Arthur W. Toga, PhD

Dr. Toga is interested in the development of new algorithms and the computer science aspects important to neuroimaging. New visualization techniques and statistical measurement are employed in the study of morphometric variability in humans, subhuman primates and rodents.

His laboratory (Laboratory of Neuro Imaging) has been working on the creation of three dimensional digital neuroanatomic and functional neuroanatomic atlases for stereotactic localization and multisubject comparison. Specific programs include the development of local deformation techniques to equate brain data sets from different modalities and different subjects and the development of electronic data bases for the archival, interaction and distribution of brain data.

• The genetic architecture of multimodal human brain age Nat Commun. 2024 Mar 23; 15(1):2604. . View in PubMed
• Evaluation of ATNPD Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease Neurology. 2024 Feb; 102(4):e208033. . View in PubMed
• Anxiety in late-life depression: Associations with brain volume, amyloid beta, white matter lesions, cognition, and functional ability Int Psychogeriatr. 2024 Jan 25; 1-12. . View in PubMed
• The Alzheimer’s Disease Neuroimaging Initiative in the era of Alzheimer’s disease treatment: A review of ADNI studies from 2021 to 2022 Alzheimers Dement. 2024 Jan; 20(1):652-694. . View in PubMed
• Spatiotemporal patterns of cortical microstructural maturation in children and adolescents with diffusion MRI Hum Brain Mapp. 2024 Jan; 45(1):e26528. . View in PubMed
• Five dominant dimensions of brain aging are identified via deep learning: associations with clinical, lifestyle, and genetic measures medRxiv. 2023 Dec 30. . View in PubMed
• Relationship of Hoarding and Depression Symptoms in Older Adults Am J Geriatr Psychiatry. 2023 Nov 23. . View in PubMed
• Brain age predicted using graph convolutional neural network explains neurodevelopmental trajectory in preterm neonates Eur Radiol. 2023 Nov 14. . View in PubMed
• Comparison of genetic and health risk factors for mild cognitive impairment and Alzheimer’s disease between Hispanic and non-Hispanic white participants Alzheimers Dement. 2023 Nov; 19(11):5086-5094. . View in PubMed
• The Genetic Architecture of Multimodal Human Brain Age bioRxiv. 2023 Sep 30. . View in PubMed
• A Comparison of Neuroelectrophysiology Databases ArXiv. 2023 Aug 30. . View in PubMed
• Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability medRxiv. 2023 Aug 24. . View in PubMed
• Life After Mild Traumatic Brain Injury: Widespread Structural Brain Changes Associated With Psychological Distress Revealed With Multimodal Magnetic Resonance Imaging Biol Psychiatry Glob Open Sci. 2023 Jul; 3(3):374-385. . View in PubMed
• The Genetic Architecture of Biological Age in Nine Human Organ Systems medRxiv. 2023 Jun 17. . View in PubMed
• Correction: Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE Mol Psychiatry. 2023 Apr; 28(4):1827. . View in PubMed
• Spatiotemporal patterns of cortical microstructural maturation in children and adolescents with diffusion MRI bioRxiv. 2023 Mar 31. . View in PubMed
• Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRß, a marker of blood brain barrier breakdown, in older adults Res Sq. 2023 Mar 07. . View in PubMed
• White matter hyperintensities are higher among early-onset Alzheimer’s disease participants than their cognitively normal and early-onset nonAD peers: Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) Alzheimers Dement. 2023 11; 19 Suppl 9:S89-S97. . View in PubMed
• Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer’s disease Alzheimers Dement. 2023 11; 19 Suppl 9:S29-S41. . View in PubMed
• Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) Alzheimers Dement. 2023 11; 19 Suppl 9:S98-S114. . View in PubMed
• Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer’s Disease Study Alzheimers Dement. 2023 11; 19 Suppl 9:S115-S125. . View in PubMed
• Sex and APOE e4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer’s disease Alzheimers Dement. 2023 11; 19 Suppl 9:S49-S63. . View in PubMed
• Pathogenic variants in the Longitudinal Early-onset Alzheimer’s Disease Study cohort Alzheimers Dement. 2023 11; 19 Suppl 9:S64-S73. . View in PubMed
• Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early-Onset Alzheimer’s Disease Study (LEADS) cohort Alzheimers Dement. 2023 11; 19 Suppl 9:S42-S48. . View in PubMed
• Profiling baseline performance on the Longitudinal Early-Onset Alzheimer’s Disease Study (LEADS) cohort near the midpoint of data collection Alzheimers Dement. 2023 11; 19 Suppl 9:S8-S18. . View in PubMed
• The Sporadic Early-onset Alzheimer’s Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) Cohort Alzheimers Dement. 2023 11; 19 Suppl 9:S74-S88. . View in PubMed
• Sex differences in regional gray matter density in pre-adolescent binge eating disorder: a voxel-based morphometry study Psychol Med. 2023 10; 53(13):6077-6089. . View in PubMed
• Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum Ann Neurol. 2023 10; 94(4):632-646. . View in PubMed
• Exaggerated High-Beta Oscillations are Associated with Cortical Thinning at the Motor Cortex in Parkinson’s Disease Annu Int Conf IEEE Eng Med Biol Soc. 2023 07; 2023:1-4. . View in PubMed
• Aberrant functional connectivity between reward and inhibitory control networks in pre-adolescent binge eating disorder Psychol Med. 2023 07; 53(9):3869-3878. . View in PubMed
• Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia Alzheimers Dement. 2023 07; 19(7):2842-2852. . View in PubMed
• Weakly supervised perivascular spaces segmentation with salient guidance of Frangi filter Magn Reson Med. 2023 06; 89(6):2419-2431. . View in PubMed
• Brain structure and allelic associations in Alzheimer’s disease CNS Neurosci Ther. 2023 04; 29(4):1034-1048. . View in PubMed
• Functional connectivity alterations in traumatic brain injury patients with late seizures Neurobiol Dis. 2023 04; 179:106053. . View in PubMed
• Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE Mol Psychiatry. 2023 04; 28(4):1813-1826. . View in PubMed
• Optimizing quantification of MK6240 tau PET in unimpaired older adults Neuroimage. 2023 01; 265:119761. . View in PubMed
• Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer’s Disease Neuroimaging Initiative 4 Alzheimers Dement. 2023 01; 19(1):307-317. . View in PubMed
• The association between white matter hyperintensities and amyloid and tau deposition Neuroimage Clin. 2023; 38:103383. . View in PubMed
• Deep phenotyping and genomic data from a nationally representative study on dementia in India Sci Data. 2023 01 20; 10(1):45. . View in PubMed
• A comparison of neuroelectrophysiology databases Sci Data. 2023 10 19; 10(1):719. . View in PubMed
• Manual lesion segmentations for traumatic brain injury characterization Front Neuroimaging. 2023; 2:1068591. . View in PubMed
• The pursuit of approaches to federate data to accelerate Alzheimer’s disease and related dementia research: GAAIN, DPUK, and ADDI Front Neuroinform. 2023; 17:1175689. . View in PubMed
• Brain perivascular space imaging across the human lifespan Neuroimage. 2023 05 01; 271:120009. . View in PubMed
• The image and data archive at the laboratory of neuro imaging Front Neuroinform. 2023; 17:1173623. . View in PubMed
• Data Archive for the BRAIN Initiative (DABI) Sci Data. 2023 02 09; 10(1):83. . View in PubMed
• Mapping frontoinsular cortex from diffusion microstructure Cereb Cortex. 2023 03 10; 33(6):2715-2733. . View in PubMed
• Investigating the factors that explain white matter hyperintensity load in older Indians Brain Commun. 2023; 5(1):fcad008. . View in PubMed
• A quantitative characterization of the spatial distribution of brain metastases from breast cancer and respective molecular subtypes J Neurooncol. 2022 Oct; 160(1):241-251. . View in PubMed
• Corrigendum to “Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla” [NeuroImage volume 245, 2021, 118724] Neuroimage. 2022 Apr 15; 250:118921. . View in PubMed
• Imaging subtle leaks in the blood-brain barrier in the aging human brain: potential pitfalls, challenges, and possible solutions Geroscience. 2022 06; 44(3):1339-1351. . View in PubMed
• Regional gray matter abnormalities in pre-adolescent binge eating disorder: A voxel-based morphometry study Psychiatry Res. 2022 04; 310:114473. . View in PubMed
• Using the Alzheimer’s Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer’s disease Alzheimers Dement. 2022 04; 18(4):824-857. . View in PubMed
• Characterizing plasma NfL in a community-dwelling multi-ethnic cohort: Results from the HABLE study Alzheimers Dement. 2022 02; 18(2):240-250. . View in PubMed
• A blood screening tool for detecting mild cognitive impairment and Alzheimer’s disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research Alzheimers Dement. 2022 01; 18(1):77-87. . View in PubMed
• Mapping Complex Brain Torque Components and Their Genetic Architecture and Phenomic Associations in 24,112 Individuals Biol Psychiatry. 2022 04 15; 91(8):753-768. . View in PubMed
• Proteomic Profiles of Neurodegeneration Among Mexican Americans and Non-Hispanic Whites in the HABS-HD Study J Alzheimers Dis. 2022; 86(3):1243-1254. . View in PubMed
• Neurodegeneration from the AT(N) framework is different among Mexican Americans compared to non-Hispanic Whites: A Health & Aging Brain among Latino Elders (HABLE) Study Alzheimers Dement (Amst). 2022; 14(1):e12267. . View in PubMed
• Vascular risk profile and white matter hyperintensity volume among Mexican Americans and non-Hispanic Whites: The HABLE study Alzheimers Dement (Amst). 2022; 14(1):e12263. . View in PubMed
• Autosomal dominant and sporadic late onset Alzheimer’s disease share a common in vivo pathophysiology Brain. 2022 10 21; 145(10):3594-3607. . View in PubMed
• Reinforcement learning with associative or discriminative generalization across states and actions: fMRI at 3 T and 7 T Hum Brain Mapp. 2022 10 15; 43(15):4750-4790. . View in PubMed
• The Link between APOE4 Presence and Neuropsychological Test Performance among Mexican Americans and Non-Hispanic Whites of the Multiethnic Health & Aging Brain Study – Health Disparities Cohort Dement Geriatr Cogn Disord. 2022; 51(1):26-31. . View in PubMed
• Characterization of Mild Cognitive Impairment and Dementia among Community-Dwelling Mexican Americans and Non-Hispanic Whites J Alzheimers Dis. 2022; 90(2):905-915. . View in PubMed
• Anatomical and topographical variations in the distribution of brain metastases based on primary cancer origin and molecular subtypes: a systematic review Neurooncol Adv. 2022 Jan-Dec; 4(1):vdab170. . View in PubMed
• Frontoinsular cortical microstructure is linked to life satisfaction in young adulthood Brain Imaging Behav. 2021 Dec; 15(6):2775-2789. . View in PubMed
• Distribution and volume analysis of early hemorrhagic contusions by MRI after traumatic brain injury: a preliminary report of the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) Brain Imaging Behav. 2021 Dec; 15(6):2804-2812. . View in PubMed
• Perivascular Space Imaging at Ultrahigh Field MR Imaging Magn Reson Imaging Clin N Am. 2021 Feb; 29(1):67-75. . View in PubMed
• The Longitudinal Early-onset Alzheimer’s Disease Study (LEADS): Framework and methodology Alzheimers Dement. 2021 12; 17(12):2043-2055. . View in PubMed
• Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset? Neuroimage. 2021 11; 243:118502.. View in PubMed
• Three-dimensional self-attention conditional GAN with spectral normalization for multimodal neuroimaging synthesis Magn Reson Med. 2021 09; 86(3):1718-1733. . View in PubMed
• Improving brain age estimates with deep learning leads to identification of novel genetic factors associated with brain aging Neurobiol Aging. 2021 09; 105:199-204. . View in PubMed
• RNA sequencing of whole blood reveals early alterations in immune cells and gene expression in Parkinson’s disease Nat Aging. 2021 08; 1(8):734-747. . View in PubMed
• Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson’s Disease Mov Disord. 2021 08; 36(8):1972-1978. . View in PubMed
• Transcranial eddy current damping sensors for detection and imaging of hemorrhagic stroke: feasibility in benchtop experimentation Neurosurg Focus. 2021 07; 51(1):E15. . View in PubMed
• A systematic review of next-generation point-of-care stroke diagnostic technologies Neurosurg Focus. 2021 07; 51(1):E11. . View in PubMed
• Body mass index, time of day and genetics affect perivascular spaces in the white matter J Cereb Blood Flow Metab. 2021 07; 41(7):1563-1578. . View in PubMed
• Early neuroinflammation is associated with lower amyloid and tau levels in cognitively normal older adults Brain Behav Immun. 2021 05; 94:299-307. . View in PubMed
• Global and Regional Changes in Perivascular Space in Idiopathic and Familial Parkinson’s Disease Mov Disord. 2021 05; 36(5):1126-1136. . View in PubMed
• Gray Matter Atrophy: The Impacts of Resective Surgery and Vagus Nerve Stimulation in Drug-Resistant Epilepsy World Neurosurg. 2021 05; 149:e535-e545. . View in PubMed
• Tractography Processing with the Sparse Closest Point Transform Neuroinformatics. 2021 04; 19(2):367-378. . View in PubMed
• Neuroimaging PheWAS (Phenome-Wide Association Study): A Free Cloud-Computing Platform for Big-Data, Brain-Wide Imaging Association Studies Neuroinformatics. 2021 04; 19(2):285-303. . View in PubMed
• Volumetric distribution of perivascular space in relation to mild cognitive impairment Neurobiol Aging. 2021 03; 99:28-43. . View in PubMed
• The effect of body mass index on hippocampal morphology and memory performance in late childhood and adolescence Hippocampus. 2021 02; 31(2):189-200. . View in PubMed
• Brain volumetric deficits in MAPT mutation carriers: a multisite study Ann Clin Transl Neurol. 2021 01; 8(1):95-110. . View in PubMed
• The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression J Alzheimers Dis. 2021; 80(3):991-1002. . View in PubMed
• Functional Outcomes Over the First Year After Moderate to Severe Traumatic Brain Injury in the Prospective, Longitudinal TRACK-TBI Study JAMA Neurol. 2021 08 01; 78(8):982-992. . View in PubMed
• Association of Sex and Age With Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study JAMA Netw Open. 2021 04 01; 4(4):e213046. . View in PubMed
• The Health & Aging Brain among Latino Elders (HABLE) study methods and participant characteristics Alzheimers Dement (Amst). 2021; 13(1):e12202. . View in PubMed
• Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI JAMA Neurol. 2021 09 01; 78(9):1137-1148. . View in PubMed
• Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration Neurology. 2021 05 04; 96(18):e2296-e2312. . View in PubMed
• Morphological Development Trajectory and Structural Covariance Network of the Human Fetal Cortical Plate during the Early Second Trimester Cereb Cortex. 2021 08 26; 31(10):4794-4807. . View in PubMed
• Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury: Findings From the TRACK-TBI Study JAMA Netw Open. 2021 03 01; 4(3):e213467. . View in PubMed
• Retrospective motion artifact correction of structural MRI images using deep learning improves the quality of cortical surface reconstructions Neuroimage. 2021 04 15; 230:117756. . View in PubMed
• Editorial: How Will Aducanumab Approval Impact AD Research? J Prev Alzheimers Dis. 2021; 8(4):391-392.. View in PubMed
• Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer’s Disease Neuroimaging Initiative Depression Project Biol Psychiatry. 2021 04 15; 89(8):757-765. . View in PubMed
• Laminar perfusion imaging with zoomed arterial spin labeling at 7 Tesla Neuroimage. 2021 12 15; 245:118724. . View in PubMed
• Using Fractional Anisotropy Imaging to Detect Mild Cognitive Impairment and Alzheimer’s Disease among Mexican Americans and Non-Hispanic Whites: A HABLE Study Dement Geriatr Cogn Disord. 2021; 50(3):266-273. . View in PubMed
• Selective morphological and volumetric alterations in the hippocampus of children exposed in utero to gestational diabetes mellitus Hum Brain Mapp. 2021 06 01; 42(8):2583-2592. . View in PubMed
• MRI biomarkers of small vessel disease and cognition: A cross-sectional study of a cognitively normal Mexican American cohort Alzheimers Dement (Amst). 2021; 13(1):e12236. . View in PubMed
• Robust Cortical Thickness Morphometry of Neonatal Brain and Systematic Evaluation Using Multi-Site MRI Datasets Front Neurosci. 2021; 15:650082. . View in PubMed
• Ultra-high field magnetic resonance imaging for localization of corticotropin-secreting pituitary adenomas Neuroradiology. 2020 Aug; 62(8):1051-1054. . View in PubMed
• Methodological considerations in designing and implementing the harmonized diagnostic assessment of dementia for longitudinal aging study in India (LASI-DAD) Biodemography Soc Biol. 2020 Jul-Sep; 65(3):189-213. . View in PubMed
• The Dementias Platform UK (DPUK) Data Portal Eur J Epidemiol. 2020 Jun; 35(6):601-611. . View in PubMed
• The connections of the insular VEN area in great apes: A histologically-guided ex vivo diffusion tractography study Prog Neurobiol. 2020 12; 195:101941. . View in PubMed
• Early brain biomarkers of post-traumatic seizures: initial report of the multicentre epilepsy bioinformatics study for antiepileptogenic therapy (EpiBioS4Rx) prospective study J Neurol Neurosurg Psychiatry. 2020 11; 91(11):1154-1157. . View in PubMed
• Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression Mov Disord. 2020 11; 35(11):1999-2008. . View in PubMed
• Evolution of Alzheimer’s Disease Cerebrospinal Fluid Biomarkers in Early Parkinson’s Disease Ann Neurol. 2020 09; 88(3):574-587. . View in PubMed
• Quality of life and caregiver burden in familial frontotemporal lobar degeneration: Analyses of symptomatic and asymptomatic individuals within the LEFFTDS cohort Alzheimers Dement. 2020 08; 16(8):1115-1124. . View in PubMed
• A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid Alzheimers Dement. 2020 06; 16(6):821-830. . View in PubMed
• Interaction effect of alcohol consumption and Alzheimer disease polygenic risk score on the brain cortical thickness of cognitively normal subjects Alcohol. 2020 06; 85:1-12. . View in PubMed
• APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline Nature. 2020 05; 581(7806):71-76. . View in PubMed
• Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson’s Disease Participants in the Parkinson’s Progression Markers Initiative: A Cross-Sectional Study Mov Disord. 2020 05; 35(5):833-844. . View in PubMed
• Functional connectivity among brain regions affected in Alzheimer’s disease is associated with CSF TNF-a in APOE4 carriers Neurobiol Aging. 2020 02; 86:112-122. . View in PubMed
• The longitudinal evaluation of familial frontotemporal dementia subjects protocol: Framework and methodology Alzheimers Dement. 2020 01; 16(1):22-36. . View in PubMed
• Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint Alzheimers Dement. 2020 01; 16(1):11-21. . View in PubMed
• Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases Alzheimers Dement. 2020 01; 16(1):118-130. . View in PubMed
• Imputation Strategy for Reliable Regional MRI Morphological Measurements Neuroinformatics. 2020 01; 18(1):59-70. . View in PubMed
• Tractography reproducibility challenge with empirical data (TraCED): The 2017 ISMRM diffusion study group challenge J Magn Reson Imaging. 2020 01; 51(1):234-249. . View in PubMed
• Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium Alzheimers Dement. 2020 01; 16(1):106-117. . View in PubMed
• Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration Alzheimers Dement. 2020 01; 16(1):49-59. . View in PubMed
• Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort Alzheimers Dement. 2020 01; 16(1):60-70. . View in PubMed
• Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson’s Progression Markers Initiative (PPMI): a cross-sectional study Lancet Neurol. 2020 01; 19(1):71-80. . View in PubMed
• Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration Alzheimers Dement. 2020 01; 16(1):37-48. . View in PubMed
• Identification of Dysregulated Genes for Late-Onset Alzheimer’s Disease Using Gene Expression Data in Brain J Alzheimers Dis Parkinsonism. 2020; 10(6). . View in PubMed
• Associations between Vascular Function and Tau PET Are Associated with Global Cognition and Amyloid J Neurosci. 2020 10 28; 40(44):8573-8586. . View in PubMed
• Multiplex Networks to Characterize Seizure Development in Traumatic Brain Injury Patients Front Neurosci. 2020; 14:591662. . View in PubMed
• Morphometric development of the human fetal cerebellum during the early second trimester Neuroimage. 2020 02 15; 207:116372. . View in PubMed
• Disruption and Compensation of Sulcation-based Covariance Networks in Neonatal Brain Growth after Perinatal Injury Cereb Cortex. 2020 11 03; 30(12):6238-6253. . View in PubMed
• THC Exposure is Reflected in the Microstructure of the Cerebral Cortex and Amygdala of Young Adults Cereb Cortex. 2020 07 30; 30(9):4949-4963. . View in PubMed
• Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants Sci Rep. 2020 01 30; 10(1):10. . View in PubMed
• Magnitude and timing of major white matter tract maturation from infancy through adolescence with NODDI Neuroimage. 2020 05 15; 212:116672. . View in PubMed
• Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson’s disease Sci Data. 2020 02 24; 7(1):67. . View in PubMed
• The genetic architecture of the human cerebral cortex Science. 2020 03 20; 367(6484). . View in PubMed
• Parity is associated with cognitive function and brain age in both females and males Sci Rep. 2020 04 08; 10(1):6100. . View in PubMed
• Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types Cell Rep. 2020 08 18; 32(7):108029. . View in PubMed
• Compressive Big Data Analytics: An ensemble meta-algorithm for high-dimensional multisource datasets PLoS One. 2020; 15(8):e0228520. . View in PubMed
• Nonlinear Z-score modeling for improved detection of cognitive abnormality Alzheimers Dement (Amst). 2019 Dec; 11:797-808. . View in PubMed
• Nonparenchymal fluid is the source of increased mean diffusivity in preclinical Alzheimer’s disease Alzheimers Dement (Amst). 2019 Dec; 11:348-354. . View in PubMed
• Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study JAMA Neurol. 2019 Sep 01; 76(9):1049-1059. . View in PubMed
• A MACHINE LEARNING MODEL TO PREDICT SEIZURE SUSCEPTIBILITY FROM RESTING-STATE FMRI CONNECTIVITY Spring Simul Conf. 2019 Apr-May; 2019. . View in PubMed
• Br J Radiol. 2019 Feb; 92(1094):20180492. . View in PubMed
• Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment Alzheimers Dement. 2019 12; 15(12):1568-1575. . View in PubMed
• Imaging biomarkers of posttraumatic epileptogenesis Epilepsia. 2019 11; 60(11):2151-2162. . View in PubMed
• Genetic architecture of subcortical brain structures in 38,851 individuals Nat Genet. 2019 11; 51(11):1624-1636. . View in PubMed
• Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers Neurobiol Aging. 2019 11; 83:54-62. . View in PubMed
• TADPOLE Challenge: Accurate Alzheimer’s disease prediction through crowdsourced forecasting of future data Predict Intell Med. 2019 10; 11843:1-10. . View in PubMed
• Longitudinal analyses of cerebrospinal fluid a-Synuclein in prodromal and early Parkinson’s disease Mov Disord. 2019 09; 34(9):1354-1364. . View in PubMed
• Signal Hyperintensity on Unenhanced T1-Weighted Brain and Cervical Spinal Cord MR Images after Multiple Doses of Linear Gadolinium-Based Contrast Agent AJNR Am J Neuroradiol. 2019 08; 40(8):1274-1281. . View in PubMed
• 7-Tesla MRI of the brain in a research subject with bilateral, total knee replacement implants: Case report and proposed safety guidelines Magn Reson Imaging. 2019 04; 57:313-316. . View in PubMed
• Big data sharing and analysis to advance research in post-traumatic epilepsy Neurobiol Dis. 2019 03; 123:127-136. . View in PubMed
• The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol Neurobiol Dis. 2019 03; 123:110-114. . View in PubMed
• Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction Nat Med. 2019 02; 25(2):270-276. . View in PubMed
• Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis Epilepsy Res. 2019 02; 150:46-57. . View in PubMed
• Using Virtual Reality to Improve Performance and User Experience in Manual Correction of MRI Segmentation Errors by Non-experts J Digit Imaging. 2019 02; 32(1):97-104. . View in PubMed
• Vascular dysfunction-The disregarded partner of Alzheimer’s disease Alzheimers Dement. 2019 01; 15(1):158-167. . View in PubMed
• Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke Ann Neurol. 2019 01; 85(1):125-136. . View in PubMed
• Understanding disease progression and improving Alzheimer’s disease clinical trials: Recent highlights from the Alzheimer’s Disease Neuroimaging Initiative Alzheimers Dement. 2019 01; 15(1):106-152. . View in PubMed
• Predictive Big Data Analytics using the UK Biobank Data Sci Rep. 2019 04 12; 9(1):6012. . View in PubMed
• Age-Related Differences in Brain Morphology and the Modifiers in Middle-Aged and Older Adults Cereb Cortex. 2019 09 13; 29(10):4169-4193. . View in PubMed
• Hippocampal Shape Maturation in Childhood and Adolescence Cereb Cortex. 2019 08 14; 29(9):3651-3665. . View in PubMed
• Limits to anatomical accuracy of diffusion tractography using modern approaches Neuroimage. 2019 01 15; 185:1-11. . View in PubMed
• Characterization of lenticulostriate arteries with high resolution black-blood T1-weighted turbo spin echo with variable flip angles at 3 and 7? Tesla. Neuroimage. 2019 10 01; 199:184-193.. View in PubMed
• The LONI QC System: A Semi-Automated, Web-Based and Freely-Available Environment for the Comprehensive Quality Control of Neuroimaging Data Front Neuroinform. 2019; 13:60. . View in PubMed
• Risk of Posttraumatic Stress Disorder and Major Depression in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study JAMA Psychiatry. 2019 03 01; 76(3):249-258. . View in PubMed
• Perivascular space fluid contributes to diffusion tensor imaging changes in white matter Neuroimage. 2019 08 15; 197:243-254. . View in PubMed
• Image processing approaches to enhance perivascular space visibility and quantification using MRI Sci Rep. 2019 08 26; 9(1):12351. . View in PubMed
• Grant Report on PREDICT-ADFTD: Multimodal Imaging Prediction of AD/FTD and Differential Diagnosis J Psychiatr Brain Sci. 2019; 4. . View in PubMed
• The Parkinson’s progression markers initiative (PPMI) – establishing a PD biomarker cohort Ann Clin Transl Neurol. 2018 Dec; 5(12):1460-1477. . View in PubMed
• When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity Brain Struct Funct. 2018 Jul; 223(6):2841-2858. . View in PubMed
• Value of pituitary gland MRI at 7 T in Cushing’s disease and relationship to inferior petrosal sinus sampling: case report J Neurosurg. 2018 Mar 01; 1-5. . View in PubMed
• Modeling topographic regularity in structural brain connectivity with application to tractogram filtering Neuroimage. 2018 12; 183:87-98. . View in PubMed
• The role of brain vasculature in neurodegenerative disorders Nat Neurosci. 2018 10; 21(10):1318-1331. . View in PubMed
• Response to Zywieck and Kirkby paper Neurobiol Aging. 2018 09; 69:298-299. . View in PubMed
• Classifying Alzheimer’s disease with brain imaging and genetic data using a neural network framework Neurobiol Aging. 2018 08; 68:151-158. . View in PubMed
• Longitudinal Change of Clinical and Biological Measures in Early Parkinson’s Disease: Parkinson’s Progression Markers Initiative Cohort Mov Disord. 2018 05; 33(5):771-782. . View in PubMed
• Brain structure differences between Chinese and Caucasian cohorts: A comprehensive morphometry study Hum Brain Mapp. 2018 05; 39(5):2147-2155. . View in PubMed
• Topological false discovery rates for brain mapping based on signal height Neuroimage. 2018 02 15; 167:478-487. . View in PubMed
• A probabilistic atlas of human brainstem pathways based on connectome imaging data Neuroimage. 2018 04 01; 169:227-239. . View in PubMed
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• Thompson, Paul
• Peterson, Bradley
• Leahy, Richard
• Nayak, Krishna
• Jahanshad, Neda
• Wang, Danny
• Aisen, Paul