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Alicia A. McDonough, PhD, FAHA
Professor of Integrative Anatomical Sciences
Integrative Anatomical Sciences
MMR 508 1333 San Pablo Street Health Sciences Campus Los Angeles
+1 323 442 1238


Alicia McDonough, PhD, FAHA, is a research scientists in the field of cardiorenal physiology and hypertension. Her work epitomizes that of a classical renal physiologist scientist whose basic and translational research has been driven by challenging our understanding of the role of the kidney in the maintenance of electrolyte homeostasis and control of blood pressure in the human body. Her contributions are represented by more than 120 peer reviewed scientific studies.

Currently a Professor of Integrative Anatomical Sciences, Keck School of Medicine of USC in Los Angeles, CA, she earned degrees in Physiology at UC Berkeley (AB) and at the University of Hawaii (PhD), and was trained in molecular Physiology at UC San Francisco Cardiovascular Research Institute and Columbia University. She joined USC in 1981 where she became Professor in 1996. Initially, her lab focused on assembly of sodium pump subunits and mechanisms controlling their function in which she defined the molecular mechanisms of sodium pump regulation in kidney, cardiac and skeletal muscle by potassium, hormones, and other factors under normal conditions and during human heart failure.

Subsequently, the McDonough laboratory turned their attention to determining the renal mechanisms responsible for regulation of sodium and potassium balance as well as blood pressure. They discovered that changes in blood pressure or AngII provoked rapid trafficking of renal sodium transporters between membrane domains, as well as phosphorylation and pool size regulation. Using the transporter profiling approach to investigate renal transporters’ abundance, distribution, phosphorylation and activity along the entire nephron, Dr. McDonough and her colleagues have recently defined how stimuli such as dietary salts, Ang II, kidney injury, and cytokines increase renal sodium transport and how the resultant hypertension provokes intrarenal responses to decrease sodium reabsorption (via pressure natriuresis), a response that defines the blood pressure set point in the kidney. Currently, funded by the NIH and AHA, they are using this approach to investigate sexual dimorphisms in the female vs. male nephron and what they reveal about the cardiovascular disease protection evident in females. These projects have engaged the McDonough lab with expert collaborators across the USA and around the world, and attracted attention to the important role of the kidney in regulation of blood pressure.

Dr. McDonough is a recipient of multiple Awards including an American Heart Association (AHA) Established Investigator Award (1984), the 2009 Starling Distinguished Lectureship from the American Physiological Society (APS), and the 2014 Donald Seldin Lectureship from the AHA Council on the Kidney in Cardiovascular Disease (KCVD). She was also selected to give the 2010 Suk Ki Hong Memorial Lecture at SUNY Buffalo, the 2015 Rudy Clarenberg Distinguished Lecture at Kansas State University, and the J.J. Smith Memorial Lecture at Medical College of Wisconsin. She was the keynote speaker at the Annual Young Investigator Symposium during American Society of Nephrology (ASN) Kidney Week in 2016, and is slated to deliver the Robert Schrier Lecture at ASN Kidney week, 2017, and the Steven Hebert Award for the American Physiological Society in 2018. Alicia McDonough is also highly committed to various services for the research community. She actively contributes to APS, AHA and ASN committees, grant reviews and editorial boards. She also served on multiple study sections for NIH, VA, AHA and other national and international agencies. Importantly, she has demonstrated commitment to training and mentoring the next generation of medical and PhD students, postdoctoral fellows and junior faculty.


American Physiological Society Epithelial Transport Group: Steve Hebert Lecturer, 2018

American Society of Nephrology: Robert W. Schrier Endowed Lectureship, 2017

Medical College of Wisconsin: J.J. Smith Endowed Lecture, 2016

KCVD Young Investigator Symposium: Keynote Speaker ANS Kidney Week, 2016

Kansas State Univ. Veterinary Medicine: Clarenberg Distinguished Lecture, 2015

AHA Kidney in Cardiovascular Disease Council: Donald Seldin Lecture, 2014

SUNY Buffalo: Suk Ki Hong Memorial Lecturer, 2010

American Physiological Society: Ernest H. Starling Distinguished Lectureship, 2009

Keck School of Medicine: Outstanding Teaching Award, 2007-2012

American Heart Association: Established Investigator Award, 1984-1989


. Functional Implications of Sexual Dimorphism of Transporter Patterns along the Rat Proximal Tubule: Modeling and Analysis Am J Physiol Renal Physiol. 2018 May 30. View in: PubMed

. Blood pressure regulation by the angiotensin type 1 receptor in the proximal tubule Curr Opin Nephrol Hypertens. 2018 01; 27(1):1-7. View in: PubMed

. Downregulation of the Cl-/HCO3-Exchanger Pendrin in Kidneys of Mice with Cystic Fibrosis: Role in the Pathogenesis of Metabolic Alkalosis Cell Physiol Biochem. 2018; 45(4):1551-1565. View in: PubMed

. Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice Am J Physiol Renal Physiol. 2017 Dec 01; 313(6):F1243-F1253. View in: PubMed

. Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis J Am Soc Nephrol. 2017 Dec; 28(12):3504-3517. View in: PubMed

. Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways J Am Heart Assoc. 2017 Oct 24; 6(10). View in: PubMed

. Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II J Am Soc Nephrol. 2017 Jun; 28(6):1826-1837. View in: PubMed

. Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits Physiology (Bethesda). 2017 Mar; 32(2):100-111. View in: PubMed

. Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity Kidney Int. 2017 04; 91(4):856-867. View in: PubMed

. Cardiovascular benefits associated with higher dietary K+ vslower dietary Na+: evidence from population and mechanistic studies. Am J Physiol Endocrinol Metab. 2017 04 01; 312(4):E348-E356. View in: PubMed

. ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure-Hypertension and the Proximal Tubule Kidney Int Rep. 2016 Sep; 1(3):166-176. View in: PubMed

. Paracellular epithelial sodium transport maximizes energy efficiency in the kidney J Clin Invest. 2016 Jul 01; 126(7):2509-18. View in: PubMed

. Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron Cell Metab. 2016 Feb 09; 23(2):360-8. View in: PubMed

. The physiological role of glucagon-like peptide-1 in the regulation of renal function Am J Physiol Renal Physiol. 2016 Jan 15; 310(2):F123-7. View in: PubMed

. Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension Hypertension. 2016 10; 68(4):904-12. View in: PubMed

. Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension Hypertension. 2016 07; 68(1):167-74. View in: PubMed

. Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling Am J Physiol Cell Physiol. 2015 Oct 15; 309(8):C541-50. View in: PubMed

. Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron Physiol Rep. 2015 Sep; 3(9). View in: PubMed

. Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme Hypertension. 2015 Sep; 66(3):534-42. View in: PubMed

. Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension Hypertension. 2015 Sep; 66(3):450-5. View in: PubMed

. Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention Am J Physiol Renal Physiol. 2015 Jul 01; 309(1):F63-70. View in: PubMed

. The intrarenal generation of angiotensin II is required for experimental hypertension Curr Opin Pharmacol. 2015 Apr; 21:73-81. View in: PubMed

. Considerations when quantitating protein abundance by immunoblot Am J Physiol Cell Physiol. 2015 Mar 15; 308(6):C426-33. View in: PubMed

. Hypertension. 2015 Mar; 65(3):569-76. View in: PubMed

. Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2 Physiol Rep. 2014 Dec 01; 2(12). View in: PubMed

. Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition J Am Soc Nephrol. 2014 Dec; 25(12):2752-63. View in: PubMed

. Am J Physiol Renal Physiol. 2014 Dec 01; 307(11):F1249-62. View in: PubMed

. Of mice and men: modeling cardiovascular complexity in diabetesFocus on "Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart". Am J Physiol Cell Physiol. 2014 Sep 15; 307(6):C497-8. View in: PubMed

. Renal generation of angiotensin II and the pathogenesis of hypertension Curr Hypertens Rep. 2014 Sep; 16(9):477. View in: PubMed

. Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1059-68. View in: PubMed

. Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition Am J Physiol Renal Physiol. 2013 Aug 15; 305(4):F510-9. View in: PubMed

. J Mol Med (Berl). 2013 Aug; 91(8):951-63. View in: PubMed

. The absence of intrarenal ACE protects against hypertension J Clin Invest. 2013 May; 123(5):2011-23. View in: PubMed

. Need to quickly excrete K(+)? Turn off NCC. Kidney Int. 2013 May; 83(5):779-82. View in: PubMed

. Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties Am J Physiol Cell Physiol. 2013 Jan 15; 304(2):C147-63. View in: PubMed

. Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron Am J Physiol Renal Physiol. 2012 Jul 01; 303(1):F92-104. View in: PubMed

. Am J Physiol Cell Physiol. 2012 May 15; 302(10):C1434-5. View in: PubMed

. How does potassium supplementation lower blood pressure? Am J Physiol Renal Physiol. 2012 May 01; 302(9):F1224-5. View in: PubMed

. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure Cell Metab. 2011 Apr 06; 13(4):469-475. View in: PubMed

. Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure Am J Physiol Regul Integr Comp Physiol. 2010 Apr; 298(4):R851-61. View in: PubMed

. Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli Am J Physiol Renal Physiol. 2010 Jan; 298(1):F177-86. View in: PubMed

. Motoring down the microvilliFocus on "PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI". Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1331-2. View in: PubMed

. Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1 Eur J Pharmacol. 2009 Nov 10; 622(1-3):7-14. View in: PubMed

. Narrative review: evolving concepts in potassium homeostasis and hypokalemia Ann Intern Med. 2009 May 05; 150(9):619-25. View in: PubMed

. Renal NHE3 and NaPi2 partition into distinct membrane domains Am J Physiol Cell Physiol. 2009 Apr; 296(4):C900-10. View in: PubMed

. Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles Am J Physiol Renal Physiol. 2009 Apr; 296(4):F810-8. View in: PubMed

. Recent advances in understanding integrative control of potassium homeostasis Annu Rev Physiol. 2009; 71:381-401. View in: PubMed

. Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status Am J Physiol Renal Physiol. 2008 Oct; 295(4):F1003-16. View in: PubMed

. Connexin 303 is expressed in the kidney but not regulated by dietary salt or high blood pressure. Cell Commun Adhes. 2008 May; 15(1):219-30. View in: PubMed

. Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule Am J Nephrol. 2008; 28(2):330-8. View in: PubMed

. AMPK activation with AICAR provokes an acute fall in plasma [K+] Am J Physiol Cell Physiol. 2008 Jan; 294(1):C126-35. View in: PubMed

. Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1197-208. View in: PubMed

. ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membrane Am J Physiol Renal Physiol. 2007 Sep; 293(3):F662-9. View in: PubMed

. Evidence for gut factor in K+ homeostasis Am J Physiol Renal Physiol. 2007 Aug; 293(2):F541-7. View in: PubMed

. Redistribution of distal tubule Na+-Cl- cotransporter (NCC) in response to a high-salt diet Am J Physiol Renal Physiol. 2006 Aug; 291(2):F503-8. View in: PubMed

. The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response J Pediatr Gastroenterol Nutr. 2006 Jul; 43 Suppl 1:S74-81. View in: PubMed

. Phenol injury-induced hypertension stimulates proximal tubule Na+/H+ exchanger activity Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1543-50. View in: PubMed

. Modest dietary K+ restriction provokes insulin resistance of cellular K+ uptake and phosphorylation of renal outer medulla K+ channel without fall in plasma K+ concentration Am J Physiol Cell Physiol. 2006 May; 290(5):C1355-63. View in: PubMed

. Effects of ACE inhibition on proximal tubule sodium transport Am J Physiol Renal Physiol. 2006 Apr; 290(4):F854-63. View in: PubMed

. Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertension J Am Soc Nephrol. 2005 Oct; 16(10):2890-6. View in: PubMed

. Role of muscle in regulating extracellular [K+] Semin Nephrol. 2005 Sep; 25(5):335-42. View in: PubMed

. Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vsNaPi2 to endosomes. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F896-906. View in: PubMed

. Dexamethasone treatment causes resistance to insulin-stimulated cellular potassium uptake in the rat Am J Physiol Cell Physiol. 2004 Nov; 287(5):C1229-37. View in: PubMed

. Acute hypotension induced by aortic clamp vsPTH provokes distinct proximal tubule Na+ transporter redistribution patterns. Am J Physiol Regul Integr Comp Physiol. 2004 Oct; 287(4):R878-85. View in: PubMed

. Does membrane trafficking play a role in regulating the sodium/hydrogen exchanger isoform 3 in the proximal tubule? Curr Opin Nephrol Hypertens. 2003 Sep; 12(5):533-41. View in: PubMed

. Chronic renal injury-induced hypertension alters renal NHE3 distribution and abundance Am J Physiol Renal Physiol. 2003 May; 284(5):F1056-65. View in: PubMed

. Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport Ann N Y Acad Sci. 2003 Apr; 986:669-77. View in: PubMed

. Modest K+ restriction provokes insulin resistance of cellular K+ uptake without decrease in plasma K Ann N Y Acad Sci. 2003 Apr; 986:625-7. View in: PubMed

. Responses of proximal tubule sodium transporters to acute injury-induced hypertension Am J Physiol Renal Physiol. 2003 Feb; 284(2):F313-22. View in: PubMed

. Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension Am J Physiol Renal Physiol. 2002 Nov; 283(5):F1142-50. View in: PubMed

. Diuretic response to acute hypertension is blunted during angiotensin II clamp Am J Physiol Regul Integr Comp Physiol. 2002 Oct; 283(4):R837-42. View in: PubMed

. Skeletal muscle regulates extracellular potassium Am J Physiol Renal Physiol. 2002 Jun; 282(6):F967-74. View in: PubMed

. Independent regulation of in vivo insulin action on glucose versus K(+) uptake by dietary fat and K(+) content Diabetes. 2002 Apr; 51(4):915-20. View in: PubMed

. Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity Am J Physiol Renal Physiol. 2002 Apr; 282(4):F730-40. View in: PubMed

. Sodium pump isoform expression in heart failure: implication for treatment Basic Res Cardiol. 2002; 97 Suppl 1:I25-30. View in: PubMed

. The cardiac sodium pump: structure and function Basic Res Cardiol. 2002; 97 Suppl 1:I19-24. View in: PubMed

. Downstream shift in sodium pump activity along the nephron during acute hypertension J Am Soc Nephrol. 2001 Nov; 12(11):2231-40. View in: PubMed

. All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1336-43. View in: PubMed

. Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1355-64. View in: PubMed

. UT-A urea transporter protein in heart: increased abundance during uremia, hypertension, and heart failure Circ Res. 2001 Jul 20; 89(2):139-45. View in: PubMed

. Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart--right atrium vs left ventricle Cell Mol Biol (Noisy-le-grand). 2001 Mar; 47(2):373-81. View in: PubMed

. Glucocorticoids increase sodium pump alpha(2)- and beta(1)-subunit abundance and mRNA in rat skeletal muscle Am J Physiol Cell Physiol. 2001 Mar; 280(3):C509-16. View in: PubMed

. Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp Am J Physiol Renal Physiol. 2001 Jan; 280(1):F95-F102. View in: PubMed

. Proximal tubule Na transporter responses are the same during acute and chronic hypertension Am J Physiol Renal Physiol. 2000 Aug; 279(2):F358-69. View in: PubMed

. Developmental change in Na,K-ATPase alpha1 and beta1 expression in normal and hypothyroid rat renal cortex Am J Nephrol. 2000 May-Jun; 20(3):225-31. View in: PubMed

. Molecular mechanisms of sodium transport inhibition in proximal tubule during acute hypertension Curr Opin Nephrol Hypertens. 2000 Mar; 9(2):149-56. View in: PubMed

. Temporal responses of oxidative vsglycolytic skeletal muscles to K+ deprivation: Na+ pumps and cell cations. Am J Physiol. 1999 Jun; 276(6 Pt 1):C1411-9. View in: PubMed

. In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition Am J Physiol. 1999 May; 276(5 Pt 2):F711-9. View in: PubMed

. Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure Circulation. 1999 Apr 27; 99(16):2105-12. View in: PubMed

. Am J Physiol. 1998 Nov; 275(5 Pt 1):C1179-81. View in: PubMed

. Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension Am J Physiol. 1998 Oct; 275(4 Pt 2):F565-75. View in: PubMed

. The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension J Am Soc Nephrol. 1998 Apr; 9(4):531-7. View in: PubMed

. Reversible effects of acute hypertension on proximal tubule sodium transporters Am J Physiol. 1998 Apr; 274(4 Pt 1):C1090-100. View in: PubMed

. Posttranscriptional upregulation of Na(+)-K(+)-ATPase activity in newborn guinea pig renal cortex Am J Physiol. 1997 Aug; 273(2 Pt 2):F254-63. View in: PubMed

. Skeletal muscle Na,K-ATPase alpha and beta subunit protein levels respond to hypokalemic challenge with isoform and muscle type specificity J Biol Chem. 1996 Dec 20; 271(51):32653-8. View in: PubMed

. Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heart J Clin Invest. 1996 Oct 01; 98(7):1650-8. View in: PubMed

. Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis Am J Physiol. 1996 Jun; 270(6 Pt 2):F1004-14. View in: PubMed

. Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes Am J Physiol. 1996 Apr; 270(4 Pt 1):C1221-7. View in: PubMed

. Role of skeletal muscle sodium pumps in the adaptation to potassium deprivation Acta Physiol Scand. 1996 Mar; 156(3):295-304. View in: PubMed

. Renal Na+/H+ exchanger isoforms and their regulation by thyroid hormone Am J Physiol. 1996 Feb; 270(2 Pt 1):C585-92. View in: PubMed

. Reciprocal regulation of cardiac Na-K-ATPase and Na/Ca exchanger: hypertension, thyroid hormone, development Am J Physiol. 1995 Sep; 269(3 Pt 1):C675-82. View in: PubMed

. Significance of sodium pump isoforms in digitalis therapy J Mol Cell Cardiol. 1995 Apr; 27(4):1001-9. View in: PubMed

. Expression of Na(+)-K(+)-ATPase alpha- and beta-subunits along rat nephron: isoform specificity and response to hypokalemia Am J Physiol. 1994 Oct; 267(4 Pt 1):C901-8. View in: PubMed

. Amiodarone decreases Na,K-ATPase alpha 2 and beta 2 expression specifically in cardiac ventricle J Mol Cell Cardiol. 1994 Apr; 26(4):417-24. View in: PubMed

. Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats Biochem Biophys Res Commun. 1994 Mar 30; 199(3):1422-7. View in: PubMed

. Surface and intracellular pools of Na,K-ATPase catalytic and immuno-activities in rat exorbital lacrimal gland Exp Eye Res. 1993 Oct; 57(4):403-13. View in: PubMed

. Surplus Na+ pumps: how low-K(+)-incubated LLC-PK1 cells respond to K+ restoration Am J Physiol. 1993 Oct; 265(4 Pt 1):C887-92. View in: PubMed

. Thyroid hormone specifically regulates skeletal muscle Na(+)-K(+)-ATPase alpha 2- and beta 2-isoforms Am J Physiol. 1993 Sep; 265(3 Pt 1):C680-7. View in: PubMed

. Regulation of Na,K-ATPase activity Curr Opin Nephrol Hypertens. 1993 Sep; 2(5):725-34. View in: PubMed

. Na(+)-K(+)-ATPase alpha 1- and beta 1-subunit degradation: evidence for multiple subunit specific rates Am J Physiol. 1993 Mar; 264(3 Pt 1):C583-90. View in: PubMed

. Physiologic rationale for multiple sodium pump isoformsDifferential regulation of alpha 1 vs alpha 2 by ionic stimuli. Ann N Y Acad Sci. 1992 Nov 30; 671:156-68; discussion 168-9. View in: PubMed

. Low K+ increases Na(+)-K(+)-ATPase alpha- and beta-subunit mRNA and protein abundance in cultured renal proximal tubule cells Am J Physiol. 1992 Aug; 263(2 Pt 1):C436-42. View in: PubMed

. Thyroid hormone induction of rat myocardial Na(+)-K(+)-ATPase: alpha 1-, alpha 2-, and beta 1-mRNA and -protein levels at steady state Am J Physiol. 1992 Feb; 262(2 Pt 1):C484-92. View in: PubMed

. Synthesis and translocation of Na(+)-K(+)-ATPase alpha- and beta-subunits to plasma membrane in MDCK cells Am J Physiol. 1992 Feb; 262(2 Pt 1):C470-83. View in: PubMed

. Differential regulation of sodium pump isoforms in heart Semin Nephrol. 1992 Jan; 12(1):49-55. View in: PubMed

. Hypokalemia decreases Na(+)-K(+)-ATPase alpha 2- but not alpha 1-isoform abundance in heart, muscle, and brain Am J Physiol. 1991 May; 260(5 Pt 1):C958-64. View in: PubMed

. Low K+ increases Na,K-ATPase abundance in LLC-PK1/Cl4 cells by differentially increasing beta, and not alpha, subunit mRNA J Biol Chem. 1990 Oct 15; 265(29):17935-40. View in: PubMed

. Differential regulation of Na,K-ATPase alpha 1, alpha 2, and beta subunit mRNA and protein levels by thyroid hormone J Biol Chem. 1990 Aug 25; 265(24):14308-14. View in: PubMed

. Ionic regulation of the biosynthesis of NaK-ATPase subunits Semin Nephrol. 1990 Jul; 10(4):400-9. View in: PubMed

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