Yong Zhang

Dr. Zhang received his B.S. in Biological Sciences from Shandong University in 2003 and his M.S. in Biophysics from University of Guelph in 2006. He earned his Ph.D. in Biochemistry with Professor Vern L. Schramm at Albert Einstein College of Medicine in 2011. His doctoral research was focused on the enzymatic transition state and catalytic mechanism for rational design of potent enzyme inhibitors as antimalarial and anticancer drugs. Dr. Zhang received postdoctoral training with Professor Peter G. Schultz at the Scripps Research Institute and California Institute for Biomedical Research (Calibr) from 2011 to 2014. His postdoctoral work established a versatile approach to the generation of novel antibody chimeras with excellent physical, biological, and pharmacological properties for drug development. Dr. Zhang joined the faculty in the Department of Pharmacology and Pharmaceutical Sciences at USC School of Pharmacy as an Assistant Professor in December 2014.

• Discovery of an NAD+ analogue with enhanced specificity for PARP1 Chem Sci. 2022 Feb 16; 13(7):1982-1991. . View in PubMed
• Facile chemoenzymatic synthesis of a novel stable mimic of NAD Chem Sci. 2018 Nov 28; 9(44):8337-8342. . View in PubMed
• Characterization of asparagine 330 deamidation in an Fc-fragment of IgG1 using cation exchange chromatography and peptide mapping J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Aug 15; 965:65-71. . View in PubMed
• Asparagine deamidation dependence on buffer type, pH, and temperature J Pharm Sci. 2013 Jun; 102(6):1712-1723. . View in PubMed