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Vadym Buncha

Postdoctoral Scholar - Research Associate

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Email [email protected]
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Publications

  • Pyridoxine supplementation amelioratesSGPL1 R222Q variant sphingosine phosphate lyase insufficiency syndrome in mice. J Clin Invest. 2026 Sep 24.. View in PubMed
  • Upregulated Renal Mineralocorticoid Receptor and 11β-Hydroxysteroid Dehydrogenase Type 2 Are Associated with K+ Retention During MR Antagonism in Female Spontaneously Hypertensive Rats. Int J Mol Sci. 2026 Aug 02; 27(15).. View in PubMed
  • Pyridoxine supplementation confers protection against SGPL1R222Q variant sphingosine phosphate lyase insufficiency syndrome. bioRxiv. 2026 May 14.. View in PubMed
  • Endothelial cell-selective adhesion molecule deficiency exhibits increased pulmonary vascular resistance due to impaired endothelial nitric oxide signaling. Am J Physiol Heart Circ Physiol. 2025 02 01; 328(2):H283-H293.. View in PubMed
  • PDE9A Inhibition Improves Coronary Microvascular Rarefaction and Left Ventricular Diastolic Dysfunction in the ZSF1 Rat Model of HFpEF. Microcirculation. 2024 11; 31(8):e12888.. View in PubMed
  • Phosphodiesterase 9A inhibition improves aging-related increase in pulmonary vascular resistance in mice. Geroscience. 2024 10; 46(5):5191-5202.. View in PubMed
  • Aldosterone Antagonism Is More Effective at Reducing Blood Pressure and Excessive Renal ENaC Activity in AngII-Infused Female Rats Than in Males. Hypertension. 2023 10; 80(10):2196-2208.. View in PubMed
  • The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s disease. Front Mol Neurosci. 2023; 16:1125932.. View in PubMed
  • Mice with endothelial cell-selective adhesion molecule deficiency develop coronary microvascular rarefaction and left ventricle diastolic dysfunction. Physiol Rep. 2023 03; 11(6):e15643.. View in PubMed
  • Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17. Geroscience. 2022 02; 44(1):349-369.. View in PubMed

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