidence and Gaps Cardiovasc Drugs Ther. 2023 Dec; 37(6):1205-1223. . View in PubMed
  • Safety of Subsequent Pregnancy After Recovery From Peripartum Cardiomyopathy J Am Coll Cardiol. 2023 07 04; 82(1):27-29. . View in PubMed
  • Contemporary outcome of subsequent pregnancies in patients with previous peripartum cardiomyopathy ESC Heart Fail. 2022 Sep 20. . View in PubMed
  • Catheter-Based Interventions for the Management of Valvular Heart Disease During Pregnancy JACC Adv. 2022 Jun; 1(2):100022. . View in PubMed
  • Society for Maternal-Fetal Medicine Consult Series #61: Anticoagulation in pregnant patients with cardiac disease Am J Obstet Gynecol. 2022 08; 227(2):B28-B43. . View in PubMed
  • Hypertensive disorders of pregnant women with heart disease: the ESC EORP ROPAC Registry Eur Heart J. 2022 10 11; 43(38):3749-3761. . View in PubMed
  • Outcome of Pregnancy in Women With D-Transposition of the Great Arteries: A Systematic Review J Am Heart Assoc. 2022 12 06; 11(23):e026862. . View in PubMed
  • Heart Failure Subtypes and Cardiomyopathies in Women Circ Res. 2022 02 18; 130(4):436-454. . View in PubMed
  • Proinflammatory TH17 cytokine activation, disease severity and outcomes in peripartum cardiomyopathy Int J Cardiol. 2021 Sep 15; 339:93-98. . View in PubMed
  • Cardiomyopathy and Pregnancy: Considerations for Women With Severely Reduced Left Ventricular Dysfunction Can J Cardiol. 2021 12; 37(12):2067-2075. . View in PubMed
  • The Hidden Cost of Meth: Appraising the Socioeconomic Burden of Methamphetamine-Associated Cardiomyopathy Circ Cardiovasc Qual Outcomes. 2021 07; 14(7):e008214. . View in PubMed
  • Acute pulmonary pressure change after transition to sacubitril/valsartan in patients with heart failure reduced ejection fraction ESC Heart Fail. 2021 04; 8(2):1706-1710. . View in PubMed
  • Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy Circulation. 2021 05 11; 143(19):1852-1862. . View in PubMed
  • Changing Incidence and Mechanism of Pregnancy-Associated Myocardial Infarction in the State of California J Am Heart Assoc. 2021 11 02; 10(21):e021056. . View in PubMed
  • Characteristics of Methamphetamine-associated Cardiomyopathy and the Impact of Methamphetamine Use on Cardiac Dysfunction Am J Cardiol. 2021 09 01; 154:86-91. . View in PubMed
  • Pregnancy in women with rheumatic valve disease: how to improve the outcome? Heart. 2020 09; 106(18):1374-1375.. View in PubMed
  • Tolvaptan vsfurosemide-based diuretic regimens in patients hospitalized for heart failure with hyponatremia (AQUA-AHF). ESC Heart Fail. 2020 08; 7(4):1927-1934. . View in PubMed
  • Clinical Characteristics and Management of Methamphetamine-Associated Cardiomyopathy: State-of-the-Art Review J Am Heart Assoc. 2020 06 02; 9(11):e016704. . View in PubMed
  • Peripartum cardiomyopathy: one disease with many faces Eur Heart J. 2020 10 14; 41(39):3798-3800. . View in PubMed
  • Acute Postpartum Heart Failure With Preserved Systolic Function JACC Case Rep. 2020 Jan; 2(1):82-85. . View in PubMed
  • Peripartum Cardiomyopathy: JACC State-of-the-Art Review J Am Coll Cardiol. 2020 01 21; 75(2):207-221. . View in PubMed
  • Use of Impella heart pump for management of women with peripartum cardiogenic shock Clin Cardiol. 2019 Oct; 42(10):974-981. . View in PubMed
  • Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy JACC Basic Transl Sci. 2019 Jun; 4(3):291-300. . View in PubMed
  • Electrocardiographic findings in peripartum cardiomyopathy Clin Cardiol. 2019 May; 42(5):524-529. . View in PubMed
  • Pregnancy outcomes in women with cardiovascular disease: evolving trends over 10 years in the ESC Registry Of Pregnancy And Cardiac disease (ROPAC) Eur Heart J. 2019 12 14; 40(47):3848-3855. . View in PubMed
  • Association of admission vsnadir serum albumin concentration with short-term treatment outcomes in patients with acute heart failure. J Int Med Res. 2018 Sep; 46(9):3665-3674. . View in PubMed
  • Peripartum cardiomyopathy: approach to management Curr Opin Cardiol. 2018 05; 33(3):347-353. . View in PubMed
  • Pregnancy-Associated Coronary Artery Dissection: A Therapeutic Dilemma J Am Coll Cardiol. 2018 01 30; 71(4):469-470. . View in PubMed
  • Imbalanced Angiogenesis in Peripartum Cardiomyopathy (PPCM) Circ J. 2018 09 25; 82(10):2689. . View in PubMed
  • How to Predict Pregnancy Risk in an Individual Woman With Heart Disease J Am Coll Cardiol. 2018 05 29; 71(21):2431-2433. . View in PubMed
  • Pregnancy and Marfan syndrome Ann Cardiothorac Surg. 2017 Nov; 6(6):642-653. . View in PubMed
  • Myocardial Damage Detected by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Uncommon in Peripartum Cardiomyopathy J Am Heart Assoc. 2017 Apr 03; 6(4). . View in PubMed
  • Heart Failure-Induced Brain Injury J Am Coll Cardiol. 2017 Mar 28; 69(12):1609-1616. . View in PubMed
  • Pregnancy and the Risk of Spontaneous Coronary Artery Dissection: An Analysis of 120 Contemporary Cases Circ Cardiovasc Interv. 2017 Mar; 10(3). . View in PubMed
  • Can I get pregnant again? Eur J Heart Fail. 2017 12; 19(12):1729-1731.. View in PubMed
  • Peripartum cardiomyopathy for the clinician: the known and the unknown Eur J Heart Fail. 2017 09; 19(9):1142-1144. . View in PubMed
  • Angiotensin Receptor-Neprilysin Inhibition J Cardiovasc Pharmacol Ther. 2017 07; 22(4):356-364. . View in PubMed
  • Anticoagulation Therapy for Pregnant Women With Mechanical Prosthetic Heart Valves: How to Improve Safety? J Am Coll Cardiol. 2017 06 06; 69(22):2692-2695.. View in PubMed
  • Response by Arany and Elkayam to Letter Regarding Article, “Peripartum Cardiomyopathy” Circulation. 2016 Aug 16; 134(7):e83-4. . View in PubMed
  • High-Risk Cardiac Disease in Pregnancy: Part II J Am Coll Cardiol. 2016 Aug 02; 68(5):502-516. . View in PubMed
  • Relaxin for the Treatment of Acute Decompensated Heart Failure: Pharmacology, Mechanisms of Action, and Clinical Evidence Cardiol Rev. 2016 Jul-Aug; 24(4):194-204. . View in PubMed
  • Peripartum Cardiomyopathy Circulation. 2016 Apr 05; 133(14):1397-409. . View in PubMed
  • GNB3 C825T Polymorphism and Myocardial Recovery in Peripartum Cardiomyopathy: Results of the Multicenter Investigations of Pregnancy-Associated Cardiomyopathy Study Circ Heart Fail. 2016 Mar; 9(3):e002683. . View in PubMed
  • Reply: Comparison of the American PPCM Registry Data With International Registries J Am Coll Cardiol. 2016 Feb 16; 67(6):734-735. . View in PubMed
  • Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies N Engl J Med. 2016 Jan 21; 374(3):233-41. . View in PubMed
  • Echocardiography in Pregnancy: Part 2 Curr Cardiol Rep. 2016 09; 18(9):90. . View in PubMed
  • Echocardiography in Pregnancy: Part 1 Curr Cardiol Rep. 2016 09; 18(9):92. . View in PubMed
  • The Search for a Crystal Ball to Predict Early Recovery From Peripartum Cardiomyopathy? JACC Heart Fail. 2016 05; 4(5):389-91.. View in PubMed
  • J Am Coll Cardiol. 2016 12 20; 68(24):2717-2718. . View in PubMed
  • High-Risk Cardiac Disease in Pregnancy: Part I J Am Coll Cardiol. 2016 07 26; 68(4):396-410. . View in PubMed
  • Clinical Outcomes for Peripartum Cardiomyopathy in North America: Results of the IPAC Study (Investigations of Pregnancy-Associated Cardiomyopathy) J Am Coll Cardiol. 2015 Aug 25; 66(8):905-14. . View in PubMed
  • “Of mice and (wo)men”: The need to confirm results of animal experimentations with solid clinical data Trends Cardiovasc Med. 2015 Aug; 25(6):505-7. . View in PubMed
  • Cardiorenal interactions in acute decompensated heart failure: contemporary concepts facing emerging controversies J Card Fail. 2014 Dec; 20(12):1004-11. . View in PubMed
  • Cardiac medication during pregnancy, data from the ROPAC Int J Cardiol. 2014 Nov 15; 177(1):124-8. . View in PubMed
  • Risk of subsequent pregnancy in women with a history of peripartum cardiomyopathy J Am Coll Cardiol. 2014 Oct 14; 64(15):1629-36. . View in PubMed
  • Monitoring of anti-Xa in pregnant patients with mechanical prosthetic valves receiving low-molecular-weight heparin: peak or trough levels? J Cardiovasc Pharmacol Ther. 2014 Sep; 19(5):451-6.. View in PubMed
  • Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial Am J Cardiol. 2014 Jul 01; 114(1):151-9. . View in PubMed
  • EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM Eur J Heart Fail. 2014 May; 16(5):583-91. . View in PubMed
  • Pregnancy-associated acute myocardial infarction: a review of contemporary experience in 150 cases between 2006 and 2011 Circulation. 2014 Apr 22; 129(16):1695-702. . View in PubMed
  • Some more on preventing congenital heart block Autoimmun Rev. 2014 Jan; 13(1):73-4. . View in PubMed
  • Association of hyponatremia to diuretic response and incidence of increased serum creatinine levels in hospitalized patients with acute decompensated heart failure Cardiology. 2014; 128(4):333-42. . View in PubMed
  • Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials Autoimmun Rev. 2013 Sep; 12(11):1039-45. . View in PubMed
  • Effect of amlodipine on the survival of patients with severe chronic heart failure due to a nonischemic cardiomyopathy: results of the PRAISE-2 study (prospective randomized amlodipine survival evaluation 2) JACC Heart Fail. 2013 Aug; 1(4):308-314. . View in PubMed
  • Mechanical heart valve thrombosis in pregnancy J Heart Valve Dis. 2013 Jul; 22(4):603-6. . View in PubMed
  • Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure J Cardiovasc Pharmacol Ther. 2013 Jul; 18(4):345-53. . View in PubMed
  • Differences in clinical profile of African-American women with peripartum cardiomyopathy in the United States J Card Fail. 2013 Apr; 19(4):214-8. . View in PubMed
  • Cardiovascular imaging of the pregnant patient AJR Am J Roentgenol. 2013 Mar; 200(3):515-21. . View in PubMed
  • Clinical experience with low-dose continuous infusion of furosemide in acute heart failure: assessment of efficacy and safety J Cardiovasc Pharmacol Ther. 2012 Dec; 17(4):373-81. . View in PubMed
  • Anticoagulation in pregnancy Cardiol Clin. 2012 Aug; 30(3):395-405. . View in PubMed
  • Cardiovascular drugs in pregnancy Cardiol Clin. 2012 Aug; 30(3):463-91. . View in PubMed
  • Physiologic changes during normal pregnancy and delivery Cardiol Clin. 2012 Aug; 30(3):317-29. . View in PubMed
  • Peripartum cardiomyopathy Cardiol Clin. 2012 Aug; 30(3):435-40. . View in PubMed
  • Cardiovascular disease in pregnancyPreface. Cardiol Clin. 2012 Aug; 30(3):xi-xii. . View in PubMed
  • Serial echocardiographic assessment of the human heart in normal pregnancy Circ Cardiovasc Imaging. 2012 May 01; 5(3):283-5. . View in PubMed
  • The search for a safe and effective anticoagulation regimen in pregnant women with mechanical prosthetic heart valves J Am Coll Cardiol. 2012 Mar 20; 59(12):1116-8. . View in PubMed
  • Comparative effects of nesiritide and nitroglycerin on renal function, and incidence of renal injury by traditional and RIFLE criteria in acute heart failure J Cardiovasc Pharmacol Ther. 2012 Mar; 17(1):79-85. . View in PubMed
  • Clinical characteristics of peripartum cardiomyopathy in the United States: diagnosis, prognosis, and management J Am Coll Cardiol. 2011 Aug 09; 58(7):659-70. . View in PubMed
  • Evaluation of the clinical relevance of baseline left ventricular ejection fraction as a predictor of recovery or persistence of severe dysfunction in women in the United States with peripartum cardiomyopathy J Card Fail. 2011 May; 17(5):426-30. . View in PubMed
  • Rationale and design of the treatment of hyponatremia based on lixivaptan in NYHA class III/IV cardiac patient evaluation (THE BALANCE) study Clin Transl Sci. 2010 Oct; 3(5):249-53. . View in PubMed
  • Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy Eur J Heart Fail. 2010 Aug; 12(8):767-78. . View in PubMed
  • Comparison of pioglitazone vs glyburide in early heart failure: insights from a randomized controlled study of patients with type 2 diabetes and mild cardiac disease Congest Heart Fail. 2010 May-Jun; 16(3):111-7. . View in PubMed
  • Bromocriptine for the treatment of peripartum cardiomyopathy Circulation. 2010 Apr 06; 121(13):1463-4. . View in PubMed
  • Venous thromboembolism in hospitalized patients with heart failure: incidence, prognosis, and prevention Circ Heart Fail. 2010 Jan; 3(1):165-73. . View in PubMed
  • Cardiomyopathy: the importance of recognizing the uncommon diagnosis Prog Cardiovasc Dis. 2010 Jan-Feb; 52(4):262-3. . View in PubMed
  • Favorable outcome of pregnancy with an elective use of epoprostenol and sildenafil in women with severe pulmonary hypertension Cardiology. 2010; 115(3):205-8. . View in PubMed
  • Left ventricular noncompaction Prog Cardiovasc Dis. 2010 Jan-Feb; 52(4):264-73. . View in PubMed
  • Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials Eur Heart J. 2009 Dec; 30(24):3015-26. . View in PubMed
  • A low-literacy medication education tool for safety-net hospital patients Am J Prev Med. 2009 Dec; 37(6 Suppl 1):S209-16. . View in PubMed
  • Pregnancy in Marfan syndrome: maternal and fetal risk and recommendations for patient assessment and management Cardiol Rev. 2009 Nov-Dec; 17(6):253-62. . View in PubMed
  • Clinical profile and predictors of complications in peripartum cardiomyopathy J Card Fail. 2009 Oct; 15(8):645-50. . View in PubMed
  • Longitudinal changes in the B-type natriuretic peptide levels in normal pregnancy and postpartum Clin Cardiol. 2009 Aug; 32(8):E60-2. . View in PubMed
  • Beta-blockers in the treatment of aortic regurgitation a new opportunity? J Am Coll Cardiol. 2009 Jul 28; 54(5):458-9.. View in PubMed
  • Reduction in mitral regurgitation during therapy guided by measured filling pressures in the ESCAPE trial Circ Heart Fail. 2009 May; 2(3):181-8. . View in PubMed
  • Impact of acute serum creatinine elevation in patients treated with nesiritide Clin Cardiol. 2009 Apr; 32(4):215-9. . View in PubMed
  • Peripartum cardiomyopathy, an autoimmune manifestation of allograft rejection? Autoimmun Rev. 2009 Mar; 8(5):384-7.. View in PubMed
  • Cardiovascular problems in pregnant women with marfan syndrome Circulation. 2009 Feb 03; 119(4):619-23. . View in PubMed
  • Assessment of renal hemodynamic effects of nesiritide in patients with heart failure using intravascular Doppler and quantitative angiography JACC Cardiovasc Imaging. 2008 Nov; 1(6):765-71. . View in PubMed
  • Cheyne-Stokes respiration and cardiac hemodynamics in heart failure Catheter Cardiovasc Interv. 2008 Oct 01; 72(4):581-5. . View in PubMed
  • Efficacy and safety of the vasopressin V1A/V2-receptor antagonist conivaptan in acute decompensated heart failure: a dose-ranging pilot study J Card Fail. 2008 Oct; 14(8):641-7. . View in PubMed
  • Pioglitazone and heart failure: results from a controlled study in patients with type 2 diabetes mellitus and systolic dysfunction J Card Fail. 2008 Aug; 14(6):445-52. . View in PubMed
  • Acute myocardial infarction associated with pregnancy J Am Coll Cardiol. 2008 Jul 15; 52(3):171-80. . View in PubMed
  • Renal Vasodilatory Action of Dopamine in Patients With Heart Failure: Magnitude of Effect and Site of Action Circulation. 2008 Jan 15; 117(2):200-205. . View in PubMed
  • Vasodilators in the management of acute heart failure Crit Care Med. 2008 Jan; 36(1 Suppl):S95-105. . View in PubMed
  • Effect of pulmonary stenosis on pregnancy outcomes–a case-control study Am Heart J. 2007 Nov; 154(5):852-4. . View in PubMed
  • The challenge of correcting volume overload in hospitalized patients with decompensated heart failure J Am Coll Cardiol. 2007 Feb 13; 49(6):684-6. . View in PubMed
  • Use and impact of inotropes and vasodilator therapy in hospitalized patients with severe heart failure Am Heart J. 2007 Jan; 153(1):98-104. . View in PubMed
  • Comparison of 60-day mortality in hospitalized heart failure patients with versus without hypothermia Am J Cardiol. 2006 Dec 01; 98(11):1485-8. . View in PubMed
  • Variable response of conductance and resistance coronary arteries to endothelial stimulation in patients with heart failure due to nonischemic dilated cardiomyopathy J Cardiovasc Pharmacol Ther. 2006 Sep; 11(3):197-202. . View in PubMed
  • Peripartum cardiomyopathy Lancet. 2006 Aug 19; 368(9536):687-93. . View in PubMed
  • Safety of exercise testing in the chest pain unit: 31-mm ST elevation in variant angina J Electrocardiol. 2006 Jul; 39(3):309. . View in PubMed
  • Effects of nitrates and hydralazine in heart failure: clinical evidence before the african american heart failure trial Am J Cardiol. 2005 Oct 10; 96(7B):37i-43i. . View in PubMed
  • Valvular heart disease and pregnancy: part II: prosthetic valves J Am Coll Cardiol. 2005 Aug 02; 46(3):403-10. . View in PubMed
  • Left atrial thrombosis in pregnant women with mitral stenosis and sinus rhythm Am J Obstet Gynecol. 2005 Aug; 193(2):501-4. . View in PubMed
  • Valvular heart disease and pregnancy part I: native valves J Am Coll Cardiol. 2005 Jul 19; 46(2):223-30. . View in PubMed
  • The clinical challenge of bridging anticoagulation with low-molecular-weight heparin in patients with mechanical prosthetic heart valves: an evidence-based comparative review focusing on anticoagulation options in pregnant and nonpregnant patients Am Heart J. 2005 Jul; 150(1):27-34. . View in PubMed
  • Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentation Circulation. 2005 Apr 26; 111(16):2050-5. . View in PubMed
  • Letter regarding article by Wang et al, “nesiritide does not improve renal function in patients with chronic heart failure and worsening serum creatinine” Circulation. 2005 Apr 12; 111(14):e182-3; author reply e182-3. . View in PubMed
  • J Am Coll Cardiol. 2005 Jan 18; 45(2):252-9. . View in PubMed
  • Survey of the use of organic nitrates for the treatment of chronic congestive heart failure in the United States Am J Cardiol. 2004 Dec 01; 94(11):1465-8. . View in PubMed
  • Intravenous nitroglycerin in the treatment of decompensated heart failure: potential benefits and limitations J Cardiovasc Pharmacol Ther. 2004 Dec; 9(4):227-41. . View in PubMed
  • Effect of elevated admission serum creatinine and its worsening on outcome in hospitalized patients with decompensated heart failure Am J Cardiol. 2004 Oct 01; 94(7):957-60. . View in PubMed
  • Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation Cardiol Rev. 2004 Sep-Oct; 12(5):240-61. . View in PubMed
  • Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation Cardiol Rev. 2004 Jul-Aug; 12(4):201-21. . View in PubMed
  • Anticoagulation in pregnant women with prosthetic heart valves J Cardiovasc Pharmacol Ther. 2004 Jun; 9(2):107-15. . View in PubMed
  • Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial JAMA. 2004 Apr 28; 291(16):1963-71. . View in PubMed
  • Comparison of effects on left ventricular filling pressure of intravenous nesiritide and high-dose nitroglycerin in patients with decompensated heart failure Am J Cardiol. 2004 Jan 15; 93(2):237-40. . View in PubMed
  • Evaluation of myocardial blood flow reserve in patients with chronic congestive heart failure due to idiopathic dilated cardiomyopathy Am J Cardiol. 2003 Nov 15; 92(10):1246-9. . View in PubMed
  • Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure J Am Coll Cardiol. 2003 Jul 02; 42(1):140-7. . View in PubMed
  • Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure Am Heart J. 2003 Feb; 145(2 Suppl):S51-4. . View in PubMed
  • Effect of nesiritide (B-type natriuretic peptide) and dobutamine on ventricular arrhythmias in the treatment of patients with acutely decompensated congestive heart failure: the PRECEDENT study Am Heart J. 2002 Dec; 144(6):1102-8. . View in PubMed
  • Nesiritide: a new drug for the treatment of decompensated heart failure J Cardiovasc Pharmacol Ther. 2002 Jul; 7(3):181-94. . View in PubMed
  • Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure J Am Coll Cardiol. 2002 Mar 06; 39(5):798-803. . View in PubMed
  • Impaired endothelium-mediated vasodilation in heart failure: clinical evidence and the potential for therapy J Card Fail. 2002 Feb; 8(1):15-20. . View in PubMed
  • Endothelial function in patients with chronic heart failure J Cardiovasc Pharmacol. 2001 Nov; 38 Suppl 2:S47-8. . View in PubMed
  • Maternal and fetal outcomes of subsequent pregnancies in women with peripartum cardiomyopathy N Engl J Med. 2001 May 24; 344(21):1567-71. . View in PubMed
  • The effect of valvular heart disease on maternal and fetal outcome of pregnancy J Am Coll Cardiol. 2001 Mar 01; 37(3):893-9. . View in PubMed
  • Unstable angina during pregnancy in two patients with premature coronary atherosclerosis and aortic stenosis in association with familial hypercholesterolemia Am J Obstet Gynecol. 2000 May; 182(5):1152-5. . View in PubMed
  • Double-blind, placebo-controlled study to evaluate the effect of organic nitrates in patients with chronic heart failure treated with angiotensin-converting enzyme inhibition Circulation. 1999 May 25; 99(20):2652-7. . View in PubMed
  • Favorable response of Eisenmenger syndrome to inhaled nitric oxide during pregnancy Am J Obstet Gynecol. 1999 Jan; 180(1 Pt 1):64-7. . View in PubMed
  • The role of organic nitrates in the treatment of heart failure Prog Cardiovasc Dis. 1999 Jan-Feb; 41(4):255-64. . View in PubMed
  • Renal circulatory effects of adenosine in patients with chronic heart failure J Am Coll Cardiol. 1998 Jul; 32(1):211-5. . View in PubMed
  • Pharmacokinetic and pharmacodynamic evaluation of atenolol during and after pregnancy Pharmacotherapy. 1998 Jul-Aug; 18(4):840-6. . View in PubMed
  • Calcium channel blockers in heart failure Cardiology. 1998; 89 Suppl 1:38-46. . View in PubMed
  • Incidence of arrhythmias in normal pregnancy and relation to palpitations, dizziness, and syncope Am J Cardiol. 1997 Apr 15; 79(8):1061-4. . View in PubMed
  • Renal vasodilatory effect of endothelial stimulation in patients with chronic congestive heart failure J Am Coll Cardiol. 1996 Jul; 28(1):176-82. . View in PubMed
  • Anticoagulation in pregnant women with prosthetic heart valves: a double jeopardy J Am Coll Cardiol. 1996 Jun; 27(7):1704-6. . View in PubMed
  • Nitrates in the treatment of congestive heart failure Am J Cardiol. 1996 May 30; 77(13):41C-51C. . View in PubMed
  • Prevention of nitrate tolerance with concomitant administration of hydralazine Can J Cardiol. 1996 May; 12 Suppl C:17C-21C. . View in PubMed
  • Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure J Am Coll Cardiol. 1995 Dec; 26(7):1575-80. . View in PubMed
  • Escalating nitrate dose overcomes early attenuation of hemodynamic effect caused by nitrate tolerance in patients with heart failure Am Heart J. 1995 Oct; 130(4):798-805. . View in PubMed
  • Cardiovascular problems in pregnant women with the Marfan syndrome Ann Intern Med. 1995 Jul 15; 123(2):117-22. . View in PubMed
  • Adenosine therapy for supraventricular tachycardia during pregnancy Am J Cardiol. 1995 Mar 01; 75(7):521-3. . View in PubMed
  • Cardiac arrhythmia after infusion of cryopreserved stem cells Bone Marrow Transplant. 1994 Sep; 14(3):363-7. . View in PubMed
  • Potentiation of isosorbide dinitrate effects with N-acetylcysteine in patients with chronic heart failure Circulation. 1994 Jun; 89(6):2595-600. . View in PubMed
  • Risks of angiotensin-converting enzyme inhibition during pregnancy: experimental and clinical evidence, potential mechanisms, and recommendations for use Am J Med. 1994 May; 96(5):451-6. . View in PubMed
  • Nitrates in heart failure Cardiol Clin. 1994 Feb; 12(1):73-85. . View in PubMed
  • Plasma cyclic guanosine monophosphate in chronic heart failure: hemodynamic and neurohormonal correlations and response to nitrate therapy Clin Pharmacol Ther. 1993 Dec; 54(6):638-44. . View in PubMed
  • Calcium channel blockers in heart failure J Am Coll Cardiol. 1993 Oct; 22(4 Suppl A):139A-144A. . View in PubMed
  • A randomized comparison between the hemodynamic effects of hydralazine and nitroglycerin alone and in combination at rest and during isometric exercise in patients with chronic mitral regurgitation Am Heart J. 1993 Jan; 125(1):155-63. . View in PubMed
  • Possible mechanisms of nitrate tolerance Am J Cardiol. 1992 Nov 27; 70(17):49G-53G; discussion 53G-54G. . View in PubMed
  • Persistent hemodynamic improvement with short-term nitrate therapy in patients with chronic congestive heart failure already treated with captopril Am J Cardiol. 1992 Nov 15; 70(15):1310-4. . View in PubMed
  • Nitrate resistance and tolerance: potential limitations in the treatment of congestive heart failure Am J Cardiol. 1992 Sep 24; 70(8):98B-104B. . View in PubMed
  • WPW syndrome during pregnancy: increased incidence of supraventricular arrhythmias Am Heart J. 1992 Mar; 123(3):796-8. . View in PubMed
  • Randomized study to evaluate the relation between oral isosorbide dinitrate dosing interval and the development of early tolerance to its effect on left ventricular filling pressure in patients with chronic heart failure Circulation. 1991 Nov; 84(5):2040-8. . View in PubMed
  • Fetal and neonatal adverse effects profile of amiodarone treatment during pregnancy Am Heart J. 1991 Oct; 122(4 Pt 1):1162-6. . View in PubMed
  • Tolerance to organic nitrates: evidence, mechanisms, clinical relevance, and strategies for prevention Ann Intern Med. 1991 Apr 15; 114(8):667-77. . View in PubMed
  • A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure Circulation. 1990 Dec; 82(6):1954-61. . View in PubMed
  • Can prognosis be altered by treating LV dysfunction? Clin Cardiol. 1989 Jul; 12(7 Suppl 3):III58-64.. View in PubMed
  • Central and renal hemodynamic effects of a new agonist at peripheral dopamine- and beta-2 adrenoreceptors (dopexamine) in patients with heart failure Am Heart J. 1989 Mar; 117(3):607-14. . View in PubMed
  • Resistance to isosorbide dinitrate in patients with severe chronic heart failure: incidence and attempt at hemodynamic prediction J Am Coll Cardiol. 1988 Oct; 12(4):1023-8. . View in PubMed
  • Electrophysiologic effects of intravenous magnesium in patients with normal conduction systems and no clinical evidence of significant cardiac disease Am Heart J. 1988 Feb; 115(2):367-73. . View in PubMed
  • Cardiovascular drugs in pregnancy Cardiol Clin. 1987 Nov; 5(4):651-74. . View in PubMed
  • Hemodynamic and volumetric effects of venodilation with nitroglycerin in chronic mitral regurgitation Am J Cardiol. 1987 Nov 01; 60(13):1106-11. . View in PubMed