Keck School Faculty

Yueh-Yun Chi
Yueh-Yun Chi
Associate Professor of Research Pediatrics and Preventive Medicine
Pediatrics
4640 West Sunset Boulevard Off Campus Los Angeles

Relationship between tumor response at therapy completion and prognosis in patients with Group III rhabdomyosarcoma: A report from the Children's Oncology Group Int J Cancer. 2020 Sep 01; 147(5):1419-1426. . View in PubMed

Results of Treatment for Patients With Multicentric or Bilaterally Predisposed Unilateral Wilms Tumor (AREN0534): A report from the Children's Oncology Group Cancer. 2020 Aug 01; 126(15):3516-3525. . View in PubMed

Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial Lancet Oncol. 2020 Jul 20. . View in PubMed

Outcome analysis of stage I epithelial-predominant favorable-histology Wilms tumors: A report from Children's Oncology Group study AREN03B2 Cancer. 2020 Jun 15; 126(12):2866-2871. . View in PubMed

Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee Int J Cancer. 2020 Jun 11. . View in PubMed

Maternal endothelial function, circulating endothelial cells, and endothelial progenitor cells in pregnancies conceived with or without in vitro fertilization Am J Physiol Regul Integr Comp Physiol. 2020 Jun 01; 318(6):R1091-R1102. . View in PubMed

Activity of Vincristine and Irinotecan in Diffuse Anaplastic Wilms Tumor and Therapy Outcomes of Stage II to IV Disease: Results of the Children's Oncology Group AREN0321 Study J Clin Oncol. 2020 May 10; 38(14):1558-1568. . View in PubMed

Reply to DM. Green. J Clin Oncol. 2020 Mar 01; 38(7):773-774. . View in PubMed

Imaging Characteristics of Nephrogenic Rests Versus Small Wilms Tumors: A Report From the Children's Oncology Group Study AREN03B2 AJR Am J Roentgenol. 2020 05; 214(5):987-994. . View in PubMed

Pediatr Blood Cancer. 2020 05; 67(5):e28243. . View in PubMed

An efficient integrative resampling method for gene-trait association analysis Genet Epidemiol. 2020 03; 44(2):197-207. . View in PubMed

A risk-based treatment strategy for non-rhabdomyosarcoma soft-tissue sarcomas in patients younger than 30 years (ARST0332): a Children's Oncology Group prospective study Lancet Oncol. 2020 01; 21(1):145-161. . View in PubMed

Tetralithio Metalla-aromatics with Two Independent Perpendicular Dilithio Aromatic Rings Spiro-fused by One Manganese Atom Angew Chem Int Ed Engl. 2019 Jul 08; 58(28):9625-9631. . View in PubMed

Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Oncology Group Cancer Med. 2019 10; 8(14):6437-6448. . View in PubMed

Maternal Cardiovascular Dysregulation During Early Pregnancy After In Vitro Fertilization Cycles in the Absence of a Corpus Luteum Hypertension. 2019 09; 74(3):705-715. . View in PubMed

Clinical features and outcomes of young patients with epithelioid sarcoma: an analysis from the Children's Oncology Group and the European paediatric soft tissue Sarcoma Study Group prospective clinical trials Eur J Cancer. 2019 05; 112:98-106. . View in PubMed

Increased Preeclampsia Risk and Reduced Aortic Compliance With In Vitro Fertilization Cycles in the Absence of a Corpus Luteum Hypertension. 2019 03; 73(3):640-649. . View in PubMed

Effect of Mode of Conception on Maternal Serum Relaxin, Creatinine, and Sodium Concentrations in an Infertile Population Reprod Sci. 2019 03; 26(3):412-419. . View in PubMed

Outcome of Wilms tumor patients with bone metastasis enrolled on National Wilms Tumor Studies 1-5: A report from the Children's Oncology Group Pediatr Blood Cancer. 2019 01; 66(1):e27430. . View in PubMed

Impact of cyclophosphamide and etoposide on outcome of clear cell sarcoma of the kidney treated on the National Wilms Tumor Study-5 (NWTS-5) Pediatr Blood Cancer. 2019 01; 66(1):e27450. . View in PubMed

Power and Sample Size for Fixed-Effects Inference in Reversible Linear Mixed Models Am Stat. 2019; 73(4):350-359. . View in PubMed

Augmentation of Therapy for Combined Loss of Heterozygosity 1p and 16q in Favorable Histology Wilms Tumor: A Children's Oncology Group AREN0532 and AREN0533 Study Report J Clin Oncol. 2019 10 20; 37(30):2769-2777. . View in PubMed

Randomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children's Oncology Group J Clin Oncol. 2019 11 01; 37(31):2866-2874. . View in PubMed

Increased local failure for patients with intermediate-risk rhabdomyosarcoma on ARST0531: A report from the Children's Oncology Group Cancer. 2019 09 15; 125(18):3242-3248. . View in PubMed

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor JCI Insight. 2019 08 08; 4(15). . View in PubMed

The addition of cixutumumab or temozolomide to intensive multiagent chemotherapy is feasible but does not improve outcome for patients with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group Cancer. 2019 01 15; 125(2):290-297. . View in PubMed

Potential influence of the corpus luteum on circulating reproductive and volume regulatory hormones, angiogenic and immunoregulatory factors in pregnant women Am J Physiol Endocrinol Metab. 2019 10 01; 317(4):E677-E685. . View in PubMed

Impact of Surveillance Imaging Modality on Survival After Recurrence in Patients With Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group J Clin Oncol. 2018 Oct 18; JCO1800076. . View in PubMed

Reply to DM. Green. J Clin Oncol. 2018 Sep 13; JCO1800659. . View in PubMed

First trimester pregnancy ultrasound findings as a function of method of conception in an infertile population J Assist Reprod Genet. 2018 May; 35(5):863-870. . View in PubMed

Soluble CD14, CD163, and CD27 biomarkers distinguish ART-suppressed youth living with HIV from healthy controls J Leukoc Biol. 2018 04; 103(4):671-680. . View in PubMed

Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group J Clin Oncol. 2018 09 20; 36(27):2770-2777. . View in PubMed

Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group Cancer. 2018 05 01; 124(9):1973-1981. . View in PubMed

Internal pilot design for balanced repeated measures Stat Med. 2018 02 10; 37(3):375-389. . View in PubMed

Outcome and Prognostic Factors in Stage III Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group Study AREN0532 J Clin Oncol. 2018 01 20; 36(3):254-261. . View in PubMed

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group Pediatr Blood Cancer. 2017 Dec; 64(12). . View in PubMed

Formation and ligand-based reductive chemistry of bridged bis-alkylidene scandium(iii) complexes Chem Sci. 2017 Oct 01; 8(10):6852-6856. . View in PubMed

45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group Pediatr Blood Cancer. 2017 Sep; 64(9). . View in PubMed

Patterns of chemotherapy-induced toxicities and outcome in children and adolescents with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group Pediatr Blood Cancer. 2017 Sep; 64(9). . View in PubMed

Outcome of patients with intracranial relapse enrolled on national Wilms Tumor Study Group clinical trials Pediatr Blood Cancer. 2017 Jul; 64(7). . View in PubMed

Spiro Metalla-aromatics of Pd, Pt, and Rh: Synthesis and Characterization J Am Chem Soc. 2017 Apr 12; 139(14):5039-5042. . View in PubMed

Comparison of multiple non-invasive methods of measuring cardiac output during pregnancy reveals marked heterogeneity in the magnitude of cardiac output change between women Physiol Rep. 2017 Apr; 5(8). . View in PubMed

CuOTf-Catalyzed Selective Generation of 2-Aminopyrimidines from Carbodiimides and Diaryliodonium Salts by a Triple C(sp3 )-H Functionalization Chemistry. 2017 Jan 18; 23(4):757-761. . View in PubMed

Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group Eur J Cancer. 2017 06; 78:1-6. . View in PubMed

Clinical Outcome and Biological Predictors of Relapse After Nephrectomy Only for Very Low-risk Wilms Tumor: A Report From Children's Oncology Group AREN0532 Ann Surg. 2017 04; 265(4):835-840. . View in PubMed

Dual Functionalization of White Phosphorus: Formation, Characterization, and Reactivity of Rare-Earth-Metal Cyclo-P3 Complexes Angew Chem Int Ed Engl. 2017 12 11; 56(50):15886-15890. . View in PubMed

Synthesis of Quinoline Derivatives via Cu-Catalyzed Cascade Annulation of Heterocumulenes, Alkynes, and Diaryliodonium Salts Org Lett. 2017 05 19; 19(10):2694-2697. . View in PubMed

Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group Clin Cancer Res. 2016 Nov 15; 22(22):5582-5591. . View in PubMed

Collection of pregnancy outcome records following infertility-challenges and possible solutions J Assist Reprod Genet. 2016 Aug; 33(8):993-9. . View in PubMed

A polyethylenimine functionalized porous/hollow nanoworm as a drug delivery system and a bioimaging agent Phys Chem Chem Phys. 2016 Mar 21; 18(11):7820-8. . View in PubMed

Pediatric cystic nephromas: distinctive features and frequent DICER1 mutations Hum Pathol. 2016 Feb; 48:81-7. . View in PubMed

Aromatic Dicupra[10]annulenes J Am Chem Soc. 2016 Jan 13; 138(1):60-3. . View in PubMed

Association of Chromosome 1q Gain With Inferior Survival in Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group J Clin Oncol. 2016 09 10; 34(26):3189-94. . View in PubMed

Direct Synthesis of Phospholyl Lithium from White Phosphorus Angew Chem Int Ed Engl. 2016 08 01; 55(32):9187-90. . View in PubMed

Structure and Reaction Chemistry of Magnesium Organocuprates Derived from Magnesiacyclopentadienes and Copper(I) Salts Angew Chem Int Ed Engl. 2016 11 14; 55(47):14762-14765. . View in PubMed

Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users Am J Clin Nutr. 2015 Sep; 102(3):616-25. . View in PubMed

Synthesis and Mechanistic Study of Cyclic Oxoguanidines via Zn(OTf)2 -Catalyzed Guanylation/Amidation from Readily Available Amino Acid Esters and Carbodiimides Chemistry. 2015 Jul 13; 21(29):10369-78. . View in PubMed

Frozen blastocyst embryo transfer using a supplemented natural cycle protocol has a similar live birth rate compared to a programmed cycle protocol J Assist Reprod Genet. 2015 Jul; 32(7):1057-62. . View in PubMed

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors Cancer Cell. 2015 Feb 09; 27(2):286-97. . View in PubMed

Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis Appl Environ Microbiol. 2015 Jan; 81(2):783-93. . View in PubMed

Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives on these processes J Nutr. 2015 Jan; 145(1):87-95. . View in PubMed

Low-dose adefovir dipivoxil may induce Fanconi syndrome: clinical characteristics and long-term follow-up for Chinese patients Antivir Ther. 2015; 20(6):603-11. . View in PubMed

Oxidant-switchable selective synthesis of 2-aminobenzimidazoles via C-H amination/acetoxylation of guanidines Org Lett. 2014 Dec 19; 16(24):6274-7. . View in PubMed

Substituent-controlled selective synthesis of N-acyl 2-aminothiazoles by intramolecular Zwitterion-mediated C-N bond cleavage J Org Chem. 2014 Nov 21; 79(22):11146-54. . View in PubMed

Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cells Am J Physiol Endocrinol Metab. 2014 Jul 01; 307(1):E93-101. . View in PubMed

Power calculation for overall hypothesis testing with high-dimensional commensurate outcomes Stat Med. 2014 Feb 28; 33(5):812-27. . View in PubMed

Cleavage of the C=N bond in carbodiimides via release of high ring strain: a new strategy for the selective synthesis of 2-aminoaryl alkynyl imines Chemistry. 2014 Feb 24; 20(9):2463-8. . View in PubMed

Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women J Nutr. 2013 Nov; 143(11):1719-27. . View in PubMed

Mechanistic study on the cleavage and reorganization of C(sp3)-H and C=N bonds in carbodiimides: synthesis of 1,2-dihydrothiopyrimidines and 2,3-dihydropyrimidinthiones through four-component coupling Chemistry. 2013 Aug 05; 19(32):10643-54. . View in PubMed

Confidence regions for repeated measures ANOVA power curves based on estimated covariance BMC Med Res Methodol. 2013 Apr 15; 13:57. . View in PubMed

Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjects PLoS One. 2013; 8(6):e63544. . View in PubMed

Number and function of bone-marrow derived angiogenic cells and coronary flow reserve in women without obstructive coronary artery disease: a substudy of the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) PLoS One. 2013; 8(12):e81595. . View in PubMed

Marginal vitamin B-6 deficiency decreases plasma (n-3) and (n-6) PUFA concentrations in healthy men and women J Nutr. 2012 Oct; 142(10):1791-7. . View in PubMed

Novel mutations of CYP27B1 gene lead to reduced activity of 1a-hydroxylase in Chinese patients Bone. 2012 Sep; 51(3):563-9. . View in PubMed

Bayesian influence measures for joint models for longitudinal and survival data Biometrics. 2012 Sep; 68(3):954-64. . View in PubMed

Global hypothesis testing for high-dimensional repeated measures? outcomes. Stat Med. 2012 Apr 13; 31(8):724-42.. View in PubMed

Regioselective ring expansion of 2,4-diiminoazetidines via cleavage of C-N and C(sp3)-H bonds: efficient construction of 2,3-dihydropyrimidinesulfonamides J Am Chem Soc. 2012 Feb 15; 134(6):2926-9. . View in PubMed

Repeat radiosurgery for intracranial arteriovenous malformations Neurosurgery. 2012 Jan; 70(1):150-4; discussion 154. . View in PubMed

Radiographic response of brain metastasis after linear accelerator radiosurgery Stereotact Funct Neurosurg. 2012; 90(2):69-78. . View in PubMed

Incidence of ventricular shunt placement for hydrocephalus with clipping versus coiling for ruptured and unruptured cerebral aneurysms in the Nationwide Inpatient Sample database: 2002 to 2007 World Neurosurg. 2011 Dec; 76(6):548-54. . View in PubMed

Incidence of seizures or epilepsy after clipping or coiling of ruptured and unruptured cerebral aneurysms in the nationwide inpatient sample database: 2002-2007 Neurosurgery. 2011 Sep; 69(3):644-50; discussion 650. . View in PubMed

Stent-associated flow remodeling causes further occlusion of incompletely coiled aneurysms Neurosurgery. 2011 Sep; 69(3):598-603; discussion 603-4. . View in PubMed

Linear accelerator radiosurgery for nonvestibular schwannomas Neurosurgery. 2011 Apr; 68(4):974-84; discussion 984. . View in PubMed

Effect of weekend compared with weekday stroke admission on thrombolytic use, in-hospital mortality, discharge disposition, hospital charges, and length of stay in the Nationwide Inpatient Sample Database, 2002 to 2007 Stroke. 2010 Oct; 41(10):2323-8. . View in PubMed

Relationship between higher rates of adverse events in deep brain stimulation using standardized prospective recording and patient outcomes Neurosurg Focus. 2010 Aug; 29(2):E4. . View in PubMed

Identification and preliminary characterization of ubiquitin C terminal hydrolase 1 (UCHL1) as a biomarker of neuronal loss in aneurysmal subarachnoid hemorrhage J Neurosci Res. 2010 May 15; 88(7):1475-84. . View in PubMed

Length of stay and total hospital charges of clipping versus coiling for ruptured and unruptured adult cerebral aneurysms in the Nationwide Inpatient Sample database 2002 to 2006 Stroke. 2010 Feb; 41(2):337-42. . View in PubMed

Rapid fabrication of custom patient biopsy guides J Appl Clin Med Phys. 2009 Sep 02; 10(4):2897. . View in PubMed

The linkage between pediatric quality of life and health conditions: establishing clinically meaningful cutoff scores for the PedsQL Value Health. 2009 Jul-Aug; 12(5):773-81. . View in PubMed

Factors associated with aspirin resistance in patients premedicated with aspirin and clopidogrel for endovascular neurosurgery Neurosurgery. 2009 May; 64(5):890-5; discussion 895-6. . View in PubMed

The effect of coiling versus clipping of ruptured and unruptured cerebral aneurysms on length of stay, hospital cost, hospital reimbursement, and surgeon reimbursement at the university of Florida Neurosurgery. 2009 Apr; 64(4):614-9; discussion 619-21. . View in PubMed

Linear accelerator radiosurgery for cavernous sinus meningiomas Stereotact Funct Neurosurg. 2009; 87(2):120-7. . View in PubMed

Lower incidence of reoperation with longer shunt survival with adult ventriculoperitoneal shunts placed for hemorrhage-related hydrocephalus Neurosurgery. 2008 Jul; 63(1):70-4; discussion 74-5. . View in PubMed

Conjugal Alzheimer disease: risk in children when both parents have Alzheimer disease Arch Neurol. 2008 Mar; 65(3):373-8. . View in PubMed

A new class of mixture models for differential gene expression in DNA microarray data J Stat Plan Inference. 2008 Feb 01; 138(2):387-404. . View in PubMed

The need for reorientation toward cost-effective prediction: comments on 'Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond' by Pencina et al, Statistics in Medicine (DOI: 10. 1002/sim. 2929). Stat Med. 2008 Jan 30; 27(2):182-4. . View in PubMed

Bayesian hierarchical modeling for time course microarray experiments Biometrics. 2007 Jun; 63(2):496-504. . View in PubMed

Joint models for multivariate longitudinal and multivariate survival data Biometrics. 2006 Jun; 62(2):432-45. . View in PubMed

Comparison of human and automatic segmentations of kidneys from CT images Int J Radiat Oncol Biol Phys. 2005 Mar 01; 61(3):954-60. . View in PubMed

Symptom patterns and subgrouping of schizophrenic patients: significance of negative symptoms assessed on admission Schizophr Res. 2002 Jul 01; 56(1-2):105-19. . View in PubMed

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