Wendy Jean Mack, PhD

Professor of Population and Public Health Sciences, Gerontology and Biokinesiology and Physical Therapy

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Overview

Wendy Mack, PhD, is a professor of biostatistics in the Department of Preventive Medicine at the Keck School of Medicine of USC. She co-directs the department’s Division of Biostatistics graduate programs and directs Biostatistics Resources at the Southern California Clinical and Translational Science Institute (SC CTSI).

Professor Mack has more than 20 years of experience directing biostatistical and data coordination activities, primarily funded by the National Institutes of Health (NIH). Her expertise includes design, conduct and analysis of multiple single-centered and multi-centered clinical trials and observational studies. She also directs biostatistical activities for the USC Alzheimer’s Disease Research Center and for other basic and clinical research programs.

She has served on numerous NIH study sections for biostatistical expertise and has recently completed a term on the NHLBI Clinical Trials Review study section. Professor Mack received her doctorate from the University of Southern California. Her home is open to needy animals wandering by, and she dabbles in competitive dog obedience in her minimal spare time.

Research Funding

  • PHYSICAL FITNESS/CARDIOVASCULAR MORTALITY–FIREFIGHTERS
    NIH · R01HL058227 · Jul 1, 1999 – May 31, 2002 · Role: Principal Investigator
  • HORMONAL AND MEDICAL EXPOSURES AND FEMALE THYROID CANCER
    NIH · R03CA071409 · Sep 1, 1996 – Aug 31, 1998 · Role: Principal Investigator
  • CORRELATES OF ANGIOGRAPHIC CHANGES AND CORONARY EVENTS
    NIH · R03HL054532 · Apr 1, 1996 – Mar 31, 1998 · Role: Principal Investigator

Publications

  • Racial and Ethnic Disparities in Length of Stay for Pediatric Bacterial Tracheostomy-Associated Infections. Hosp Pediatr. 2026 Aug 01; 16(8):653-661.. View in PubMed
  • Cognitive performance modulates regional brain age differences in clinical anxiety and depression. J Affect Disord. 2026 Nov 15; 413:122237.. View in PubMed
  • A Pragmatic SMART Study of Medication and CBT Sequencing in Pediatric Anxiety Disorders: A Randomized Clinical Trial. Am J Psychiatry. 2026 Sep 01; 183(9):668-681.. View in PubMed
  • CNS target engagement of high-dose DHA supplementation in older adults at risk for dementia: a randomised, double-blind, placebo-controlled trial. EBioMedicine. 2026 Jul; 129:106316.. View in PubMed
  • Introducing the SAGE study: a multimodal protocol for testing a GABAergic mechanism of age-related episodic memory impairment across the sexes. BMJ Neurol Open. 2026; 8(1):e001546.. View in PubMed
  • Exceptionally low mortality despite widespread COVID-19 infection among Indigenous Tsimane and Moseten of Bolivia. Soc Sci Med. 2026 Sep; 404:119493.. View in PubMed
  • Sample sizes for randomized controlled trials utilizing Bayesian response adaptive randomization for continuous outcomes. J Biopharm Stat. 2026 Jun 11; 1.. View in PubMed
  • Tune In or Take the Stage? A Randomized Controlled Trial Comparing After-School Music and Theatre Training with Neuroimaging Outcomes for Youth. medRxiv. 2026 Jun 05.. View in PubMed
  • Perivascular space, brain functional connectivity and sleep: a healthy aging population study. NPJ Biol Timing Sleep. 2026 Jun 03; 3(1).. View in PubMed
  • Early Antibiotic Discontinuation for Children With a Positive Rapid Respiratory Viral Test Hospitalized for Suspected Bacterial Tracheostomy-Associated Infections. Pediatr Pulmonol. 2026 May; 61(5):e71652.. View in PubMed