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Zhilei Shen, PhD

Business Title Assistant Professor Of Clinical Radiation Oncology

Lead, Medical Physics Treatment Planning and Information Technology

Physics Clinical Operations Co-Director

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Email [email protected]
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Overview

Dr. Zhilei (Julie) Shen is an Assistant Professor of Clinical Radiation Oncology-Medical Physics at USC Norris Cancer Hospital and USC + Los Angeles County Medical Center. She joined USC in November 2019.

Dr. Zhilei (Julie) Shen graduated from Southeast University in Nanjing, China with a Bachelor of Engineering degree in Biomedical Engineering. She received her doctorate degree in Biomedical Engineering from Case Western Reserve University and completed her residency in medical physics at Cleveland Clinic in 2016.

After completing her residency, Dr. Shen became a clinical assistant professor at University of Pittsburgh Medical Center (UPMC) specializing in medical physics. Dr. Shen has presented and published in multiple areas including biomaterials, biomechanics, ultrasound imaging, medical physics, and medical dosimetry. Her research interests include advanced treatment planning, deformable image registration, and image-guided radiation therapy.

Medical Physics Expertise: Treatment Planning, SRS/SBRT, Gamma Knife, IGRT, DIBH, 4DCT, TBI, TSET, HDR, LDR

Languages Spoken: English and Chinese (Mandarin)

Publications

  • Survey of work-from-home experiences among medical physicists in Southern California during and after the COVID-19 pandemic. J Appl Clin Med Phys. 2026 Mar; 27(3):e70523.. View in PubMed
  • Tomotherapy-based stereotactic radiosurgery and stereotactic body radiation therapy. J Radiosurg SBRT. 2026; 10(1-2):23-31.. View in PubMed
  • Stereotactic core ablative radiation therapy for small hypoxic tumors: impact of dosimetric approaches and consequent optimization strategy in the context of spatially fractionated radiation therapy. Front Oncol. 2025; 15:1568959.. View in PubMed
  • Therapeutic medical physicist well-being and employment satisfaction during the COVID-19 pandemic in California. J Appl Clin Med Phys. 2025 Sep; 26(9):e70233.. View in PubMed
  • Dosimetric characterization for GRID collimator-based spatially fractionated radiation therapy: Dosimetric parameter acquisition and machine interchangeability investigation. J Appl Clin Med Phys. 2024 Aug; 25(8):e14410.. View in PubMed
  • A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests. Med Phys. 2024 Mar; 51(3):2334-2344.. View in PubMed
  • Hippocampal sparing radiation therapy for brain metastases: treatment techniques and clinical implementation. Chin Clin Oncol. 2023 Oct; 12(5):56.. View in PubMed
  • Radiation therapy practice changes in the COVID-19 pandemic era: A pilot study in California. J Appl Clin Med Phys. 2022 Nov; 23(11):e13770.. View in PubMed
  • Automatic segmentation of high-risk clinical target volume for tandem-and-ovoids brachytherapy patients using an asymmetric dual-path convolutional neural network. Med Phys. 2022 Mar; 49(3):1712-1722.. View in PubMed
  • Surviving Over a Decade With Glioblastoma: A Clinical Course Characterized by Multiple Recurrences, Numerous Salvage Treatments, and Novel Use of Cesium-131 Tiles. Cureus. 2021 Nov; 13(11):e19573.. View in PubMed

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