Faculty

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David T Woodley, MD
Professor of Dermatology
Dermatology
USC/Norris Cancer Center -Topping #3405 Health Sciences Campus Los Angeles
+1 323 865 0983

Overview

Dr. Woodley was trained in Dermatology in Chapel Hill at the University of North Carolina. He was a Research Fellow at the University of Paris/Rothschild Institute for two years and an Expert Investigator at the National Institutes of Health. He later joined the dermatology faculty at the University of North Carolina where he started the Phototherapy Unit for the treatment of psoriasis.

In 1988, he became professor and vice chair of the Department of Dermatology at Stanford University and ran the Stanford Psoriasis Center and the Immunodermatology Lab. In 1992, he was appointed the Walter J. Hamlin Professor and Chair of the Department of Dermatology at Northwestern University.

In 1999, he joined USC as professor and co-chief of the Division of Dermatology. In 2005, dermatology became an independent academic department, and Dr. Woodley was appointed professor and chair of the new department. He has published over 165 scientific papers and has had continuous NIH funding since 1982.

Publications

PRAS40 Connects Microenvironmental Stress Signaling to Exosome-Mediated Secretion. Mol Cell Biol. 2017 Oct 01; 37(19). View in: PubMed

Extracellular and Non-Chaperone Function of Heat Shock Protein-90alpha (Hsp90a) is Required for Skin Wound Healing. J Invest Dermatol. 2017 Sep 20. View in: PubMed

Gentamicin induces functional type VII collagen in recessive dystrophic epidermolysis bullosa patients. J Clin Invest. 2017 Aug 01; 127(8):3028-3038. View in: PubMed

Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression. Oncogene. 2017 Apr; 36(15):2160-2171. View in: PubMed

Distinct Fibroblasts in the Papillary and Reticular Dermis: Implications for Wound Healing. Dermatol Clin. 2017 Jan; 35(1):95-100. View in: PubMed

Keratinocyte-Secreted Heat Shock Protein-90alpha: Leading Wound Reepithelialization and Closure. Adv Wound Care (New Rochelle). 2016 Apr 01; 5(4):176-184. View in: PubMed

Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90a) to Survive a Hostile Hypoxic Environment. Sci Rep. 2016 Feb 05; 6:20605. View in: PubMed

Dual therapeutic functions of F-5 fragment in burn wounds: preventing wound progression and promoting wound healing in pigs. Mol Ther Methods Clin Dev. 2016; 3:16041. View in: PubMed

Intravenously Administered Recombinant Human Type VII Collagen Derived from Chinese Hamster Ovary Cells Reverses the Disease Phenotype in Recessive Dystrophic Epidermolysis Bullosa Mice. J Invest Dermatol. 2015 Dec; 135(12):3060-3067. View in: PubMed

Reduced Toxicity Conditioning and Allogeneic Hematopoietic Progenitor Cell Transplantation for Recessive Dystrophic Epidermolysis Bullosa. J Pediatr. 2015 Sep; 167(3):765-9. e1. View in: PubMed

Recessive Dystrophic Epidermolysis Bullosa: Advances in the Laboratory Leading to New Therapies. J Invest Dermatol. 2015 Jul; 135(7):1705-1707. View in: PubMed

Hsp90a and Hsp90ß together operate a hypoxia and nutrient paucity stress-response mechanism during wound healing. J Cell Sci. 2015 Apr 15; 128(8):1475-80. View in: PubMed

Keratinocyte Migration and a Hypothetical New Role for Extracellular Heat Shock Protein 90 Alpha in Orchestrating Skin Wound Healing. Adv Wound Care (New Rochelle). 2015 Apr 01; 4(4):203-212. View in: PubMed

Treatment of fibroelastolytic papulosis with fractionated carbon dioxide laser. J Cosmet Laser Ther. 2015 Apr; 17(2):90-2. View in: PubMed

Definitions and outcome measures for mucous membrane pemphigoid: recommendations of an international panel of experts. J Am Acad Dermatol. 2015 Jan; 72(1):168-74. View in: PubMed

Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa. Mol Ther. 2014 Oct; 22(10):1741-52. View in: PubMed

Omalizumab therapy for bullous pemphigoid. J Am Acad Dermatol. 2014 Sep; 71(3):468-74. View in: PubMed

From epidemiology and genetics to diagnostics, outcome measures, and novel treatments in autoimmune bullous diseases. J Invest Dermatol. 2014 Sep; 134(9):2298-2300. View in: PubMed

Inherited epidermolysis bullosa: updated recommendations on diagnosis and classification. J Am Acad Dermatol. 2014 Jun; 70(6):1103-26. View in: PubMed

De novo anti-type VII collagen antibodies in patients with recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2014 Apr; 134(4):1138-1140. View in: PubMed

Identification of the critical therapeutic entity in secreted Hsp90a that promotes wound healing in newly re-standardized healthy and diabetic pig models. PLoS One. 2014; 9(12):e113956. View in: PubMed

Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Mol Cell Biol. 2013 Dec; 33(24):4947-59. View in: PubMed

Intravenously injected recombinant human type VII collagen homes to skin wounds and restores skin integrity of dystrophic epidermolysis bullosa. J Invest Dermatol. 2013 Jul; 133(7):1910-3. View in: PubMed

Topical application of recombinant type VII collagen incorporates into the dermal-epidermal junction and promotes wound closure. Mol Ther. 2013 Jul; 21(7):1335-44. View in: PubMed

Assessing hairdressers' knowledge of scalp and neck melanoma and their willingness to detect lesions and make referrals to dermatologists. J Am Acad Dermatol. 2013 Jan; 68(1):183-5. View in: PubMed

Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionally. Int Rev Cell Mol Biol. 2013; 303:203-35. View in: PubMed

The anti-motility signaling mechanism of TGFß3 that controls cell traffic during skin wound healing. Biol Open. 2012 Dec 15; 1(12):1169-77. View in: PubMed

Successful treatment of bullous pemphigoid with omalizumab. Arch Dermatol. 2012 Nov; 148(11):1241-3. View in: PubMed

Utilizing hairdressers for early detection of head and neck melanoma: an untapped resource. J Am Acad Dermatol. 2012 Apr; 66(4):687-8. View in: PubMed

Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts. J Am Acad Dermatol. 2012 Mar; 66(3):479-85. View in: PubMed

Epidermolysis bullosa acquisita: autoimmunity to anchoring fibril collagen. Autoimmunity. 2012 Feb; 45(1):91-101. View in: PubMed

A potentially common peptide target in secreted heat shock protein-90a for hypoxia-inducible factor-1a-positive tumors. Mol Biol Cell. 2012 Feb; 23(4):602-13. View in: PubMed

Epidermolysis bullosa acquisita. Clin Dermatol. 2012 Jan-Feb; 30(1):60-9. View in: PubMed

A fragment of secreted Hsp90a carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice. J Clin Invest. 2011 Nov; 121(11):4348-61. View in: PubMed

Congenital epidermolysis bullosa acquisita: vertical transfer of maternal autoantibody from mother to infant. Arch Dermatol. 2011 Mar; 147(3):337-41. View in: PubMed

TbetaRI/Alk5-independent TbetaRII signaling to ERK1/2 in human skin cells according to distinct levels of TbetaRII expression. J Cell Sci. 2011 Jan 01; 124(Pt 1):19-24. View in: PubMed

Skin blood flow in patients with stage 5 chronic kidney disease on hemodialysis. J Ren Nutr. 2010 Sep; 20(5 Suppl):S89-94. View in: PubMed

Bone marrow transplantation for recessive dystrophic epidermolysis bullosa. N Engl J Med. 2010 Aug 12; 363(7):629-39. View in: PubMed

Reliability and convergent validity of two outcome instruments for pemphigus. J Invest Dermatol. 2009 Oct; 129(10):2404-10. View in: PubMed

Non-compensating roles between Nckalpha and Nckbeta in PDGF-BB signaling to promote human dermal fibroblast migration. J Invest Dermatol. 2009 Aug; 129(8):1909-20. View in: PubMed

Potential new insight into the pathogenesis of psoriasis. Arch Dermatol. 2009 Jun; 145(6):713-4. View in: PubMed

Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration. J Cell Sci. 2009 May 15; 122(Pt 10):1495-8. View in: PubMed

TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites. Cell. 2009 Mar 06; 136(5):891-902. View in: PubMed

Injection of recombinant human type VII collagen corrects the disease phenotype in a murine model of dystrophic epidermolysis bullosa. Mol Ther. 2009 Jan; 17(1):26-33. View in: PubMed

Familial epidermolysis bullosa acquisita. Dermatol Online J. 2008 Dec 15; 14(12):2. View in: PubMed

Duplicating autoimmune bullous diseases by passively transferring autoantibodies into animals. J Invest Dermatol. 2008 Oct 06; 128(E3):E25-7. View in: PubMed

Duplicating Autoimmune Bullous Diseases by Passively Transferring Autoantibodies into Animals. J Invest Dermatol. 2008 Oct; 128 Suppl 3:E25-7. View in: PubMed

The role of oxygen in wound healing: a review of the literature. Dermatol Surg. 2008 Sep; 34(9):1159-69. View in: PubMed

Profiling motility signal-specific genes in primary human keratinocytes. J Invest Dermatol. 2008 Aug; 128(8):1981-90. View in: PubMed

Characterization of molecular mechanisms underlying mutations in dystrophic epidermolysis bullosa using site-directed mutagenesis. J Biol Chem. 2008 Jun 27; 283(26):17838-45. View in: PubMed

The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB. J Am Acad Dermatol. 2008 Jun; 58(6):931-50. View in: PubMed

Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healing. Mol Cell Biol. 2008 May; 28(10):3344-58. View in: PubMed

Hypoxia induces epidermal keratinocyte matrix metalloproteinase-9 secretion via the protein kinase C pathway. J Cell Physiol. 2008 Jan; 214(1):47-55. View in: PubMed

Autoimmunity to type VII collagen: epidermolysis bullosa acquisita. Curr Dir Autoimmun. 2008; 10:195-205. View in: PubMed

Autoimmunity to type VII collagen: epidermolysis bullosa acquisita. Clin Rev Allergy Immunol. 2007 Oct; 33(1-2):78-84. View in: PubMed

Nckbeta adapter controls neuritogenesis by maintaining the cellular paxillin level. Mol Cell Biol. 2007 Sep; 27(17):6001-11. View in: PubMed

The cartilage matrix protein subdomain of type VII collagen is pathogenic for epidermolysis bullosa acquisita. Am J Pathol. 2007 Jun; 170(6):2009-18. View in: PubMed

Extracellular heat shock protein-90alpha: linking hypoxia to skin cell motility and wound healing. EMBO J. 2007 Mar 07; 26(5):1221-33. View in: PubMed

Intravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing. Mol Ther. 2007 Mar; 15(3):628-35. View in: PubMed

The role of IgE anti-basement membrane zone autoantibodies in bullous pemphigoid. Arch Dermatol. 2007 Feb; 143(2):249-50. View in: PubMed

Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J Invest Dermatol. 2006 Sep; 126(9):2096-105. View in: PubMed

PKCdelta clustering at the leading edge and mediating growth factor-enhanced, but not ecm-initiated, dermal fibroblast migration. J Invest Dermatol. 2006 Jun; 126(6):1233-43. View in: PubMed

Induction of epidermolysis bullosa acquisita in mice by passive transfer of autoantibodies from patients. J Invest Dermatol. 2006 Jun; 126(6):1323-30. View in: PubMed

Fibroblasts as target cells for DEB gene therapy. J Invest Dermatol. 2006 Apr; 126(4):708-10. View in: PubMed

A "traffic control" role for TGFbeta3: orchestrating dermal and epidermal cell motility during wound healing. J Cell Biol. 2006 Mar 27; 172(7):1093-105. View in: PubMed

Pterygium inversum unguis associated with stroke. J Am Acad Dermatol. 2005 Sep; 53(3):501-3. View in: PubMed

Evidence that anti-type VII collagen antibodies are pathogenic and responsible for the clinical, histological, and immunological features of epidermolysis bullosa acquisita. J Invest Dermatol. 2005 May; 124(5):958-64. View in: PubMed

Wound-healing perspectives. Dermatol Clin. 2005 Apr; 23(2):181-92. View in: PubMed

Widespread unilateral plaques in a 68-year-old woman after neurosurgery. Arch Dermatol. 2004 Dec; 140(12):1531-6. View in: PubMed

Signals that initiate, augment, and provide directionality for human keratinocyte motility. J Invest Dermatol. 2004 Oct; 123(4):622-33. View in: PubMed

Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo. Mol Ther. 2004 Aug; 10(2):318-26. View in: PubMed

A patient with both bullous pemphigoid and epidermolysis bullosa acquisita: an example of intermolecular epitope spreading. J Am Acad Dermatol. 2004 Jul; 51(1):118-22. View in: PubMed

Epidermolysis bullosa: then and now. J Am Acad Dermatol. 2004 Jul; 51(1 Suppl):S55-7. View in: PubMed

Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa. Nat Med. 2004 Jul; 10(7):693-5. View in: PubMed

Mechanisms of human skin cell motility. Histol Histopathol. 2004 10; 19(4):1311-24. View in: PubMed

Mechanism of human dermal fibroblast migration driven by type I collagen and platelet-derived growth factor-BB. Mol Biol Cell. 2004 Jan; 15(1):294-309. View in: PubMed

Normal and gene-corrected dystrophic epidermolysis bullosa fibroblasts alone can produce type VII collagen at the basement membrane zone. J Invest Dermatol. 2003 Nov; 121(5):1021-8. View in: PubMed

Epidermolysis bullosa acquisita in childhood. J Dermatol. 2003 Mar; 30(3):226-9. View in: PubMed

Migration of human keratinocytes in plasma and serum and wound re-epithelialisation. Lancet. 2003 Feb 15; 361(9357):574-6. View in: PubMed

Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa. Nat Genet. 2002 Dec; 32(4):670-5. View in: PubMed

The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with crohn's disease have autoantibodies to type VII collagen. J Invest Dermatol. 2002 Jun; 118(6):1059-64. View in: PubMed

Drug-induced epidermolysis bullosa acquisita with antibodies to type VII collagen. J Am Acad Dermatol. 2002 May; 46(5 Suppl):S161-4. View in: PubMed

The first international consensus on mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment, and prognostic indicators. Arch Dermatol. 2002 Mar; 138(3):370-9. View in: PubMed

An important role for protein kinase C-delta in human keratinocyte migration on dermal collagen. Exp Cell Res. 2002 Feb 15; 273(2):219-28. View in: PubMed

The recombinant expression of full-length type VII collagen and characterization of molecular mechanisms underlying dystrophic epidermolysis bullosa. J Biol Chem. 2002 Jan 18; 277(3):2118-24. View in: PubMed

Epidermolysis bullosa acquisita: update and review. Clin Dermatol. 2001 Nov-Dec; 19(6):712-8. View in: PubMed

Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton. Oncogene. 2001 Oct 1; 20(44):6403-17. View in: PubMed

Phosphorylation of focal adhesion kinase (pp125(FAK)) is increased in human keratinocytes induced to migrate by extracellular matrices. J Cell Physiol. 2001 Jul; 188(1):24-32. View in: PubMed

The carboxyl terminus of type VII collagen mediates antiparallel dimer formation and constitutes a new antigenic epitope for epidermolysis Bullosa acquisita autoantibodies. J Biol Chem. 2001 Jun 15; 276(24):21649-55. View in: PubMed

Autoantibodies to type VII collagen have heterogeneous subclass and light chain compositions and their complement-activating capacities do not correlate with the inflammatory clinical phenotype. J Clin Immunol. 2000 Nov; 20(6):416-23. View in: PubMed

Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb. Mol Cell Biol. 2000 Nov; 20(21):7867-80. View in: PubMed

Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression. Mol Biol Cell. 2000 Nov; 11(11):3835-48. View in: PubMed

Prokaryotic expression, purification, and reconstitution of biological activities (Antiprotease, antitumor, and heparin-binding) for tissue factor pathway inhibitor-2. Biochem Biophys Res Commun. 2000 Oct 5; 276(3):1286-94. View in: PubMed

Development and characterization of a recombinant truncated type VII collagen "minigene". Implication for gene therapy of dystrophic epidermolysis bullosa. J Biol Chem. 2000 Aug 11; 275(32):24429-35. View in: PubMed

Induction of keratinocyte IL-8 expression and secretion by IgG autoantibodies as a novel mechanism of epidermal neutrophil recruitment in a pemphigus variant. Clin Exp Immunol. 2000 Jan; 119(1):217-24. View in: PubMed

Thalidomide increases human keratinocyte migration and proliferation. J Invest Dermatol. 1999 Nov; 113(5):720-4. View in: PubMed

Alpha 2 beta 1 integrin mediates dermal fibroblast attachment to type VII collagen via a 158-amino-acid segment of the NC1 domain. Exp Cell Res. 1999 Jun 15; 249(2):231-9. View in: PubMed

Bullous systemic lupus erythematosus with autoantibodies recognizing multiple skin basement membrane components, bullous pemphigoid antigen 1, laminin-5, laminin-6, and type VII collagen. Arch Dermatol. 1999 May; 135(5):569-73. View in: PubMed

NC1 domain of type VII collagen binds to the beta3 chain of laminin 5 via a unique subdomain within the fibronectin-like repeats. J Invest Dermatol. 1999 Feb; 112(2):177-83. View in: PubMed

Molecular cloning and characterization of a cDNA encoding canine type VII collagen non-collagenous (NC1) domain, the target antigen of autoimmune disease epidermolysis bullosa acquisita (EBA). Biochim Biophys Acta. 1998 Oct 22; 1408(1):25-34. View in: PubMed

HT-1080 fibrosarcoma cell matrix degradation and invasion are inhibited by the matrix-associated serine protease inhibitor TFPI-2/33 kDa MSPI. Int J Cancer. 1998 May 29; 76(5):749-56. View in: PubMed

Integrin alpha 5 beta 1 expression is required for inhibition of keratinocyte migration by ganglioside GT1b. Exp Cell Res. 1998 Mar 15; 239(2):311-9. View in: PubMed

Epitope spreading: lessons from autoimmune skin diseases. J Invest Dermatol. 1998 Feb; 110(2):103-9. View in: PubMed

Hypoxia increases human keratinocyte motility on connective tissue. J Clin Invest. 1997 Dec 1; 100(11):2881-91. View in: PubMed

Laminin-5 inhibits human keratinocyte migration. Exp Cell Res. 1997 Jun 15; 233(2):330-9. View in: PubMed

Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin. J Biol Chem. 1997 Jun 06; 272(23):14516-22. View in: PubMed

Laminin-6 and laminin-5 are recognized by autoantibodies in a subset of cicatricial pemphigoid. J Invest Dermatol. 1997 Jun; 108(6):848-53. View in: PubMed

Nonsecretory IgA1 autoantibodies targeting desmosomal component desmoglein 3 in intraepidermal neutrophilic IgA dermatosis. Am J Pathol. 1997 Jun; 150(6):1901-7. View in: PubMed

Modulation of type VII collagen (anchoring fibril) expression by retinoids in human skin cells. Biochim Biophys Acta. 1997 Apr 10; 1351(3):333-40. View in: PubMed

Treatment of refractory epidermolysis bullosa acquisita with extracorporeal photochemotherapy. Br J Dermatol. 1997 Mar; 136(3):415-20. View in: PubMed

Ultraviolet A irradiation upregulates type VII collagen expression in human dermal fibroblasts. J Invest Dermatol. 1997 Feb; 108(2):125-8. View in: PubMed

Development of an ELISA for rapid detection of anti-type VII collagen autoantibodies in epidermolysis bullosa acquisita. J Invest Dermatol. 1997 Jan; 108(1):68-72. View in: PubMed

Extracellular matrix-associated serine protease inhibitors (Mr 33,000, 31,000, and 27,000) are single-gene products with differential glycosylation: cDNA cloning of the 33-kDa inhibitor reveals its identity to tissue factor pathway inhibitor-2. Arch Biochem Biophys. 1996 Nov 1; 335(1):82-92. View in: PubMed

Restricted expression and function of laminin 1-binding integrins in normal and malignant oral mucosal keratinocytes. Cell Adhes Commun. 1996 Sep; 4(3):159-74. View in: PubMed

The 105-kDa basement membrane autoantigen p105 is N-terminally homologous to a tumor-associated antigen. J Invest Dermatol. 1996 Aug; 107(2):209-14. View in: PubMed

Hydrogen peroxide inhibits human keratinocyte migration. Dermatol Surg. 1996 Jun; 22(6):525-9. View in: PubMed

Enhanced modulation of keratinocyte motility by transforming growth factor-alpha (TGF-alpha) relative to epidermal growth factor (EGF). J Invest Dermatol. 1996 Apr; 106(4):590-7. View in: PubMed

Porphyria cutanea tarda preceding AIDS. Lancet. 1996 Jan 20; 347(8995):190. View in: PubMed

Linear IgA bullous dermatosis. Characterization of a subset of patients with concurrent IgA and IgG anti-basement membrane autoantibodies. Arch Dermatol. 1995 Dec; 131(12):1432-7. View in: PubMed

Alpha 1-antitrypsin is degraded and non-functional in chronic wounds but intact and functional in acute wounds: the inhibitor protects fibronectin from degradation by chronic wound fluid enzymes. J Invest Dermatol. 1995 Oct; 105(4):572-8. View in: PubMed

Ganglioside GT1b inhibits keratinocyte adhesion and migration on a fibronectin matrix. J Invest Dermatol. 1995 Aug; 105(2):237-42. View in: PubMed

Canine bullous pemphigoid (BP): identification of the 180-kd canine BP antigen by circulating autoantibodies. Vet Pathol. 1995 Jul; 32(4):387-93. View in: PubMed

A newly identified 105-kD lower lamina lucida autoantigen is an acidic protein distinct from the 105-kD gamma 2 chain of laminin-5. J Invest Dermatol. 1995 Jul; 105(1):75-9. View in: PubMed

Localized linear bullous eruption of systemic lupus erythematosus in a child. Pediatr Dermatol. 1995 Jun; 12(2):138-44. View in: PubMed

Interleukin-1 alpha stimulates keratinocyte migration through an epidermal growth factor/transforming growth factor-alpha-independent pathway. J Invest Dermatol. 1995 May; 104(5):729-33. View in: PubMed

Partial characterization of matrix-associated serine protease inhibitors from human skin cells. J Invest Dermatol. 1995 Mar; 104(3):379-83. View in: PubMed

Novel extracellular matrix-associated serine proteinase inhibitors from human skin fibroblasts. Arch Biochem Biophys. 1995 Feb 20; 317(1):311-4. View in: PubMed

A nonscarring sublamina densa bullous drug eruption. J Am Acad Dermatol. 1995 Feb; 32(2 Pt 2):367-71. View in: PubMed

Type VII collagen specifically binds fibronectin via a unique subdomain within the collagenous triple helix. J Invest Dermatol. 1994 Nov; 103(5):637-41. View in: PubMed

Identification of the epitopes on human type VII collagen for monoclonal antibodies LH 7. 2 and clone I, 185. J Dermatol Sci. 1994 Oct; 8(2):145-50. View in: PubMed

Human keratinocyte migration on type IV collagen. Roles of heparin-binding site and alpha 2 beta 1 integrin. Lab Invest. 1994 Sep; 71(3):401-8. View in: PubMed

A novel 105-kDa lamina lucida autoantigen: association with bullous pemphigoid. J Invest Dermatol. 1994 Jul; 103(1):78-83. View in: PubMed

Hailey-Hailey disease is not allelic to Darier's disease. J Invest Dermatol. 1994 Jun; 102(6):992-3. View in: PubMed

Dibutyryl cyclic AMP modulates keratinocyte migration without alteration of integrin expression. J Invest Dermatol. 1994 Jun; 102(6):891-7. View in: PubMed

Autoimmunity to anchoring fibrils. Adv Dermatol. 1994; 9:61-77; discussion 78. View in: PubMed

Intertrigo: a practical approach. Compr Ther. 1994; 20(7):402-9. View in: PubMed

Epidermal growth factor (EGF) promotes human keratinocyte locomotion on collagen by increasing the alpha 2 integrin subunit. Exp Cell Res. 1993 Dec; 209(2):216-23. View in: PubMed

Re-epithelialization. Human keratinocyte locomotion. Dermatol Clin. 1993 Oct; 11(4):641-6. View in: PubMed

Epitope mapping of type VII collagen. Identification of discrete peptide sequences recognized by sera from patients with acquired epidermolysis bullosa. J Clin Invest. 1993 Oct; 92(4):1831-9. View in: PubMed

Identification and partial characterization of a novel 105-kDalton lower lamina lucida autoantigen associated with a novel immune-mediated subepidermal blistering disease. J Invest Dermatol. 1993 Sep; 101(3):262-7. View in: PubMed

Recessive dystrophic epidermolysis bullosa keratinocytes synthesize type VII collagen alpha chains of normal molecular size but the anchoring fibril assembly is impaired. Biochem Biophys Res Commun. 1993 Jun 15; 193(2):604-10. View in: PubMed

Constitutive synthesis of a 92-kDa keratinocyte-derived type IV collagenase is enhanced by type I collagen and decreased by type IV collagen matrices. J Invest Dermatol. 1992 Dec; 99(6):836-41. View in: PubMed

Differences in direct immunofluorescence staining patterns in epidermolysis bullosa acquisita and bullous pemphigoid. J Am Acad Dermatol. 1992 Nov; 27(5 Pt 1):674-8. View in: PubMed

The large non-collagenous domain (NC-1) of type VII collagen is amino-terminal and chimeric. Homology to cartilage matrix protein, the type III domains of fibronectin and the A domains of von Willebrand factor. Hum Mol Genet. 1992 Oct; 1(7):475-81. View in: PubMed

A double-blind comparison of adhesive bandages with the use of uniform suction blister wounds. Arch Dermatol. 1992 Oct; 128(10):1354-7. View in: PubMed

Congenital localized absence of the skin as a manifestation of epidermolysis bullosa. Arch Dermatol. 1992 Aug; 128(8):1087-90. View in: PubMed

Mechanism of human keratinocyte migration on fibronectin: unique roles of RGD site and integrins. J Cell Physiol. 1992 Jun; 151(3):443-50. View in: PubMed

Integrin receptors and RGD sequences in human keratinocyte migration: unique anti-migratory function of alpha 3 beta 1 epiligrin receptor. J Invest Dermatol. 1992 May; 98(5):764-70. View in: PubMed

Paraneoplastic pemphigus with autoantibody deposition in bronchial epithelium after autologous bone marrow transplantation. JAMA. 1992 Mar 18; 267(11):1500-2. View in: PubMed

Recessive dystrophic epidermolysis bullosa phenotype is preserved in xenografts using SCID mice: development of an experimental in vivo model. J Invest Dermatol. 1992 Feb; 98(2):191-7. View in: PubMed

Human keratinocyte locomotion: the effect of selected cytokines. J Invest Dermatol. 1992 Jan; 98(1):12-6. View in: PubMed

Autoimmunity to type VII collagen. Semin Dermatol. 1991 Sep; 10(3):232-9. View in: PubMed

Human type VII collagen: cDNA cloning and chromosomal mapping of the gene. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):6931-5. View in: PubMed

Salt-split human skin substrate for the immunofluorescent screening of serum from patients with cicatricial pemphigoid and a new method of immunoprecipitation with IgA antibodies. J Am Acad Dermatol. 1991 Jun; 24(6 Pt 1):952-8. View in: PubMed

Vitronectin: effects on keratinocyte motility and inhibition of collagen-induced motility. J Invest Dermatol. 1991 May; 96(5):724-8. View in: PubMed

Epidermolysis bullosa acquisita and associated symptomatic esophageal webs. Arch Dermatol. 1991 Mar; 127(3):373-7. View in: PubMed

Coexistence of pemphigus foliaceus and bullous pemphigoid. Demonstration of autoantibodies that bind to both the pemphigus foliaceus antigen complex and the bullous pemphigoid antigen. Arch Dermatol. 1991 Mar; 127(3):387-90. View in: PubMed

The role of matrix components in human keratinocyte re-epithelialization. Prog Clin Biol Res. 1991; 365:129-40. View in: PubMed

Acquired epidermolysis bullosa. A bullous disease associated with autoimmunity to type VII (anchoring fibril) collagen. Dermatol Clin. 1990 Oct; 8(4):717-26. View in: PubMed

Characterization of "neo-dermis" formation beneath cultured human epidermal autografts transplanted on muscle fascia. J Invest Dermatol. 1990 Jul; 95(1):20-6. View in: PubMed

Treatment of photoaged skin with topical tretinoin increases epidermal-dermal anchoring fibrils. A preliminary report. JAMA. 1990 Jun 13; 263(22):3057-9. View in: PubMed

Enhanced synthesis of collagenase by human keratinocytes cultured on type I or type IV collagen. J Invest Dermatol. 1990 Mar; 94(3):341-6. View in: PubMed

Characterization of cellular elements in healed cultured keratinocyte autografts used to cover burn wounds. Arch Dermatol. 1990 Feb; 126(2):175-80. View in: PubMed

Immunofluorescence on salt-split skin for the diagnosis of epidermolysis bullosa acquisita. Arch Dermatol. 1990 Feb; 126(2):229-31. View in: PubMed

Type IV collagen and fibronectin enhance human keratinocyte thymidine incorporation and spreading in the absence of soluble growth factors. J Invest Dermatol. 1990 Jan; 94(1):139-43. View in: PubMed

Epidermolysis bullosa acquisita in childhood. Differentiation from hereditary epidermolysis bullosa. Arch Dermatol. 1989 Jul; 125(7):944-9. View in: PubMed

Epidermolysis bullosa acquista. Immunol Ser. 1989; 46:547-63. View in: PubMed

Clearing of epidermolysis bullosa acquisita with cyclosporine. J Am Acad Dermatol. 1988 Nov; 19(5 Pt 2):937-42. View in: PubMed

Increased frequency of HLA-DR2 in patients with autoantibodies to epidermolysis bullosa acquisita antigen: evidence that the expression of autoimmunity to type VII collagen is HLA class II allele associated. J Invest Dermatol. 1988 Sep; 91(3):228-32. View in: PubMed

Laminin inhibits human keratinocyte migration. J Cell Physiol. 1988 Jul; 136(1):140-6. View in: PubMed

Review and update of epidermolysis bullosa acquisita. Semin Dermatol. 1988 Jun; 7(2):111-22. View in: PubMed

Human dermal fibroblasts synthesize laminin. J Invest Dermatol. 1988 May; 90(5):679-83. View in: PubMed

Epidermolysis bullosa acquisita antigen is the globular carboxyl terminus of type VII procollagen. J Clin Invest. 1988 Mar; 81(3):683-7. View in: PubMed

Epidermolysis bullosa acquisita antigen: relationship between the collagenase-sensitive and -insensitive domains. J Invest Dermatol. 1988 Feb; 90(2):127-33. View in: PubMed

Human nevocellular nevus cells are surrounded by basement membrane components. Immunohistologic studies of human nevus cells and melanocytes in vivo and in vitro. Lab Invest. 1988 Feb; 58(2):157-62. View in: PubMed

Specific affinity between fibronectin and the epidermolysis bullosa acquisita antigen. J Clin Invest. 1987 Jun; 79(6):1826-30. View in: PubMed

Multiple clear cell acanthomas. Case report and delineation of basement membrane zone antigens. J Am Acad Dermatol. 1987 May; 16(5 Pt 2):1075-8. View in: PubMed

Production of fibronectin by epithelium in a skin equivalent. J Invest Dermatol. 1987 May; 88(5):634-9. View in: PubMed

Malignant pyoderma or pyoderma gangrenosum of the head and neck? Arch Dermatol. Malignant pyoderma or pyoderma gangrenosum of the head and neck? Arch Dermatol. 1987 Mar; 123(3):371-5. View in: PubMed

Localization of the alpha 3 (V) chain of type V collagen in human skin. J Invest Dermatol. 1987 Mar; 88(3):246-52. View in: PubMed

Neonatal foreskin substrate has limitations for the immunofluorescent screening of monoclonal antibodies. J Invest Dermatol. 1987 Feb; 88(2):167-71. View in: PubMed

Importance of the dermal-epidermal junction and recent advances. Dermatologica. 1987; 174(1):1-10. View in: PubMed

Epidermolysis bullosa acquisita antigen, a major cutaneous basement membrane component, is synthesized by human dermal fibroblasts and other cutaneous tissues. J Invest Dermatol. 1986 Aug; 87(2):227-31. View in: PubMed

Epidermolysis bullosa acquisita antigen, a new major component of cutaneous basement membrane, is a glycoprotein with collagenous domains. J Invest Dermatol. 1986 Jun; 86(6):668-72. View in: PubMed

Organ-specific, phylogenetic, and ontogenetic distribution of the epidermolysis bullosa acquisita antigen. J Invest Dermatol. 1986 Apr; 86(4):376-9. View in: PubMed

Adult human keratinocytes migrating over nonviable dermal collagen produce collagenolytic enzymes that degrade type I and type IV collagen. J Invest Dermatol. 1986 Apr; 86(4):418-23. View in: PubMed

Epidermolysis bullosa acquisita antigen is synthesized by human keratinocytes cultured in serum-free medium. Biochem Biophys Res Commun. 1985 Aug 15; 130(3):1267-72. View in: PubMed

Spreading and enhanced motility of human keratinocytes on fibronectin. J Invest Dermatol. 1985 Aug; 85(2):125-30. View in: PubMed

Epidermolysis bullosa acquisita of the immunopathological type (dermolytic pemphigoid). J Invest Dermatol. 1985 Jul; 85(1 Suppl):79s-84s. View in: PubMed

Evidence that anti-basement membrane zone antibodies in bullous eruption of systemic lupus erythematosus recognize epidermolysis bullosa acquisita autoantigen. J Invest Dermatol. 1985 Jun; 84(6):472-6. View in: PubMed

A mouse monoclonal antibody against a newly discovered basement membrane component, the epidermolysis bullosa acquisita antigen. J Invest Dermatol. 1985 Mar; 84(3):215-7. View in: PubMed

Cutaneous wound healing: a model for cell-matrix interactions. J Am Acad Dermatol. 1985 Feb; 12(2 Pt 2):420-33. View in: PubMed

Epidermolysis bullosa acquisita--a pemphigoid-like disease. J Am Acad Dermatol. 1984 Nov; 11(5 Pt 1):820-32. View in: PubMed

Identification of the skin basement-membrane autoantigen in epidermolysis bullosa acquisita. N Engl J Med. 1984 Apr 19; 310(16):1007-13. View in: PubMed

Identification and partial characterization of pemphigoid antigen extracted from normal human skin. J Invest Dermatol. 1984 Jan; 82(1):108-11. View in: PubMed

Epidermolysis bullosa acquisita: an autoimmune disease with distinctive immunoultrastructural features. Cutis. 1983 Dec; 32(6):521-7. View in: PubMed

Structure and function of basement membrane. J Invest Dermatol. 1982 Jul; 79 Suppl 1:69s-72s. View in: PubMed

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