Keck School Faculty

William Mack

William Mack

Professor of Neurological Surgery (Clinical Scholar)
Director, Neurointerventional Program, Keck Hospital of USC
Director, Neurosurgery Ambulatory Services, Keck Medical Center of USC
Vice Chair, Academic Affairs
GNH 3300 Health Sciences Campus Los Angeles

Bow Hunter's Syndrome: Surgical Management (Video) and Review of the LiteratureWorld Neurosurg. 2017 Jul; 103:953. e7-953. e12. . View in PubMed

Postpartum venous thromboembolism readmissions in the United StatesAm J Obstet Gynecol. 2018 10; 219(4):401. e1-401. e14. . View in PubMed

Fragmentation of postpartum readmissions in the United StatesAm J Obstet Gynecol. 2020 08; 223(2):252. e1-252. e14. . View in PubMed

Cyclic adenosine monophosphate-elevating agents inhibit amyloid-beta internalization and neurotoxicity: their action in Alzheimer's disease prevention Neural Regen Res. 2023 Dec; 18(12):2675-2676. . View in PubMed

Frailty is a Predictor of Increased Readmissions and Increased Postoperative Complications after Elective Treatment of Unruptured Aneurysms World Neurosurg. 2023 Nov 07. . View in PubMed

Persistent Inequities in Intravenous Thrombolysis for Acute Ischemic Stroke in the United States: Results from the Nationwide Inpatient Sample medRxiv. 2023 Oct 10. . View in PubMed

Subarachnoid Hemorrhage Trials: Cutting, Sliding, or Keeping mRS Scores and WFNS Grades medRxiv. 2023 Oct 02. . View in PubMed

Effect of Air Pollution Particulate Matter on Ischemic and Hemorrhagic Stroke: A Scoping Review Cureus. 2023 Oct; 15(10):e46694. . View in PubMed

The effect of COVID-19 on treatment and outcomes following ischemic stroke: A national assessment Clin Neurol Neurosurg. 2023 Oct; 233:107982. . View in PubMed

Usage of Mineralocorticoids and Isotonic Crystalloids in Subarachnoid Hemorrhage Patients in the United States medRxiv. 2023 Sep 29. . View in PubMed

Increased time to surgery and worse perioperative outcome in benign brain tumor patients with COVID-19 J Clin Neurosci. 2023 Sep 21; 117:20-26. . View in PubMed

Myelomeningocele repair at pediatric hospitals: association with routine discharge and shorter hospital stay J Neurosurg Pediatr. 2023 Sep 01; 32(3):376-383. . View in PubMed

GPT-4 Artificial Intelligence Model Outperforms ChatGPT, Medical Students, and Neurosurgery Residents on Neurosurgery Written Board-Like Questions World Neurosurg. 2023 Aug 18. . View in PubMed

Mortality following mechanical thrombectomy for ischemic stroke in patients with COVID-19 J Stroke Cerebrovasc Dis. 2023 Aug; 32(8):107171. . View in PubMed

Carotid artery stenting for asymptomatic stenosis is associated with decreased 30-day readmission at very high volume centers J Clin Neurosci. 2023 Aug; 114:1-8. . View in PubMed

Magnetic resonance imaging of white matter response to diesel exhaust particles Res Sq. 2023 Jul 18. . View in PubMed

Endoscopic endonasal approach for MRI-Negative Cushing's microadenoma Neurosurg Focus Video. 2023 Jul; 9(1):V5. . View in PubMed

Endovascular Embolization of Intracranial Meningiomas Neurosurg Clin N Am. 2023 Jul; 34(3):371-380. . View in PubMed

Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice J Neurosci Res. 2023 03; 101(3):384-402. . View in PubMed

Hospital Admissions from the Emergency Department and Subsequent Critical Care Interventions for Influenza during Pregnancy Am J Perinatol. 2023 02; 40(3):326-332. . View in PubMed

Roadmap for Development of a Strong, Diverse Research Workforce in Neurosurgery Neurosurgery. 2023 09 01; 93(3):e53-e58. . View in PubMed

Anatomic Considerations Guiding Single Versus Multiportal Endoscopic Approaches for Resection of Juvenile Nasopharyngeal Angiofibroma: Cases Series With Graded Multicorridor Resections Oper Neurosurg (Hagerstown). 2023 08 01; 25(2):150-160. . View in PubMed

Roadmap for Successful Research Training in Neurosurgery Neurosurgery. 2023 09 01; 93(3):e46-e52. . View in PubMed

Pediatric patients with malignant brain tumor treated at children's hospitals: association with fewer unplanned readmissions J Neurosurg Pediatr. 2023 09 01; 32(3):324-331. . View in PubMed

Coronavirus disease-19 is associated with decreased treatment access and worsened outcomes in malignant brain tumor patients Surg Neurol Int. 2023; 14:292. . View in PubMed

Combined open revascularization and endovascular treatment of complex intracranial aneurysms: case series Front Neurol. 2023; 14:1102496. . View in PubMed

Making a case for endovascular approaches for neural recording and stimulation J Neural Eng. 2023 01 25; 20(1). . View in PubMed

Interhospital transfer of pediatric patients with malignant brain tumor not associated with increased mortality, but safe routine discharge J Neurosurg Pediatr. 2023 02 01; 31(2):124-131. . View in PubMed

ChatGPT versus the neurosurgical written boards: a comparative analysis of artificial intelligence/machine learning performance on neurosurgical board-style questions J Neurosurg. 2023 03 24; 139(3):904-911. . View in PubMed

Flavonoid quercetin and its glucuronide and sulfate conjugates bind to 67-kDa laminin receptor and prevent neuronal cell death induced by serum starvation Biochem Biophys Res Commun. 2023 09 03; 671:116-123. . View in PubMed

Tobacco Use Is Associated With Increased 90-Day Readmission Among Patients Undergoing Surgery for Degenerative Spine Disease Global Spine J. 2022 Jun; 12(5):787-794. . View in PubMed

Minocycline decreases blood-brain barrier permeability following aneurysmal subarachnoid hemorrhage: a randomized, double-blind, controlled trial J Neurosurg. 2022 May 01; 136(5):1251-1259. . View in PubMed

cAMP-induced decrease in cell-surface laminin receptor and cellular prion protein attenuates amyloid-ß uptake and amyloid-ß-induced neuronal cell death FEBS Lett. 2022 11; 596(22):2914-2927. . View in PubMed

Interhospital transfer of patients with malignant brain tumors undergoing resection is associated with routine discharge Clin Neurol Neurosurg. 2022 10; 221:107372. . View in PubMed

Getting ahead of stroke J Neurointerv Surg. 2022 08; 14(8):743-744. . View in PubMed

2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association Stroke. 2022 07; 53(7):e282-e361. . View in PubMed

Disparities in the Surgical Treatment of Adult Spine Diseases: A Systematic ReviewWorld Neurosurg. 2022 02; 158:290-304. e1. . View in PubMed

Disparities in the Surgical Treatment of Cerebrovascular Pathologies: A Contemporary Systematic ReviewWorld Neurosurg. 2022 02; 158:244-257. e1. . View in PubMed

Stimulating neurosurgery department research via goal-directed research training of residents J Neurosurg. 2022 12 09; 138(5):1478-1481. . View in PubMed

Neurotoxicity of Diesel Exhaust Particles J Alzheimers Dis. 2022; 89(4):1263-1278. . View in PubMed

Nogo-A receptor internalization by cyclic adenosine monophosphate in overcoming axonal growth inhibitors after stroke Neural Regen Res. 2022 Jan; 17(1):91-92. . View in PubMed

Readmissions after ventricular shunting in pediatric patients with hydrocephalus: a Nationwide Readmissions Database analysis J Neurosurg Pediatr. 2021 Aug 20; 28(5):553-562. . View in PubMed

Comorbid depression in surgical cancer patients associated with non-routine discharge and readmission Surg Oncol. 2021 Jun; 37:101533. . View in PubMed

Investigating the blood-spinal cord barrier in preclinical models: a systematic review of in vivo imaging techniques Spinal Cord. 2021 Jun; 59(6):596-612. . View in PubMed

Risk for postpartum readmissions and associated complications based on maternal age J Matern Fetal Neonatal Med. 2021 May; 34(9):1375-1381. . View in PubMed

Neuroprotective effect of minocycline against acute brain injury in clinical practice: A systematic review J Clin Neurosci. 2021 Apr; 86:50-57. . View in PubMed

Increasing Prevalence of Frailty and Its Association with Readmission and Mortality Among Hospitalized Patients with IBD Dig Dis Sci. 2021 12; 66(12):4178-4190. . View in PubMed

Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID-19 pandemic Stroke Vasc Neurol. 2021 12; 6(4):542-552. . View in PubMed

Evaluating Medicaid expansion benefits for patients with cancer: National Cancer Database analysis and systematic review J Cancer Policy. 2021 09; 29:100292. . View in PubMed

Air Pollution Particulate Matter Exposure and Chronic Cerebral Hypoperfusion and Measures of White Matter Injury in a Murine Model Environ Health Perspect. 2021 08; 129(8):87006. . View in PubMed

A systematic review of next-generation point-of-care stroke diagnostic technologies Neurosurg Focus. 2021 07; 51(1):E11. . View in PubMed

Transcranial eddy current damping sensors for detection and imaging of hemorrhagic stroke: feasibility in benchtop experimentation Neurosurg Focus. 2021 07; 51(1):E15. . View in PubMed

Global impact of COVID-19 on stroke care Int J Stroke. 2021 07; 16(5):573-584. . View in PubMed

Complications associated with lumbar drain placement for endovascular aortic repairJ Vasc Surg. 2021 05; 73(5):1513-1524. e2. . View in PubMed

Tracking Scan to Incision Time in Patients with Emergent Operative Traumatic Brain Injuries as a Measure for Systems-Based Practice in Neurosurgical Trainees World Neurosurg. 2021 05; 149:e491-e497. . View in PubMed

Frailty Is Associated with In-Hospital Morbidity and Nonroutine Disposition in Brain Tumor Patients Undergoing Craniotomy World Neurosurg. 2021 02; 146:e1045-e1053. . View in PubMed

Risk Factors for Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage: A Population-Based Study of 8346 Patients World Neurosurg. 2021 01; 145:e233-e241. . View in PubMed

Tobacco Use Is Associated with Readmission within 90 Days after Craniotomy Clin Neurol Neurosurg. 2021 01; 200:106383. . View in PubMed

Postpartum Psychiatric Admissions in the United States Am J Perinatol. 2021 01; 38(2):115-121. . View in PubMed

Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion Front Immunol. 2021; 12:785519. . View in PubMed

Letter to the EditorScoring change for Step 1 of the United States Medical Licensing Examination. J Neurosurg. 2021 01 22; 134(6):2012-2013. . View in PubMed

Urban Air Pollution Nanoparticles from Los Angeles: Recently Decreased Neurotoxicity J Alzheimers Dis. 2021; 82(1):307-316. . View in PubMed

Middle Cerebral Artery Thrombectomy: Clinical Findings and Technical Pearls: 2-Dimensional Operative Video Oper Neurosurg (Hagerstown). 2021 07 15; 21(2):E107-E108. . View in PubMed

Postpartum hemorrhage and risk for postpartum readmission J Matern Fetal Neonatal Med. 2021 Jan; 34(2):187-194. . View in PubMed

Nanoparticulate matter exposure results in white matter damage and an inflammatory microglial response in an experimental murine model PLoS One. 2021; 16(7):e0253766. . View in PubMed

Influence of thrombectomy volume on non-physician staff burnout and attrition in neurointerventional teams J Neurointerv Surg. 2020 Dec; 12(12):1199-1204. . View in PubMed

Unusual Pattern of Arterial Macrothrombosis Causing Stroke in a Young Adult Recovered from COVID-19 J Stroke Cerebrovasc Dis. 2020 Dec; 29(12):105353. . View in PubMed

Readmission with venous thromboembolism after surgical treatment by primary cancer site Surg Oncol. 2020 Dec; 35:268-275. . View in PubMed

National Institutes of Health grant opportunities for the neurointerventionalist: preparation and choosing the right mechanism J Neurointerv Surg. 2020 Nov 25. . View in PubMed

Strategies for writing a successful National Institutes of Health grant proposal for the early-career neurointerventionalist J Neurointerv Surg. 2020 Nov 25. . View in PubMed

COVID-19 and neurointerventional service worldwide: a survey of the European Society of Minimally Invasive Neurological Therapy (ESMINT), the Society of NeuroInterventional Surgery (SNIS), the Sociedad Iberolatinoamericana de Neuroradiologia Diagnostica y Terapeutica (SILAN), the Society of Vascular and Interventional Neurology (SVIN), and the World Federation of Interventional and Therapeutic Neuroradiology (WFITN) J Neurointerv Surg. 2020 Aug; 12(8):726-730. . View in PubMed

Comparison of Rates and Outcomes of Readmission to Index vs Non-index Hospitals After Intravenous Thrombolysis in Acute Stroke Patients Cureus. 2020 Jul 01; 12(7):e8952. . View in PubMed

Increased 30-day readmission rate after craniotomy for tumor resection at safety net hospitals in small metropolitan areas J Neurooncol. 2020 May; 148(1):141-154. . View in PubMed

Postpartum length of stay and risk for readmission among women with preeclampsia J Matern Fetal Neonatal Med. 2020 Apr; 33(7):1086-1094. . View in PubMed

Frequency, predictors, and outcomes of readmission to index versus non-index hospitals after mechanical thrombectomy in patients with ischemic stroke J Neurointerv Surg. 2020 Feb; 12(2):136-141. . View in PubMed

Comorbid depression associated with non-routine discharge following craniotomy for low-grade gliomas and benign tumors - a nationwide readmission database analysis Acta Neurochir (Wien). 2020 11; 162(11):2671-2681. . View in PubMed

Predictors of readmission after craniotomy for meningioma resection: a nationwide readmission database analysis Acta Neurochir (Wien). 2020 11; 162(11):2637-2646. . View in PubMed

Research and neurointerventional surgery: a roadmap of federal funding opportunities J Neurointerv Surg. 2020 11; 12(11):1035-1036. . View in PubMed

Effect of Comorbid Depression on Surgical Outcomes After Craniotomy for Malignant Brain Tumors: A Nationwide Readmission Database Analysis World Neurosurg. 2020 10; 142:e458-e473. . View in PubMed

Discrepancy in Neurologic Outcomes Following Aneurysmal Subarachnoid Hemorrhage as a Function of Socioeconomic Class World Neurosurg. 2020 06; 138:e787-e794. . View in PubMed

Society of NeuroInterventional Surgery recommendations for the care of emergent neurointerventional patients in the setting of COVID-19 J Neurointerv Surg. 2020 06; 12(6):539-541. . View in PubMed

Acute Venous Thromboembolism Risk Highest Within 60 Days After Discharge From the Hospital in Patients With Inflammatory Bowel DiseasesClin Gastroenterol Hepatol. 2020 05; 18(5):1133-1141. e3. . View in PubMed

Risk of Stillbirth after Antepartum Hospitalization for Hypertensive Diseases of Pregnancy Am J Perinatol. 2020 01; 37(1):66-72. . View in PubMed

Cyclic-AMP induces Nogo-A receptor NgR1 internalization and inhibits Nogo-A-mediated collapse of growth cone Biochem Biophys Res Commun. 2020 03 12; 523(3):678-684. . View in PubMed

Effects of ambient particulate matter on vascular tissue: a review J Toxicol Environ Health B Crit Rev. 2020 10 02; 23(7):319-350. . View in PubMed

Failure of Flow Diverter Therapy: Predictors and Management Strategies Neurosurgery. 2020 01 01; 86(Suppl 1):S64-S73. . View in PubMed

Outcomes After Minimally Invasive Parafascicular Surgery for Intracerebral Hemorrhage: A Single-Center Experience World Neurosurg. 2019 Dec; 132:e520-e528. . View in PubMed

Older Age Is Not Associated with Worse Outcomes Following Decompressive Hemicraniectomy for Spontaneous Intracerebral Hemorrhage J Stroke Cerebrovasc Dis. 2019 Nov; 28(11):104320. . View in PubMed

Increased complication and mortality among non-index hospital readmissions after brain tumor resection is associated with low-volume readmitting hospitals J Neurosurg. 2019 Oct 04; 1-13. . View in PubMed

Nonindex Readmission After Ruptured Brain Aneurysm Treatment Is Associated with Higher Morbidity and Repeat Readmission World Neurosurg. 2019 Oct; 130:e753-e759. . View in PubMed

Cell signaling associated with internalization of 67 kDa laminin receptor (67LR) by soluble laminin and its implication for protection against neurodegenerative diseases Neural Regen Res. 2019 Sep; 14(9):1513-1514. . View in PubMed

Vascular Oper Neurosurg (Hagerstown). 2019 Aug 01; 17(Suppl 2):S76-S118. . View in PubMed

Neuroendovascular surgery: a modern family J Neurointerv Surg. 2019 Aug; 11(8):733-734. . View in PubMed

Early Readmission After Ventricular Shunting in Adults with Hydrocephalus: A Nationwide Readmission Database Analysis World Neurosurg. 2019 Aug; 128:e38-e50. . View in PubMed

A joint statement from the Neurointerventional Societies: our position on operator experience and training for stroke thrombectomy J Neurointerv Surg. 2019 Jun; 11(6):533-534. . View in PubMed

Predictors of Venous Thromboembolism After Nonemergent Craniotomy: A Nationwide Readmission Database Analysis World Neurosurg. 2019 Feb; 122:e1102-e1110. . View in PubMed

Medical Student Neurosurgery Training Camp: Updates Following 2019 Course Expansion World Neurosurg. 2019 10; 130:561-563. . View in PubMed

Venous Thromboembolism After Degenerative Spine Surgery: A Nationwide Readmissions Database Analysis World Neurosurg. 2019 05; 125:e165-e174. . View in PubMed

Hypertensive Postpartum Admissions Among Women Without a History of Hypertension or Preeclampsia Obstet Gynecol. 2019 04; 133(4):712-719. . View in PubMed

Postpartum readmissions among women with opioid use disorder Am J Obstet Gynecol MFM. 2019 03; 1(1):89-98. . View in PubMed

Experimental chronic cerebral hypoperfusion results in decreased pericyte coverage and increased blood-brain barrier permeability in the corpus callosum J Cereb Blood Flow Metab. 2019 02; 39(2):240-250. . View in PubMed

State of the Union in Open Neurovascular Training World Neurosurg. 2019 02; 122:e553-e560. . View in PubMed

Readmission following inpatient stereotactic radiosurgery for brain tumors J Radiosurg SBRT. 2019; 6(2):101-119. . View in PubMed

Acute Left M1 Stroke With Critical Left Internal Carotid Artery Stenosis: Video Case Neurosurgery. 2019 07 01; 85(suppl_1):S73. . View in PubMed

A3-A3 Anastomosis in the Management of Complex Anterior Cerebral Artery Aneurysms: Experience With in Situ Bypass and Lessons Learned From Pseudoaneurysm Cases Oper Neurosurg (Hagerstown). 2019 09 01; 17(3):247-260. . View in PubMed

Increased Hospital Surgical Volume Reduces Rate of 30- and 90-Day Readmission After Acoustic Neuroma Surgery Neurosurgery. 2019 03 01; 84(3):726-732. . View in PubMed

TARGET® Intracranial Aneurysm Coiling Prospective Multicenter Registry: Final Analysis of Peri-Procedural and Long-Term Safety and Efficacy Results Front Neurol. 2019; 10:737. . View in PubMed

The Continued Role and Value of Imaging for Acute Ischemic Stroke Neurosurgery. 2019 07 01; 85(suppl_1):S23-S30. . View in PubMed

Treatment at Safety-Net Hospitals Is Associated with Delays in Coil Embolization in Patients with Subarachnoid Hemorrhage World Neurosurg. 2018 Dec; 120:e434-e439. . View in PubMed

Predictors of Surgical Site Infection After Nonemergent Craniotomy: A Nationwide Readmission Database Analysis World Neurosurg. 2018 Dec; 120:e440-e452. . View in PubMed

Safety-Net Hospitals Have Higher Complication and Mortality Rates in the Neurosurgical Management of Traumatic Brain Injuries World Neurosurg. 2018 Nov; 119:e284-e293. . View in PubMed

Estradiol Protects White Matter of Male C57BL6J Mice against Experimental Chronic Cerebral Hypoperfusion J Stroke Cerebrovasc Dis. 2018 Jul; 27(7):1743-1751. . View in PubMed

Value of pituitary gland MRI at 7 T in Cushing's disease and relationship to inferior petrosal sinus sampling: case report J Neurosurg. 2018 Mar 01; 1-5. . View in PubMed

Neuroendovascular management of emergent large vessel occlusion: update on the technical aspects and standards of practice by the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery J Neurointerv Surg. 2018 Mar; 10(3):315-320. . View in PubMed

Thrombectomy stroke centers: The current threat to regionalizing stroke care J Neurointerv Surg. 2018 Feb; 10(2):99-101. . View in PubMed

Commentary on 'Is periprocedural sedation during acute stroke therapy associated with poorer functional outcomes? ' J Neurointerv Surg. 2018 07; 10(Suppl 1):i39.. View in PubMed

In the thrombectomy era, triage in the field improves care J Neurointerv Surg. 2018 07; 10(7):607-608. . View in PubMed

Uncovering the Rosetta Stone: Report from the First Annual Conference on Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical Transl Stroke Res. 2018 06; 9(3):258-266. . View in PubMed

Permeability imaging as a predictor of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage J Cereb Blood Flow Metab. 2018 06; 38(6):973-979. . View in PubMed

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system Nat Med. 2018 03; 24(3):326-337. . View in PubMed

Hospital and demographic characteristics associated with inpatient neurological services in the United States Clin Neurol Neurosurg. 2018 01; 164:39-43. . View in PubMed

Timing and Risk Factors of Postpartum Stroke Obstet Gynecol. 2018 01; 131(1):70-78. . View in PubMed

Efficacy and Outcomes of Posterior Inferior Cerebellar Artery (PICA) Bypass for Proximal PICA and Vertebral Artery-PICA Aneurysms: A Case Series Oper Neurosurg (Hagerstown). 2018 10 01; 15(4):395-403. . View in PubMed

Predictors of 30- and 90-day readmission following craniotomy for malignant brain tumors: analysis of nationwide data J Neurooncol. 2018 Jan; 136(1):87-94. . View in PubMed

Descending Branch of the Lateral Circumflex Femoral Artery Graft for Posterior Inferior Cerebellar Artery Revascularization Oper Neurosurg (Hagerstown). 2018 09 01; 15(3):285-291. . View in PubMed

Commentary: Trends in the Use of Deep Brain Stimulation for Parkinson Disease Neurosurgery. 2018 12 01; 83(6):E244-E256. . View in PubMed

Fusiform vertebral artery aneurysms involving the posterior inferior cerebellar artery origin associated with the sole angiographic anterior spinal artery origin: technical case report and treatment paradigm proposal J Neurosurg. 2018 10 01; 1-7. . View in PubMed

Laminin-1 induces endocytosis of 67KDa laminin receptor and protects Neuroscreen-1 cells against death induced by serum withdrawal Biochem Biophys Res Commun. 2018 01 01; 495(1):230-237. . View in PubMed

Orthogonal Catheter Access for Stent Assisted Coiling of Posterior Cerebral Artery Aneurysm Oper Neurosurg (Hagerstown). 2018 01 01; 14(1):85. . View in PubMed

Nanoparticulate matter exposure results in neuroinflammatory changes in the corpus callosum PLoS One. 2018; 13(11):e0206934. . View in PubMed

Development of a Perfusion-Based Cadaveric Simulation Model Integrated into Neurosurgical Training: Feasibility Based On Reconstitution of Vascular and Cerebrospinal Fluid Systems Oper Neurosurg (Hagerstown). 2018 01 01; 14(1):72-80. . View in PubMed

Factors associated with burnout among US neurosurgery residents: a nationwide survey J Neurosurg. 2018 11 01; 129(5):1349-1363. . View in PubMed

A survey of intracranial aneurysm treatment practices among United States physicians J Neurointerv Surg. 2018 Jan; 10(1):44-49. . View in PubMed

Neuroprotective strategies following intraparenchymal hemorrhage J Neurointerv Surg. 2017 Dec; 9(12):1202-1207. . View in PubMed

Chronic cerebral hypoperfusion induced by bilateral carotid artery stenosis causes selective recognition impairment in adult mice Neurol Res. 2017 Oct; 39(10):910-917. . View in PubMed

The Weekend Effect on Morbidity and Mortality Among Pediatric Epilepsy AdmissionsPediatr Neurol. 2017 Sep; 74:24-31. e1. . View in PubMed

Clinical effects of air pollution on the central nervous system; a review J Clin Neurosci. 2017 Sep; 43:16-24. . View in PubMed

The effect of NACHRI children's hospital designation on outcome in pediatric malignant brain tumors J Neurosurg Pediatr. 2017 Aug; 20(2):149-157. . View in PubMed

Selective embolization of ruptured feeding artery aneurysm followed by resection of arteriovenous malformation Neurosurg Focus. 2017 Jul; 43(VideoSuppl1):V4. . View in PubMed

ACR Appropriateness Criteria® Cerebrovascular Disease J Am Coll Radiol. 2017 May; 14(5S):S34-S61. . View in PubMed

Impact of the 2003 ACGME Resident Duty Hour Reform on Hospital-Acquired Conditions: A National Retrospective Analysis J Grad Med Educ. 2017 Apr; 9(2):215-221. . View in PubMed

Neuroprotective delivery platforms as an adjunct to mechanical thrombectomy Neurosurg Focus. 2017 Apr; 42(4):E4. . View in PubMed

Minimally Invasive Surgical Approaches for Chronic Subdural Hematomas Neurosurg Clin N Am. 2017 Apr; 28(2):219-227. . View in PubMed

Trends in Ventriculostomy-Associated Infections and Mortality in Aneurysmal Subarachnoid Hemorrhage: Data From the Nationwide Inpatient Sample World Neurosurg. 2017 Mar; 99:599-604. . View in PubMed

Stent retrievers and acute stroke treatment: a rapid learning curve for experienced neurointerventional surgeons J Neurointerv Surg. 2017 Feb; 9(2):113-114. . View in PubMed

Post-thrombectomy management of the ELVO patient: Guidelines from the Society of NeuroInterventional Surgery J Neurointerv Surg. 2017 12; 9(12):1258-1266. . View in PubMed

Preventable complications in epilepsy admissions: The "July effect" Epilepsy Res. 2017 11; 137:101-106. . View in PubMed

Prehospital care delivery and triage of stroke with emergent large vessel occlusion (ELVO): report of the Standards and Guidelines Committee of the Society of Neurointerventional Surgery J Neurointerv Surg. 2017 08; 9(8):802-812. . View in PubMed

Potentially preventable complications in epilepsy admissions: The "weekend effect" Epilepsy Behav. 2017 05; 70(Pt A):50-56. . View in PubMed

Introduction: New techniques and technologies in the management of ischemic stroke Neurosurg Focus. 2017 04; 42(4):E1. . View in PubMed

Pitfalls of administrative database analysis are evident when assessing the 'weekend effect' in stroke Evid Based Med. 2017 03; 22(1):35. . View in PubMed

Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients Neuroimage Clin. 2017; 15:239-246. . View in PubMed

Risk factors associated with the surgical management of craniopharyngiomas in pediatric patients: analysis of 1961 patients from a national registry database Neurosurg Focus. 2016 Dec; 41(6):E8. . View in PubMed

The impact of evidence: evolving therapy for acute ischemic stroke in a large healthcare system J Neurointerv Surg. 2016 Nov; 8(11):1129-1135. . View in PubMed

Supplementing mechanical thrombectomy with neuroprotection J Neurointerv Surg. 2016 Nov; 8(11):1095-1096. . View in PubMed

Trends in Transient Ischemic Attack Hospitalizations in the United States J Am Heart Assoc. 2016 Sep 24; 5(9). . View in PubMed

Infection rate correlated with time to repair of open neural tube defects (myelomeningoceles): an institutional and national study Childs Nerv Syst. 2016 Sep; 32(9):1675-81. . View in PubMed

Novel Treatments in Neuroprotection for Aneurysmal Subarachnoid Hemorrhage Curr Treat Options Neurol. 2016 Aug; 18(8):38. . View in PubMed

Cross-Sectional Analysis on Racial and Economic Disparities Affecting Mortality in Preterm Infants with Posthemorrhagic Hydrocephalus World Neurosurg. 2016 Apr; 88:399-410. . View in PubMed

Counteraction of Nogo-A and axonal growth inhibitors by green tea polyphenols and other natural products Neural Regen Res. 2016 Apr; 11(4):545-6. . View in PubMed

Strategic and Technical Considerations for the Endovascular Embolization of Intracranial Meningiomas Neurosurg Clin N Am. 2016 Apr; 27(2):155-66. . View in PubMed

Evaluation of time to aneurysm treatment following subarachnoid hemorrhage: comparison of patients treated with clipping versus coiling J Neurointerv Surg. 2016 Apr; 8(4):373-7. . View in PubMed

Trends in hospitalization of preterm infants with intraventricular hemorrhage and hydrocephalus in the United States, 2000-2010 J Neurosurg Pediatr. 2016 Mar; 17(3):260-9. . View in PubMed

Reevaluating the weekend effect on patients with hydrocephalus undergoing operative shunt intervention J Neurosurg Pediatr. 2016 Feb; 17(2):156-162. . View in PubMed

Prophylaxis of Venous Thrombosis in Neurocritical Care Patients: An Evidence-Based Guideline: A Statement for Healthcare Professionals from the Neurocritical Care Society Neurocrit Care. 2016 Feb; 24(1):47-60. . View in PubMed

Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model PLoS One. 2016; 11(4):e0153376. . View in PubMed

Assessing characteristics of RNA amplification methods for single cell RNA sequencing BMC Genomics. 2016 11 24; 17(1):966. . View in PubMed

Trends in Acute Ischemic Stroke Hospitalizations in the United States J Am Heart Assoc. 2016 05 11; 5(5). . View in PubMed

The Structural and Genetic Variations in Intracerebral Vasculature World Neurosurg. 2015 Nov; 84(5):1196-7. . View in PubMed

The importance of preoperative diagnosis of blister aneurysms J Clin Neurosci. 2015 Sep; 22(9):1408-12. . View in PubMed

Variability in Criteria for Emergency Medical Services Routing of Acute Stroke Patients to Designated Stroke Center Hospitals West J Emerg Med. 2015 Sep; 16(5):743-6. . View in PubMed

Too much guidance J Neurointerv Surg. 2015 Sep; 7(9):626-7. . View in PubMed

Casting a wide net: the unique diversity of neuroendovascular surgery J Neurointerv Surg. 2015 Aug; 7(8):549-50. . View in PubMed

Evaluation of weekend admission on the prevalence of hospital acquired conditions in patients receiving thoracolumbar fusions J Clin Neurosci. 2015 Aug; 22(8):1349-54. . View in PubMed

Evaluation of Effect of Weekend Admission on the Prevalence of Hospital-Acquired Conditions in Patients Receiving Cervical Fusions World Neurosurg. 2015 Jul; 84(1):58-68. . View in PubMed

The july effect: an analysis of never events in the nationwide inpatient sample J Hosp Med. 2015 Jul; 10(7):432-8. . View in PubMed

Racial and socioeconomic disparities in outcomes following pediatric cerebrospinal fluid shunt procedures J Neurosurg Pediatr. 2015 Jun; 15(6):560-6. . View in PubMed

Going Big to Explore the Detail World Neurosurg. 2015 Jun; 83(6):1041-3. . View in PubMed

Thrombectomy for acute ischemic stroke: an evidence-based treatment J Neurointerv Surg. 2015 May; 7(5):314-5. . View in PubMed

Incidence of "never events" among weekend admissions versus weekday admissions to US hospitals: national analysis BMJ. 2015 Apr 15; 350:h1460. . View in PubMed

Novel application of pre-operative vertebral body embolization to reduce intraoperative blood loss during a three-column spinal osteotomy for non-oncologic spinal deformity J Clin Neurosci. 2015 Apr; 22(4):765-7. . View in PubMed

A research roadmap of future endovascular stroke trials J Neurointerv Surg. 2015 Feb; 7(2):82-3. . View in PubMed

Demographic factors, outcomes, and patient access to transsphenoidal surgery for Cushing's disease: analysis of the Nationwide Inpatient Sample from 2002 to 2010 Neurosurg Focus. 2015 Feb; 38(2):E2. . View in PubMed

Endovascular therapy for acute ischemic stroke is indicated and evidence based: a position statement J Neurointerv Surg. 2015 Feb; 7(2):79-81. . View in PubMed

Balloon test occlusion in the setting of vessel sacrifice: procedural refinements and adjunct assessment measures World Neurosurg. 2015 Jan; 83(1):7-8. . View in PubMed

Final results of the multicenter, prospective Axium MicroFX for Endovascular Repair of IntraCranial Aneurysm Study (AMERICA) J Neurointerv Surg. 2015 Jan; 7(1):40-3. . View in PubMed

Hospital and demographic characteristics associated with advanced primary stroke center designation Stroke. 2014 Dec; 45(12):3717-9. . View in PubMed

Health disparities in time to aneurysm clipping/coiling among aneurysmal subarachnoid hemorrhage patients: a national study World Neurosurg. 2014 Dec; 82(6):1071-6. . View in PubMed

Matrix metalloproteinase-9: dual role and temporal profile in intracerebral hemorrhage J Stroke Cerebrovasc Dis. 2014 Nov-Dec; 23(10):2498-2505. . View in PubMed

On keeping of our heritage: family trees, mentorship and the West Coast offense J Neurointerv Surg. 2014 Oct; 6(8):565-6. . View in PubMed

Platelet function inhibitors and platelet function testing in neurointerventional procedures J Neurointerv Surg. 2014 Oct; 6(8):567-77. . View in PubMed

The impact of patient age and comorbidities on the occurrence of "never events" in cerebrovascular surgery: an analysis of the Nationwide Inpatient Sample J Neurosurg. 2014 Sep; 121(3):580-6. . View in PubMed

Early results of the Axium MicroFX for Endovascular Repair of IntraCranial Aneurysm (AMERICA) study: a multicenter prospective observational registry J Neurointerv Surg. 2014 Sep; 6(7):495-9. . View in PubMed

A persistent primitive hypoglossal artery arising from the external carotid artery associated with subarachnoid hemorrhageWorld Neurosurg. 2014 Jul-Aug; 82(1-2):239. e1-3. . View in PubMed

Balloon-assisted transarterial embolization of type 1 spinal dural arteriovenous fistula Neurosurg Focus. 2014 Jul; 37(1 Suppl):1. . View in PubMed

Plaque morphology and embolic protection strategies in carotid artery stenting World Neurosurg. 2014 Jul-Aug; 82(1-2):e179-81. . View in PubMed

Racial and socioeconomic disparities in incidence of hospital-acquired complications following cerebrovascular procedures Neurosurgery. 2014 Jul; 75(1):43-50. . View in PubMed

Transarterial embolization of an anterior fossa cranial base dural arteriovenous fistula Neurosurg Focus. 2014 Jul; 37(1 Suppl):1. . View in PubMed

Expansion of US. emergency medical service routing for stroke care: 2000-2010. West J Emerg Med. 2014 Jul; 15(4):499-503. . View in PubMed

Anticoagulation in the setting of intracerebral hemorrhage: controversies in resuming therapy World Neurosurg. 2014 May-Jun; 81(5-6):669-70. . View in PubMed

Effects of ionizing radiation on cerebral vasculature World Neurosurg. 2014 Mar-Apr; 81(3-4):490-1. . View in PubMed

Racial and socioeconomic disparities in access to mechanical revascularization procedures for acute ischemic stroke J Stroke Cerebrovasc Dis. 2014 Feb; 23(2):327-34. . View in PubMed

The artery of percheron and etiologies of bilateral thalamic stroke World Neurosurg. 2014 Jan; 81(1):80-2. . View in PubMed

Health-related quality of life after aneurysmal subarachnoid hemorrhage: interplay between physical, cognitive, and emotional factors World Neurosurg. 2014 Jan; 81(1):37-9. . View in PubMed

Considering radiation exposure during diagnostic and therapeutic procedures for arteriovenous malformations in the setting of pregnancy World Neurosurg. 2014 Jan; 81(1):22-4. . View in PubMed

Magnesium: potential roles in neurovascular disease Front Neurol. 2014; 5:52. . View in PubMed

Vertebral augmentation: report of the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery J Neurointerv Surg. 2014 Jan; 6(1):7-15. . View in PubMed

Genomic and transcriptome analysis revealing an oncogenic functional module in meningiomas Neurosurg Focus. 2013 Dec; 35(6):E3. . View in PubMed

A review of epigenetic and gene expression alterations associated with intracranial meningiomas Neurosurg Focus. 2013 Dec; 35(6):E5. . View in PubMed

A proposed grading system for standardizing tumor consistency of intracranial meningiomas Neurosurg Focus. 2013 Dec; 35(6):E1. . View in PubMed

Impact of emergency medical services stroke routing protocols on Primary Stroke Center certification in California Stroke. 2013 Dec; 44(12):3584-6. . View in PubMed

Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):1263-9. . View in PubMed

Trends in cancer diagnoses among inpatients hospitalized with stroke J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):1146-50. . View in PubMed

Emerging experimental therapies for intracerebral hemorrhage: targeting mechanisms of secondary brain injury Neurosurg Focus. 2013 May; 34(5):E9. . View in PubMed

Characterizing immunoglobulin repertoire from whole blood by a personal genome sequencer PLoS One. 2013; 8(9):e75294. . View in PubMed

Invasive and noninvasive multimodal bedside monitoring in subarachnoid hemorrhage: a review of techniques and available data Neurol Res Int. 2013; 2013:987934. . View in PubMed

Medical Management of Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage: A Review of Current and Emerging Therapeutic Interventions Neurol Res Int. 2013; 2013:462491. . View in PubMed

Matrix Metalloproteinases in Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage Neurol Res Int. 2013; 2013:943761. . View in PubMed

White matter injury due to experimental chronic cerebral hypoperfusion is associated with C5 deposition PLoS One. 2013; 8(12):e84802. . View in PubMed

The role of epigenetic modification in tumorigenesis and progression of pituitary adenomas: a systematic review of the literature PLoS One. 2013; 8(12):e82619. . View in PubMed

Advanced imaging modalities in the detection of cerebral vasospasm Neurol Res Int. 2013; 2013:415960. . View in PubMed

Cerebral vasospasm in traumatic brain injury Neurol Res Int. 2013; 2013:415813. . View in PubMed

DNA methylation in the malignant transformation of meningiomas PLoS One. 2013; 8(1):e54114. . View in PubMed

Simulation of a high-flow extracranial-intracranial bypass using a radial artery graft in a novel fresh tissue model Neurosurgery. 2012 Dec; 71(2 Suppl Operative):ons315-19; discussion ons 319-20. . View in PubMed

The Orbit Galaxy XTRASOFT Coils: A Multicenter Study of Coil Safety and Efficacy in Both Ruptured and Unruptured Cerebral Aneurysms J Vasc Interv Neurol. 2012 Jun; 5(1):17-21. . View in PubMed

Recurrence of "cured" dural arteriovenous fistulas after Onyx embolization Neurosurg Focus. 2012 May; 32(5):E12. . View in PubMed

Mechanical thrombectomy for acute ischemic stroke using the MERCI retriever and penumbra aspiration systems World Neurosurg. 2011 Dec; 76(6 Suppl):S16-23. . View in PubMed

Preclinical evaluation of postischemic dehydroascorbic Acid administration in a large-animal stroke model Transl Stroke Res. 2011 Sep; 2(3):399-403. . View in PubMed

Paradoxical exacerbation of neuronal injury in reperfused stroke despite improved blood flow and reduced inflammation in early growth response-1 gene-deleted mice Neurol Res. 2011 Sep; 33(7):717-25. . View in PubMed

Re: Evidence-based treatment of carotid stenosis: is the evidence strong enough? Neurosurg Focus. 2011 Jun; 30(6):E3.. View in PubMed

Therapeutic hypothermia in acute ischemic stroke Neurosurg Focus. 2011 Jun; 30(6):E17. . View in PubMed

Molecular genetics of meningiomas: a systematic review of the current literature and potential basis for future treatment paradigms Neurosurg Focus. 2011 May; 30(5):E7. . View in PubMed

Endovascular management of anterior cranial fossa dural arteriovenous malformationsA technical report and anatomical discussion. Interv Neuroradiol. 2011 Mar; 17(1):93-103. . View in PubMed

The complement cascade: new avenues in stroke therapy Curr Vasc Pharmacol. 2009 Jul; 7(3):287-92. . View in PubMed

Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial J Neurosurg. 2009 May; 110(5):961-7. . View in PubMed

Radiolucent hair accessories causing depressed skull fracture following blunt cranial trauma J Neurosurg Pediatr. 2008 Dec; 2(6):424-6. . View in PubMed

Doppler ultrasonography screening of poor-grade subarachnoid hemorrhage patients increases the diagnosis of deep venous thrombosis Neurol Res. 2008 Nov; 30(9):889-92. . View in PubMed

Plasma levels of vascular endothelial growth factor after treatment for cerebral arteriovenous malformations Stroke. 2008 Aug; 39(8):2274-9. . View in PubMed

Protective effect of C5a receptor inhibition after murine reperfused stroke Neurosurgery. 2008 Jul; 63(1):122-5; discussion 125-6. . View in PubMed

Deep hypothermic circulatory arrest for complex cerebral aneurysms: lessons learned Neurosurgery. 2008 Jun; 62(6 Suppl 3):1311-23. . View in PubMed

C3a receptor modulation of granulocyte infiltration after murine focal cerebral ischemia is reperfusion dependent J Cereb Blood Flow Metab. 2008 May; 28(5):1048-58. . View in PubMed

Pupillary reactivity upon hospital admission predicts long-term outcome in poor grade aneurysmal subarachnoid hemorrhage patients Neurocrit Care. 2008; 8(3):374-9. . View in PubMed

The role of complement in stroke therapy Adv Exp Med Biol. 2008; 632:23-33. . View in PubMed

Pre-clinical evaluation of an sLe x-glycosylated complement inhibitory protein in a non-human primate model of reperfused stroke J Med Primatol. 2007 Dec; 36(6):375-80. . View in PubMed

Congenital pterional dermal sinus in an 18-month-old child: case report Neurosurgery. 2007 Sep; 61(3):E661; discussion E661. . View in PubMed

Early plasma complement C3a levels correlate with functional outcome after aneurysmal subarachnoid hemorrhage Neurosurgery. 2007 Aug; 61(2):255-60; discussion 260-1. . View in PubMed

Deep hypothermic circulatory arrest for complex cerebral aneurysms: lessons learned Neurosurgery. 2007 May; 60(5):815-27; discussion 815-27. . View in PubMed

Clinicoradiological review: bilateral ethmoidal artery dural arteriovenous fistulas Neurosurgery. 2007 Jan; 60(1):131-5; discussion 135-6. . View in PubMed

Ventriculoperitoneal shunting of idiopathic normal pressure hydrocephalus increases midbrain size: a potential mechanism for gait improvement Neurosurgery. 2006 Oct; 59(4):847-50; discussion 850-1. . View in PubMed

Preclinical evaluation of the neuroprotective effect of soluble complement receptor type 1 in a nonhuman primate model of reperfused stroke J Neurosurg. 2006 Oct; 105(4):595-601. . View in PubMed

A cerebroprotective dose of intravenous citrate/sorbitol-stabilized dehydroascorbic acid is correlated with increased cerebral ascorbic acid and inhibited lipid peroxidation after murine reperfused stroke Neurosurgery. 2006 Aug; 59(2):383-8; discussion 383-8. . View in PubMed

Complement component C3 mediates inflammatory injury following focal cerebral ischemia Circ Res. 2006 Jul 21; 99(2):209-17. . View in PubMed

Temporal pattern of C1q deposition after transient focal cerebral ischemia J Neurosci Res. 2006 Apr; 83(5):883-9. . View in PubMed

Racial differences in cerebral vasospasm: a systematic review of the literature Neurosurgery. 2006 Feb; 58(2):305-14. . View in PubMed

Predictors of neurocognitive decline after carotid endarterectomy Neurosurgery. 2006 05; 58(5):844-50; discussion 844-50. . View in PubMed

Galbraith Award: evaluation of risk factors associated with neurocognitive changes after carotid endarterectomy Clin Neurosurg. 2006; 53:301-6. . View in PubMed

Elevations in preoperative monocyte count predispose to acute neurocognitive decline after carotid endarterectomy for asymptomatic carotid artery stenosis Stroke. 2006 Jan; 37(1):240-2. . View in PubMed

Co-registration of radiographic and pathologic infarct territory in a non-human primate model of stroke Neurol Res. 2005 Sep; 27(6):634-7. . View in PubMed

Herniation secondary to critical postcraniotomy cerebrospinal fluid hypovolemia Neurosurgery. 2005 Aug; 57(2):286-92; discussion 286-92. . View in PubMed

Clinicopathological review: tumefactive demyelination in a 12-year-old girl Neurosurgery. 2005 May; 56(5):1051-7; discussion 1051-7. . View in PubMed

Effect of prior statin use on functional outcome and delayed vasospasm after acute aneurysmal subarachnoid hemorrhage: a matched controlled cohort study Neurosurgery. 2005 Mar; 56(3):476-84; discussion 476-84. . View in PubMed

An extramedullary foramen magnum cavernous malformation presenting with acute subarachnoid hemorrhage: case report and literature review Neurosurgery. 2005 Feb; 56(2):E410; discussion E410. . View in PubMed

Treatment of mechanically-induced vasospasm of the carotid artery in a primate using intra-arterial verapamil: a technical case report BMC Cardiovasc Disord. 2004 Jul 21; 4:11. . View in PubMed

Solitary cerebellar metastasis of malignant pleural mesothelioma: case report Surg Neurol. 2004 Feb; 61(2):174-8; discussion 178-9. . View in PubMed

A modified transorbital baboon model of reperfused stroke Methods Enzymol. 2004; 386:60-73. . View in PubMed

Serial magnetic resonance imaging in experimental primate stroke: validation of MRI for pre-clinical cerebroprotective trials Neurol Res. 2003 Dec; 25(8):846-52. . View in PubMed

Ultrarapid, convection-enhanced intravascular hypothermia: a feasibility study in nonhuman primate stroke Stroke. 2003 Aug; 34(8):1994-9. . View in PubMed

Intracranial pressure following aneurysmal subarachnoid hemorrhage: monitoring practices and outcome data Neurosurg Focus. 2003 Apr 15; 14(4):e3. . View in PubMed

An improved functional neurological examination for use in nonhuman primate studies of focal reperfused cerebral ischemia Neurol Res. 2003 Apr; 25(3):280-4. . View in PubMed

Interhemispheric intracranial pressure gradients in nonhuman primate stroke Surg Neurol. 2002 Nov; 58(5):295-301; discussion 301. . View in PubMed

Neuroprotection in cerebral ischemia by neutralization of 3-aminopropanal Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5579-84. . View in PubMed

Outcome prediction with serum intercellular adhesion molecule-1 levels after aneurysmal subarachnoid hemorrhage J Neurosurg. 2002 Jan; 96(1):71-5. . View in PubMed

Dr. Mack's major areas of clinical interest are stroke, brain aneurysms, subarachnoid hemorrhage, arteriovenous malformations (AVMs), arteriovenous fistulas, cavernous malformations, carotid artery disease, intracranial stenosis, and brain tumors. Dr. Mack performs both open surgery and minimally invasive, endovascular procedures for cerebrovascular disorders.

Dr. Mack is a faculty member of the Neuroscience Graduate Program and is the Principal Investigator and Director of the Cerebrovascular Laboratory in the Zilkha Neurogenetic Institute. He receives NIH R01 funding for his laboratory research. Dr. Mack’s scientific interests are focused on translational efforts to treat ischemic and hemorrhagic stroke. Laboratory investigations concentrate on the pathophysiology of cerebral ischemia and inflammatory modulation. Using the information and experience gained in the laboratory, Dr. Mack is working to develop new technologies, techniques, and therapies to directly improve the clinical care administered to stroke patients.

William Mack, MD, received his Bachelor degree with honors from Cornell University. He then attended Columbia University, College of Physicians and Surgeons, where he graduated from medical school (Alpha Omega Alpha) and completed Neurosurgical residency training. During residency, he spent one year performing a post-doctoral cerebrovascular research fellowship under Drs. David J. Pinsky and E. Sander Connolly Jr. at Columbia University. Following residency, Dr. Mack completed an Interventional Neuroradiology/ Neuroendovascular Surgery fellowship at UCLA.

Dr. Mack is board certified by the American Board of Neurological Surgery (FAANS) and is a fellow of the American Heart Association (FAHA) and. He is a committee member on the executive council of the Congress of Neurological Surgeons/ American Association of Neurological Surgeons’ Cerebrovascular Section. Dr. Mack serves as an Associate Editor of the Journal of Neurointerventional Surgery and on the editorial board of World Neurosurgery.
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